Abstract: Among the various aspects of the present disclosure is the provision of molecular sensors, microbial sensors, constructs, systems, and methods for selectively detecting aromatic compounds.

Abstract: Disclosed herein is a novel compound of formula (I) for detecting circulating cancerous cells, particularly, cholangio-cancerous cells, from a biological sample, wherein, R1 and R2 are independently H, or —SO3M; and M is a monovalent cation selected from the group consisting of sodium ion, potassium ion, lithium ion or ammonium ion. Also disclosed herein is a method of treating and detecting cholangio-cancerous cells from a biological sample of a subject suspected of having cholangiocarcinoma (CCA). The method includes steps of, contacting the biological sample with a magnetic bead pre-coated with the compound of formula (I); detecting a complex formed between the magnetic bead and the biological sample in an immunoassay; and administering to the subject an effective amount of a chemotherapeutic agent to ameliorate symptoms associated with the CCA.

Abstract: A fuel cell bipolar flow field plate and a fuel cell stack are provided. The fuel cell bipolar flow field plate includes a first gas channel and a second gas channel. Each of the gas channels has several sub-channels, each of the sub-channels has bending parts, and adjacent sub-channels have opposite flow directions. The sub-channels of the two gas channels form a four-leaf clover type pattern in a reaction area of the fuel cell bipolar flow field plate. A bending angle of each of the bending parts in the four-leaf clover type pattern is within 90 degrees.

Abstract: The present invention provides a fusion polypeptide comprising a target polypeptide moiety and a self-aggregating peptide moiety, and a method of producing and purifying a target polypeptide by expressing the fusion polypeptide.

Abstract: There is provided a multi-layered membrane comprising a top layer, a bottom layer, and a spacer layer; wherein said spacer layer is interposed between said top layer and said bottom layer; wherein said top layer, said bottom layer and said spacer layer are each independently composed of one or more selective layers, each selective layer comprising a 2D material; wherein said spacer layer comprises at least one channel for receiving a fluid; wherein said bottom layer comprises a hole with an area in the range of 1 ?m2 to 1 mm2; and wherein said hole is capable of being in fluid communication with said at least one channels of said spacer layer. There is also provided a method to synthesize the top layer of a multi-layered membrane as disclosed herein, methods for separating a plurality of ions or molecules in a fluid stream, a device comprising a multi-layered membrane as disclosed herein, and use of the method or the device as disclosed herein in osmotic power generation.

Abstract: An apparatus, system, and method for filtering and assaying a fluid sample are described. In an embodiment, the apparatus includes a filtration unit comprising: a filter bracket shaped to removably couple with a fluid sample cup and a vacuum container; and a filter housing cooperatively couplable to the filter bracket and comprising a filter configured to filter fluid passing through the filter bracket; and an assay device shaped to cooperatively couple with the filter housing and comprising a porous matrix positioned to be in fluidic communication with the filter when the filter housing is cooperatively coupled with the assay device.

Abstract: A pDNA-based vaccine against SARS-CoV-2 and methods for preventing or treating COVID-19 using it.

Abstract: Among the various aspects of the present disclosure is the provision of a biological and biochemical production of piperazic acid derived from the newly discovered production pathway for L-piperazic acid. One aspect of the present disclosure includes a transgenic microorganism (e.g., bacteria) engineered to accumulate piperazic acid and derivatives thereof, including a piperazic acid (Piz)-containing product. Another aspect of the present disclosure includes biochemical and biological methods for producing piperazic acid and derivatives thereof, including a piperazic acid (Piz)-containing product. Another aspect of the present disclosure includes compositions and methods of using isotopically labeled piperazic acid and derivatives thereof, including a piperazic acid (Piz)-containing product.

Abstract: An interferometric demodulation system for a large capacity fiber grating sensing network is provided by the present disclosure, comprising: a continuous light output end of the nanoscale wide-spectrum light source is connected to an input end of the pulse optical modulator, an output end of the reference grating is connected to an input end of the grating array sensing network, and a third communication end of the optical circulator is connected to an input end of the optical amplifier, an output end of the optical amplifier is connected to an input end of the Mach-Zehnder interferometer, three-channel signal output ends of the Mach-Zehnder interferometer are respectively connected to signal input ends corresponding to the embedded signal processor through the photoelectric converter, and the embedded signal processor controls the heating device to control a temperature of an any one of interference arms of the Mach-Zehnder interferometer.

Abstract: A flexible multifunctional cross-linking adhesive, a preparation method therefor and an application thereof. The adhesive uses guar gum and carboxyl styrene butadiene rubber as raw materials, and is formed by intermolecular cross-linking between hydroxyl groups rich in the guar gum and carboxyl groups contained in the carboxyl styrene butadiene rubber to form a flexible multifunctional cross-linked network. Compared to the prior art, the water-based adhesive is a flexible cross-linking adhesive that has a strong bonding force, high mechanical strength, and no cracking due to tensile deformation, and is insoluble in a battery electrolyte. The adhesive may effectively accommodate the volume effect of a sulfur positive electrode and keep the positive electrode structure intact during a cycling operation. At the same time, the adhesive has significant advantages such as environmental friendliness and being low cost.

