Abstract: A method of quantifying fluorescent dyes labeled on extracellular vesicles, including providing an extracellular vesicle molecule labeled with a fluorescence dye molecule, and determining a brightness of each of the extracellular vesicle molecule labeled with the fluorescence dye molecule and the fluorescence dye molecule through fluorescence correlation spectroscopy (FCS) of the extracellular vesicle molecule and the fluorescence dye molecule.

Abstract: The present disclosure relates to a cell culture device. An aspect of the present disclosure may include a culture medium supply unit including a base, a first reservoir disposed on the base and having an accommodation space, which accommodates the culture medium and has one surface in which a through hole through which the culture medium is discharged is formed, and a culture medium control member disposed to pass through the through hole and configured to control a flow of the culture medium discharged from the first reservoir.

Abstract: The present disclosure relates to a low-level laser therapy device using a light-emitting diode (LED) endoscope cap. One aspect of the present disclosure may include a catheter formed to extend so as to be inserted into a body of a patient and including an air insufflation part for stretching the mucosal folds of the duodenum of the patient, an endoscope cap having a through hole therein to allow the catheter to be inserted therethrough, a hood disposed in one region outside the endoscope cap and disposed such that at least one region thereof protrudes forward from the endoscope cap, and one or more LEDs disposed on each of the endoscope cap and the hood.

Abstract: An electrically assisted pressure joining apparatus and an electrically assisted pressure joining method join a first metal member and a second metal member together, and includes an electrode portion, an intermediate portion including a plurality of micropores and inserted between a first metal member and a second metal member, and a pressure portion connected to the electrode portion to receive a current from the electrode portion and transfer the current to the first metal member and the second metal member to apply a pressure to the first metal member such that the first metal member and the second metal member are joined together by the intermediate portion.

Abstract: A pacemaker lead for cerclage pacing includes a lead fixing part including a fixing tip whose diameter becomes gradually smaller toward an end of a distal part thereof, a plurality of bipolar electrodes that come into close contact with heart muscle, in an outer circumference of the lead fixing part, and a guide wire insertion through hole through which a guide wire can be inserted thereinto, a lead body part configured to be extended to the lead fixing part, having a stylet insertion through hole formed therein, and a body fixing part formed in a bent shape so as to be fixed to an inner wall of the coronary sinus, and a stylet inserted into the stylet insertion through hole, enabling the pacemaker lead for cerclage pacing to be easily moved within the body of the patient.

Abstract: The present invention relates to a method for predicting a state of an object on the basis of dynamic image data and a computing device performing same, the method enabling initial dynamic image data and delay image data to be predicted by performing learning on the basis of dynamic image data captured at a time point when both blood flow image information and disease-specific biological information are included, and furthermore, enabling blood flow image information and disease-specific biological information of the object to be provided.

Abstract: The present invention relates to an anti-ROS1 antibody improved in specificity for ROS1 and a use thereof and, more particularly, provides an anti-ROS1 antibody or an antigen-binding fragment thereof and a use thereof in cancer diagnosis.

Abstract: The present invention relates to a pharmaceutical composition comprising a progesterone-induced blocking factor (PIBF) protein as an active ingredient for prevention or treatment of inflammatory disease. In the present invention, menopausal asthma animal models have been experimentally identified to decrease airway inflammation when treated with PIBF protein. Thus, the composition can be advantageously used in postmenopausal female asthma patients.

Abstract: A catheter apparatus for photodynamic therapy includes: a catheter movable to a lesion site of tissues; a stent installed to be inserted into and retracted from an end of the catheter such that a length thereof is adjustable, and coated with a photosensitizer, and an optical fiber inserted into the catheter to be movable to be positioned at a central portion of the stent. The optical fiber irradiates the photosensitizer with a laser to activate the photosensitizer in a state where the stent is pulled out from the catheter and expanded.

Abstract: Provided are a device, method and program for searching and training a preferred retinal locus of a patient with visual field damage. The method comprises the steps of: providing first stimulation to a patient by means of a stimulation providing device linked to the device; receiving, from the patient, a response with respect to the first stimulation by means of the stimulation providing device; if the response is correct, analyzing the movement of the patient's head corresponding to the first stimulation; specifying a preferred retinal locus on the basis of the analysis result; performing training associated with the patient's central fixation; and performing training associated with reinforcement of the patient's preferred retinal locus.

Abstract: The present invention relates to an apparatus and method for providing virtual reality-based eye movement exercise and visual perception training, wherein a dichoptic presentation is provided in consideration of the deviation of a user's eyeball so as to prevent additional damage to stereoscopic vision due to suppression, and is provided by adjusting the degree of difficulty by changing the locations of visual stimuli on the basis of the level of deviation and training capability of the user, thus making it possible for the user to not only receive training suitable for the user's condition, but also simultaneously undergo visual perception training including eye exercise (movement) training and stereoscopic perception recognition.

