Abstract: An optical encoding device includes a code disc, an optical signal generator, (K+1) optical sensors and an encoding circuit. The code disk has K gratings arranged in a row. The total width of the optical sensors is equal to the total width W of the gratings. The optical sensor receives the optical signal through the code disk. Each optical sensor converts the optical signal into a voltage signal and outputs the voltage signal. The encoding circuit receives and normalizes the voltage signals to generate (K+1) voltage values. During a period in which the code disk rotates by a distance of 2W/K, the encoding circuit compares the voltage values with a preset value to generate at least two binary codes. When K is odd, the preset value is 0.5, and when K is even, the preset value is 0.55. The present invention can increase an absolute row resolution of the code disc.
Type:
Grant
Filed:
August 13, 2019
Date of Patent:
May 18, 2021
Assignee:
National Chiao Tung University
Inventors:
Mang Ou-Yang, Yuan Ouyang, Tzu Min Chuang, Ren-Li Yang, Yung-Jhe Yan, Hou Chi Chiang
Abstract: The present invention relates to a nitrogen-doped sulfide-based solid electrolyte for all-solid batteries. The a nitrogen-doped sulfide-based solid electrolyte for all-solid batteries includes a compound with an argyrodite-type crystal structure represented by the following Formula 1: LiaPSbNcXd??[Formula 1] wherein 6?a?7, 3<b<6, 0<c?1, 0<d?2, and each X is the same or different halogen atom selected from the group consisting of chlorine (Cl), bromine (Br), and iodine (I).
Type:
Grant
Filed:
October 17, 2018
Date of Patent:
May 18, 2021
Assignees:
Hyundai Motor Company, Kia Motors Corporation, IUCF-HYU (Industry-University Cooperation Foundation Hanyang University)
Inventors:
Ju Yeong Seong, Yong Jun Jang, Hong Seok Min, Sa Heum Kim, Yong Sub Yoon, Pil Gun Oh, Dong Wook Shin, Chan Hwi Park, Jin Oh Son
Abstract: Disclosed is a CuO/Se composite film, in which Se with low melting point (221° C.) and strong photosensitivity is introduced into CuO, providing the film with fewer defects and excellent optical, electrical and photoelectric properties. In the preparation method of the invention, Se is introduced into CuO and melted by low-temperature annealing, and then the molten Se can infiltrate CuO to eliminate or reduce defects in the CuO film such as voids and dangling bonds, thereby improving optical, electrical and photoelectric properties of the film and overcoming the shortcomings that CuO has poor crystallinity, high melting point and is decomposed at a high temperature.
Type:
Grant
Filed:
December 28, 2019
Date of Patent:
May 18, 2021
Assignee:
Shaanxi Normal University
Inventors:
Fei Gao, Rongrong Gao, Hao Liu, Shengzhong Liu
Abstract: Described is a method to fabricate a gold/mesoporous silica hybrid nanoparticle. According to the process, a gold nanoparticle can be conjugated onto the surface of a mesoporous silica nanoparticle to yield a photothermal stable theranostic platform, gold/mesoporous silica hybrid nanoparticle. The nanoparticles can be useful for disease detection, treatment, and monitoring.
Abstract: Disclosed herein are amide 7-carboxybenzo[1,2,3]thiadiazoles and derivatives thereof having a general Formula I, as described herein. Combinations and compositions of these compounds are also disclosed. The compounds and compositions can be used as a plant stimulant. For example, the compounds compositions can be used to regulate the plant's growth, regulate the plant's metabolic processes, regulate the plant's physiological processes, prevent against effects of biotic stress in the plant, or prevent against effects of abiotic stress in the plant. In some embodiments, the composition can provide multiple disease resistance to plants infected with a fungus, virus, or bacteria.
