Abstract: The invention provides a novel class of materials that possess triplet-triplet annihilation upconversion, compositions and methods of preparation and use thereof. The invention also relates to use of such materials and nanoparticles, for example, in stimulus-responsive, in situ delivery of biologically active agents.

Abstract: A system for analyzing tissue includes a platform and an optical sensing unit coupled to the platform. The optical sensing unit has a detector and a plurality of light sources surrounding and electrically isolated from the detector. The optical sensing units obtain optical data for tissue analysis.

Abstract: Methods are provided for targeting pediatric brain tumor cells for depletion.

Abstract: Disclosed are enantiomerically pure cyclopentane-based compounds that are prepared by a multiple-step synthesis process. The disclosed compounds have been designed to inhibit gamma-aminobutyric acid-amino transferase (GABA-AT) activity and ornithine aminotransferase (OAT) activity. Some of the enantiomerically pure compounds inhibit OAT activity more potently than the racemic compound. The disclosed compounds may be used to selectively inhibit OAT activity, for example, to treat hepatocellular carcinoma and/or used to selected inhibit GABA-AT activity, for example, to treat neurological diseases and disorders.

Abstract: Provided are methods, apparatuses, and systems for tracking a pupil of an eye of a user with degraded iris authentication accuracy. In certain examples, an eye tracking device includes a camera adapted to capture an eye image of at least one eye of a user. The eye tracking device further includes an image processor adapted to defocus the eye image in order to generate a defocused eye image. The defocused eye image comprises reduced iris authentication accuracy. The eye tracking device further includes a tracking processor configured to detect a pupil in the defocused eye image and determine a gaze direction of the user based at least in part on one or more of the defocused eye image and the pupil.

Abstract: A radiative cooling substrate and a manufacturing method of the radiative cooling substrate are provided. The radiative cooling substrate includes a metallic substrate and a chitosan layer disposed on the metallic substrate with a thickness of 0.5 ?m to 10 ?m. The chitosan layer emits radiation within a waveband between 8 ?m and 13 ?m.

Abstract: Composite molded pulp products prepared from fruit or vegetable-based pomace, fibrous paper-based materials, and cellulose nanofiber and methods for preparing the same are provided.

Abstract: A system includes a projection device configured to project images onto a receiver surface of a viewing device. The viewing device includes a screen having the receiver surface and a viewing surface opposite the receiver surface. The screen is configured to permit transmission of the images through the screen, from the receiver surface, to the viewing surface such that the images are viewable on the viewing surface. The viewing device also includes a focusing lens configured to focus the images for a user when wearing the viewing device. Further, the system includes a tracking system configured to determine a location and orientation of the receiver surface of the viewing device. The projection device is configured to adjust image properties of the images based at least in part on the determined location and orientation of the receiver surface.

Abstract: The invention relates to methods and kits for DNA The method comprises a) contacting the sample with a plurality of metal nanoparticles functionalised with one or more RNA probes; b) forming a heteroduplex between the target DNA and RNA probe on an RNA-functionalised metal nanoparticle; c) contacting the heteroduplex of target DNA and RNA probe on the RNA-functionalised metal nanoparticle with an enzyme that cleaves RNA in a DNA-RNA heteroduplex thereby releasing the target DNA; d) repeating steps (b) and (c) until all, or substantially all, of the RNA probes on the plurality of RNA-functionalised metal nanoparticles have been cleaved from the metal nanoparticles; and e) aggregating the metal nanoparticles from which all, or substantially all, of the RNA probes have been cleaved, thereby indicating the presence of the target DNA.

Abstract: The present application relates to compositions comprising an iodinated contrast agent and indocyanine green co-encapsulated inside a liposomal carrier, various uses thereof as well as methods for their preparation.

Abstract: The subject matter of this specification can be embodied in, among other things, a method for operating a hydraulic free piston engine includes receiving, at an engine controller for a hydraulic free piston engine, an energy parameter that is representative of an amount of fluid energy to be output by the engine, and a measured fluid pressure value of a fluid load of the engine, determining a piston trajectory of a piston within a hydraulic chamber of the engine, determining a fuel volume value and a servo valve actuation parameter, based on the energy parameter and the measured fluid pressure value, providing a fuel control signal to a fuel control device of the engine based on the fuel volume value, and providing, based on the servo valve actuation parameter and the piston trajectory, a servo valve control signal to a servo valve.

