Abstract: Disclosed is a graft for a biological tube including a graft having a hollow of a specific length, having openings at opposite ends along a lengthwise direction thereof, and being contractible, and the graft is contracted to be adhered to outer peripheral surfaces of biological tubes when heat is applied to the graft in a state, in which portions of the biological tubes are inserted into the openings of the graft.

Abstract: Disclosed is a device for providing visual perception training including a display module, and a controller for acquiring at least one target area corresponding to at least one of a first cell of a left eye visual field map and a second cell of a right eye visual field map, and providing a visual perception task to the at least one target area. In the providing of the visual perception task, the controller displays, through the display module, a task object for receiving a response of a patient and fixing a central visual field of the patient, displays, through the display module, at least one stimulus object at at least one stimulus position corresponding to the at least one target area, and acquires the response of the patient related to the task object.

Abstract: The present invention relates to a Pde6b-deficient animal model of retinal degeneration produced by engineered endonucleases, and a method for producing the same. In the animal model of retinal degeneration according to the present invention, only a specific target gene can be removed using engineered endonucleases, so that mutagenesis can be stably achieved. In addition, it is possible to produce a congenital animal model through genetic manipulation at the embryonic stage rather than through acquired factors, which allows for production of an animal model that uniformly exhibits symptoms of the disease in question without being influenced by other factors.

Abstract: A method for predicting a pulmonary disease includes acquiring a three-dimensional computed tomography (CT) image from two-dimensional CT images, each of which captures a respective body position of a first patient, dividing the three-dimensional CT image into a plurality of regions to obtain region-based three-dimensional CT images configured to be used for fractal analysis, calculating a region-based fractal dimension value indicating a fractal complexity of a respective region-based three-dimensional CT image among the generated region-based three-dimensional computed tomography images, adding additional information to the region-based fractal dimension value to generate high-dimensional data, and generating status information of the first patient based on the complexity of the generated high-dimensional data.

Abstract: Provided are a genetically modified immunocyte expressing a chimeric antigen receptor (CAR) comprising an antigen binding domain specifically binding to cancer cells and/or expressing TRAIL, a composition for preventing or treating cancer, the composition comprising the immunocytes, a cell therapeutic agent, a method of providing information for cancer diagnosis, and a method of preparing the genetically modified immunocyte.

Abstract: A compound represented by the following Formula 1 or a pharmaceutically acceptable salt thereof: where R1 is a chelating agent labeled with a metallic radioisotope. A thrombus imaging composition including the compound or the pharmaceutically acceptable salt thereof labeled with a metallic radioisotope as an active ingredient.

Abstract: The present invention relates to: a composition for stabilizing a radiopharmaceutical, the composition comprising a vitamin B compound as an active component; and a radiopharmaceutical composition comprising the same. Due to the inclusion of the vitamin B compound, it is possible to stabilize the radiochemical purity of the radioactive compound by inhibiting the radioactive degradation thereof at room temperature as well as at high temperature.

Abstract: A nanostructure-based substrate for surface-enhanced Raman spectroscopy and a method for manufacturing the same are provided. The method for manufacturing the nanostructure-based substrate for surface-enhanced Raman spectroscopy includes preparing a substrate, depositing a zinc oxide (ZnO) seed layer on the substrate, growing a zinc oxide nanostructure through a synthesis manner of applying a zinc (Zn) solution to the zinc oxide (ZnO) seed layer, and coating the grown zinc oxide nanostructure with a metal.

Abstract: Disclosed is a rectum expanding balloon catheter. The rectum expanding balloon catheter includes a catheter body having a rectum insertion part inserted into a rectum and a gripping part extending from the rectum insertion part in a lengthwise direction thereof and that is used to insert the rectum insertion part into the rectum, and in which a fluid flow passage, along which a fluid flows, is formed in an interior thereof, a balloon that expands and contracts an area on an outside of the rectum insertion part and that locates the rectum insertion part in the rectum, and a stopper provided in the catheter body, and that restricts a length, by which the catheter body is inserted into the rectum, while being adhered to a periphery of an anal passage.

Abstract: Provided are an analytical method of providing an information for diagnosis of a patient who exhibits a response to preoperative chemoradiotherapy in a rectal cancer patient, wherein the expression levels of nine genes, i.e., FGFR3, GNA11, H3F3A, IL12A, IL1R1, IL2RB, NKD1, SGK2, and SPRY2 genes, is analyzed in combination, in carcinoma tissues of a rectal cancer patient, the response (susceptibility) to preoperative chemoradiotherapy can be predicted with high accuracy, and therefore the combination of said genes can be usefully applied as a biomarker for selecting a rectal cancer patient who exhibits a response to preoperative chemoradiotherapy.

