Abstract: The wide application of power electronic components in power systems with renewable energy sources has changed the fault characteristics of conventional power systems, resulting in the performance degradation of conventional protections. To solve these problems, a novel principle of pilot protection based on structural similarity and square error criteria is provided. The structural similarity criterion utilizes the difference of fault characteristics between renewable sources and synchronous generators to identify internal faults, and the square error criterion is used to solve abnormal calculation of the conventional similarity based protection. Compared with conventional differential protections, the disclosed protection shows excellent performance in speed and reliability during various faults.
Abstract: The present invention features anti-HERV-K monoclonal antibodies or antigen-binding portions thereof. The present invention also features uses of the antibodies for treating HIV infection or HIV-associated conditions or diseases.
Type:
Grant
Filed:
August 30, 2017
Date of Patent:
April 20, 2021
Assignees:
University of Rochester, Oregon Health & Science University, George Washington University
Inventors:
James J. Kobie, Jonah B. Sacha, Douglas F. Nixon
Abstract: A coupling system can include an energy transfer device and a load mitigation system. The energy transfer device can include a shaft, gear, chain or piston-cylinder arrangement to transfer the energy from a power supply to an object to be moved. The load mitigation system can be used to limit or prevent the transfer of forces from the object to the drive unit as a result of external loads being applied to the object. The load mitigation system can be pre-loaded such that external loads on the object having an excessive impulsive or resonant cyclic force greater than the pre-load force on the load mitigation system are reduced and only partially transferred to the energy transfer device and power supply. The load mitigation system can dampen both resonant loads and impulsive impact loads occurring at the object thereby preventing damage and extending life.
Type:
Grant
Filed:
April 13, 2018
Date of Patent:
April 20, 2021
Assignee:
Board of Trustees of the University of Alabama, for and on behalf of the University of Alabama in Huntsville
Abstract: Methods for identification and quantification of bile acids are disclosed. Bile acids in plasma, serum and/or blood such as a dried blood spot are used to identify subjects with a Niemann-Pick disease. The methods include measuring levels of a bile acid, such as 3?,5?,6?-trihydroxycholanic acid, N-(3?,5?,6?-trihydroxy-cholan-24-oyl)glycine, N-(3?,5?,6?-trihydroxy-cholan-24-oyl)taurine, or a combination thereof. Detection of bile acids involve mass spectroscopy and/or a combination of mass spectroscopy and liquid chromatography such as a LC-MS/MS assay. The methods can be used with sphingomyelinase assays to detect, diagnose and differentiate between Niemann-Pick A/B and Niemann-Pick C (NPC) disease.
Abstract: The present invention concerns methods and compositions for evoking protective immune responses against pathogen infection or cancer. In certain embodiments, the methods and compositions comprise a lymphangiogenesis inducer and an antigen.
Type:
Grant
Filed:
April 28, 2017
Date of Patent:
April 20, 2021
Assignee:
The University of Chicago
Inventors:
Melody A. Swartz, Jeffrey A. Hubbell, Shann Yu, Efthymia Vokali, Manuel Fankhauser, Sachiko Hirosue, Priscilla S. Briquez, Maria Broggi, Lambert Potin, Maria Stella Sasso
Abstract: Disclosed are a method of preparing a zeolite nanosheet and a zeolite nanosheet particle prepared thereby, and more particularly a method of preparing a zeolite nanosheet capable of preparing a monolayer zeolite nanosheet through a simple process of mixing a multilayer zeolite precursor with a swelling agent to swell the multilayer zeolite precursor and drying and calcining the multilayer zeolite precursor, wherein the monolayer zeolite nanosheet is useful to separate a catalyst or gas, and a zeolite nanosheet particle prepared thereby.
Type:
Grant
Filed:
August 14, 2020
Date of Patent:
April 20, 2021
Assignee:
Korea University Research and Business Foundation
Inventors:
Jungkyu Choi, Kwan Young Lee, Eun-Hee Jang
Abstract: A rotatory resectoscope is disclosed with a novel mechanism for endoscopic resection. Resection is performed by a rotary motion instead of the conventional linear motion. A novel resection loop and working element for controlling the movement of the resection loop allow the resection loop to move in clockwise and counterclockwise rotation. Embodiments include both monopolar and bipolar diathermy resectoscopes.
