Patents Assigned to University
  • Patent number: 12291732
    Abstract: Disclosed herein is a method for producing a sialylated N-glycosylated recombinant protein in periplasm of a recombinant Escherichia coli. The sialylated N-glycosylated recombinant protein is produced in the periplasm of a recombinant Escherichia coli strain W3110?nanKETA::Kan, and a sialylated oligosaccharide chain is Neu5Ac-?-2,6-Gal-?-1,4-GlcNAc-?-1,3-Gal-?-1,3-GlcNAc.
    Type: Grant
    Filed: June 3, 2021
    Date of Patent: May 6, 2025
    Assignee: Dalian University
    Inventors: Xuejun Hu, Yao Ruan, Ning Ding, Xin Fu, Jing Zhu
  • Patent number: 12290575
    Abstract: The present subject matter provides compounds, compositions, and methods for identifying, monitoring, treating, and removing diseased tissue. Compounds, compositions, and methods for identifying, monitoring, and detecting circulating fluids such as blood are also provided.
    Type: Grant
    Filed: July 10, 2023
    Date of Patent: May 6, 2025
    Assignees: University of Rhode Island Board of Trustees, Yale University
    Inventors: Yana K. Reshetnyak, Oleg A. Andreev, Donald M. Engelman
  • Patent number: 12290468
    Abstract: An ostomy appliance according to an embodiment of the present invention comprises: an attachment part attached to the skin of a user; a cover assembly part disposed on the top surface of the attachment part and continuously dispensing plastic film into which excrement flows; and a sealing part that is coupled to one side of the cover assembly part and thermally seals a portion of the dispensed plastic film.
    Type: Grant
    Filed: March 3, 2021
    Date of Patent: May 6, 2025
    Assignee: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
    Inventors: Kwangdae Hong, Jaeyoung Kim
  • Patent number: 12292444
    Abstract: Disclosed herein are methods and compositions comprising chimeric green fluorescent protein (GFP) molecules embedded with foreign molecules. Also disclosed are methods of treating a subject with chimeric GFP molecules embedded with foreign molecules. Further disclosed are methods of delivering a desired molecule to a cell, wherein said desired molecule is embedded within a chimeric GFP molecule.
    Type: Grant
    Filed: March 31, 2021
    Date of Patent: May 6, 2025
    Assignee: University of South Florida
    Inventors: Vladimir N. Uversky, Bogdan S. Melnik
  • Patent number: 12294868
    Abstract: A method of building an ad-hoc network of a wireless relay node and an ad-hoc network system are disclosed. The method includes verifying state information representing a relative distance and angle to a neighboring node capable of receiving data when each of relay nodes transmits the data, determining an action representing a change over time of each relay node, determining, based on an amount of change in a network throughput determined according to the state information and an amount of energy consumption according to the action, a reward corresponding to the action, and building a network including a source node, a destination node, and a plurality of relay nodes by generating, based on a reward of each of the relay nodes, a policy that allows a cumulative reward to be maximized.
    Type: Grant
    Filed: May 9, 2022
    Date of Patent: May 6, 2025
    Assignees: Ewha University—Industry Collaboration Foundation, Foundation of Soongsil University-Industry Cooperation
    Inventors: Hyunggon Park, Nayoung Kim, Minhae Kwon
  • Patent number: 12291738
    Abstract: The present disclosure is directed to methods and/or uses of oligonucleotide conjugates for assays and flow cytometry detections and related systems and/or kits. Certain methods are directed to a method for detecting one or more biological targets of a sample in a detection assay, comprising: providing a molecular probe, comprising a binding moiety and an oligonucleotide sequence, to a sample comprising one or more biological targets; binding the one or more biological targets with the binding moiety; providing a detectable component to the sample, wherein the detectable component comprises a signal generating moiety conjugated to an oligonucleotide sequence complementary to the oligonucleotide sequence of the molecular probe; hydridizing the oligonucleotide sequence of the target-bound molecular probe to the detectable component; and detecting a signal generated from the hydridized detectable component. Various other embodiments, applications etc. are disclosed herein.
