Abstract: A surgical tool control apparatus according to an embodiment comprises: a housing; and a control assembly including a frame connected to the housing, and a first roller module, a second roller module, and a third roller module which are installed on the frame, wherein the second roller module can horizontally move toward the first roller module so that a first surgical tool can be held between the first roller module and the second roller module, and can horizontally move toward the third roller module so that a second surgical tool can be held between the second roller module and the third roller module.

Abstract: A method of treating a pulmonary or airway fibrosis disease, including administering to a subject in need thereof a pharmaceutical composition. The pharmaceutical composition includes a progranulin (PGRN) protein or an active fragment thereof as an active ingredient, and a vector containing a polynucleotide encoding the progranulin (PGRN) protein or the active fragment thereof, or a cell containing the vector.

Abstract: The present invention may provide a method for producing induced pluripotency stem cell-derived mesenchymal stem cells (IFN?-iMSC) pretreated with interferon-gamma; induced pluripotency stem cell-derived mesenchymal stem cells pretreated with interferon-gamma prepared by the method; a pharmaceutical composition for preventing or treating skin diseases, and a cosmetic composition for preventing or improving skin diseases, comprising culture thereof or exosome (IFN?-iMSC-exo) isolated therefrom as an active ingredient. When the composition of the present invention is used, it is possible to provide a composition for skin diseases and a stem cell therapeutic agent, which have an improved immunomodulating function over conventional mesenchymal stem cells.

Abstract: A method for predicting brain disease state change is disclosed. The method includes acquiring test images obtained by capturing a portion of a human brain at a time interval, performing a pre-processing procedure of converting the test images into test voxels configured to be processed for image analysis, wherein a respective test voxel of the test voxels is composed of three-dimensional voxel units, mapping first and second test voxels selected from the test voxels acquired from a patient, with each other on a three-dimensional voxel unit, wherein the first test voxel is acquired at a first time-point and the second test voxel is acquired at a second time-point, generating a voxel-based data-set based on the mapped first and second test voxels, extracting a change in the test voxels using a deep neural network, and generating a state change probability model based on the change in the test voxels.

Abstract: A method for treating a retinal or choroidal disease including administering a composition containing an actin alpha 2 (ACTA2) inhibitor as an active ingredient to a subject in need. The composition is administered by one or more routes selected from the group consisting of oral, subcutaneous, intraperitoneal, intrapulmonary, intranasal, intramuscular, intravenous, intraarterial and topical ocular administration.

Abstract: A method for enhancing immunity, including administering a composition containing a Prevotella stercorea strain or a culture solution thereof to a subject in need thereof. A method for increasing an anticancer effect, including administering a composition containing a Prevotella stercorea strain or a culture solution thereof to a subject in need thereof. A method for treating cancer, including administering a composition containing a Prevotella stercorea strain or a culture solution thereof, and an immune checkpoint inhibitor to a subject in need thereof.

Abstract: A method of ameliorating or treating a retinal or choroidal disease, the method including: administering a composition containing a plasmalemma vesicle-associated protein (PLVAP), an expression or activity activator of the PLVAP protein, or a nucleotide sequence encoding the PLVAP protein, to a subject in need thereof. The composition is formulated for administering to the subject via one or more routes selected from the group consisting of oral, subcutaneous, intraperitoneal, intrapulmonary, intranasal, intramuscular, intravenous, intraarterial and topical ocular administration.

Abstract: An organometallic compound represented by Formula 1, an organic light-emitting device including the organometallic compound, and a diagnostic composition including the organometallic compound are provided: M1(L11)n11(L12)n12??Formula 1 wherein, in Formula 1, L11 may be a ligand represented by Formula 1-1, and the other substituents may be understood by referring to the descriptions thereof provided in the detailed description:

Abstract: The present invention relates to a method, a device, and a program for calculating a brachytherapy plan, and a brachytherapy apparatus. The method comprises: a step in which a computer obtains the number of radiation irradiation spots on the basis of radiation irradiation information (a radiation irradiation spot number obtaining step (S200)); a step in which the computer obtains target area information from a body model of a patient generated on the basis of medical image data of the patient (a target area information obtaining step (S400)); and a therapy plan calculating step (S600) in which the computer calculates, on the basis of the radiation irradiation information and the target area information, the radiation irradiation spots to which radiation is irradiated and the time length of irradiation to each radiation irradiation spot.

Abstract: An artificial blood vessel complex includes: an artificial blood vessel tube member having a tube shape; and an artificial blood vessel ring member provided at an end of the artificial blood vessel tube member, for suturing with an aortic root through a suture, and having a curved shape with an inflection portion to correspond to a shape of an edge of the aortic root. The artificial blood vessel tube member includes: an artificial blood vessel tube portion; and a lounge tube portion extending from an end of the artificial blood vessel tube portion to be separated into a plurality of pieces, and having an end formed in a curved shape to match the artificial blood vessel ring member.