Type:
Grant
Filed:
August 19, 2020
Date of Patent:
April 20, 2021
Assignee:
King Abdulaziz University
Inventors:
Omar A. Fahmy, Nabil A. Alhakamy, Osama A. Ahmed, Usama A. Fahmy, Shadab Md
Abstract: A method of generating a cell that enhances functional myelin production is provided, the method including genetically modifying the cell such that: (i) an endogenous PLP1 gene is modified to decrease its ability to inhibit myelin production; (ii) an endogenous PLP1 genetic regulatory element is modified to decrease its ability to promote PLP1 expression; (iii) an endogenous PLP1 genetic regulatory element is modified to increase its ability to inhibit PLP1 expression; or (iv) an endogenous PLP1 gene product or a PLP1 regulatory element gene product that promotes PLP1 expression is modified to decrease the PLP1 expression level, wherein the cell produces functional myelin.
Abstract: Computationally efficient, highly accurate, and cost-effective approach for detection of damage in a structure is described. Methods include a combined analysis in both global and local regions of a structure to predict the received wave signals at a location due to scattering of Lamb waves at a damage site. Through comparison of an actual received wave signal with the predicted signals, identification of damage location and/or type can be provided. Methods can be particularly beneficial when considering damage assessment in a complex structure that includes plate-like structures that include an extension off of a base plate, e.g., a stiffened structure.
Type:
Grant
Filed:
April 29, 2019
Date of Patent:
April 20, 2021
Assignees:
University of South Carolina, Intelligent Automation, Inc.
Inventors:
Victor Giurgiutiu, Mohammad Faisal Haider, Banibrata Poddar
Abstract: The present invention relates to a system, device, and method for the high throughput multiplexed detection of a wide number of compounds. The invention comprises of a microwell array coupled to a capture agent array to form a plurality of interfaces between a microwell and a set of immobilized capture agents. The set of capture agents comprises a plurality of distinguishable features, with each feature corresponding to the detection of a particular compound of interest. In certain embodiments, each microwell is configured to contain a single cell. The invention is therefore capable of performing a high throughput analysis of single cell profiles, including profiles of secreted compounds.
Abstract: The present disclosure discloses a fluorescent dispersed particle gel, a fluorescent gel, a fluorescent modified polyacrylamide composite, and a preparation method and use thereof.
Type:
Grant
Filed:
June 12, 2020
Date of Patent:
April 20, 2021
Assignees:
China University of Petroleum (East China), The Research Institute of Petroleum Exploration and Development (RIPED) of the Petro China Company Limited (Petro China), China University of Geosciences (Beijing)
Abstract: It is disclosed herein that microperoxidases are capable of binding carbon monoxide (CO) with high affinity and displacing CO from hemoglobin, thereby acting as CO scavengers. The present disclosure provides methods of treating carboxyhemoglobinemia (or CO poisoning) in a subject by administering a therapeutically amount of an isolated or recombinant microperoxidase. Methods of removing CO from hemoglobin in blood or tissue by administering a therapeutically amount of an isolated or recombinant microperoxidase are also described. Methods of determining the effectiveness of a microperoxidase for removing CO from hemoglobin are further described.
Type:
Grant
Filed:
May 19, 2015
Date of Patent:
April 20, 2021
Assignee:
University of Pittsburgh—Of the Commonwealth System of Higher Education
Inventors:
Mark Thomas Gladwin, Jesus Tejero Bravo
Abstract: An inter-prediction method according to the present invention comprises the steps of: deriving motion information of a current block; and generating a prediction block for the current block on the basis of the derived motion information. According to the present invention, computational complexity can be reduced and encoding efficiency can be improved.
Type:
Grant
Filed:
November 26, 2019
Date of Patent:
April 20, 2021
Assignees:
Electronics and Telecommunications Research Institute, University-Industry Cooperation Group of Kyung Hee University
Inventors:
Hui Yong Kim, Gwang Hoon Park, Kyung Yong Kim, Sung Chang Lim, Jin Ho Lee, Jin Soo Choi, Jin Woong Kim
Abstract: A blood flow measurement apparatus of an embodiment includes an image acquisition unit, an image region specification unit, a measurement location setting unit, a scanner, and a blood flow information generation unit. The image acquisition unit acquires an image of a living body. The image region specification unit analyzes the image to specify a plurality of blood vessel regions. The measurement location setting unit sets a plurality of measurement locations that intersects with the plurality of blood vessel regions. The scanner scans a plurality of cross sections of the living body corresponding to the plurality of measurement locations using optical coherence tomography. The blood flow information generation unit generates blood flow information on the living body based on data acquired through the scan.
