Patents Assigned to University
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Patent number: 11497820Abstract: The present technology provides compounds, as well as compositions including such compounds, useful for imaging and/or treatment of a glioma, a breast cancer, an adrenal cortical cancer, a cervical carcinoma, a vulvar carcinoma, an endometrial carcinoma, a primary ovarian carcinoma, a metastatic ovarian carcinoma, a non-small cell lung cancer, a small cell lung cancer, a bladder cancer, a colon cancer, a primary, gastric adenocarcinoma, a primary colorectal adenocarcinoma, a renal cell carcinoma, and/or a prostate cancer.Type: GrantFiled: September 9, 2020Date of Patent: November 15, 2022Assignee: Cornell UniversityInventors: John W. Babich, James M. Kelly, Alejandro Amor-Coarasa, Shashikanth Ponnala
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Patent number: 11503292Abstract: The present invention provides a method for encoding a video signal on the basis of a graph-based separable transform (GBST), the method comprising the steps of: generating an incidence matrix representing a line graph; training a sample covariance matrix for rows and columns from the rows and columns of a residual signal; calculating a graph Laplacian matrix for rows and columns on the basis of the incidence matrix and the sample covariance matrix for rows and columns; and obtaining a GBST by performing eigen decomposition of the graph Laplacian matrix for rows and columns.Type: GrantFiled: February 1, 2017Date of Patent: November 15, 2022Assignees: LG Electronics Inc., University of Southern CaliforniaInventors: Hilmi E. Egilmez, Yung-Hsuan Chao, Antonio Ortega, Bumshik Lee, Sehoon Yea
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Patent number: 11499948Abstract: Described herein are devices and methods of use thereof, the devices comprising: a sample conduit providing a path for fluid flow extending from a sample inlet to a sample outlet; a thermal housing enclosing the sample conduit, the thermal housing comprising a plurality of measurement regions; and a motorized stage translatable along the thermal housing so as to align a detector with one or more of the plurality of measurement regions. The devices can continuously flow a fluid precursor sample from the sample inlet to the sample outlet, the fluid precursor sample comprising a first precursor and a second precursor, such that the first precursor reacts with the second precursor as the fluid precursor sample continuously flows from the sample inlet to the sample outlet to form the sample before reaching the sample outlet, wherein the sample comprises a plurality of particles or an organic molecule.Type: GrantFiled: September 11, 2018Date of Patent: November 15, 2022Assignee: North Carolina State UniversityInventors: Milad Abolhasani, Robert W. Epps, Kobi C. Felton
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Patent number: 11500109Abstract: A computer architecture for geolocation spoofing/meaconing detection is disclosed. According to some aspects, a computer accesses an incoming geolocation positioning signal. The computer determines, using a signal characteristics calculation subsystem, geolocation positioning signal characteristics for the incoming geolocation positioning signal. The computer provides, using a geolocation positioning spoofing/meaconing detection subsystem, the geolocation positioning signal characteristics as an input vector to a neural network, wherein the neural network determines whether the incoming geolocation positioning signal is legitimate or fake. If the incoming geolocation positioning signal is determined to be fake: the computer computes, using a Bayesian inference subsystem, a likelihood and a severity of a geolocation positioning technology based attack. The computer provides, as a digital transmission, an indication of whether the incoming geolocation positioning signal is legitimate or fake.Type: GrantFiled: March 28, 2019Date of Patent: November 15, 2022Assignees: Raytheon Company, University of North DakotaInventors: Naima Kaabouch, Mohsen Riahi Manesh, Jonathan R. Kenney
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Patent number: 11497671Abstract: An apparatus (10) for the rehabilitation, assistance and/or augmentation of arm strength in a user (U) comprises a support arrangement (12) for supporting the apparatus (10) on the user (U), a linkage arrangement (14) coupled to the support arrangement (12) and for coupling to an arm (A) of the user (U), and an actuation arrangement (16) for operating the linkage arrangement (14) and thereby manipulating the user's arm (A) in response to a user input signal.Type: GrantFiled: October 2, 2018Date of Patent: November 15, 2022Assignee: University of StrathclydeInventors: Heba Lakany, Lijo Varughese Chacko
