Abstract: Contemplated subject matter disclosed herein relates generally to organometallic olefin metathesis catalysts, and more particularly to longer-lived olefin metathesis catalysts supported by hemi-labile carbene ligands that bear an arm with one or more donor ligands, as well as the use of such catalysts in metathesis reactions of olefins and olefin compounds. The contemplated subject matter has utility in the fields of catalysis, organic synthesis, polymer chemistry, and industrial and fine chemicals chemistry. This contemplated subject matter serves to reduce the cost of olefin metathesis (OM) processes including in olefin metathesis polymerizations, conversion of vegetable oils into chemicals, and processes in the petrochemical industry. This contemplated subject matter reduces the cost of OM processes by providing OM catalysts that are longer-lived and lead to higher turnover numbers, hence requiring less catalyst to convert a given amount of substrate(s).

Abstract: Antenna devices are provided, including tightly coupled arrays, transmitarrays, and reflectarrays. An antenna device can include a plurality of substrates each having an antenna element. The substrates can be provided in connected series or in an array. The substrates can be part of an origami array such that the entire array is foldable. The substrates can optionally be attached to a framework that can actuate the substrates to different configurations. By bending, folding, or otherwise repositioning the substrates/array, the electromagnetic characteristics of the antenna device can be easily reconfigured for the desired task.

Abstract: A heat exchanging liquid container system comprising a main body; a phase change material (PCM) module disposable within the main body; a PCM disposed within the PCM module; a liquid reservoir defined by the main body and/or the PCM module configured to have liquid disposed therein having a first temperature; and a temperature conditioning channel formed along a wall of the PCM module and/or through the PCM module such that the temperature conditioning channel is in thermal contact with the PCM. The temperature conditioning channel configured to provide a flow path through which the liquid can flow to dispense the liquid from the liquid reservoir such that the liquid will be in thermal contact with the PCM while being dispensed. The PCM configured to exchange thermal energy with the liquid and thereby condition the liquid to be dispensed at a second temperature that is within a desired temperature range.

Abstract: A calibration platform may obtain measurements for aligning a real-world coordinate system and a display coordinate system. For example, the calibration platform may display, via an optical see-through head-mounted display (OST-HMD), a three-dimensional virtual object and receive, from a positional tracking device, information that relates to a current pose of a three-dimensional real-world object to be aligned with the three-dimensional virtual object. The calibration platform may record a three-dimensional position of a plurality of points on the three-dimensional real-world object based on the current pose of the three-dimensional real-world object, based on an indication that the plurality of points on the three-dimensional real-world object respectively corresponds with a plurality of points on the three-dimensional virtual object.

Abstract: Systems and methods for cell electroporation and molecular delivery using an intelligent, feedback controlled, microscale electroporation system for transfecting single cells.

Abstract: Disclosed herein are embodiments of a composition comprising at least three layers. Layers one and two each either comprises a sensitizer or an emitter, typically a metal ion or a dye, and the third layer may or may not comprise a sensitizer or emitter. Upon exposure to light, such as infrared light, the composition produces visible and/or UV light. The composition may further comprise a capping moiety, a therapeutic agent, an uptake enhancer, a detection moiety that binds to a desired target, a quenching moiety, or a combination thereof. The composition may be a particle, such as a nanoparticle, or it may be a planar composition. Also disclosed are embodiments of a method for using the composition, including, but not limited to, a method for delivering a therapeutic agent, or a method for detecting a target, such as a biological target.

Abstract: The present invention provides a composition that can preserve cells. The composition of the present invention includes a microbubble.

Abstract: An embodiment of a blockchain-based cryptographic key generation method and system that leverages existing values locally available within a distributed ledger to generate cryptographic keys independent of a third-party server is disclosed herein.

Abstract: Cytotoxic compounds containing a phenyl core, amide link(s), an imidazolinone or a propenamide moiety. Also described are pharmaceutical compositions incorporating the cytotoxic compounds and methods for treating cancer. These compounds are cytotoxic against breast, prostate, and leukemia cancer cell lines via dual inhibition of Src kinases and tubulin.

Abstract: A data creation method includes: an autofluorescence data generation step of placing a focus of light having a predetermined wavelength at one set of coordinates on a predetermined focal plane, irradiating a sample positioned at the set of coordinates with excitation light containing the light to obtain autofluorescence emitted from the sample, and generating autofluorescence data including intensity data and/or spectrum data of the autofluorescence; a reflected light data generation step of irradiating the set of coordinates on the predetermined focal plane with illumination light to obtain reflected light scattered by the sample, and generating intensity data of the reflected light; and a correspondence data creation step of creating correspondence data associating the autofluorescence data and the reflected light data on the set of coordinates on the predetermined focal plane.

Abstract: A polysulfone has sulfone units that are separated by alkylene units in a polymer chain or a copolymer chain where the alkylene units have at least four carbons between sulfone units. The alkylene units can include an ethenylene unit separated from the sulfone units by at least one methylene units. The polysulfones can be crosslinked for enhanced thermal stability. Membranes can be formed from the polysulfones.

