Abstract: An integrated guidance and feedback control scheme for steering an underactuated vehicle through desired waypoints in three-dimensional space. The guidance and control algorithm takes as an input the desired trajectory for the translational motion that passes through the given waypoints, and autonomously generates the desired trajectory for the attitude based on the desired thrust direction to achieve the translational motion trajectory. A feedback control law is obtained to steer the underactuated vehicle towards the desired trajectories in translation and rotation.

Abstract: The present disclosure provides a copper nanowire composition. The copper nanowire composition includes copper nanowire having associated ligands with the structure HNR1R2, where R1 is hydrogen, alkyl group, or arylalkyl group, R2 is alkyl group or arylalkyl group, wherein the associated ligand has an amount of 100 wt % to 10000 wt % versus a weight of the copper nanowire.

Abstract: Disclosed are an offset calibration method and circuit applied to a comparator array. The offset calibration circuit includes a global calibration voltage generation module, integrators, comparators, a global logic control circuit, and local logic control circuits; an entire comparator array shares the single global calibration voltage generation module, and each of the comparators only needs to introduce an integrator circuit, such that a large calibration range and a small calibration step are achieved, a long calibration cycle and a large circuit area are required, and the requirements for a low area are satisfied. The offset calibration method provided by the present disclosure is similar to a binary search algorithm, which is adopted to search for the offset voltage, the calibration step of 1 2 N ? Vref can be realized by only N cycles, and short calibration time is thus realized.

Abstract: The present invention relates, in general, to a method of treating patients undergoing enzyme replacement therapy (ERT) or other therapy involving the administration of a proteinaceous therapeutic agent as well gene replacement therapy with non-viral or viral vectors, or other therapeutic modality or modalities, used alone or in combination, which involve the administration of exogenous substances for potential therapeutic benefit, including, but not limited to DNA vaccines, siRNA, splice-site switching oligomers (SSOs) as well as RNA-based nanoparticles (RNPs) and nanovaccines. The invention further relates to compounds and compositions suitable for use in such methods.

Abstract: Systems and methods are provided for enabling users to work with TimeML annotations and perform advanced temporal analysis, offering a comprehensive suite of features. Systems and methods of embodiments allow users to parse TimeML annotations, construct TimeML graphs, and execute the timeline extraction (TLEX) algorithm to effect complete timeline extraction. An algorithm can be incorporated for increasing connectivity in temporal graphs, which identifies graph disconnectivity and recommends links based on temporal reasoning, thereby enhancing the coherence of the graph representation. Also, a built-in validation algorithm can be included, ensuring compliance with TimeML annotation guidelines.

Abstract: A lightweight intrusion detection method includes obtaining a feature data set of the internet of vehicles and pre-processing data; dividing pre-processed data into an initial training set, an initial verification set and an initial test set according to a preset proportion, performing data balance on the initial training set to obtain a balanced training set, performing feature selection on the balanced training set, the initial verification set and the test set; obtaining a teacher model by training with the model training set and the model verification set; using the teacher model, the model training set and the model verification set for distillation training to obtain a student model; testing a size and complexity of the student model and the performance of the student model, and saving the student model that passes the test as a lightweight intrusion detection model; and deploying the lightweight intrusion detection model.

Abstract: Disclosed are a strain of Lactobacillus helveticus capable of removing multiple heavy metals and an application thereof in milk powder, where the strain is Lactobacillus helveticus KD-3, which is deposited in the China Center for Type Culture Collection on Apr. 6, 2023, with a deposit number of CCTCC NO: M2023479. The Lactobacillus helveticus KD-3 has a cadmium resistant gene czcD, a chromium resistant gene chrA and a lead resistant gene pbrT, and is capable of tolerating single and compound heavy metals (cadmium, chromium and lead). The Lactobacillus helveticus KD-3 of the present disclosure is used to prepare lyophilized bacterial powder.

Abstract: Methods of treating propionic acidemia (PA), methylmalonic acidemia (MMA) and fatty acid oxidation disorders are described. The methods include administering an anaplerotic agent that can directly enter the tricarboxylic acid cycle, such as a succinate derivative or pro-drug, for example trisuccinylglycerol (TSG). Methods of restoring tricarboxylic acid (TCA) cycle function in a cell deficient for propionyl-CoA carboxylase (PCC) or methylmalonyl-CoA mutase (MUT) by contacting the cell with a succinate derivative or pro-drug, such as TSG, are also described.

Abstract: A pipe connector for use in high temperature environments, such as those characteristics of molten salt reactors. The pipe connector can be used in any industry that uses pipe connectors, and in particular, can be used in a molten salt system including a reactor requiring a connection rated for a maximum of about 725° C. and about 15,000 psi. The pipe connector may comprise a pin, a seal ring, a retainer ring, a box, a locking nut, and a retaining nut.

Abstract: Systems and methods are disclosed for an electrical sensing, pacing, and ablation device comprising a bendable and stretchable balloon catheter and a bendable and stretchable first layer connected to or embedded in said balloon catheter, where the first layer has an electrode array with a plurality of electrodes. The is also a bendable and stretchable second layer connected to or embedded in the balloon catheter, and the second layer has a pressure sensor array with a plurality of pressure sensors.