Type:
Grant
Filed:
November 2, 2015
Date of Patent:
April 20, 2021
Assignees:
National University Corporation ASAHIKAWA MEDICAL UNIVERSITY, KABUSHIKI KAISHA TOPCON
Abstract: The present invention provides an analysis method for determining halogens in geological samples by ICP-MS. The method includes following steps: weighing a geological sample and ammonium bifluoride in a sample dissolving tank, tightening the sample dissolving tank, and shaking; then heating the sample dissolving tank in a drying oven, and setting a temperature of the drying oven as 200-220° C. and heating time as 1-2 hours; cooling the sample dissolving tank to room temperature so as to obtain a solid mixture after heating is ended, adding ammonium hydroxide into the solid mixture, centrifuging, removing a precipitate, and collecting the supernatant; adding an internal standard solution into the supernatant, and uniformly mixing; and optimizing the ICP-MS to an optimal state, testing content of chlorine in the supernatant under a condition of medium resolution m/?m=4000, and testing content of bromine and iodine in the supernatant under a condition of low resolution m/?m=300.
Type:
Grant
Filed:
March 26, 2020
Date of Patent:
April 20, 2021
Assignee:
China University of Geosciences, Wuhan
Inventors:
Zhaochu Hu, Tao He, Wen Zhang, Haihong Chen, Ming Li, Yongsheng Liu
Abstract: Described are glutathione adducts of fatty aldehydes (FALD-GSH) and methods useful in the detection of FALD-GSH in the identification of pathologies associated with leukocyte-mediated disease conditions, including eosinophil and neutrophil activation. Thus, the present disclosure provides methods of diagnosing a subject as having or being at risk of developing a leukocyte-mediated disease (LMD) comprising (a) detecting the level of glutathione adducts of 2-halofatty aldehydes (FALD-GSH) in a sample; (b) comparing the amount of FALD-GSH with a control or standard reflective of diseased and/or healthy levels of FALD-GSH; and (c) diagnosing the subject as having or being at risk of developing LMD if the level of FALD-GSH in the sample is higher than the control or standard.
Abstract: Provided herein are green alga Cia8 polypeptides and the polynucleotides that encode them. Also provided herein are transformed cells and transgenic plants that include one or more of the polynucleotides and/or polypeptides provided herein.
Type:
Grant
Filed:
June 20, 2017
Date of Patent:
April 20, 2021
Assignee:
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
Inventors:
James V. Moroney, Marylou C. Machingura, Joanna N. Bajsa-Hirschel
Abstract: The present invention provides benzothiadiazine and chroman derivatives and particularly diazoxide and cromakalim derivatives for use in treating glaucoma, retinopathy, treating age related macular degeneration, treating, stabilizing and/or inhibiting blood and lymph vascularization, and reducing intraocular pressure by administering a pharmaceutically effective amount of a prodrug disposed in an ophthalmically acceptable carrier to the eye, wherein the prodrug specifically modulates a KATP channel to reduce an intraocular pressure.
Type:
Grant
Filed:
January 30, 2015
Date of Patent:
April 20, 2021
Assignees:
Mayo Foundation for Medical Education and Research, Regents of the University of Minnesota
Inventors:
Michael P. Fautsch, Peter Dosa, Michael A. Walters, Gunda I. Georg
Abstract: The present invention relates to the field of analog integrated circuits, and provides a multiply-accumulate calculation method and circuit suitable for a neural network, which realizes large-scale multiply-accumulate calculation of the neural network with low power consumption and high speed. The multiply-accumulate calculation circuit comprises a multiplication calculation circuit array and an accumulation calculation circuit. The multiplication calculation circuit array is composed of M groups of multiplication calculation circuits. Each group of multiplication calculation circuits is composed of one multiplication array unit and eight selection-shift units. The order of the multiplication array unit is quantized in real time by using on-chip training to provide a shared input for the selection-shift units, achieving increased operating rate and reduced power consumption.
Type:
Grant
Filed:
January 24, 2019
Date of Patent:
April 20, 2021
Assignee:
Southeast University
Inventors:
Bo Liu, Yu Gong, Wei Ge, Jun Yang, Longxing Shi
Abstract: The present invention discloses a single-drive bidirectional-crawling pipe-cleaning robot, including a front body assembly, a transmission assembly, and a rear body assembly. The transmission assembly is driven by a single power source, and a transmission effect of a connecting rod mechanism, a gear mechanism, and an equal-dwell cam mechanism is used to implement alternate retraction and support of the front body assembly and the rear body assembly in a radial direction and a telescopic motion in an axial direction between the front body assembly and the rear body assembly and at the same time implement synchronous rotation of a dredging cutter head, so as to implement bidirectional crawling and pipe cleaning work of the robot along a pipe.
Type:
Grant
Filed:
November 13, 2017
Date of Patent:
April 20, 2021
Assignees:
China University of Mining and Technology, Xuzhou Zhirun Mining Equipment Science and Technology Co., Ltd