Abstract: The present disclosure provides a method for identifying a carrier motion mode based on a time-domain differential characteristic. Firstly, a difference operation is performed on data to obtain a difference sequence, and then sign, progressive multiplication, and accumulation operations are performed on the difference sequence, and finally thresholds are set to determine an accumulation sequence, so as to obtain a carrier motion mode. All operations involved in this method are performed in time domain, and the method has the advantages of simple algorithm, good real-time performance, accurate determination, and strong robustness.

Abstract: A sensor including a layer of amorphous selenium (a-Se) and at least one charge blocking layer is formed by depositing the charge blocking layer over a substrate prior to depositing the amorphous selenium, enabling the charge blocking layer to be formed at elevated temperatures. Such process is not limited by the crystallization temperature of a-Se, resulting in the formation of an efficient charge blocking layer, which enables improved signal amplification of the resulting device. The sensor can be fabricated by forming first and second amorphous selenium layers over separate substrates, and then fusing the a-Se layers at a relatively low temperature.

Abstract: The present disclosure provides biomarkers for the identification of prostate cancer and methods of use. The present disclosure also provide biomarkers that can be used for determining risk of developing prostate cancer, aggressiveness of prostate cancer and survival rate for subpopulations of African American males or non-Hispanic white males.

Abstract: An aminated siliceous adsorbent, which is the reaction product of dried acidified rice husk ash having disordered mesopores and an amino silane, wherein amine functional groups are present on an external surface and within the mesopores of the dried acidified rice husk ash, and wherein the aminated siliceous adsorbent has a carbon content of 24 to 30 wt. %, based on a total weight of the aminated siliceous adsorbent. A method of making the aminated siliceous adsorbent and a method of capturing CO2 from a gas mixture with the aminated siliceous adsorbent.

Abstract: Disclosed are methods and pharmaceutical compositions for treating and inhibiting conical vascularization including conical vascularization associated with viral infection, chemical injury, autoimmune conditions, and post-corneal transplantation or in subjects having a PAX6 mutation associated with conical vascularization. The methods and pharmaceutical compositions are utilized in administering treatment that results in increased concentration of FOXC1 in a subject's cornea in order to treat or inhibit corneal vascularization.

Abstract: Methods and compositions for modulating repeat non-ATG protein (RAN protein) translation are provided. In some aspects, the disclosure relates to methods for treating a subject having a disease associated with RAN protein translation by administering the subject a modulator of eIF3 or an eIF3 subunit, or an antibody that bind to a RAN protein.

Abstract: Systems and methods implement of high-speed delay scanning for spectroscopic SRS imaging characterized by scanning a first pulsed beam across a stepwise reflective surface (such as a stepwise mirror or a reflective blazed grating) in a Littrow configuration to generate near continuous temporal delays relative to a second pulsed beam. Systems and methods also implement deep learning techniques for image restoration of spectroscopic SRS images using a trained encoder-decoder convolution neural network (CNN) which in some embodiments may be designed as a spatial-spectral residual net (SS-ResNet) characterized by two parallel filters including a first convolution filter on the spatial domain and a second convolution filter on the spectral domain.

Abstract: Methods and compositions for treating sinusitis in a subject are provided. The methods include administering to the subject an effective amount of a composition that stimulates growth or activity of a genus of bacteria that is decreased relative to a control subject not having sinusitis and/or inhibiting growth or activity of a genus of bacteria that is increased relative to the control subject.

Abstract: Provided are compositions and methods for using the same. In some embodiments, the compositions include an EPELN encapsulating and/or having associated therewith an active agent and a plasma membrane derived from a tumor and/or cancer cell coating the EPELN. In some embodiments, the active agent is a therapeutic agent or an immune response modifier, and in some embodiments the plasma membrane has one or more tumor-associated and/or cancer-associated antigens. Also provided are methods for using the compositions for treating tumors and/or cancers, inducing anti-tumor and/or anti-cancer immune responses, activating antigen-presenting cells, targeting CD1 lc dendritic cells, and preventing or reducing metastasis.

Abstract: The disclosure relates, in some aspects, to adeno-associated vims capsid proteins isolated from an in vivo library and recombinant adeno-associated viruses (rAAVs) comprising the same. In some aspects, the disclosure relates to isolated nucleic acids encoding AAV capsid proteins isolated from an in vivo library. In some embodiments, rAAVs and compositions described by the disclosure are useful for delivery of one or more transgenes to the muscle-tissue of a subject.

Abstract: An information collection system includes: a side-channel information processing unit that derives load information to estimate an impact on the availability of a target machine for active scanning by using side-channel data; an allow list generation unit that generates an allow list including a scan timing and a scan range in which the availability is not affected, the allow list generation unit generating the allow list based on the load information; and an allow list storage unit that stores the allow list. An active scan of the target machine is executed by referencing the allow list stored in the allow list storage unit to collect asset information of the target machine.