Abstract: A computer system for intra-ear sensing and stimulating receives, health data, from an earbud sensor. The system repeatedly calculates an exponential moving average (EMA) of a moving window for the received health data. The system compares each calculated exponential moving average with a lower threshold value and an upper threshold value. The upper threshold value and the lower threshold value are determined based, at least in part, upon a saturation level associated within an amplifier performing the adaptive gain control. When the calculated exponential moving average is larger than the upper threshold, the system decreases a gain associated with the amplifier. When the calculated exponential moving average is smaller than the lower threshold, the system increases a gain associated with the amplifier.

Abstract: A method of building an ad-hoc network of a wireless relay node and an ad-hoc network system are disclosed. The method includes verifying state information representing a relative distance and angle to a neighboring node capable of receiving data when each of relay nodes transmits the data, determining an action representing a change over time of each relay node, determining, based on an amount of change in a network throughput determined according to the state information and an amount of energy consumption according to the action, a reward corresponding to the action, and building a network including a source node, a destination node, and a plurality of relay nodes by generating, based on a reward of each of the relay nodes, a policy that allows a cumulative reward to be maximized.

Abstract: A radiology workstation (24) includes at least one display component (30, 32); at least one user input device (28); and at least one microprocessor (26, 34) programmed to generate a contextual ranking of clinical codes for a context received via the at least one user input device (28) and to display information pertaining to the contextual ranking on the display component (30, 32) of the radiology workstation (24). The contextual ranking is computed by the microprocessor from (i) statistics of occurrences of the clinical codes in radiology reports contained in a radiology reports database (10) and satisfying the context and (ii) statistics of the clinical codes in problem lists contained in a problem lists database and satisfying the context.

Abstract: The present disclosure is directed to methods and/or uses of oligonucleotide conjugates for assays and flow cytometry detections and related systems and/or kits. Certain methods are directed to a method for detecting one or more biological targets of a sample in a detection assay, comprising: providing a molecular probe, comprising a binding moiety and an oligonucleotide sequence, to a sample comprising one or more biological targets; binding the one or more biological targets with the binding moiety; providing a detectable component to the sample, wherein the detectable component comprises a signal generating moiety conjugated to an oligonucleotide sequence complementary to the oligonucleotide sequence of the molecular probe; hydridizing the oligonucleotide sequence of the target-bound molecular probe to the detectable component; and detecting a signal generated from the hydridized detectable component. Various other embodiments, applications etc. are disclosed herein.

Abstract: A method of monitoring operation of a reactor system includes causing a chemical reaction to occur within an assembly of the reactor system, and measuring a chemical composition of one or more reactants of the chemical reaction with spatial resolution at a plurality of points along a path within the assembly using a sensor system structured to implement distributed sensing. The sensor system includes an optical fiber sensing member provided at least partially within the assembly, wherein the optical fiber sensing member comprises a functionalized optical fiber based sensor device structured to exhibit a change in one or more optical properties in response to changes in the chemical composition of the one or more reactants.

Abstract: Disclosed herein are methods and compositions comprising chimeric green fluorescent protein (GFP) molecules embedded with foreign molecules. Also disclosed are methods of treating a subject with chimeric GFP molecules embedded with foreign molecules. Further disclosed are methods of delivering a desired molecule to a cell, wherein said desired molecule is embedded within a chimeric GFP molecule.

Abstract: A multiple cation-doped perovskite compound includes a perovskite represented by a formula of ABX3. A includes M1, M2, and M3. M1 represents a cation different from M2 and M3; M2 represents a cesium ion and M3 represents a formamidinium ion. B represents a divalent cation different from M1, M2, and M3. X includes at least two different halide ions. In addition, the perovskite compound is free from methylamine ion. A perovskite solar cell including the multiple cation-doped perovskite compound is also provided.

Abstract: A semi-powered foot and ankle prosthesis (100) has a foot member (128) coupled to the ankle frame (112) and movable with respect to the ankle frame (112). A linear actuator (144) is coupled to and between the ankle frame (112) and the foot member (128) to move the foot member (128) with respect to the ankle frame (112). The linear actuator (144) has a drive motor (150). A locking mechanism (104) selectively engages the drive motor (150) to selectively lock movement of the drive motor (150) to resist a force on the foot member (128) from backdriving the linear actuator (144).

Abstract: Provided are an apparatus for diagnosing a disease and a method for diagnosing same. The apparatus includes a pump for pumping respiratory gas, a first pre-treatment portion connected to the pump and removing moisture and bad breath in the respiratory gas, and a volatile organic compound detector connected between the first pre-treatment portion and the pump and detecting volatile organic compounds in the respiratory gas.

Abstract: An insulated heating-unit cover having an opening to permit air to circulate around the heating-source when a vent disposed at the top of the cover is opened, allowing heat into a space. The cover can include a heating-unit temperature sensor disposed within a space covered by the cover and a controller in wireless communication with a space temperature sensor located at a distance away from the heating-unit. The controller can be configured to operate an actuator such that the vent is open when the space temperature sensor indicates that the ambient temperature is below a set point temperature and such that the vent is closed when the ambient temperature is greater than the set point temperature. The controller can communicate with a plurality of other similar controllers and a central server to effect changes in the output of a central heating source coupled to a plurality of individual heating-units.