Abstract: Ferritin or iron-based image enhancement agents identify target tissue for treatment or ablation and are heated by microwave absorption. Microwave heat substrates enhance microwave hyperthermal ablation treatment, and may be percutaneously delivered and imaged by x-ray CT during placement of the microwave treatment antenna, allowing more precise positioning and more complete ablation of a tumor site. One method of treating a target tissue uses image-guided delivery of a heat substrate with a reverse-phase change polymer, and may apply energy to fix a mass of the material in the tissue. The fixed polymer may increase hyperthermia, form a thermal boundary, or blockade a vessel or passage so as to reduce or prevent undesired conductive cooling by contiguous tissue, or may deliver a localized treatment drug at the site, upon heating or as it degrades over time.
Type:
Grant
Filed:
December 5, 2017
Date of Patent:
November 15, 2022
Assignees:
Brown University, Rhode Island Hospital
Inventors:
Damian E. Dupuy, William Keun Chan Park, Edward G. Walsh
Abstract: The present invention is directed to methods and compositions for typing of Lactobacillus buchneri bacterial strains, detecting the presence of a L. buchneri in a sample, identifying a strain of L. buchneri having resistance to an invasive foreign genetic element, modifying the resistance of bacteria and archeae to an invasive foreign genetic element, and introducing nicks into or cleaving double stranded DNA for genome editing.
Type:
Grant
Filed:
January 28, 2020
Date of Patent:
November 15, 2022
Assignee:
North Carolina State University
Inventors:
Rodolphe Barrangou, Alexandra Briner Crawley
Abstract: A magnetoencephalograph M1 includes: multiple pump-probe type optically pumped magnetometers 1A; a bias magnetic field forming coil 15 for applying a bias magnetic field in the same direction as a direction of pump light of each of the multiple pump-probe type optically pumped magnetometers 1A and in a direction approximately parallel to a scalp; a control device 5 that determines a current for the bias magnetic field forming coil and outputs a control signal corresponding to the determined current; and a coil power supply 6 that outputs a current to the bias magnetic field forming coil in response to the control signal output from the control device.
Type:
Grant
Filed:
June 14, 2021
Date of Patent:
November 15, 2022
Assignees:
HAMAMATSU PHOTONICS K.K., Kyoto University
Abstract: Identifying insect species integrates image processing, feature selection, unsupervised clustering, and a support vector machine (SVM) learning algorithm for classification. Results with a total of 101 mosquito specimens spread across nine different vector carrying species demonstrate high accuracy in species identification. When implemented as a smart-phone application, the latency and energy consumption were minimal. The currently manual process of species identification and recording can be sped up, while also minimizing the ensuing cognitive workload of personnel. Citizens at large can use the system in their own homes for self-awareness and share insect identification data with public health agencies.
Abstract: Provided are compositions and methods for selectively reducing the amount of antibiotic resistant and/or virulent bacteria in a mixed bacteria population, or for reducing any other type of unwanted bacteria in a mixed bacteria population. The compositions and methods involve targeting bacteria that are differentiated from other members of the population by at least one unique clustered regularly interspaced short palindromic repeats (CRISPR) targeted DNA sequence. The compositions and methods can be readily adapted to target any bacteria or any bacteria plasmid, or both.
Abstract: This system is designed to color correct a targeted color or colors in a video stream comprising: a computer device having a computer readable medium; and, a set of computer readable instructions embodied on the computer readable medium that are configured to: receive a dataset that includes one or more pairs of video frames where a first frame of the pair of an incorrect color frame and the second frame of the pair is a color correct frame, using a machine learning module to create a mask according to the dataset, receiving an image, correcting the image, and, transmitting the corrected image to a display.
Abstract: An apparatus for testing corrosion can comprise a frame and a rack having a generally planar face, a first edge, and a second edge. The rack can be pivotably coupled to the frame. The apparatus can be configured for selectively orienting the rack to position the first edge of the rack with a select vertical offset with respect to the second edge of the rack.
Abstract: An intrusion detection method and system for Internet of Vehicles based on Spark and combined deep learning are provided. The method includes the following steps: S1: setting up Spark distributed cluster; S2: initializing the Spark distributed cluster, constructing a convolutional neural network (CNN) and long short-term memory (LSTM) combined deep learning algorithm model, initializing parameters, and uploading collected data to a Hadoop distributed file system (HDFS); S3: reading the data from the HDFS for processing, and inputting the data to the CNN-LSTM combined deep learning algorithm model, for recognizing the data; and S4: dividing the data into multiple resilient distributed datasets (RDDs) for batch training with a preset number of iterations.
