Patents Assigned to University
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Patent number: 12215132Abstract: Exemplary methods, compositions and uses thereof can be provided for preventing, reducing and/or treating loss of muscle function. In particular, e.g., it is possible to administer to a subject a pharmaceutical composition comprising a therapeutically effective amount of an agent that enhances Interleukin-6 (IL) release during exercise, and optionally a pharmaceutically acceptable carrier or excipient.Type: GrantFiled: October 18, 2021Date of Patent: February 4, 2025Assignees: The Trustees of Columbia University in the City of New York, William Marsh Rice UniversityInventors: Gerard Karsenty, Julian Berger, Han Xiao
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Patent number: 12215175Abstract: The present invention relates to a UV curable water-based polyelectrolyte composition and a method for producing a polyelectrolyte film using the same, which provides a polyelectrolyte composition comprising: at least one polyelectrolyte selected from Formulas 1 to 3; an acrylate-based material; a cross-linker; a photoinitiator; and a solvent.Type: GrantFiled: May 28, 2021Date of Patent: February 4, 2025Assignee: Yonsei University Industry Foundation (Yonsei UIF)Inventors: Jung Hyun Kim, Chan Il Park, Young No Kim, So Young Bae, Min Seok Do, Jeong Min Kim
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Patent number: 12215095Abstract: The present invention relates to new compounds that are useful in the prevention or treatment of respiratory diseases, such as asthma, acute and chronic inflammatory conditions, and fibrotic diseases or conditions in which fibrosis contributes to the pathology of the condition. The invention also relates to the preparation of the compounds, and to compositions including the compounds. The present invention also relates to the use of the compounds, as well as compositions including the compounds, in treating or preventing respiratory diseases, acute and chronic inflammatory conditions, and fibrotic diseases or conditions in which fibrosis contributes to the pathology of the condition.Type: GrantFiled: November 7, 2019Date of Patent: February 4, 2025Assignee: The University of MelbourneInventors: Alastair Stewart, Spencer Williams, Zalihe Hakki
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Patent number: 12218968Abstract: A method and system for detecting and analyzing internet traffic from Internet of Things (IoT) devices is presented. A network telescope is employed to collect unsolicited data packets. The data packets are analyzed to determine whether they arise from a misconfigured device or from a malicious device (darknet sanitization) or from some other source. Traffic from misconfigured devices is filtered out. The data packets from malicious devices are analyzed and a classification model is trained to classify the data packets into originating from an IoT or from a non-IoT device. The classifier is then validated on a separate set of data. The data packets originating from malicious IoT devices are further analyzed by such techniques a clustering (e.g. agglomerative hierarchical clustering), geo-location analysis, methods of attack, and coordination of attacks.Type: GrantFiled: April 11, 2022Date of Patent: February 4, 2025Assignee: Board of Regents, The University of Texas SystemInventors: Elias Bou Harb, Morteza Safaei Pour
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Patent number: 12217609Abstract: An embodiment controller for use in a communication system for platooning vehicles that performs Vehicle-to-Vehicle (V2V) communication through controllers mounted in the platooning vehicles includes a communication unit configured to transmit and receive a message including control and sensor information of the platooning vehicles, a scheduler configured to store message transmission times of the platooning vehicles, and a determiner configured to determine whether a message received through the communication unit corresponds to schedule information stored in the scheduler, wherein the controller is configured to transmit a message in accordance with an order determined based on the schedule information and find out a message transmission order of the platooning vehicles by sharing the schedule information.Type: GrantFiled: October 7, 2021Date of Patent: February 4, 2025Assignees: Hyundai Motor Corporation, Kia Corporation, Korea University Research and Business FoundationInventors: Hyun Sung Jang, Sang Heon Pack, Min Ok Kim, Joon Woo Kim