Type:
Grant
Filed:
July 27, 2016
Date of Patent:
May 18, 2021
Assignee:
Adam Mickiewicz University Foundation
Inventors:
Marcin Śmiglak, Henryk Pospieszny, Rafal Kukawka, Piotr Lewandowski, Olga Stolarska, Hieronim Maciejewski
Abstract: The present invention is a Distally Assembled Steerable Cannula (DASC), a robotically-manipulated device that can be deployed and extended within a patient's body by growing from its distal end, or can be used in non-medical applications. In some embodiments, growth occurs by sequentially assembling segments that interlock to form a rigid tube with a complex 3-D shape. The segments are individually transported through the growing cannula, and then assembled at the distal end. A segment can be wedge-shaped in profile, allowing adjustment of the local radius and plane of curvature of the cannula to be controlled by relative segment orientation.
Abstract: An imaging system comprises a light source generating a pump beam, and an optical coupling system for receiving an input beam of infrared light from a scene and combining the input beam with the pump beam, wherein an intensity of the pump beam is higher than an intensity of the input beam. The imaging system further comprises a crystal configured for adiabatically mixing the beams and providing an output beam having a frequency which is a sum of frequencies of the input and pump beams, and a visible, near-infrared or ultraviolet light imager configured for collecting and to spectrally resolving the output beam.
Type:
Grant
Filed:
April 24, 2018
Date of Patent:
May 18, 2021
Assignee:
Ramot at Tel-Aviv University Ltd.
Inventors:
Haim Suchowski, Michael Mrejen, Assaf Levanon
Abstract: Various systems and methods are implemented for controlling stimulus of a cell. One such method is implemented for optical stimulation of a cell expressing an NpHR ion pump. The method includes the step of providing a sequence of stimuli to the cell. Each stimulus increases the probability of depolarization events occurring in the cell. Light is provided to the cell to activate the expressed NpHR ion pump, thereby decreasing the probability of depolarization events occurring in the cell.
Type:
Grant
Filed:
June 21, 2019
Date of Patent:
May 18, 2021
Assignee:
The Board of Trustees of the Leland Stanford Junior University
Inventors:
Karl Deisseroth, Feng Zhang, Edward Boyden
Abstract: In one aspect, the disclosure relates to methods for preparation of intermediates useful for the preparation of terpenoid cores. In a further aspect, the disclosed methods pertain to the preparation of compounds comprising a terpenoid core or scaffold, such as 6/7/5 tricycloalkanes. The disclosed methods utilize abundant starting materials and simple reaction sequences that can be used to tunably and scalably assemble common terpenoid cores. In various aspects, the present disclosure pertains to compounds prepared using the disclosed methods. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
Type:
Grant
Filed:
September 8, 2020
Date of Patent:
May 18, 2021
Assignee:
University of Florida Research Foundation, Inc.
Abstract: A multi-level cell thin-film transistor memory and a method of fabricating the same, a structure of which memory comprises sequentially from down to top: a gate electrode, a charge blocking layer, a charge trapping layer, a charge tunneling layer, an active region, and source and drain electrodes; wherein the charge tunneling layer fully encloses the charge trapping layer so as to completely isolate the charge trapping layer from the ambience, which prevents change of physical properties and chemical compositions of the charge trapping layer during the annealing treatment, reduces loss of charges stored in the charge trapping layer, and enhances data retention property and device performance stability; a metal oxide semiconductor thin film is utilized as the charge trapping layer of the memory, which implements multi-level cell storage and improves storage density.
Abstract: A trifunctional molecule comprising a target-specific ligand, a ligand that binds a protein associated with the TCR complex and a T cell receptor signaling domain polypeptide is provided. Engineering T cells with this novel receptor engenders antigen specific activation of numerous T cell functions, including cytokine production, degranulation and cytolysis.
Type:
Grant
Filed:
May 6, 2020
Date of Patent:
May 18, 2021
Assignee:
McMaster University
Inventors:
Jonathan Bramson, Christopher W. Helsen, Galina Denisova, Rajanish Giri, Kenneth Anthony Mwawasi
Abstract: Embodiments of the present disclosure provide for electroactive supramolecular polymeric assemblies, methods of making electroactive supramolecular polymeric assemblies, methods of using electroactive supramolecular polymeric assemblies, and the like.