Abstract: The present disclosure relates to an apparatus for closed reduction of a bone fracture. The apparatus includes at least: a pulling adaptor including: a handle configured to be gripped by an operator; an insertion rod that is extended from the handle in a longitudinal direction of the handle, and configured to be inserted into the bone fracture which is depressed in at least one area thereof; and a pulling lug that is bent and extended from an end of the insertion rod such that a longitudinal direction of the pulling lug is perpendicular to a longitudinal direction of the insertion rod or such that the pulling lug is inclined with respect to the insertion rod, the pulling lug being configured to be inserted into the at least one depressed area of the bone fracture, in order to pull the bone fracture.

Abstract: The present invention relates to a S1PR4-targeting composition for preventing or treating non-alcoholic steatohepatitis and, more particularly, to a pharmaceutical composition and a health functional food composition, both comprising a sphingolipid compound which serves as a functional inhibitor against S1PR4, showing prophylaxis and therapy of non-alcoholic steatohepatitis. The sphingolipid compound of the present invention is expected to be applied as a leading material effective for the prevention or treatment of non-alcoholic steatohepatitis (NASH) as it has the effect of reducing the infiltration of inflammatory cells into hepatic tissues and suppressing fibrosis and decreases a level of liver injury (ALT), inflammation in hepatic tissues, the expression of a fibrosis-related gene.

Abstract: The present invention relates to a method for providing visual perception training using visual perception learning, the method comprising the steps of: obtaining a field-of-view map having a plurality of unit regions to which a vision index reflecting a user's vision ability is assigned; providing a first session using a visual perception task which is performed by displaying a first visual object for central fixation of the user's field of view and a second visual object in the vicinity of the first visual object, and requests the user's response related to at least the second visual object; determining a vision ability changed region among the plurality of unit regions on the basis of the user's response from the first session; and providing a second session using the visual perception task.

Abstract: Disclosed is a device for providing visual perceptual training including an output module and a controller that controls the output module such that the output module outputs an instruction message informing a trainee of a rule related to visual perceptual training, provides a training session for the visual perceptual training, and stores a result in the training session for evaluating cognitive ability of the trainee, wherein the controller may, in the training session, control the output module such that the output module sequentially displays visual objects, check a type of a response of the trainee, determine whether the checked response is correct according to the rule including the first condition and the second condition based on the attribute of the visual object, the display order of the visual object, and the type of the checked response, and output a feedback indicating that the checked response is correct.

Abstract: A hydrogel stent for cerebral aneurysm includes a hydrogel polymer, and a stent body wrapping at least a portion of the hydrogel polymer. The stent body is expandable in a cerebral aneurysm of a blood vessel. The stent body is provided in a mesh type surrounding at least a portion of the hydrogel polymers. An embolization device for cerebral aneurysm, includes a hydrogel stent for cerebral aneurysm; a micro-conduit providing a movement path for guiding the hydrogel stent to a cerebral aneurysm of a blood vessel; and a pusher wire connected to the hydrogel stent to be movable in the movement path.

Abstract: The present invention is advantageous in that the shape of the catheter can be sensed by detecting the position of bending of the catheter body, the direction thereof, the angle thereof, and the curvature thereof through a triplet calculation of information regarding three wavelengths that have undergone a transition along respective FBGs provided on three optical cores.

Abstract: A stent for anastomosis of different kinds of organs includes a main body, and at least one fixing unit provided in the main body. At least a portion of the main body is inserted into one of different kinds of organs to be anastomosed with each other, and the rest of the main body is inserted into the other of the different kinds of organs. A distance between the different kinds of organs under the anastomosis is maintained by the fixing units.

Abstract: The disclosure purposes to provide an optical coherence tomography (OCT)-based system for diagnosing a high risk lesion such as a vulnerable atheromatous plaque by using an artificial intelligence model through deep learning. A deep learning-based diagnostic method of diagnosing a high risk lesion of a coronary artery includes: acquiring an OCT image of a coronary artery lesion of a patient; extracting a first feature of a thin cap from the OCT image; setting a region of interest included in the OCT image on a basis of the first feature; and determining whether the region of interest includes a high risk lesion.

Abstract: Provided are a diagnostic device and a diagnostic method for predicting fractional flow reserve (FFR) and diagnosing coronary artery lesions via a coronary angiography-based machine learning algorithm. A deep learning-based diagnostic method for diagnosing an ischemic lesion includes: obtaining an angiography image of a patient's blood vessel; extracting a region of interest (ROI) from the angiography image; acquiring diameter information of the blood vessel in the ROI; extracting morphological features of the blood vessel based on the diameter information; and obtaining a predictive FFR value by inputting the morphological features to an artificial intelligence (AI) model and determining whether a lesion is an ischemic lesion.

Abstract: Disclosed are an oral fixation device for radiation therapy and an oral fixation method in treatment of a lip cancer. The oral fixation device for radiation therapy includes a first spacer including a first insert inserted between a first lip portion and a first gum portion, and a tooth support coupled to the first spacer at a side of the first spacer disposed inwardly of an oral cavity, wherein teeth or gums of a patient is supported on the tooth support, wherein a first spacer has a specific thickness to maintain a specific spacing between the first lip portion and the first gum portion, wherein the first lip portion includes a treatment target portion to be subjected to the radiation therapy.