Abstract: Triazole conjugated urea-based and thiourea-based scaffolds that have high binding affinity to PSMA are disclosed. These scaffolds can be radiolabeled and used to image cells and tumors that express PSMA. Methods of synthesizing radiofluorinated triazole conjugated urea-based and thiourea-based scaffolds also are disclosed.

Abstract: Disclosed are variants of ACE2, pharmaceutical compositions comprising the variants of ACE2, and treatment methods for reducing Angiotensin II (1-8) plasma levels and/or increasing Angiotensin (1-7) plasma levels in a subject in need thereof. The disclosed variants of ACE2 may include polypeptide fragments of ACE2 having ACE2 activity for converting AngII (1-8) to Ang(1-7). Suitable subjects suitable for the disclosed methods of treatment may include subjects having or at risk for developing diabetic and non-diabetic chronic kidney disease, acute renal failure and its prevention, chronic kidney disease, severe hypertension, scleroderma and its skin, pulmonary, kidney and hypertensive complications, malignant hypertension, renovascular hypertension secondary to renal artery stenosis, idiopathic pulmonary fibrosis, liver fibrosis such as in liver cirrhosis patients, an aortic aneurysm, cardiac fibrosis and remodeling, left ventricular hypertrophy, and an acute stroke.

Abstract: A method includes classifying low-resolution pixels of a low-resolution satellite image of a geographic area to form an initial classification map and selecting at least one physically-consistent classification map of the low-resolution pixels based on the initial classification map. A water level associated with at least one of the physically-consistent classification maps is then used to identify a set of high-resolution pixels representing a perimeter of water in the geographic area.

Abstract: A size and/or shape specific 3D-beam modulation filter and a size and/or shape specific immobilizer are provided for cone-beam breast computed tomography (bCT). The immobilizer places the breast on an optimal position in the field of view of the scanner system and the 3D-beam modulation filter modulates the incident x-ray beam in the cone-angle (i.e. z-axis of the detector panel) and fan angle (i.e. x-axis of the detector panel) directions in order to improve equalization of the photon fluence incident upon the detector panel and reduce unnecessary radiation dose that the breast receives. Both the immobilizer and the 3D-beam modulation filter are selected among a plurality of alternatives based on the specific shape, size and/or shape or size of the person's breast.

Abstract: Disclosed herein are methods of detecting microbial infection in mammalian subjects comprising treatment of a sample and detection of galactofuranose (galF)-containing antigenic components utilizing monoclonal antibodies. The methods disclosed provide for pretreatment of biological samples, such as urine samples, to maximize detection of galF antigens and improvement of sensitivity of galF antigen detection assays. The methods include minimizing intelectin-1 binding to galF antigens and improvement of monoclonal antibody binding. The detection methods are useful for identifying the presence of microbial antigens related to bacterial, fungal, and parasitic pathogens, including Streptococcus pneumoniae, Aspergillus species, Fusarium species, Coccidioides species, Cryptococcus species, Histoplasma species, and Leishmania species.

Abstract: A wireless communication method and device include: a transmitting device dividing a to-be-transmitted signal into a plurality of packets by using a pre-agreed key; acquiring a preset equivocation threshold; according to the equivocation threshold, determining a power parameter adjustment factor for each of the packets; for each of the packets, performing power adjustment on a signal of the packet according to a power parameter adjustment factor of the packet; and transmitting the to-be-transmitted signal after power adjustment. After receiving the signal, the receiving device groups the signals according to the pre-agreed key, and calculates the power of each packet; determines a test statistic according to the power of each packet, and determines the test statistic whether the quantity is greater than or equal to a preset statistic threshold. If so, it determines that the signal is a tag signal, and if not, that it is a regular signal.

Abstract: A method for encoding image signal, according to the present invention, can: encode a partial block coefficient flag indicating whether a coefficient of a current partial block is a non-zero coefficient; encode a first flag indicating whether an absolute value of the coefficient is greater than 1, encode a second flag indicating whether the absolute value of the coefficient is greater than 2; encode the residual coefficients, which have not been encoded, on the basis of the first flag or the second flag in the current partial block; and encode a code for the coefficient of the current partial block.

Abstract: Various methods for evaluating hemostatic effect and various blood coagulation initiation reagents were studied to construct a method for evaluating blood coagulation reaction mediated by a substance having an activity of substituting for coagulation factor VIII (FVIII). As a result, it was discovered that by using a coagulation initiation reagent containing activated coagulation factor XI (FXIa) and phospholipids, the effect of a substance having an activity of substituting for coagulation factor VIII (FVIII) on blood coagulation reaction can be evaluated using the amount of thrombin generated in the blood sample as an indicator.