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Patent number: 12217645Abstract: An operating method of a calibration system for a display device obtains image information about an image displayed on display device and wavelength information about pixels of the image information using a hyperspectral camera included in an electronic device, transmits the obtained image information and wavelength information to a first application in the electronic device, generates calibration data about the obtained image information and wavelength information through the first application and transmits the calibration data to a second application in the display device, and performs color calibration of the display device based on the calibration data transmitted to the second application to display a color calibrated image.Type: GrantFiled: April 19, 2023Date of Patent: February 4, 2025Assignees: SAMSUNG ELECTRONICS CO., LTD., CHUNG ANG University Industry Academic Cooperation FoundationInventors: Unjeong Kim, Hojung Kim, Hyungbin Son, Suyeon Lee
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Patent number: 12214046Abstract: The present disclosure provides compositions comprising protein encapsulated nanoparticles, and methods of making said compositions. In an aspect, a composition may comprise a drug delivery vector and a therapeutic substance, wherein the composition elutes at least 1.0 pg of the therapeutic substance per 100,000 particles of the drug delivery vector over a period of time under conditions of a drug delivery vector release buffer, wherein the therapeutic substance, drug delivery vector and drug delivery vector release buffer comprise a solution, wherein the solution is centrifuged and a portion stored at about 1 to 10° C., and wherein the elution of the therapeutic substance is determined by ELISA assay. This disclosure further describes a method of controlling an immunophenotype in a patient suffering from a disease which impacts the immune system.Type: GrantFiled: June 2, 2022Date of Patent: February 4, 2025Assignee: West Virginia University Board of Governors on behalf of West Virginia UniversityInventors: Brock A Lindsey, Justin E Markel, Ryan A Lacinski, Jabeen Noore
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Patent number: 12215086Abstract: This invention is directed to pyrrole, pyrazole, imidazole, triazole, and morpholine based selective androgen receptor degrader (SARD) compounds including heterocyclic anilide rings and their synthetic precursors. R-isomers, and non-hydroxylated and/or non-chiral propenamides, and pharmaceutical compositions and uses thereof in treating prostate cancer, advanced prostate cancer, castration resistant prostate cancer, triple negative breast cancer, other cancers expressing the androgen receptor, androgenic alopecia or other hyperandrogenic dermal diseases, Kennedy's disease, amyotrophic lateral sclerosis (ALS), abdominal aortic aneurysm (AAA), and uterine fibroids, and to methods for reducing the levels of androgen receptor-full length (AR-FL) including pathogenic to or resistance mutations, AR-splice variants (AR-SV), and pathogenic polyglutamine (polyQ) polymorphisms of AR in a subject.Type: GrantFiled: January 24, 2022Date of Patent: February 4, 2025Assignee: University of Tennessee Research FoundationInventors: Ramesh Narayanan, Duane D. Miller, Thamarai Ponnusamy, Dong-Jin Hwang, Yali He
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Patent number: 12217742Abstract: Embodiments are disclosed for generating full-band audio from narrowband audio using a GAN-based audio super resolution model. A method of generating full-band audio may include receiving narrow-band input audio data, upsampling the narrow-band input audio data to generate upsampled audio data, providing the upsampled audio data to an audio super resolution model, the audio super resolution model trained to perform bandwidth expansion from narrow-band to wide-band, and returning wide-band output audio data corresponding to the narrow-band input audio data.Type: GrantFiled: November 23, 2021Date of Patent: February 4, 2025Assignees: Adobe Inc., The Trustees of Princeton UniversityInventors: Zeyu Jin, Jiaqi Su, Adam Finkelstein
