Abstract: A polymer composition includes a conductive polymer and at least one stretchability and electrical conductivity (STEC) enhancer, wherein a content of the STEC enhancer in the composition is at least about 1 wt. % of the composition.
Type:
Grant
Filed:
January 13, 2017
Date of Patent:
November 15, 2022
Assignee:
The Board of Trustees of the Leland Stanford Junior University
Abstract: A fluid system includes a membrane module including a first section and a second section that are separated by a semipermeable membrane, a feed pump connected to the first section, a draw pump connected to the second section, a load connected to the second section, a flush valve, and an electronic control unit (ECU) configured to control one or more of the feed pump, the draw pump, the flush valve, and the load. The ECU may be configured to control the feed pump, the draw pump, the flush valve, and/or the load according based on or according to net power generation.
Abstract: A composition of an omega-3 polyunsaturated fatty acid (PUFA)-taxoid conjugate formulated in an oil-in-water nanoemulsion (NE) drug delivery system in combination with an immune-oncology (IO) agent to enhance therapeutic efficacy in refractory cancers, such as PDAC. A method of treating cancer, by administering an effective amount of a pharmaceutical composition including an omega03 PUFA-taxoid conjugate in combination with an IO agent encapsulated in an NE drug delivery system to a subject in need of treatment, and treating cancer.
Type:
Grant
Filed:
December 19, 2018
Date of Patent:
November 15, 2022
Assignees:
TargaGenix, Inc., The Research Foundation for The State University of New York, Northeastern University
Inventors:
James E. Egan, Mansoor Amiji, Iwao Ojima
Abstract: The document discloses transferrable hyperbolic metamaterial particles (THMMP) that display broadband, selective, omnidirectional absorption and can be transferred to secondary substrates, allowing enhanced flexibility and selective transmission. A device having metamaterial nanostructures includes a substrate and metamaterial nanostructures engaged to the substrate to form an optical layer to interact with light incident to the optical layer to exhibit optical reflection or absorption or transmission that is substantially uniform over a spectral range of different optical wavelengths associated with materials and structural features of the metamaterial nanostructures, each metamaterial nanostructure including different material layers that are interleaved to form a multi-layer nanostructure.
Type:
Grant
Filed:
January 23, 2018
Date of Patent:
November 15, 2022
Assignee:
The Regents of the University of California
Inventors:
Donald J. Sirbuly, Zhaowei Liu, Conor Riley
Abstract: An antenna configured to transmit or receive a signal is provided. The antenna includes a substantially transparent base substrate and an antenna electrode on the substantially transparent base substrate. The antenna electrode includes a substantially transparent conductive layer, and a first conductive line abutting an edge portion of the substantially transparent conductive layer and electrically connected to the edge portion of the substantially transparent conductive layer. An electrical conductivity of the first conductive line is greater than an electrical conductivity of the substantially transparent conductive layer.
Type:
Grant
Filed:
June 17, 2019
Date of Patent:
November 15, 2022
Assignees:
BOE Technology Group Co., Ltd., Beijing University of Posts and
Telecommunications
Abstract: The present invention generally relates to specific immune-modulatory RNA species that have a small hairpin structure (shRNA), and that can bind to retinoic acid inducible gene I receptor (RIG-I). In particular, said RNA species comprise a nucleotide insertion to create a kink in the stem region. Also encompassed are compositions comprising such shRNA, for use as antiviral or anticancer medication, or as adjuvants in vaccine.
Type:
Grant
Filed:
January 17, 2019
Date of Patent:
November 15, 2022
Assignees:
Nanyang Technological University, Agency for Science, Technology and Research
Inventors:
Dahai Luo, Katja Fink, Hui Yee Yong, Chin Yong Victor Ho
Abstract: The invention relates to a virus-like particle (VLP) based vaccine. The virus-like particle constitutes a non-naturally occurring, ordered and repetitive antigen array display scaffold which can obtain a strong and long-lasting immune response in a subject. The VLP-based vaccine may be used for the prophylaxis and/or treatment of a disease including, but is not limited to, cancer, cardiovascular, infectious, chronic, neurological diseases/disorders, asthma, and/or immune-inflammatory diseases/disorders.