    Type: Grant
    Filed: July 7, 2021
    Date of Patent: May 6, 2025
    Assignees: The University of Chicago, EMD Millipore Corporation
    Inventors: David A. Schwartz, Jimmy Williams, Xinfang Zhao, Chunfang Zhao, William B. Busa, Stephen J. Kron, Amy Catherine Flor
  • Patent number: 12290455
    Abstract: A semi-powered foot and ankle prosthesis (100) has a foot member (128) coupled to the ankle frame (112) and movable with respect to the ankle frame (112). A linear actuator (144) is coupled to and between the ankle frame (112) and the foot member (128) to move the foot member (128) with respect to the ankle frame (112). The linear actuator (144) has a drive motor (150). A locking mechanism (104) selectively engages the drive motor (150) to selectively lock movement of the drive motor (150) to resist a force on the foot member (128) from backdriving the linear actuator (144).
    Type: Grant
    Filed: August 7, 2024
    Date of Patent: May 6, 2025
    Assignee: University of Utah Research Foundation
    Inventors: Tommaso Lenzi, Lukas R. Gabert, Connelly Ray Buchanan, Samuel Westgard, Minh Tran
  • Patent number: 12290454
    Abstract: Certain embodiments are directed to mechanical devices for augmenting dexterous reach and sensing of a user. The devices can include a proximal portion configured to receive an appendage of a user; a distal portion configured to detect sensory information; an articulation positioned between the proximal and distal portion to provide for motion of the distal portion via manipulation of the proximal portion; wherein the distal portion comprising a sensing element and the proximal portion comprises a feedback element, the feedback element being connected to the sensing element providing for physical extension of sensory capabilities of the appendage.
    Type: Grant
    Filed: October 13, 2018
    Date of Patent: May 6, 2025
    Assignee: Board of Regents, The University of Texas System
    Inventors: Corinne Nawn, Carlyn Abbott, Caroline Campbell, Sarah Robinson, Robert Hood, Christian Wahrmund, Andrea Afanador
  • Patent number: 12294124
    Abstract: A method of monitoring operation of a reactor system includes causing a chemical reaction to occur within an assembly of the reactor system, and measuring a chemical composition of one or more reactants of the chemical reaction with spatial resolution at a plurality of points along a path within the assembly using a sensor system structured to implement distributed sensing. The sensor system includes an optical fiber sensing member provided at least partially within the assembly, wherein the optical fiber sensing member comprises a functionalized optical fiber based sensor device structured to exhibit a change in one or more optical properties in response to changes in the chemical composition of the one or more reactants.
    Type: Grant
    Filed: April 19, 2022
    Date of Patent: May 6, 2025
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Peng K. Chen, Jacob Lorenzi Poole, Paul R. Ohodnicki, Thomas D. Brown, Kirk R. Gerdes, Michael P. Buric
  • Patent number: 12294219
    Abstract: A microgrid system includes a synchronous generator configured to convert mechanical power into electric power, an energy storage system configured to store and supply electric power, a controller configured to control operation of the energy storage system; and a point of common coupling bus connecting the synchronous generator and the battery energy storage system, wherein a controller parameter of the controller is determined based on a level of a disturbance using a trained artificial neural network in response to occurrence of the disturbance in the synchronous generator.
    Type: Grant
    Filed: March 12, 2021
    Date of Patent: May 6, 2025
    Assignees: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS, King Abdullah City for Atomic & Renewable Energy (K.A. CARE)
    Inventors: Jaber Ali Alshehri, Muhammad Khalid, Ahmed Hussain Alzahrani
  • Patent number: 12295232
    Abstract: An electronic device includes: a display layer in which an active area and a peripheral area adjacent to the active area are defined, the display layer including a common electrode, a sensor layer disposed on the display layer and including a plurality of sensing electrodes and an antenna pattern, and a cover layer spaced apart from the sensor layer with the display layer therebetween, the cover layer having a conductivity. The peripheral area includes a first area and a second area spaced apart from the active area with the first area therebetween, and the common electrode is disposed in the active area and the first area and is spaced apart from the second area. When viewed in a plan view, a portion of the antenna pattern does not overlap the common electrode and overlaps the cover layer.
