Abstract: Compositions including an antibody single-chain variable fragment (scFv) conjugate that specifically binds to ROR1 tumor-associated antigen are provided. The anti-ROR1 scFv antibody and conjugates may include a biologically-active molecule. Such conjugates may comprise a chimeric receptor to direct T cells to respond to ROR1 cancer cells, Methods to use the scFV conjugates to target cells expressing ROR1 for therapeutic and diagnostic purposes are also provided.

Abstract: A metal-assisted chemical imprinting stamp includes a porous polymer substrate and a noble metal coating formed directly on the porous polymer substrate. Fabricating the metal-assisted chemical imprinting stamp includes providing a porous polymer substrate, and disposing a noble metal on the porous polymer substrate. Metal-assisted chemical imprinting includes positioning a silicon substrate in an etching solution, contacting a surface of the silicon substrate with a stamp comprising a noble metal layer on a surface of a porous polymer substrate, and separating the silicon substrate from the stamp to yield a pattern corresponding to the noble metal layer on the silicon substrate.

Abstract: Disclosed are fast cell allocation scheduling device and method for a mobile node in a 6TiSCH network, in which when link quality of the mobile node is changed, a fixed path directed to a route node is allocated to establish a movement-route node fixed path minimizing a delay time between the mobile node and the route node.

Abstract: An antenna measurement system includes an array of antennas, an array of reflectors, and a measurement surface. The array of antennas includes a plurality of antenna elements arranged in a straight line; any two adjacent antenna elements in the above antenna elements are separated by a predetermined distance, and each of the antenna elements in the above antenna elements has a radiator and a feed point. The array of reflectors includes at least one reflector and is arranged in a width direction or a height direction, and the array of reflectors is configured to generate a reflection signal according to a signal sent by the array of antennas. An antenna to be measured is configured to perform a measurement operation on the reflection signal on the measurement surface.

Abstract: The present invention provides a compound, a salt thereof, or a prodrug thereof as a compound effective for preventing and/or treating fibrosis, the compound being represented by formula (1) (wherein A is an optionally substituted benzene ring; B is optionally substituted aryl or optionally substituted heteroaryl; X is an oxygen atom or a sulfur atom; Y is a nitrogen atom or a carbon atom; of Y is a single or double bond when Y is a carbon atom, or of Y is a single bond when Y is a nitrogen atom; each R1 independently represents lower alkyl, or two R1s may be bound to each other to form a spiro ring or a crosslinked structure, or two R1s may be bound to each other to form a saturated fused heterocycle together with nitrogen and carbon atoms constituting a ring containing Y; p is 0, 1, or 2; or (R1)p is oxo).

Abstract: The disclosure relates to methods and compositions to treat an eosinophilic disease or disorder. More particularly, the disclosure provides methods and compositions for treating eosinophilic esophagitis.

Abstract: The present invention relates to a process for producing a composition comprising an aqueous medium and, disposed in the aqueous medium, a first volume of a first hydrogel, which process comprises: (i) providing a composition comprising a first hydrophobic medium and, disposed in the first hydrophobic medium, a first volume of a first hydrogel; (ii) disposing a volume of an aqueous composition comprising a hydrogel compound around the first volume of the first hydrogel; (iii) allowing the aqueous composition comprising the hydrogel compound to form a gel and thereby forming a hydrogel object, which hydrogel object comprises the first volume of the first hydrogel and a second volume of a second hydrogel, which second volume of the second hydrogel is disposed around the first volume of the first hydrogel; and (iv) transferring the hydrogel object from the first hydrophobic medium to an aqueous medium and thereby producing the composition comprising the aqueous medium and, disposed in the aqueous medium, the fir

Abstract: Described herein are compositions and methods for making and using recombinant bacteria that are capable of regulated attenuation and/or regulated expression of one or more antigens from Clostridium Perfringens as vaccines to prevent necrotic enteritis (NE).

Abstract: Disclosed is a method for operating a communication node supporting a low power mode in a wireless LAN. A method for operating a station, which includes a PCR and a WURx, comprises the steps of: allowing the WURx, which operates in a wake-up state, to receive a wake-up packet from an access point; transitioning an operating state of the PCR from a sleep state to the wake-up state when the wake-up packet is received; allowing the PCR, which operates in the wake-up state, to receive a data frame from an access point; and allowing the PCR to transmit, to the access point, a response to the data frame.

Abstract: The present invention provides a fractional-N frequency synthesizer comprising a divider controller comprising a multistage noise Shaping (MASH) digital delta-sigma modulator comprising L error feedback modulator (EFM) stages, wherein the jth EFM stage is configured to receive as an input the sum of the error of the preceding EFM stage and a high amplitude dither signal derived from the error of the kth EFM stage, where 1?j?k?L.