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Patent number: 12214006Abstract: Provided are a traditional Chinese medicine ointment for preventing and treating mastitis in dairy cows and a preparation method thereof, belonging to the technical field of veterinary traditional Chinese medicines. The traditional Chinese medicine ointment includes raw materials in parts by mass: 20-30 parts of dandelion, 20-30 parts of herba patriniae, 10-16 parts of Caulis Lonicerae Japonicae, 0.5-1 part of borneol, 0.03-0.05 part of polypeptide, 40-50 parts of auxiliary emulsifier, 40-50 parts of liquid paraffin and 100-130 parts of white vaseline. An amino acid sequence of the polypeptide is: Phe Phe Arg Lys Val Leu Lys Leu Ile Arg Lys Ile Trp Arg (SEQ ID NO. 1). In the application, dandelion, herba patriniae, Caulis Lonicerae Japonicae and borneol 1 are mixed, and polypeptide is added at the same time to prepare ointment.Type: GrantFiled: September 14, 2023Date of Patent: February 4, 2025Assignee: Hunan University of Science and EngineeringInventors: Zongcheng Wang, Yuanfei Xu, Zuodong Qin, Zhenmin Cao, Xiaofang Luo, Chen Gui, Shuwen Wang, Asad Nawaz, Manting Li
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Patent number: 12214788Abstract: An apparatus for controlling an autonomous vehicle disclosure may include a processor and a memory configured to be operatively connected to the processor and to store at least one code performed in the processor, wherein the memory may store a code that, when executed by the processor, causes the processor to control the autonomous vehicle to travel on the basis of a distance from a preceding vehicle in a travel lane in which the autonomous vehicle travels or a preset speed, determine a risk level of a lane change on the basis of a speed of the autonomous vehicle, a speed of a side vehicle traveling in a target lane of a lane change, and a distance between the autonomous vehicle and the side vehicle upon occurrence of a lane change request, and perform longitudinal or lateral control for the lane change on the basis of the risk level.Type: GrantFiled: December 1, 2021Date of Patent: February 4, 2025Assignee: Kookmin University Industry Academy Cooperation FoundationInventors: Ki Hong Park, Tae Young Oh, Weon Il Son
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Patent number: 12218522Abstract: A wireless power transfer device is disclosed that includes at least a first coil layer and a second coil layer, each coil layer including two coil windings positioned adjacent to one another in a lateral direction; wherein the two coil windings in each corresponding coil layer are connected in series and are wound in the same rotational direction, and the first and second coil layers are stacked in layers on top of one another. The magnetic fields of the coil layers can interact with one another in a constructive manner such that the overall efficiency and power transmission of the wireless power transfer device can be enhanced.Type: GrantFiled: November 17, 2023Date of Patent: February 4, 2025Assignee: Tennessee Technological UniversityInventors: Muhammad E. Bima, Indranil Bhattacharya
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Patent number: 12214418Abstract: A device for improving quality of aluminum alloy horizontal continuous casting billet by applying ultrasonic treatment is provided, including an ultrasonic generator, an ultrasonic transducer, an amplitude transformer, a holding furnace, an ultrasonic probe and a traction device. The ultrasonic generator is electrically connected with the ultrasonic transducer; the ultrasonic transducer is threadedly connected with the ultrasonic probe through the amplitude transformer, and the ultrasonic probe is placed in the holding furnace; a communication opening is formed at a bottom of the holding furnace, and the traction device is installed at the communication opening; the holding furnace is further poured with metal liquid.Type: GrantFiled: March 19, 2024Date of Patent: February 4, 2025Assignees: Dalian University of Technology, NingBo Institute of Dalian University of TechnologyInventors: Bin Ya, Xingguo Zhang, Linggang Meng, Bingwen Zhou, Changzhi Shan, Yunfeng Liu
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Patent number: 12213934Abstract: An exoskeleton leg is wearable by a person. The exoskeleton includes a thigh link configured to move in unison with the thigh of the person, a shank link rotatably coupled to the thigh link and comprising at least one tooth, and a locking block coupled to the thigh link and comprising a locking face. Moreover, when the at least one tooth of the shank link contacts with the locking face, the shank link is prevented from flexion motion relative to the thigh link, but is allowed to extend relative to the thigh link.Type: GrantFiled: March 22, 2021Date of Patent: February 4, 2025Assignees: The Regents of the University of California, suitX, Inc.Inventors: Wayne Tung, Minerva V. Pillai, James Hatch, Homayoon Kazerooni, Theerapat Yangyuenthanasan, Yusuke Maruo, David Cuban