Abstract: An Akkermansia muciniphila AK32 (Accession No. KCTC 14172BP) strain. The Akkermansia muciniphila AK32 strain prevents or improves intestinal damage. A method for preventing, improving or treating intestinal damage, including administering to a subject an effective amount of the Akkermansia muciniphila AK32 strain or a culture thereof as an active ingredient.

Abstract: A medical image learning method of a medical image process apparatus includes preparing a plurality of body X-ray images for learning as an input of a learning data set, preparing internal diagnostic indicator information corresponding to each of the plurality of body X-ray images for learning as a label of the learning data set, and learning an artificial neural network model using the learning data set. The internal diagnostic indicator information includes information on a cardiovascular border. The information on the cardiovascular border includes information on at least one of an aortic knob, a pulmonary conus, a left atrial appendage, an upper right cardiac border, a lower right cardiac border, a lower left cardiac border, a descending aorta, a carina, an upper end point of a diaphragm, a right pulmonary artery, a posterior cardiac border, and an anterior spinal border.

Abstract: A method for manufacturing an implant for implantation into a human body, includes preparing a mold having an inner space part so as to have an inner shape corresponding to a defective portion in a human body; injecting silicone foam into the space part of the mold; curing the silicone foam while applying pressure to same; and removing the mold.

Abstract: An antibody or antigen-binding fragment thereof specifically binding to galectin 3-binding protein (LGALS3BP), and a use thereof, is described. The antibody or antigen-binding fragment thereof may comprise heavy chain CDRs and light chain CDRs of specific sequences. The antibody specifically binding to LGALS3BP has been found to inhibit cancer growth and metastasis in an animal model with cancer and may be effective for alleviating or treating cancer.

Abstract: Disclosed is a suction type stabilizer for a lens including a probe mount, in which a lens is disposed in an interior thereof and an opening that contacts a specimen is formed on one side thereof, an elastic body interposed between the lens and the probe mount, that elastically supports the lens, and defining a division space between the lens and the opening, and a negative pressure forming part forming a negative pressure while suctioning air accommodated in the division space and attaching and fixing the specimen to the opening.

Abstract: Provided is an apparatus for manufacturing a surgical guide that guides a cutting line formed to surround a tumor of an organ, the apparatus including: an organ modeling unit configured to model a 3-dimensional (3D) image of the organ, based on an image of a patient captured by an external imaging apparatus; a cutting line determining unit configured to determine, in the 3D image of the organ, the cutting line to correspond to a location of the tumor and an entry angle of a surgical instrument to the cutting line; and a guide manufacturing unit configured to manufacture a surgical guide that guides the surgical instrument to the cutting line in a slanting manner corresponding to the entry angle, based on the 3D image of the organ.

Abstract: The present invention may provide a pharmaceutical composition for preventing or treating skin diseases, a cosmetic composition for preventing or improving skin diseases, and a stem cell therapeutic agent, which comprise an induced pluripotent stem cell-derived mesenchymal stem cell (iMSC), a culture thereof, or an exosome isolated from an iMSC or iMSC culture as active ingredients. When the composition of the present invention, etc. is used, it is possible to provide a composition for improving, preventing or treating skin diseases and a stem cell therapeutic agent which have an improved immunomodulating function over conventional mesenchymal stem cells.

Abstract: The present disclosure relates to a method for selecting a clinical trial subject using an apparatus. a plurality of first data corresponding to a plurality of first candidate subjects are extracted from medical data stored in a database by using a first query. a plurality of second candidate subjects are selected from among the plurality of first candidate subjects by using a second query corresponding to the plurality of first data and a plurality of variable conditions. a plurality of third candidate subjects are selected from among the plurality of second candidate subjects based on the displaying of information corresponding to at least a part of second data corresponding to the plurality of second candidate subjects. the clinical trial subject is selected based on the displaying of information corresponding to at least a part of third data corresponding to each of the plurality of third candidate subjects.

Abstract: The present disclosure relates to an apparatus and a method for matching an employer to a job seeker based on a metaverse platform. According to the present disclosure, various experts are collected through an expert (user) pool, such that the knowledge and the experience are shared. The needs of the expert and the enterprise looking for the expert are satisfied through the expert platform. Information on the user is protected based on a blockchain technology.

Abstract: The microfluidic chip according to an embodiment of the present invention may include a plate, a bridge channel formed in intaglio on one side of the plate, an inlet formed through the plate to communicate with one end of the bridge channel, an outlet formed through the plate to communicate with the other end of the bridge channel, and at least one well extending in an outward direction of the plate from the bridge channel to provide a space, wherein the bridge channel may be in the form of a curved line, a bent line, an arc, a circle, a spiral, or a polygon.