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Patent number: 11498769Abstract: The invention employs a folding arm conveyor that rotates horizontally. The folding arm conveyor is mainly composed of an undercarriage mounted on the ground of a stockyard, a tower body mounted on the undercarriage, a balance arm, a conveying arm, a tower top, and other main components, wherein the balance arm, the conveying arm, and the tower top are mounted on the tower body. The conveying arm is provided with two portal frames (I) and (II) and an unloading trolley. The tower body is provided with a gyration apparatus and a hopper. The balance arm is provided with a balance trolley. The folding arm conveyor can rotate horizontally, and the conveying arm can be folded and retraced by controlling the wind rope by the windlass, so that the folding arm conveyor can be prevented from colliding with other devices or buildings during the rotation.Type: GrantFiled: November 19, 2019Date of Patent: November 15, 2022Assignee: Changsha University of Science and TechnologyInventors: Juan Huang, Lairong Yin, Tao Ling, Le Xiao, Jinxing Wang, Yuyang Peng, Peng Xu, Minhui Chen
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Patent number: 11502741Abstract: A method for deploying an electromagnetic wave guiding structure includes a communication dead zone analysis step and an improvement measure determination step. In the former step, a frequency band in use and an electromagnetic wave signal strength threshold value are preset, and a processing module creates an electromagnetic map for the electromagnetic wave intensity over an area in the frequency band in use based on an electronic map of the area, wherein the electromagnetic map shows a communication dead zone. In the latter step, the processing module obtains an existing electromagnetic wave path according to the electromagnetic map and infers from the existing electromagnetic wave path the installation position and type of at least one electromagnetic wave guiding structure assembly suitable for use to guide the electromagnetic wave to the communication dead zone and ensure that the coverage ratio of the electromagnetic wave in the area reaches a threshold value.Type: GrantFiled: July 12, 2021Date of Patent: November 15, 2022Assignee: National Chung Cheng UniversityInventors: Sheng-Fuh Chang, Chia-Chan Chang, Shih-Cheng Lin, Yuan-Chun Lin
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Patent number: 11499228Abstract: An anode includes: (1) a current collector; and (2) an interfacial layer disposed over the current collector. The interfacial layer includes a film of a layered material and a reinforcing material selectively disposed over certain regions of the film, while other regions of the film remain exposed from the reinforcing material.Type: GrantFiled: June 19, 2018Date of Patent: November 15, 2022Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Yi Cui, Jin Xie, Lei Liao
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Patent number: 11499904Abstract: An apparatus and method for testing dissolution properties of a drug, especially anti-inflammatory drugs administered by aerosol into the respiratory system. The apparatus shortens the time it takes for a drug to dissolve and thus provides for rapid testing of new drugs for quality control as well as for regulatory purposes. It is suitable for evaluating bioequivalence or to study the pharmacokinetics of drugs administered into the respiratory system. This method shortens dissolution times for testing a drug to about 10 and 20 minutes and thus provides for rapid testing.Type: GrantFiled: February 12, 2020Date of Patent: November 15, 2022Assignees: National Guard Health Affairs, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research CenterInventor: Salman Al Fadhel
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Patent number: 11497576Abstract: The present disclosure presents a trajectory array guide system for defining a trajectory to a target location in the brain of a subject and for guiding an elongated tool along the trajectory. The trajectory array guide system can comprise: a base, an array guide, an imaging unit, and an elongated handle configured for connection with a stereotaxic navigation system. The present disclosure presents a method of using a trajectory array guide system for defining a trajectory to a target location in the brain of a subject and for guiding an elongated tool along the trajectory.Type: GrantFiled: July 17, 2018Date of Patent: November 15, 2022Assignees: Voyager Therapeutics, Inc., The Regents of the University of CaliforniaInventors: Adrian Philip Kells, Stefan Schreck, Edward H. Luttich, Kenneth A. Bloch, Krystof Bankiewicz