Type:
Grant
Filed:
November 22, 2019
Date of Patent:
November 15, 2022
Assignee:
University of Copenhagen
Inventors:
Adam Frederik Sander Bertelsen, Ali Salanti, Thor Theander, Susan Thrane, Christoph Mikkel Janitzek, Mette Ørskov Agerbaek, Morten Agertoug Nielsen, Jan Tobias Gustafsson
Abstract: The present invention provides methods and compositions for treating and preventing lung injuries due to or associated with coronavirus infections that cause Severe Acute Respiratory Syndrome, including COVID-19. More specifically the present invention provides methods for treating or preventing the lung injuries associated with SARS-CoV-2 infections, such as acute lung injury (ALI), lung fibrosis, and acute respiratory distress syndrome (ARDS). The methods comprise administering a therapeutically effective amount of a pharmaceutical composition comprising a protein kinase inhibitor compound having MAP3K2/MAP3K3 inhibition activity, such as pazopanib or nintedanib, or a pharmaceutically acceptable salt, solvate, or prodrug thereof, to a patient in need thereof. The present invention also provides devices for administering the compositions.
Abstract: A thrust balancing apparatus for a pump includes a housing, a balancing chamber, a connecting tube, a balancing disk, a bushing, a washer, and a pair of upthrust washers. The balancing chamber defines an upper cavity and a lower cavity. The connecting tube is configured to establish fluid communication between the balancing chamber and an exterior of the housing. A first portion of the balancing disk is disposed within the upper cavity. A second portion of the balancing disk passes through the lower cavity. A third portion of the balancing disk is external to the balancing chamber. The washer is disposed between the balancing disk and the bushing. The pair of upthrust washers are disposed between the balancing disk and the balancing chamber.
Type:
Grant
Filed:
August 24, 2020
Date of Patent:
November 15, 2022
Assignees:
Saudi Arabian Oil Company, King Fahd University of Petroleum & Minerals
Abstract: Methods and apparatus for obtaining a vibrational circular dichroism (VCD) image using a discrete frequency infrared (DFIR) microscope are disclosed. The method includes generating a pulsed laser beam comprising a spectral frequency, which may be tunable; modulating the laser beam to generate circularly polarized light; illuminating a sample and collecting, and detecting an optical signal transmitted or transflected from the location of the sample. The detected signal is demodulated at, for example, both the pulse frequency and the sum or difference of the pulse frequency and the modulating frequency to obtain an intensity value that correspond to the absorbance, and a polarization-dependent value that corresponds to the VCD. Other configurations of the apparatus may be employed to measure VCB and VLD.
Type:
Grant
Filed:
July 15, 2021
Date of Patent:
November 15, 2022
Assignee:
The Board of Trustees of the University of Illinois
Inventors:
Yamuna Phal, Kevin Lee Yeh, Rohit Bhargava
Abstract: A computer-implemented method and a related system for determining seismic hazard related data. The method includes processing geological/seismological data associated with an area of unknown hazard using a simulation model, and determining simulated ground motion intensity data associated with the area of unknown hazard. The simulation model is determined based on geological/seismological data associated with an area of known hazard and ground motion intensity data associated with the area of known hazard. Alternatively, or additionally, the method includes processing simulated ground motion intensity data associated with the area of unknown hazard with another simulation model.
Type:
Grant
Filed:
June 1, 2020
Date of Patent:
November 15, 2022
Assignee:
City University of Hong Kong
Inventors:
Moshe Zukerman, Zengfu Wang, Gang Wang, Yu Wang, Xinyu Wang, William Moran, Qing Wang, Yanni Sun
Abstract: A method and agent to induce accelerated creep deformation of shale rock formations in the annular gap between a shale formation and non-cemented sections of a casing string have been developed. A fluid containing alkali silicate or a modified alkali silicate is added to the annular space between the shale rock formation and the casing string. The alkali silicate promotes creep deformation of the shale rock, effectively closing the annulus surrounding the casing. It has been found lithium silicate provides the strongest shale-casing bond and is the presently preferred material for closing abandoned wells.