Type:
Grant
Filed:
April 9, 2020
Date of Patent:
May 18, 2021
Assignee:
University of Florida Research Foundation, Inc.
Abstract: Disclosed herein are pyrido[3?,2?:4,5]thieno[2,3-d]pyridazin-8-amine and thieno[2,3-c:4,5-d?]dipyridazin-8-amine compounds, which may be useful as positive allosteric modulators of the muscarinic acetylcholine receptor M4 (mAChR M4). Also disclosed herein are methods of making the compounds, pharmaceutical compositions comprising the compounds, and methods of treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction using the compounds and compositions.
Type:
Grant
Filed:
November 7, 2017
Date of Patent:
May 18, 2021
Assignee:
Vanderbilt University
Inventors:
Craig W. Lindsley, Darren W. Engers, P. Jeffrey Conn, Sean R. Bollinger, Julie L. Engers
Abstract: A single-phase voltage source inverter including a first stage configured to be connectable to a DC source, and a second stage configured to be connectable to an AC load, the first stage including a bridge leg including first and second decoupling switches, the bridge leg connected through an inductor to a decoupling capacitor, where the decoupling capacitor is in series with the DC source when the inverter is connected to the DC source, and the second stage including a bi-directional H-bridge inverter including first, second, third and fourth switches. The decoupling capacitor can be a small film capacitor. The first and second decoupling switches are the only decoupling switches in the bridge leg. The first controller can use pulse width modulation and the second controller uses sinusoidal pulse width modulation. The first controller can use pulse width modulation and the second controller uses pulse energy modulation.
Abstract: Disclosed herein is a method of synthesizing a (1S,12bS) lactam ester compound, including: subjecting a dihydrocarboline diester compound of formula (II) to asymmetric hydrogenation and lactamization in an organic solvent in the presence of an iridium catalyst precursor, a chiral diphosphine ligand and a halogen-containing reagent under hydrogen atmosphere to produce the (1S,12bS) lactam ester compound of formula (I), as shown in the following reaction scheme, where R1, R2 and R3 are defined in the same manner with the specification.
Abstract: The present invention pertains to a complex including nanoparticles and, carried on the surface of the nanoparticles, a lysosomal enzyme inhibitor or kinase inhibitor shown by general formula (A) and a phospholipid mimetic substance shown by general formula (B). In general formula (A), n1 is an integer of 2-30, n2 is an integer of 2-30, the -S- terminal is a nanoparticle-carrying site, and R10 is a suicide substrate site or a kinase inhibition site. In general formula (B), n3 is an integer in the range of 2-30, and the -S- terminal is a nanoparticle-carrying site. The present invention provides a versatile system capable of efficiently delivering a drug to endolysosomes and allowing the drug to function at a low concentration on lysosomal enzymes, and an anticancer agent in which this system is used.
Type:
Grant
Filed:
January 27, 2017
Date of Patent:
May 18, 2021
Assignee:
National University Corporation Hokkaido University
Abstract: A traffic regulation system and method which combines energy harvesting from the movement of a plurality of vehicles on a roadway with wireless directional power beam transmission using the harvested energy to encourage compliance with traffic regulations. Electric power is generated from the movement of the moving vehicles by using a wind turbine to harvest wind energy from the movement of vehicles or by piezoelectric plates which harvest compression energy from the weight of the vehicle tires on the road surface. The electric power is transmitted to electric or hybrid vehicles which comply with the traffic regulations. The traffic regulations are one of driving at a posted speed and driving at a safe following distance. A control system adjusts the traffic regulation based on measurements received from a plurality of detectors.
Abstract: This invention is directed to compositions, methods and kits that can be used for the treatment or amelioration of pain and fever.
Type:
Grant
Filed:
January 9, 2020
Date of Patent:
May 18, 2021
Assignees:
The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College, University of Alcala De Hernares, South Rampart Pharma, LLC
Inventors:
Nicolas Bazan, Hernan Bazan, Julio Alvarez-Builla Gomez, Dennis Paul, Carolina Burgos Garcia