Type:
Grant
Filed:
October 20, 2021
Date of Patent:
November 15, 2022
Assignee:
Nanjing University of Science and Technology
Abstract: An end and monomer functionalized poly(propylene fumarate) polymer and methods for preparing this polymer, comprising isomerized residue of a maleic anhydride monomer and a functionalized propylene oxide monomer according to the formula: where n is an integer from more than 1 to 100; R is the residue of an initiating alcohol having a propargyl, norbornene, ketone or benzyl functional group; and R? is a second functional group selected from the group consisting of propargyl groups, 2-nitrophenyl groups, and combinations thereof are disclosed. The end and monomer functional groups allow for post-polymerization modification with bioactive materials using “click” chemistries and use of the polymer for a variety of applications in medical fields, including, for example, 3-D printed polymer scaffold.
Type:
Grant
Filed:
February 2, 2018
Date of Patent:
November 15, 2022
Assignee:
University of Akron
Inventors:
Matthew Becker, James A. Wilson, Yusheng Chen
Abstract: Methods, apparatuses, and systems for wireless power transfer (WPT) in ball-and-socket type structures are provided. A ball and ball-socket structure can include conductive windings and conductive plates having a variety of shapes to optimize WPT over different angles as the ball moves or rotates within the ball-socket. One or both of capacitive coupling and inductive coupling can be incorporated.
Abstract: Semiconductor structures involving multiple quantum wells provide increased efficiency of UV and visible light emitting diodes (LEDs) and other emitter devices, particularly at high driving current. LEDs made with the new designs have reduced efficiency droop under high current injection and increased overall external quantum efficiency. The active region of the devices includes separation layers configured between the well layers, the one or more separation regions being configured to have a first mode to act as one or more barrier regions separating a plurality of carriers in a quantum confined mode in each of the quantum wells being provided on each side of the one or more separation layers and a second mode to cause spreading of the plurality of carriers across each of the quantum wells to increase an overlap integral of all of the plurality of carriers. The devices and methods of the invention provide improved efficiency for solid state lighting, including high efficiency ultraviolet LEDs.
Abstract: Disclosed herein are methods and systems of utilizing sequencing reads for detecting and quantifying the presence of a tissue type or a disease type in cell-free DNA prepared from blood samples.
Type:
Grant
Filed:
June 7, 2017
Date of Patent:
November 15, 2022
Assignees:
The Regents of the University of California, University of Southern California
Inventors:
Xianghong Jasmine Zhou, Shuli Kang, Steven Dubinett, Wenyuan Li, Qingjiao Li
Abstract: Provided are methods and apparatuses for packet scheduling for software-defined networking in an edge computing environment. A packet scheduling method according to an exemplary embodiment of the present disclosure comprises: receiving packets arriving at a queue connected to a switch in a software-defined network in an edge computing environment; moving the packets in the queue forward one position based on the order of arrival each time a packet is served by the switch; and if a new packet enters the switch while the buffer in the queue is full, pushing out the packet at the front and putting the new packet at the end of the queue.
Type:
Grant
Filed:
July 10, 2020
Date of Patent:
November 15, 2022
Assignee:
Research & Business Foundation Sungkyunkwan University
Abstract: The present application discloses a supported PtZn intermetallic alloy catalyst, a method for preparing the same and application thereof. The catalyst uses SiO2 as a support and Zn as a promoter, and a small amount of active component Pt is supported; the weight percentage of Pt is 0.025%-1%, and the weight percentage of Zn is 0.025%-1.7%, a co-impregnation method is adopted in preparation, the SiO2 support is impregnated in aqueous solution of chloroplatinic acid and zinc nitrate, and then drying and high-temperature reduction are performed to obtain a PtZn/SiO2 catalyst. The catalyst has the advantages of high activity, high stability, low price and low toxicity. The catalyst provided by the present application is applicable to preparation of alkene through short-chain alkane dehydrogenation, in particular to preparation of propylene through propane dehydrogenation in a hydrogen atmosphere.