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Patent number: 11497754Abstract: The present disclosure is directed to a composition for prevention or treatment of neurodegenerative conditions. The composition comprises a neurosteroid, a synthetic enantiomer of a neurosteroid, or a combination thereof.Type: GrantFiled: February 5, 2020Date of Patent: November 15, 2022Assignee: Washington UniversityInventors: Douglas Covey, Charles Zorumski, Yukitoshi Izumi, Makoto Ishikawa
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Patent number: 11497788Abstract: Provided herein are glycosylated peptide amphiphiles (GPAs), supramolecular glyconanostructures assembled therefrom, and methods of use thereof. In particular, provided herein are glycosaminoglycan (GAG) mimetic peptide amphiphiles (PAs) and supramolecular GAG mimetic nanostructures assembled therefrom that mimic the biological activities of GAGs, such as heparin, heparan sulfate, hyaluronic acid etc.Type: GrantFiled: September 23, 2020Date of Patent: November 15, 2022Assignee: Northwestern UniversityInventors: Samuel I. Stupp, Bo Timmy Bjorn Fyrner, Sung Soo Lee
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Patent number: 11499195Abstract: There is described herein a method of prognosing and/or predicting disease progression and/or in subject with prostate cancer, the method comprising: a) providing a sample containing mitochondrial genetic material from prostate cancer cells; b) sequencing the mitochondrial genetic material with respect to at least 1 patient biomarker selected from CSB1, OHR, ATP8 and HV1 (hypervariable region 1); c) comparing the sequence of the patient biomarkers to control or reference biomarkers to determine mitochondrial single nucleotide variations (mtSNVs); and d) determining the a prostate cancer prognosis; wherein a relatively worse outcome is associated with the presence of mtSNVs in CSB1, OHR, ATP8 and a relatively better outcome is associated with the presence of mtSNVs in HV1.Type: GrantFiled: June 2, 2017Date of Patent: November 15, 2022Assignees: Ontario Institute for Cancer Research, University Health NetworkInventors: Julia A. Hopkins, Paul Boutros, Robert G. Bristow
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Patent number: 11502176Abstract: Techniques in accordance with embodiments described herein are directed to semiconductor devices including a layer of aluminum nitride AlN or aluminum gallium nitride AlGaN as a ferroelectric layer and a method of making a thin film of AlN/AlGaN that possesses ferroelectric properties. In a ferroelectric transistor, a thin film of AlN/AlGaN that exhibits ferroelectric properties is formed between a gate electrode and a second semiconductor layer, e.g., of GaN.Type: GrantFiled: November 3, 2020Date of Patent: November 15, 2022Assignees: Taiwan Semiconductor Manufacturing Co., Ltd., National Taiwan UniversityInventors: Miin-Jang Chen, Tzong-Lin Jay Shieh, Bo-Ting Lin
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Patent number: 11502473Abstract: A laser apparatus includes an optic dispersion compensator. In another aspect, an optic (40, 45) uses phase wrapping to compress or stretch a laser pulse. A further aspect includes an apparatus and method for binary-phase compression of stretched laser pulses. In yet another aspect, a single monolithic transmissive or reflective optic (40, 45) provides compression or stretching of a laser pulse using a sinusoidal pattern for introducing binary steps. Another aspect provides a stretching or compressing optic (40, 45) for retarding a phase of multiple frequency regions of a laser pulse by a factor of 2? or less. Still another aspect employs a volume grating or multi-layer mirror including phase wrapping to obtain discontinuous phase jumps in a laser pulse compressor (45) or stretcher (40). Methods of using or making the laser apparatus are also provided.Type: GrantFiled: August 29, 2018Date of Patent: November 15, 2022Assignee: Board of Trustees of Michigan State UniversityInventors: Marcos Dantus, Vadim Lozovoy
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Patent number: 11497730Abstract: The disclosure provides methods for treating estrogen receptor positive (ER+) cancer in women with an effective amount of lasofoxifene, a pharmaceutically acceptable salt thereof, or a prodrug thereof. The disclosure also includes the detection of the Estrogen Receptor 1 (ESR1) gene mutations that lead to endocrine resistance and treatment of endocrine resistant ER+ cancers.Type: GrantFiled: April 9, 2019Date of Patent: November 15, 2022Assignee: Duke UniversityInventors: Kaitlyn Andreano, Ching-yi Chang, Donald P. McDonnell, Stephanie L. Gaillard