Abstract: An XYZ flexural mechanism comprising an X-axis flexural mechanism comprising a first voice coil actuator, a motion stage platform, a plurality of flexural bearings, and a plurality of guide rods, a Y-axis flexural mechanism comprising a second voice coil actuator, a plurality of flexural bearings, a plurality of guide rods, and a frame, and a Z-axis flexural mechanism comprising a third voice coil actuator, a plurality of flexural bearings, a plurality of guide rods, and a frame, the frame supporting the XYZ flexural mechanism.

Abstract: A metallic quantum well may be formed by interposing a layer of metallic well material two layers of barrier material. Two or more metallic quantum wells may be combined to form a coupled metallic quantum well. The absorption spectrum and the emission spectrum of the coupled metallic quantum well may be tuned by at least adjusting the dimensions of the individual metallic quantum wells and/or the materials forming the metallic quantum wells. The metallic quantum well and/or the coupled metallic quantum well may exhibit sufficient nonlinearity even at a miniaturized scale. As such, the metallic quantum well and/or coupled metallic quantum well may be used for a variety of on-chip applications including, for example, as part of an on-chip pulse limiter, an on-chip super-continuum generator, and/or the like.

Abstract: A base element for switching a magnetization state of a nanomagnet includes a heavy-metal nanostrip having a surface. A ferromagnetic nanomagnet is disposed adjacent to the surface. The ferromagnetic nanomagnet includes a shape having a long axis and a short axis. The ferromagnetic nanomagnet has both a perpendicular-to-the-plane anisotropy Hkz and an in-plane anisotropy Hkx and the ferromagnetic nanomagnet has a first magnetization equilibrium state and a second magnetization equilibrium state. The first magnetization equilibrium state or the second magnetization equilibrium state is settable by a flow of electrical charge through the heavy-metal nanostrip. A direction of flow of the electrical charge through the heavy-metal nanostrip includes an angle ? with respect to the short axis of the nanomagnet.

Abstract: The present invention relates to systems, devices and methods for diagnosing cancer. In various embodiments, the present invention provides a method for quantifying a 5?-htRNA; a method for quantifying a 3?-htRNA; a method for obtaining a DNA library of 5?-htRNAs and a DNA library of 5?-htRNAs obtained therefrom; and a method for obtaining a DNA library of 3?-htRNAs and a DNA library of 3?-htRNAs obtained therefrom. The invention also teaches a method for determining the presence or absence of a cancer cell in a biological sample; a method of diagnosing cancer in a subject; and a method of prognosing cancer in a subject.

Abstract: Linear actuators are disclosed. The linear actuator comprises a thruster and a stator. The thruster includes a thruster winding, and the stator includes a stator winding. The stator is disposed about the thruster. The linear actuator also includes a sheath disposed about the stator and the thruster. The thruster is configured to translate within the sheath relative to the stator upon application of an electrical current to the stator winding, the thruster winding, or a combination thereof. The stator winding and the thruster winding each comprise a nonpermanent magnet.

Abstract: The methods and configurations herein provide for analysis of microplate based assays. Certain aspects include: an optical illumination panel; a plurality of sample wells configured to receive light from the optical illumination panel, and wherein the plurality of sample wells is configured with a first field of view; at least one aperture array configured to isolate directed light therethrough the plurality of sample wells; at least one optical array configured to receive optical information from the plurality of sample platforms, wherein the at least optical array comprises an array of individual microprisms configured with equal apex angles at distal equidistances along a row, wherein the individual microprism apex angles decrease toward the center of the row culminating in at least one flat surface along a center portion of the row; and a detector configured to capture the optical information with a second field of view as provided by the at least one optical array.

Abstract: The present disclosure provides advantageous composite films/coatings, and improved methods for fabricating such composite films/coatings. More particularly, the present disclosure provides improved methods for fabricating composite films by trapping at least a portion of a layered material (e.g., hexagonal boron nitride sheets/layers) at an interface of a phase separated system and then introducing the layered material to a polymer film. The present disclosure provides for the use of boron nitride layers to increase the properties (e.g., dielectric constant and breakdown voltage) of polymer films. The exemplary films can be produced by an advantageous climbing technique. Exemplary boron nitride films are composed of overlapping boron nitride sheets with a total thickness of about one nanometer, with the film then transferred onto a polymer film, thereby resulting in significant increases in both dielectric and breakdown properties of the polymer film.

Abstract: The present disclosure provides micro-array devices for capturing cells in blood and methods of their use. In some aspects, a method for counting cells in a blood sample is provided, the method comprising applying a blood sample onto a CNT device; allowing cells in the blood sample to differentially settle on the CNT device, and identifying and counting cells of preselected type in the blood sample.

Abstract: Mapping and localization using image processing of wireless signals is provided. Embodiments of the present disclosure provide a novel approach for high accuracy mapping of an environment around an antenna (or antenna array) coupled to a radio frequency (RF) transceiver through image processing of RF signals. The image processing includes constructing a map of line-of-sight (LOS) and non-line-of-sight (NLOS) objects in the environment by distinguishing NLOS objects and correctly projecting their positions relative to the LOS objects. In some examples, a three-dimensional (3D) image of the environment around the antenna (or antenna array) is produced. Aspects disclosed herein can further provide simultaneous localization and mapping (SLAM) for a wireless device.