Abstract: Described herein are methods and devices that allow the generation of [F-18]triflyl fluoride and other [F-18] sulfonyl fluorides (such as [F-18]tosyl fluoride) in a manner that is suitable for radiosynthesis of F-18 labeled radiopharmaceuticals using currently available synthesis modules.

Abstract: The present invention provides new compounds and compositions thereof that release carbon monoxide for the treatment of medical disorders that are responsive to carbon monoxide, for example, inflammatory, pain, and dermatological disorders.

Abstract: The disclosure provides for immunomodulatory oligosaccharides, and uses thereof.

Abstract: The present invention includes methods for detecting and reducing or inhibiting ischemic stroke in a mammal, the method comprising: (a) selecting microRNAs to downregulate selected from the group consisting of hsa-miR-96-5p, hsa-miR-99a-5p, hsa-miR-122-5p, hsa-miR-186-5p, hsa-miR-211-5p, hsa-mir-760, PC-3p-57664, orPC-5p-12969, (b) selecting microR-NAs to upregulate selected from the group consisting of ggo-miR-139, hsa-miR-30d-5p, hsa-miR-22-3p, hsa-miR-23a-3p, mmu-miR-5124a, mmu-mir-6240-5p, PC-3p-32463, or PC-5p-211, and combinations thereof, and (c) administering an agent that: downregulates that targets in (a), upregulates the targets in (b), or both, to the subject in an amount sufficient to reduce or inhibit ischemic stroke in the mammal. The present invention also includes the detection of the markers for use with stroke patients.

Abstract: A method of detecting sub-surface voids in a sample comprises positioning a probe adjacent to a first point on the sample, emitting an ultrasonic wave from the probe towards the sample, moving the probe towards the sample, measuring a shear force amplitude of a reflection of the ultrasonic wave at the probe as the probe moves towards the sample, creating an approach curve by plotting the measured shear force amplitude of the reflection of the ultrasonic wave as a function of a distance between the probe and the sample, and determining whether a sub-surface void exists at the first point on the sample based on a slope of the approach curve.

Abstract: Provided herein are compositions comprising: a scaffold polymer having one or more acryloyl groups or one or more methacryloyl groups; optionally a porogen and a crosslinking agent, compositions that upon crosslinking form a hydrogel for use in cell encapsulation and methods for immunocytochemistry of encapsulated cells. Scaffold polymers used are selected from: Poly(ethylene glycol) diacrylate (PEGDA); Poly(ethylene glycol) dimethylacrylate (PEGDMA); Poly(ethylene glycol) methyl ether acrylate (PEGMEA); Poly(ethylene glycol) methacrylate (PEGMA); and Poly(ethylene glycol) methyl ether methacrylate (PEGMEMA), and porogens selected from: Poly(ethylene glycol) (PEG); Chitosan; Agarose; Dextran; Hyaluronic acid; Poly(methyl methacrylate) (PMMA); Cellulose and derivatives thereof; Gelatin and derivatives thereof; and Acrylamide and derivatives thereof. The invention also provides, at least in part, compositions for forming a porous hydrogel around a cell suitable for immunostaining of cells within the hydrogel.

Abstract: The present disclosure provides methods for detecting a high-risk phenotype of a mast cell tumor (MCT) in a biological sample from a mammal, preferably a dog. Kits, PCR probes and primers to detect high-risk MCT are also provided.

Abstract: An automatic nut tapping equipment is provided. The automatic nut tapping equipment includes a tap rotating mechanism, a nut clamping mechanism, an axial transmission mechanism, and a nut placing slot. The tap rotating mechanism includes a tap rotary motor and a tap, wherein the tap is driven by the tap rotary motor. The nut clamping mechanism includes a clamping assembly and a sliding rail, wherein the clamping assembly is disposed on the sliding rail and is configured for clamping a to-be-tapped nut to restrict the to-be-tapped nut from rotating. The axial transmission mechanism controls the clamping assembly to axially translate one pitch in response to the tap rotating one revolution, such that a forward nut-tapping motion and a backward nut-retracting motion are performed by the nut clamping mechanism. The nut placing slot is configured to arrange and control the dropping of another to-be-tapped nut.

Abstract: Disclosed is a method for manufacturing a functionalized separator having a zwitterionic coating thereon. The method includes preparing a porous separator; coating a linker on a surface of the porous separator; and chemically reacting zwitterions with the linker such the zwitterions are grafted to the linker on the surface of the separator. The zwitterions grafted to the linker acts as a monolayer to functionalize the surface of the separator. The functionalized separator may disallow elution of polysulfide compound in a lithium-sulfur battery. Further, the functionalized separator may increase ion conductivity of electrolyte of the lithium-sulfur battery and thus ensure high output characteristics.