Abstract: A compound of formula (I), wherein R1 is an optionally substituted aryl or an optionally substituted heteroaryl, R2 is an optionally substituted aryl or an optionally substituted heteroaryl, and R3 is an optionally substituted alkylamino, an optionally substituted cycloalkylamino, an optionally substituted arylamino, an optionally substituted heterocyclylamino, an optionally substituted heterocyclyl, and an optionally substituted dialkylamino. A pharmaceutical composition which includes the compound of formula (I) and a pharmaceutically acceptable carrier and/or excipient. A method of treating colorectal cancer in a subject, whereby a therapeutically effective amount of the compound of formula (I) is administered to the subject.

Abstract: The present invention relates to a wearable device using a flexible non-powered variable impedance mechanism, wherein the device can induce a user to have a correct posture during a squat exercise or lifting work, and can assist the user's muscular strength. According to the present invention, an angle between a (1-1)th lower string and a (1-2)th lower string and an angle between a (2-1)th lower string and a (2-2)th lower string change according to a knee angle depending on the user's posture, whereby an impedance mechanism that the user feels through the body changes.

Abstract: A device to change the temperature of a localized volume of material. A workable device includes at least one heat transfer mechanism having an external surface for direct contact with an exposed surface of the material. A working fluid is directed by input and output conduits to contact an internal surface of the heat transfer mechanism. The heat transfer mechanism exchanges heat between the working fluid and the material. Temperature of the working fluid may be regulated by a thermal system disposed at a remote location. An optional temperature sensing element may monitor a local temperature of the heat transfer mechanism or otherwise infer a temperature of a portion of the material. Sometimes, a device includes a cooperating anchoring arrangement to facilitate holding the heat transfer mechanism in a desired spot. Certain devices may be plastically deformed to a desired device shape.

Abstract: The present disclosure relates to a realtime urban traffic status monitoring method based on privacy-preserving compressive sensing, including the following steps: step S1: dividing vehicle data under privacy preserving into two parts, and sending the two parts to two different road side units (RSU) for preprocessing; step S2: outsourcing, by the two different RSUs, preprocessed vehicle data to two cloud platforms (CP) respectively, and designing a data encryption execution protocol based on a finally expected operation result and interactive operation between the two CPs, to encrypt the data; and step S3: receiving, by a navigation service provider (NSP), encrypted data from the CPs, decrypting the received encrypted data, and estimating an urban traffic status by using a compressive sensing technology.

Abstract: A scalpel that safely and efficiently removes excess dental composite from the surfaces of teeth. A method for removing excess dental composite from a dental surface using this dental scalpel.

Abstract: Examples of systems and methods described herein may provide saliency-based video compression. A saliency map associated with a video may be generated and/or provided. A tile configuration may be selected for the video and quality settings assigned to each tile in accordance with the saliency map. The video may then be compressed (e.g., encoded) in tiles in accordance with the quality settings. Compressed videos may be stored together with saliency metadata, facilitating storage management and/or re-compression.

Abstract: The present invention provides a longitudinally split immature tiller separated from a rhizome (LSITR), a cluster of multiple in vitro shoots (CMIT), a cluster of stem segments containing shoot primordia (CSSSP) and an in vitro tiller of Miscanthus x giganteus (Giant Miscanthus), and their uses in propagating Miscanthus x giganteus (Giant Miscanthus).

Abstract: Disclosed are recombinant phages that infect and kill bacterial hosts in response to user-defined inputs. The components that encode the user-defined inputs can be combined, such that multiple inputs are maintained on a single recombinant phage, enabling precise control over the targeting strategy. The phages can be engineered to kill a specific bacterial species or multiple species simultaneously. Recombinant phages can also be engineered to harbor fluorescent and bioluminescent reporter genes that enable them to be used for tracking, detection, and in biosensing applications. Recombinant phages can also be used to lyse bacterial cells that produce recombinant proteins, as a rapid method to enable extraction and high-level purification of potentially valuable and/or industrially important proteins.

Abstract: Provided is a semiconductor material having improved oxidation resistance. The semiconductor material has a single crystal represented by the following composition formula: Mg2Sn.Zna??Composition formula: in which, a is a Zn content of from 0.05 to 1 at % relative to Mg2Sn.

Abstract: A distributed type traffic line tracing apparatus of the present disclosure is personally installed in a residence of a tracing target person, to automatically verify whether a traffic line of the tracing target person coincides with a traffic line of a confirmed person and automatically report a result to a disease management authority only when the traffic lines coincide with each other in an emergency situation such as an infectious disease pandemic, so that a quarantining target person is discovered and found early while protecting a privacy of an individual much more when compared to a centralized type, thereby rapidly establishing an infectious disease management system for patients with suspected diseases and efficiently managing the patients from the spread of infectious diseases.

