Abstract: A nicotinamide adenine dinucleotide phosphate-dependent steroid dehydrogenase-like (NSDHL) inhibitor provided according to an aspect of the present invention can be used not only as an anticancer agent capable of overcoming resistance to EGFR-targeting anticancer agents, but also advantageously in the treatment of hyperlipidemia.

Abstract: Compositions and methods for treating type II diabetes in a subject. A viral vector is provided which includes a nucleic acid molecule comprising a sequence encoding a propeptide and the active portion of GLP-1, wherein, when expressed, the N-terminal amino acid of GLP-1 immediately follows the C-terminal amino acid of the propeptide. In desired embodiments, the subject is a cat or dog.

Abstract: Provided is a zero-clearance fifth-generation (5G) ultra-wideband (UWB) Multiple-Input Multiple-Output (MIMO) antenna, including a main dielectric substrate, lateral dielectric substrates, and multiple antenna elements, where the lateral dielectric substrates are arranged at two sides of the main dielectric substrate; the multiple antenna elements are arranged on the lateral dielectric substrates; the antenna elements each include a feeding element and a grounding radiator element; the feeding element is provided at an inner side of each of the lateral dielectric substrates; and the grounding radiator element is provided at an outer side of the lateral dielectric substrate.

Abstract: A minimally invasive magnetic vocal fold manipulator system and method is disclosed. Namely, a magnetic vocal fold manipulator system is provided that includes a magnetics-based thyroid cartilage implant, a magnetics-based arytenoid cartilage implant, and an implant introducer device. Additionally, a method is provided of using the minimally invasive magnetic vocal fold manipulator system for performing lateralization and/or medialization of the vocal cord.

Abstract: Among the various aspects of the present disclosure is the provision of compositions and methods for targeted treatment and imaging of cancers or tumors.

Abstract: Provided are core-shell semiconductor nanoparticles, each including a core and a shell disposed on a surface of the core, and emitting light when irradiated with light. The core contains a semiconductor containing M1, M2, and Z, M1 containing at least one selected from the group consisting of Ag, Cu, and Au, M2 containing at least one selected from the group consisting of Al, Ga, In, and Tl, and Z containing at least one selected from the group consisting of S, Se, and Te. The shell contains a semiconductor containing a Group 13 element and a Group 16 element, and having a greater band-gap energy than the core. The shell has a compound containing a Group 15 element disposed on a surface of the shell, and the Group 15 element containing at least P with a negative oxidation number.

Abstract: In a method for magnetic resonance imaging pseudorandomly undersampled k-space imaging data is acquired with multiple receiver coils of an MRI imaging apparatus. MR image reconstruction is performed to produce a reconstructed MR image from the k-space imaging data by iteratively solving sketched approximations of an original reconstruction problem. The sketched approximations use a sketched model matrix As that is a lower-dimensional version of an original model matrix A of the original reconstruction problem. The sketched model matrix As preserves the Fourier structure of the MR reconstruction problem and reduces the number of coils actively used during reconstruction.

Abstract: Methods of generating an autologous cellular vaccine comprising monocytes or neutrophils and an antigenic polypeptide or nucleotide encoding the antigenic polypeptide are provided. The antigen-loaded cell-based vaccine compositions made using these methods are also provided. Methods of using the antigen-loaded cell-based vaccine compositions are also provided and these vaccines may be used to treat cancer. Kits for carrying out the methods described herein are also provided.

Abstract: The present invention relates to an image encoding/decoding method and apparatus. An image encoding method according to the present invention may comprise generating a transform block by performing at least one of transform and quantization; grouping at least one coefficient included in the transform block into at least one coefficient group (CG); scanning at least one coefficient included in the coefficient group; and encoding the at least one coefficient.

Abstract: The present disclosure discloses a method for modification of mung bean protein and preparation of simulated egg pulp based on the modified protein. A commercial mung bean protein isolate is used as a raw material in the present disclosure, then subjected to pH shift modification, ultrasonic treatment and protein-glutaminase treatment for compound modification to prepare a high-functionality modified mung bean protein isolate; and the modified mung bean protein isolate is used as a raw material, using high-speed emulsification and high-pressure homogenization are conducted to obtain a high-stability mung bean protein-based simulated egg pulp. In the present disclosure, the mung bean protein isolate prepared by compound modification has good solubility, emulsifying property and gelling property. The mung bean protein-based simulated egg pulp is in the form of a stable emulsion and has good fluidity and moderate gelling property, and uniformity and stability can still be maintained for a long time.

Abstract: Devices for radiative cooling and optical waveguiding are provided, wherein the devices comprise a fabric including one or more fibers extending for a length in a longitudinal direction and a plurality of void structures positioned within each of the one or more fibers and extended over the length of each of the one or more fibers. Each of the plurality of void structures is configured to scatter at least a portion of an electromagnetic radiation received thereon to thereby radiatively cool the object.