    Type: Grant
    Filed: August 31, 2021
    Date of Patent: May 6, 2025
    Assignees: SAMSUNG DISPLAY CO., LTD., SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
    Inventors: Jungsuek Oh, Jae-Kyoung Kim, Seongryong Lee, Byeongjin Kim, Jeongtaek Oh
  • Patent number: 12291497
    Abstract: Provided herein is 3,3,3?,3?-tetramethyl-1,1?-spirobiindane-7,7?-diol, which is a compound represented by formula I, or an enantiomer or a raceme thereof. The is prepared with a 3,3,3?,3?-tetramethyl-1,1?-spirobiindane-7,7?-diol 3,3,3?,3?-tetramethyl-1,1?-spirobiindane-7,7?-dicarbaldehyde derivative as a starting material through a Baeyer-Villiger oxidation rearrangement reaction and an alkaline hydrolysis reaction. The 3,3,3?,3?-tetramethyl-1,1?-spirobiindane-7,7?-diol comprises two gem-dimethyl groups and is a key intermediate for preparing corresponding 3,3,3?,3?-tetramethyl-1,1?-spirobiindane-based monophosphine ligands, such as phosphonite ligands, phosphite ligands, phosphoramidite ester ligands, phosphoric acid and phsophonamidate. The 3,3,3?,3?-tetramethyl-1,1?-spirobiindane-7,7?-diol skeleton provided herein could be used in chemical industry and has economic practicality and industrial application prospects.
    Type: Grant
    Filed: March 22, 2022
    Date of Patent: May 6, 2025
    Assignee: ZHEJIANG UNIVERSITY
    Inventors: Xufeng Lin, Huanyu Shan, Qiaoxia Zhou
  • Patent number: 12290366
    Abstract: Wearable uroflowmetry systems having wearable uroflowmeters are disclosed. A disclosed example uroflowmetry system comprises a wearable uroflowmeter including: a funnel portion having an end configured to secure the funnel portion against a person, an outlet opposite the end, and a funnel configured to capture urine excreted by the person when the end is secured against the person, and to direct the captured urine into the outlet; a fluid passage portion having an opening configured to receive the urine from the outlet of the funnel portion, and a fluid channel to pass the received urine along a length of the fluid passage portion; and a measuring portion having a sensor in the fluid channel configured to collect one or more measurements of the urine as the urine passes the sensor, the measurements representative of at least one of a property of the urine, or a flow characteristic of the urine.
    Type: Grant
    Filed: October 23, 2020
    Date of Patent: May 6, 2025
    Assignees: THE REGENTS OF THE UNIVERSITY OF MICHIGAN, THE PROCTER & GAMBLE COMPANY
    Inventors: Ali Attari, James A. Ashton-Miller, John O. Delancey, Mark A. Burns, Tana Marie Kirkbride, Edward Paul Carlin, Alexzandra Joan Ramachandran, Carol A. Day
  • Patent number: 12291584
    Abstract: The present invention provides certain polymeric materials, precursors thereof as well as the preparation and uses thereof.
    Type: Grant
    Filed: May 4, 2023
    Date of Patent: May 6, 2025
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA
    Inventors: Dong-Chul Pyun, Robert A. Norwood, Roland Himmelhuber, Tristan Stephen Kleine, Liliana Ruiz Diaz, Laura E. Anderson
  • Patent number: 12291452
    Abstract: A method for producing hydrogen gas is disclosed. The method includes providing kerogen; providing hydrogen; introducing the kerogen and hydrogen into a reaction chamber wherein the reaction chamber is operated at an operating temperature between about 455° C. and 510° C.; and removing a gas stream comprising hydrogen.
    Type: Grant
    Filed: April 30, 2024
    Date of Patent: May 6, 2025
    Assignees: SAUDI ARABIAN OIL COMPANY, KING FAHD UNIVERSITY OF PETROLEUM & MINERALS
    Inventors: Ahmed Zarzor Hussien Yaseri, Pramod Dhanaji Patil, Israa Salem Ali Abu Mahfouz, Bidoor Alsaif
  • Patent number: 12294536
    Abstract: Disclosed is a method of obfuscating a Controller Area Network (CAN) message performed by a first computing device including a processor, the method including: obtaining a first index from a first input value corresponding to a first time point by using an index output algorithm; determining a first CAN ID of the first computing device corresponding to the first index based on a predetermined CAN ID table; and generating a first normal CAN message including the first CAN ID and first normal data.