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Patent number: 12213894Abstract: A portable device, method and system are provided for automated, quantitative assessment of orbital compliance and soft tissue restriction with emphasis on applicability to orbital trauma and fracture management is provided.Type: GrantFiled: June 4, 2020Date of Patent: February 4, 2025Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Benjamin Peter Erickson, Henry Bair
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Patent number: 12217339Abstract: A method for increasing the confidence of a match between a test image and an image stored in a library database in which features are extracted from the test image and compared to features stored in the image database. If a match is determined, one or more transformations are performed on the test image to generate pose-altered images from which features are extracted and matched with pose-altered images in the database. The scores for the subsequent matchings can be aggregated to determine an overall probability of a match between the test image in an image in the library database.Type: GrantFiled: March 31, 2022Date of Patent: February 4, 2025Assignee: Carnegie Mellon UniversityInventors: Marios Savvides, Uzair Ahmed
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Patent number: 12219113Abstract: A method and apparatus with image correction is provided. A processor-implemented method includes generating, using a neural network model provided an input image, an illumination map including illumination values dependent on respective color casts by one or more illuminants individually affecting each pixel of the input image, and generating a white-adjusted image by removing at least a portion of the color casts from the input image using the generated illumination map.Type: GrantFiled: August 16, 2021Date of Patent: February 4, 2025Assignees: Samsung Electronics Co., Ltd., Industry-Academic Cooperation Foundation, Yonsei UniversityInventors: Nahyup Kang, Seon Joo Kim, DongYoung Kim, JinWoo Kim, Yeonkyung Lee, Byung In Yoo, Hyong Euk Lee
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Patent number: 12214078Abstract: Disclosed herein is a particle containing an inner liposomal vesicle (ILV) encapsulating a therapeutic agent; an outer liposomal vesicle (OLV) encapsulating the ILV; a membrane fusion-promoting agent; and a pH-altering agent. Also disclosed are methods of delivering a therapeutic agent to a subject comprising: a) providing a herein disclosed particle b) triggering ILV and OLV fusion; and c) releasing the therapeutic agent outside of the OLV. Also disclosed are methods for treating a disease in a subject in need thereof comprising: administering to a subject a herein disclosed particle. Also disclosed are methods to release insulin to an environment comprising increased glucose levels, the method comprising exposing to the environment a herein disclosed particle.Type: GrantFiled: July 13, 2022Date of Patent: February 4, 2025Assignee: North Carolina State UniversityInventors: Zhen Gu, Zhaowei Chen
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Patent number: 12215327Abstract: The present disclosure provides genetically modified host cells that produce a cannabinoid, a cannabinoid derivative, a cannabinoid precursor, or a cannabinoid precursor derivative. The present disclosure provides methods of synthesizing a cannabinoid, a cannabinoid derivative, a cannabinoid precursor, or a cannabinoid precursor derivative.Type: GrantFiled: November 14, 2022Date of Patent: February 4, 2025Assignee: The Regents of the University of CaliforniaInventors: Jay D. Keasling, Leo D'Espaux, Jeff Wong, Xiaozhou Luo, Michael Reiter, Charles Denby, Anna Lechner
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Patent number: 12214052Abstract: A fusion protein comprises a nanocage monomer; and an antibody or fragment thereof linked to the nanocage monomer, the antibody or fragment thereof comprising a first member of a binding pair; wherein a plurality of the fusion proteins self-assemble to form a nanocage in which a plurality of the antibodies or fragments thereof decorate the exterior surface of the nanocage, whereby the first member of the binding pair is exposed for interacting with a second member of a binding pair.Type: GrantFiled: August 3, 2018Date of Patent: February 4, 2025Assignees: The Hospital for Sick Children, The Governing Council of the University of TorontoInventors: Jean-Philippe Julien, Taylor Sicard, Anthony Semesi, Bebhinn Treanor, Tiantian Zhao, Edurne Rujas Diez