Abstract: A light conversion device includes a light-emitting unit, a photoelectric conversion unit, and an electroconductive bonding layer. Each of the light-emitting unit and the photoelectric conversion unit includes a first-type region and a second-type region opposite to the first-type region. The electroconductive bonding layer is disposed between the light-emitting unit and the photoelectric conversion unit for connecting the photoelectric conversion unit with the light-emitting unit. When the light conversion device is operated to receive a bias and an external light, the light-emitting unit generates a modulated light having a frequency different from that of the external light.

Abstract: A method of correcting gravity-induced error in quantum cryptography system, which is capable of improving accuracy when an optical cable is not installed and photons are transmitted through an artificial satellite, is disclosed. The method performed by an electronic device, comprises receiving a distance (r) to a satellite that receives polarized photon from a sender and transmits the polarized photon to a receiver, receiving an angular momentum per unit mass of the satellite (lobs), and calculating a rotation amount of the polarized photon, which is induced by a warp of space due to gravity by using the distance to the satellite and the angular momentum per unit mass of the satellite (lobs). The rotation 2? of the polarized photon is calculated by the following equation, sin ? ? ? ? ( r ) ? - l obs rr s ? 1 - r s r , wherein ‘rs’ is the Schwarzschild radius of the Earth.

Abstract: A method for a direct current (DC) islanding detection based on positive feedback of a bus voltage at a specific frequency, essentially including three steps: extraction of a specific frequency component of the bus voltage, injection of a disturbance component of the specific frequency, and determination of DC islanding. The extraction of the specific frequency component of the bus voltage and the injection of the disturbance component of the specific frequency constitute a positive feedback mechanism in a power management unit control loop. In a grid-connected mode of a DC grid, the positive feedback mechanism fails due to a control action of a voltage management unit on a bus, and the bus voltage remains stable. In an islanding mode of the DC grid, under an action of the positive feedback mechanism, the power management unit allows the bus voltage to generate a self-excited oscillation at the specific frequency.

Abstract: Disclosed is a nonincendive electrolyte for lithium secondary battery, the electrolyte using an organic solvent mixture including a first solvent containing fluorine and sulfur, a second solvent that is a linear carbonate-based compound containing fluorine, a third solvent that is a linear ester-based compound containing fluorine, and a fourth solvent that is a cyclic carbonate-based compound. Thus, the electrolyte is nonflammable or flame-retardant, thereby preventing a lithium secondary battery from catching on fire or exploding. That is, the electrolyte greatly improves the safety of a lithium secondary battery, allows the high voltage charge of a lithium secondary battery, and prevents the degradation of battery performance of a lithium secondary battery. In addition, a lithium secondary battery including the electrolyte is disclosed.

Abstract: Provided are compositions and methods for determining an imprinting status of a gene subject to parent-of-origin, monoalleleic expression in a subject, and for using the information derived therefrom to detect a presence of and/or a susceptibility to a medical condition associated with monoallelic expression in a subject, predict a susceptibility to future development of a medical condition prior to the onset of any symptoms, monitor the development of such a medical condition and/or the effectiveness of a treatment, and for treating such a medical condition. In some embodiments, a composition for use in the disclosed methods is nucleic acid array, which in some embodiments can include one or more interrogatable nucleotide molecules, wherein the interrogatable nucleotide molecules are designed to allow identification of the DNA methylation status of one or more imprint control regions (ICRs) that regulate one or more genes subject to monoalleleic expression in subjects.

Abstract: Systems and methods for heart stimulation in accordance with embodiments of the invention are illustrated.

Abstract: An apparatus measures the transverse profile of vectorial optical field beams, including both the phase and the polarization spatial profile. The apparatus contains a polarization separation module, a weak perturbation module, and a detection module. Characterizing the transverse profile of vector fields provides an optical metrology tool for both fundamental studies of vectorial optical fields and a wide spectrum of applications, including microscopy, surveillance, imaging, communication, material processing, and laser trapping.

Abstract: In some embodiments, an augmented reality system is provided. The augmented reality system is configured to detect real-world objects, create software objects that represent the real-world objects, receive requests from applications to present virtual objects at locations associated with the real-world objects, and to present the virtual objects. In some embodiments, an operating system of the augmented reality system is configured to resolve conflicts between requests from multiple applications. In some embodiments, the operating system of the augmented reality system is configured to provide information to applications to allow the applications to avoid or resolve conflicts amongst themselves.

Abstract: Provided are cannabinoid-loaded formulations, as well as processes for their preparation.

Abstract: The present invention provides a method for producing a pluripotent stem cell released from resistance to differentiation into mesendodermal lineage, including subjecting a pluripotent stem cell to a treatment for activating an integrin ?1-?-catenin signal transduction pathway (excluding contacting the pluripotent stem cell with laminin 421 or a fragment thereof and/or laminin 121 or a fragment thereof), and the like.