Abstract: Provided is a surveillance system employing a plurality of unmanned aerial vehicles (UAVs), the surveillance system showing improved surveillance performance while optimizing common energy consumption for computing of all the UAVs and also providing a stable visual monitoring service using autonomous mobility of the plurality of UAVs regardless of movement of an object to be monitored and action uncertainty of an adjacent UAV.

Abstract: An object recognition method using queue-based model selection and optical flow in an autonomous driving environment includes preprocessing data through a dense flow in a matrix form by calculating an optical flow of images captured consecutively in time by a sensor for an autonomous vehicle, generating a confidence mask by generating a vectorized confidence threshold representing a probability that there is a moving object for each cell of the preprocessed matrix, determining whether there is a moving object on the images by mapping the images captured consecutively in time to the confidence mask, and selecting an object recognition model using a tradeoff constant between object recognition accuracy and queue stability in each time unit. Accordingly, it is possible to improve the performance of object recognition in an autonomous driving environment by applying the optical flow to the confidence threshold of the object recognition system.

Abstract: Provided for are methods of producing triacylglycerol-accumulated microalgae, methods for making bioplastics from triacylglycerol-accumulated microalgae, methods for making alga-mixed plastics, and products including these bioplastics. Methods of triacylglycerol accumulation using centrifugation are also provided. Products such as plastic beads and other consumer products can be made from the bioplastics described herein.

Abstract: A compound is represented by the following general formula (I): The compound or a salt thereof provides a fluorescent probe for detecting carboxypeptidase activity In the formula, R1 represents an alkyl group having 1 to 6 carbon atoms or an alkoxy group having 1 to 6 carbon atoms; T represents an amino acid residue or a residue of an amino acid derivative; S represents a C-terminal amino acid residue. represents a fluorophore, and the fluorophore is a fluorophore in which an absorption/fluorescence wavelength greatly changes or a quenched state changes to a fluorescent state by elimination of the —P(?O)(—R1)-T-S moiety.

Abstract: The present disclosure relates to a precision seeding apparatus with recesses on a caterpillar for arranging and distributing seeds against bottoms of seed furrows. The apparatus includes a frame; the frame is provided with a seed box with a seed distribution opening; a caterpillar for transporting seeds capable of being connected with a drive mechanism is arranged in the seed box; a lower part of the caterpillar for transporting seeds corresponds to the position of the seed distribution opening; the caterpillar is provided with at least one column of recesses in a lengthwise direction of the caterpillar; each group of recesses is connected through a seed unloading ditch; the seed unloading ditch is formed into a ring in a lengthwise direction of the caterpillar for transporting seeds; a lower part of the caterpillar for transporting seeds is provided with a comb sheet.

Abstract: This document relates to methods and materials for generating oilseed (e.g., pennycress) plants that have oil with reduced levels of polyunsaturated fatty acids (PUFAs) and/or increased levels of oleic acid. For example, oilseed plants having reduced expression levels of one or more polypeptides involved in fatty acid biosynthesis (e.g., fatty acid desaturase 2 (FAD2) and reduced oleate desaturation 1 (ROD1)), as well as methods and materials for making and using such oilseed plants are provided.

Abstract: The invention discloses for the first time pluripotent cells, including induced pluripotent stem cells, embryonic stem cells, hypo-immune pluripotent cells, cells that have been derived therefrom, and cells that have been biologically differentiated therefrom into particular tissue lineages that are ABO blood type O Rhesus Factor negative or otherwise evade rejection resulting from blood type antigen mismatch. The invention further provides universally acceptable “off-the-shelf” pluripotent cells and derivatives thereof for generating or regenerating specific tissues and organs.

Abstract: Provided in the present invention is a method for preparing chiral alkyl compounds by the asymmetric hydrogenation reaction of iron complex catalysts catalysing olefins: using the disubstituted olefin shown in formula I as a raw material, atmospheric hydrogen as a hydrogen source, FeX2-8-OIQ complex as a catalyst, and a silane compound and acetonitrile as cocatalysts, and reacting for 12-24 hours under the action of a reducing agent to prepare the chiral alkyl compound shown in formula II. The method of the present invention has mild reaction conditions, simple operation, and high atom economy. In addition, the reaction does not require the addition of any other toxic transition metal (such as ruthenium, rhodium, and palladium), and has great practical application value in the synthesis of drugs and materials. The conversion rate of the reaction is also good, generally reaching >99%, and the enantioselectivity is also high, generally 70-99%.

Abstract: The specification relates generally to the post-genomic identification of therapeutic targets and agents. In particular the specification relates to PSMD9 inhibitors and methods for preventing or treating metabolic disorders such as fatty liver disease that are associated with dysregulation of lipid homeostasis.