    Type: Grant
    Filed: September 15, 2023
    Date of Patent: May 6, 2025
    Assignee: Korea University Research and Business Foundation
    Inventors: Huy Kang Kim, Hwejae Lee, Sangho Lee, Yeon Jae Kang, Daekwon Pi, Jae Woong Choi, Huiju Lee
  • Patent number: 12292893
    Abstract: A radiology workstation (24) includes at least one display component (30, 32); at least one user input device (28); and at least one microprocessor (26, 34) programmed to generate a contextual ranking of clinical codes for a context received via the at least one user input device (28) and to display information pertaining to the contextual ranking on the display component (30, 32) of the radiology workstation (24). The contextual ranking is computed by the microprocessor from (i) statistics of occurrences of the clinical codes in radiology reports contained in a radiology reports database (10) and satisfying the context and (ii) statistics of the clinical codes in problem lists contained in a problem lists database and satisfying the context.
    Type: Grant
    Filed: April 4, 2017
    Date of Patent: May 6, 2025
    Assignees: Koninklijke Philips N.V., The University of Chicago
    Inventors: Merlijn Sevenster, Paul Joseph Chang, Amir Mohammad Tahmasebi Maraghoosh
  • Patent number: 12292888
    Abstract: A fast and energy-efficient K-nearest neighbors search accelerator for a large-scale point cloud is provided. A nearest sub-voxel-selection (NSVS) framework that performs search based on a double-segmentation-voxel-structure (DSVS) search structure is constructed, and a K-nearest neighbors search algorithm for a large-scale point cloud map is implemented on a field programmable gate array (FPGA). The K-nearest neighbors search accelerator is configured for constructing the DSVS search structure, and searching for K-nearest neighbors based on the DSVS search structure. An experimental result on a KITTI dataset shows that the K-nearest neighbors search accelerator has a search speed 9.1 times faster than a state-of-the-art FPGA implementation. In addition, the K-nearest neighbors search accelerator also achieves an optimal energy efficiency, and the optimal energy efficiency is 11.5 times and 13.5 times higher than state-of-the-art FPGA and GPU implementations respectively.
    Type: Grant
    Filed: December 18, 2024
    Date of Patent: May 6, 2025
    Assignee: SHANGHAITECH UNIVERSITY
    Inventors: Yunhao Hu, Yajun Ha
  • Patent number: 12291533
    Abstract: Disclosed are new small molecules having a substituted pyrimidine or substituted fused pyrimidine core structure and the uses thereof for modulating glucocerebrosidase activity. Also disclosed are pharmaceutical compositions comprising the small molecules which may be administered in methods of treating diseases or disorders associated with glucocerebrosidase activity, including Gaucher's disease and neurological diseases and disorders such as genetic and sporadic synucleinopathies, including Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy associated with aberrant glucocerebrosidase activity. The small molecules may contain a fluorophore or may be conjugated to a fluorophore in order to prepare a fluorescent probe for use in high throughput screening methods to identify new modulators of glucocerebrosidase activity via fluorescence polarization.
    Type: Grant
    Filed: July 25, 2018
    Date of Patent: May 6, 2025
    Assignee: Northwestern University
    Inventors: Dimitri Krainc, Richard B. Silverman, Jianbin Zheng
  • Patent number: 12295252
    Abstract: A multiple cation-doped perovskite compound includes a perovskite represented by a formula of ABX3. A includes M1, M2, and M3. M1 represents a cation different from M2 and M3; M2 represents a cesium ion and M3 represents a formamidinium ion. B represents a divalent cation different from M1, M2, and M3. X includes at least two different halide ions. In addition, the perovskite compound is free from methylamine ion. A perovskite solar cell including the multiple cation-doped perovskite compound is also provided.
    Type: Grant
    Filed: July 21, 2023
    Date of Patent: May 6, 2025
    Assignee: MING CHI UNIVERSITY OF TECHNOLOGY
    Inventors: Yu-Ching Huang, Sheng-Wen Huang, Chia-Feng Li, Wei-Fang Su