Abstract: A light projection system, including a light source to provide an output beam of light, an angular light modulator (ALM) comprising a plurality of pixels, each pixel having an ON state and an OFF state, the ALM positioned to receive output beam on the plurality of pixels, and a processor coupled to the ALM. The processor is programmed to control a first set of the pixels to transition between the OFF state and the ON state while the beam is incident on the pixels. An amount of light is selectively directed in a direction by the first set. The processor is also programmed to control a second set of the plurality of pixels to remain in the OFF state while the beam is incident on the plurality of pixels. As a result, the ALM operates as a spatial light modulator and an angular light modulator of the beam of light.
Type:
Grant
Filed:
December 21, 2018
Date of Patent:
November 15, 2022
Assignee:
Arizona Board of Regents on Behalf of the University of Arizona
Abstract: The present disclosure provides a fine-grained image recognition method, an electronic device and a computer readable storage medium. The method comprises the steps of feature extraction, calculation of feature discriminant loss function, calculation of feature diversity loss function and calculation of model optimization loss function. The present disclosure comprehensively considers influences of factors such as a large intra-class difference, a small inter-class difference, and a great influence of background noise of the fine-grained image, and makes constrains such that the feature maps belonging to each class are discriminative and have the features of corresponding class, thus reducing the intra-class difference, decreasing the learning difficulty and learning better discriminative features.
Type:
Grant
Filed:
September 30, 2020
Date of Patent:
November 15, 2022
Assignee:
Beijing University of Posts and Telecommunications
Abstract: The present application relates to a cell cryopreservation protective composition, the use of the composition, and a cell cryopreservation method. The cell cryopreservation protective composition comprises a zwitterionic molecule having the general formula R1—N+(CH3)2—(CH2)n—R2, wherein R1 is a linear or branched alkyl having 1 to 10 carbon atoms, and is optionally substituted with a substituent; R2 is any negatively charged group selected from the group consisting of —COO?, —SO4?, —SO3?, and (I); and R3 is a group selected from the group consisting of (methyl)acryloyloxyalkyl, alkyl and alkenyl; and the zwitterionic molecule having general formula R1—N+(CH3)2—(CH2)n—R2 is preferably a betaine compound. The cell cryopreservation protective composition can carry out cell cryopreservation in a non-toxic and efficient manner, and results in an extremely high post-thaw cell survival rate and does not require stepwise cryopreservation.
Abstract: A photometric dispensing nozzle unit, a photometric dispensing apparatus, and a photometric dispensing method are for preventing an increase in apparatus scale and have a simple structure to be easily handled. A nozzle performs suction/discharge of gas through a distal end opening and can have a dispensing tip attached thereto. A light guide end portion is provided in the nozzle and can receive or irradiate light at a distal end of the nozzle. A dispensing cylinder has a cylinder having a cavity therein, a plunger that is slidable in the cavity, and a suction/discharge port that performs suction/discharge of gas. A suction/discharge flow path passes through the nozzle and communicates with the suction/discharge port and the distal end opening of the nozzle. A light guide path is optically connected to the light guide end portion through the nozzle but not through the dispensing cylinder.
Abstract: The present invention relates generally to the field of disorders of complement activation. More specifically, the present invention provides methods and compositions useful for diagnosing and treating atypical hemolytic uremic syndrome, antiphospholipid antibody syndrome and other disorders of the alternative pathway of complement activation. In one embodiment, a method comprises the steps of (a) incubating or contacting serum obtained from a patient suspected of having atypical hemolytic uremic syndrome (aHUS) with a glycosylphosphatidylinositol-anchored protein (GPI-AP) deficient cell line; and (b) performing a cell viability assay on the cells from step (a). In a specific embodiment, the method further comprises the step of diagnosing the patient as having aHUS based on a statistically significant increased difference of non-viable cells from the patient serum as compared to a control.
Abstract: Technologies for a microelectromechanical system (MEMS) made up of composable piezoelectric actuators is disclosed. An elongated piezoelectric rod is disposed between a top and a bottom electrode. The top electrode runs along one edge of the top of the piezoelectric rod for a first segment, then runs along the other edge of the top of the piezoelectric rod for the a second segment. When a voltage is applied across the electrodes, the piezoelectric rod bends in a first direction for the first segment and in a second direction opposite the first for the second segment, displacing the tip of the rod. Several such rods can be joined in parallel and/or series, allowing for large-scale systems to be composed.