Abstract: A myocardium image analysis method comprising acquiring a target image including precontrast-enhanced myocardium, based on a type of coronary artery related to the myocardium, distinguishing the myocardium included in the target image, using an artificial neural network, providing information on the distinguished myocardium, wherein the artificial neural network is trained based on a training database generated by matching images for training of precontrast-enhanced coronary artery and myocardium and images for training of postcontrast-enhanced coronary artery and myocardium.

Abstract: There is provided an apparatus for predicting hypotension of a subject. The apparatus comprises a memory configured to store one or more instructions and a pre-trained hypotension prediction model; and a processor configured to execute the one or more instructions stored in the memory, wherein the instructions, when executed by the processor, cause the processor to: determine an arterial blood pressure data of the subject, input the arterial blood pressure data of the subject into the hypotension prediction model, and determine whether the subject has hypotension using an output result of the hypotension prediction model.

Abstract: The present invention relates to a composition for the differential diagnosis of malignant peripheral nerve sheath tumor (MPNST), a differential diagnosis kit comprising same, a method for providing information required for differential diagnosis of MPNST using same, a method for screening materials for preventing, alleviating, and treating MPNST, and the like. Using the composition capable of detecting the protein marker of the present invention has the effect of making it possible to predict and diagnose whether a malignant tumor has occurred in a patient with neurofibromatosis type 1.

Abstract: The present disclosure relates to a method of providing information for predicting a treatment response to an immune checkpoint inhibitor in a cancer patient by using multiplex immunohistochemistry, wherein, by performing multiplex immunohistochemistry on tumor tissue of a cancer patient to measure an expression level of an immune checkpoint molecule by an automated method, the treatment response to the immune checkpoint inhibitor in the cancer patient can be accurately and quickly predicted. In addition, unlike existing methods using single immunohistochemistry, the disclosed method can reduce errors of an inspector by analyzing markers simultaneously expressed in a single cell and evaluating the same by an automated method, and thus will be widely used as a companion diagnostic method for an immune checkpoint inhibitor.

Abstract: A method for treating an inflammatory skin disease, including administering to a subject in need thereof a pharmaceutical composition containing Ruminococcus gnavus as an active ingredient. A method for treating an inflammatory skin disease, including applying to a subject in need thereof a cosmetic composition containing Ruminococcus gnavus as an active ingredient.

Abstract: A method for treating a cell damage-related disease, including administering a composition to a subject in need thereof. The composition contains, as an active ingredient, one or more selected from the group consisting of stem cells genetically engineered to overexpress a carcinoembryonic antigen-related cell adhesion molecule (CEACAM) family protein, cells differentiated from the stem cells, and components derived from the stem cells.

Abstract: A deep learning-based stent prediction method including: setting as a region of interest, a region in which a procedure is to be performed among blood vessel regions of a target patient, and obtaining a first intravascular ultrasound (IVUS) image, which is a preprocedural IVUS image of the region of interest, obtaining a plurality of first IVUS cross-sectional images into which the first IVUS image is divided at predetermined intervals, extracting feature information about procedure information of the target patient, obtaining mask image information in which a blood vessel boundary and an inner wall boundary are distinguished from each other, with respect to the plurality of first IVUS cross-sectional images, and predicting progress of a stent procedure containing a postprocedural area of a stent for the target patient, by inputting, into an artificial intelligence model, the plurality of first IVUS cross-sectional images, the feature information, and the mask image information.

Abstract: A method of analyzing a plaque tissue component based on deep learning, the method including: extracting a plurality of first intravascular ultrasound (IVUS) cross-sectional images into which a first IVUS image that is a preprocedural IVUS image of a patient is divided at predetermined intervals; labeling each of the plurality of first IVUS cross-sectional images by using label indices corresponding to plaque tissue components to form labeled images, performing image conversion to obtain a polar coordinate image through which a distribution of tissue components for each angle is identifiable by performing a coordinate transformation based on the labeled images, extracting a label vector for each angle based on the polar coordinate image, and outputting output data obtained by quantifying the tissue components for each angle by using an artificial intelligence model that is trained by using, as training data, the label vector for each angle.

Abstract: A method for calculating a coronary artery calcium score, the method comprising acquiring a target image for a coronary artery and myocardium before contrast enhancement, identifying the coronary artery included in the target image by using an artificial neural network, calculating a coronary artery calcium score based on the identified coronary artery, wherein the artificial neural network is trained based on a training database generated via alignment between a pre-acquired image of a coronary artery and myocardium before contrast enhancement and a pre-acquired image of a coronary artery and myocardium after contrast enhancement.