Abstract: According to an embodiment, there is provided a method of manufacturing a molded body from a waste material including at least one of food waste and seaweed, the method comprising: preparing dry powder made from at least the waste material; and forming a molded body by pressurizing the dry powder in a state in which the dry powder is heated to a predetermined temperature.

Abstract: Aspects of the invention include a method for synthesizing a peptide brush polymer, the method comprising: exposing a mixture comprising peptide-containing monomers, one or more photoinitiators, and one or more chain transfer agents to a light sufficient to induce photopolymerization, and photopolymerizing the peptide-containing monomers in the mixture; wherein: the resulting peptide brush polymer comprises at least one peptide-containing polymer block; the at least one peptide-containing polymer block is characterized by a degree of polymerization of at least 10 and a peptide graft density of 50% to 100%; and at least one peptide moiety of the at least one peptide-containing polymer block has 5 or more amino acid groups.

Abstract: The present invention belongs to the field of microbiology, and particularly relates to an application of a Pseudomonas aeruginosa vaccine in prevention and treatment of burn and scald complicated with bacterial infection. The burn and scald of the present invention include burns and scalds, and degree of the scalds includes I degree, superficial II degree, deep II degree, or III degree scalds. Site of the scalds includes skin, mucosa or other tissues. The Pseudomonas aeruginosa vaccine of the present invention can effectively prevent and treat burn and scald complicated with Pseudomonas aeruginosa infection caused by multidrug-resistant Pseudomonas aeruginosa by activating the specific immune response of the body.

Abstract: The present invention relates to a method for forming a protective coating on a plant tissue following the consecutives steps of: (a) providing a plant having an external surface, wherein a portion of the external surface includes an exposed surface; (b) applying a first aqueous solution that contains a crosslinking agent to the external surface of the plant; and (c) applying to the external surface of the plant a second aqueous solution that contains a polysaccharide which is susceptible to crosslinking by the crosslinking agent, thereby forming a protective coating on the exposed surface of the plant. Further provided is a postharvest plant matter that includes a first segment covered by natural skin, and a second segment having an exposed surface that is coated by a protective coating that contains a polysaccharide with the first segment being essentially free of the protective coating.

Abstract: Methods of producing hybrid fibrous scaffolds are provided. The methods include dissolving a polymer, such as polydioxanone, in a solution, such as 1,1,1,3,3,3-hexafluoro-2-propanol (HFP), to form a polymer-containing solution. The method comprises electrically charging the polymer-containing solution. The method comprises writing the polymer-containing solution on a counter electrode or a ground in a grid pattern to form semi-stable fibers comprised of the polymer, the semi-stable fibers vary between bent and straight and forming the hybrid fibrous scaffold. The writing may be performed by a 3D printer. The resulting scaffolds and methods of using the same are also disclosed herein.

Abstract: An end-to-end trainable grouped mathematically differentiable non-maximal suppression (NMS) technique is presented for monocular 3D object detection. First, formulate NMS as a matrix operation and then group and mask the boxes in an unsupervised manner to obtain a simple closed-form expression of the NMS. This technique addresses the mismatch between training and inference pipelines and, therefore, forces the network to select the best 3D box in a differentiable manner. As a result, the proposed technique achieves state-of-the-art monocular 3D object detection results on the KITTI benchmark dataset performing comparably to monocular video-based methods.

Abstract: [Problem] To provide a composition or the like that suppresses the physical destruction of red blood cells (hemolysis) due to exercises and behaviors associated with impact such as striking, for example, as when continually hitting the soles of the feet on the ground by continued running, by using astaxanthin which has a long history of use as a food, and to provide a composition or the like for making the number of red blood cells destroyed (hemolysis number) to lower than the number of red blood cells newly created by hematopoiesis (hematopoiesis number), to suppress and/or improve exercise-induced hemolytic anemia caused by the physical destruction of red blood cells (hemolysis). [Solution] Astaxanthin is used as an active ingredient.

Abstract: The present invention relates to compositions, methods, and kits for eliciting an immune response to at least one CMV antigen expressed by a cancer cell, in particular for treating and preventing cancer. CMV determination methods, compositions, and kits also are provided.

Abstract: Provided herein are novel devices for the formation of arteriovenous fistulas, which may aid subjects in need of hemodialysis. The novel devices are provided in a non-surgical procedure, greatly decreasing the cost and increasing the convenience of placing an arteriovenous fistula. The devices are atraumatic, and consist of a sutureless anastomosis device and conduit. Methods and tools for placing the devices in vivo are disclosed, including a magnetic-assisted method.

Abstract: A light supply method and a light supply system for phototherapy are provided. The light supply method includes the following. A plurality of light emitting modules of a light source device are driven so that a light source device outputs a first light. The first light is sensed by a light sensing module. A light parameter corresponding to best physiology of a user is received. A light output ratio of the light emitting modules is adjusted based on the light parameter, thereby adjusting the first light to a second light. The light emitting modules respectively have different central wavelengths. A half-height width of a plurality of spectra of the light emitting modules is less than 30 nanometers.