Abstract: An exemplary integrated nuclear quadrupole resonance-based detection system comprises a front-end device having a hand-held form factor, wherein the front-end device is configured to scan a sample in or near a sample coil using inbuild electronics and acquire a nuclear quadrupole resonance measurement. The system further includes a swappable sample coil that is attached to an opening at a face of the front-end device and is tuned to a resonant frequency of the sample; and a swappable impedance matching network that is attached to the opening at the face of the front-end device and is configured to tune the resonant frequency of the sample coil. The inbuild electronics comprises a wireless transfer module that is configured to communicate the acquired nuclear quadrupole resonance measurement with a back-end device of the integrated nuclear quadrupole resonance-based detection system. Other systems and methods are also provided.

Abstract: Embodiments disclosed herein provide a system, method, and computer program product for providing a triage classification system. The triage classification system uses a computer model that is developed using historical patient data. The developed computer model is applied to collected patient attribute data from a patient in a pre-hospital setting to generate a triage category. Based on the generated triage category, health care professionals can take desired actions, such as transporting the patient to a facility matching the generated triage category.

Abstract: The invention provides an immunoconjugate comprising an antibody construct which includes an antigen binding domain and an Fc domain, an adjuvant moiety, and a linker, wherein each adjuvant moiety is covalently bonded to the antibody via the linker. Methods for treating cancer with the immunoconjugates of the invention are also described.

Abstract: A method and an apparatus for parallel encoding and decoding of moving picture data are provided. The method includes decoding, from a bitstream, a syntax element indicating that a picture can be decoded using wavefront parallel processing and decoding encoded data of the picture. The step of decoding encoded data of the picture includes for a first coding block of a current CTU row encoded in a palette mode, predicting a palette table for the first coding block by using palette data from a first CTU of a previous CTU row and decoding the first coding block in the palette mode using the palette table predicted for the first coding block.

Abstract: Disclosed is a data sharing method, including: building a trust alliance block chain, the trust alliance block chain comprising a main chain and at least one slave chain; each slave chain corresponding to a domain; and each domain comprising a leader node; establishing a virtual slave chain on the trust alliance block chain; designating, by the leader node in each domain, a node as a federated learning node; assigning, by the leader node in each domain, a virtual identity to the federated learning node to join the federated learning node to the virtual slave chain; and performing, by each federated learning node, a joint training on a local federated learning model using data generated in its own domain to establish a public federated learning model, through which data are shared among the domains. The present disclosure further provides a data sharing system, an electronic device and a storage medium.

Abstract: A session-based recommendation method and device according to one or more embodiments of this disclosure are provided, which use a pre-trained recommendation model to perform item recommend. The method includes following contents: a directed session graph is constructed according to a session to be predicted; the directed session graph is then input into a gated graph neural network which outputs the item embedding vector; a user's dynamic preference is determined according to a user's current preference and a first long-term preference, the current preference is an item embedding vector of a last item in the session and the first long-term preference is determined according to the item embedding vector and an importance score of the item; a prediction score of a respective item is determined according to the dynamic preference and the item embedding vector; and a recommended item is output according to the prediction score of the respective item.

Abstract: Gyroscopes are sensors that measure angular rate and angular orientation. A three-dimensional fused silica micro shell rate-integrating gyroscope is presented. One aspect of the gyroscope includes the use of optical sensors to detect motion of the resonator. The proposed gyroscope is attractive because it achieves several magnitudes higher accuracy as well as high vibration and shock insensitivity from a novel resonator design as well as other unique manufacturing processes.

Abstract: An information processing system includes: a sample data acquisition unit that acquires, for each sample, sample data in which a first cluster and a second cluster are associated with each other, the first cluster including a plurality of sets of a biological element detected from the sample and a biological element quantity indicating a quantity of the biological element, the second cluster including a plurality of sets of a morpheme regarding text describing an environment in which the sample is present and an appearance frequency of the morpheme; and a generation unit that analyzes a plurality of pieces of the sample data with the biological element quantity and the appearance frequency as parameters and generates information indicating a relationship between the environment and the first cluster.

Abstract: A method of fabricating a superconducting-semiconducting stack includes cleaning a surface of a substrate, the substrate comprising a group IV element; depositing an insulating buffer layer onto the substrate, the insulating buffer layer comprising the group IV element; depositing a p-doped layer onto the insulating buffer layer; depositing a diffusion barrier onto the p-doped layer; and processing the superconducting-semiconducting stack through dopant activation.

Abstract: In some examples, a method performed by a drilling rig control center, includes receiving raw data for a first time segment, the raw data related to a drilling operation. In addition, the method includes deriving first drilling state measurements based on the raw data of the first time segment. Further, the method includes deriving first formation state measurements based on the raw data of the first time segment. The method also includes correlating the first derived drilling and formation state measurements of the first time segment with a second derived drilling and formation state measurements of a second time segment. Still further, the method includes generating a control response based on the correlation.