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Patent number: 11499902Abstract: A force sensing probe (100) for sensing snap-in and/or pull-off force of a liquid droplet (111) brought into and/or separated from contact with a hydrophobic sample surface (151), respectively, comprises: a sensing tip (101); a sensor element (102) connected to the sensing tip, capable of sensing sub-micronewton forces acting on the sensing tip in a measurement direction; and a droplet holding plate (104) having a first main surface (105) and a hydrophilic second main surface (106) connected via a peripheral edge surface (107), and being attached via the first main surface to the sensing tip (101) perpendicularly relative to the measurement direction for receiving and holding a liquid droplet (111) as attached to the second main surface; the droplet holding plate comprising an electrically conductive surface layer (115), the first and the second main surfaces and the peripheral edge surface being defined by the surface layer.Type: GrantFiled: January 17, 2018Date of Patent: November 15, 2022Assignee: Aalto University Foundation srInventors: Quan Zhou, Robin Ras, Ville Liimatainen, Maja Vuckovac
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Patent number: 11502956Abstract: A method for content caching in information centric network virtualization includes receiving, by a first node, a first data packet; in response to a cache distance identifier hop of the first data packet being less than a preset maximum cache distance, setting hop=hop+1 and sending the first data packet to a next node by the first node; in response to the hop being not less than the preset maximum cache distance and there being available cache space in the first node, setting hop=0, storing the first data packet, and sending the first data packet to the next node by the first node. The node determines whether to cache a data packet based on the cache distance identifier of the data packet, which comprehensively considers the cache energy consumption caused by caching the data packet in the node and the transmission energy consumption caused by transmission of the data packet in the link, thereby effectively reducing the total energy consumption of the network.Type: GrantFiled: March 22, 2019Date of Patent: November 15, 2022Assignee: Chongqing University of Posts and TelecommunicationsInventors: Qilie Liu, Xiaoxiao Wang, Liqiang Zhuge, Yanyu Wang, Zheng Li, Bin Cao, Jingcheng Liu, Fengfan Yang
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Patent number: 11498906Abstract: A method of fixating carbon dioxide (CO2) to a substituted oxazolidinone. The method includes mixing a metal-organic framework (MOF), a co-catalyst, at least one para-substituted aromatic amine, and at least one epoxide to form a mixture. The method further includes contacting the mixture with a gas stream containing CO2 to react the CO2 in the gas stream with the epoxide and para-substituted aromatic amine to form a substituted oxazolidinone mixture. The MOF is a UiO-66-X MOF, where X is of formula (I) wherein at least one of R1 to R4 is an allyloxy group, and R1 to R4 are independently an allyloxy group or a hydrogen.Type: GrantFiled: April 25, 2022Date of Patent: November 15, 2022Assignee: King Fahd University of Petroleum and MineralsInventors: Aasif Helal, Muhammad Usman, Mahmoud Mohamed Abdelnaby, Md. Eyasin Arafat
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Patent number: 11500043Abstract: A magnetoencephalograph M1 includes: multiple pump-probe type optically pumped magnetometers 1A; a bias magnetic field forming coil 15 for applying a bias magnetic field in the same direction as a direction of pump light of each of the multiple pump-probe type optically pumped magnetometers 1A and in a direction approximately parallel to a scalp; a control device 5 that determines a current for the bias magnetic field forming coil and outputs a control signal corresponding to the determined current; and a coil power supply 6 that outputs a current to the bias magnetic field forming coil in response to the control signal output from the control device.Type: GrantFiled: June 14, 2021Date of Patent: November 15, 2022Assignees: HAMAMATSU PHOTONICS K.K., Kyoto UniversityInventors: Akinori Saito, Takahiro Moriya, Takenori Oida, Motohiro Suyama, Tetsuo Kobayashi