Type:
Grant
Filed:
October 23, 2020
Date of Patent:
November 15, 2022
Assignees:
Board of Regents, The University of Texas System, PQ LLC
Abstract: Hybrid tomato varieties designated ‘VT19077208’ and ‘VT19108230’ are disclosed. ‘VT19077208’ and ‘VT19108230’ are hybrid tomato varieties exhibiting stability and uniformity.
Type:
Application
Filed:
April 5, 2022
Publication date:
November 10, 2022
Applicants:
VoloAgri Group, Inc., North Carolina State University
Inventors:
Lakhwinder RANDHAWA, Mario Velasco ALVARADO, Higinio MAYORQUIN
Abstract: The present invention relates to a method for producing a high yield of an organometallic compound including a step of allowing a metal hexacarbonyl compound to react with a hexahydro-1,3,5-triazine compound, and a thin film having excellent properties, fabricated by depositing the produced organometallic compound.
Type:
Application
Filed:
April 18, 2022
Publication date:
November 10, 2022
Applicants:
HANSOL CHEMICAL CO., LTD., Industry-Academic Cooperation Foundation, Yonsei University
Inventors:
Jin-Hyung SEO, Mi-Ra PARK, Jang-Hyeon SEOK, Jung-Woo PARK, Hyung-Jun KIM, Tae-Wook NAM, Yu-Jin LEE
Abstract: The wave number and phase velocity (shear wave speed) of ultrasound energy within an organ of interest are calculated using a herein-disclosed phase gradient calculation method. This calculation method is less sensitive to imperfections in the reverberant field distribution and requires a smaller support window, relative to earlier calculation methods based on autocorrelation. Applications are shown in simulations, phantoms, and in vivo liver.
Abstract: The present disclosure discloses a dynamic equivalent circuit of a combined heat and power system, and a working method thereof. Controlled sources are used to represent a thermoelectric coupling source; equivalent inductance is used to represent a delay of a heat transmission pipeline; equivalent resistance is used to represent a heat load and a heat loss of the heat transmission pipeline; and equivalent capacitance is used to represent a heat storage water tank. A circuit model is used to uniformly represent two thermoelectric heterogeneous energy sources, and a single power simulation tool may be used to simulate a combined heat and power system, so that the simulation system has a simple structure and is easy to develop and maintain.
Abstract: Infections caused by multidrug-resistant (MDR) bacteria, particularly Gram-negative bacteria, are an escalating global t health threat. Often clinicians are forced to administer the last resort antibiotic colistin, however colistin resistance is becoming increasingly prevalent, giving rise to the potential for a situation in which there are no treatment options for MDR Gram-negative infections. The development of adjuvants that circumvent bacterial resistance mechanisms is a promising orthogonal approach to the development of new antibiotics. We recently disclosed that the known IKK-13 inhibitor IMD-0354 potently suppresses colistin resistance in several Gram-negative strains. In this disclosure, we explore the structure activity relationship (SAR) between the IMD-0354 scaffold and colistin resistance suppression, and identify several compounds with more potent activity than the parent against highly colistin resistant strains of Acinetobacter baumannii and Klebsiella pneumoniae.
Type:
Application
Filed:
October 8, 2020
Publication date:
November 10, 2022
Applicant:
University of Notre Dame du Lac
Inventors:
Christian Melander, Alexander WEIG, Akash Kumar BASAK
Abstract: Disclosed are a base station, and a broadband dual-polarized filtering magneto-electric dipole antenna and a radiation unit thereof. A radiation structure includes two dipoles with a polarization direction orthogonal to each other. Each dipole includes two radiators arranged opposite to each other. A balun structure includes four balun assemblies, each balun assembly includes two balun grounds arranged opposite to each other at an interval, and a feeder line and an open-stub arranged opposite to each other at an interval and electrically connected to each other. One balun ground is electrically connected to one radiator, the other balun ground is electrically connected to the other adjacent radiator. The feeder line and one balun ground are arranged opposite to each other at an interval. The open-stub and the other balun ground are arranged opposite to each other at an interval. The balun grounds are arranged between the feeder line and the open-stub.
Type:
Application
Filed:
September 30, 2020
Publication date:
November 10, 2022
Applicant:
South China University of Technology
Inventors:
Xiuyin ZHANG, Shengjie YANG, Yiyang LIU, Yunfei CAO