Abstract: A post-processing leakage correction system and method that accounts for bidirectional contrast agent transport between the intravascular and interstitial spaces that commonly occurs in angiogenic high-grade gliomas without a substantial increase in post-processing computation time.

Abstract: Embodiments concern methods and small molecule compositions for selectively inhibiting RAD51-mediated D-loop formation while preserving RAD51's ability to form nucleoprotein filaments. The selective RAD51 D-loop formation activity inhibitors DNA repair while minimizing replication-associated toxicity in normal tissue.

Abstract: A self-priming water turbine-driven reel sprinkler irrigation machine includes a framework, a plug board, a reel, a PE pipe, a water turbine driving device, a sprinkler wagon, and a self-priming device. The framework comprises an underframe, a reel support frame, a plug board support frame, and a wheel assembly. A bottom portion of the underframe is provided with an underframe rotary device, and the underframe rotary device comprises a rotary bearing and a chassis support member. An inner ring of the rotary bearing is fixedly mounted to the underframe, and an outer ring of the rotary bearing is fixedly mounted and connected to the chassis support member. A telescopic front support is disposed at a front part of the underframe. The wheel assembly comprises a wheel support beam, a wheel, and a wheel lifting hydraulic cylinder. The self-priming device comprises a water pump, a pumping hose, and a filtering mechanism.

Abstract: In vitro and in vivo methods of removing carbon monoxide from hemoglobin in blood or animal tissue are described. Methods of treating carboxyhemoglobinemia (carbon monoxide poisoning) in a subject are also described. The methods include administering natural or artificial oxygen carriers that are in their reduced form. Methods of producing a reduced oxygen carrier are further described. Methods of treating cyanide poisoning or hydrogen sulfide poisoning with oxygen carriers are also described.

Abstract: This invention relates to peer-to-peer transparent clocks and methods of estimating skew in peer-to-peer transparent clocks. Embodiments of the invention relate to techniques for estimating clock skew between a free-running clock in a transparent clock and a master clock, in particular by using the timing information embedded in timing messages passing through the transparent clock. Further embodiments of the invention set out uses of these estimates to modify the residence times computed by the transparent clock and a synchronization network including such transparent clocks.

Abstract: The present invention is intended to provide a highly versatile and simple technique which can increase the expression level of a protein in an E. coli expression system or a yeast expression system. Using an E. coli expression system or a yeast expression system, a target protein is expressed as a tag-added protein to which a peptide tag composed of an amino acid sequence SK, SKX, SKXX (SEQ ID NO. 1), AKXX (SEQ ID NO. 29), or KKXX (SEQ ID NO. 30) (wherein X represents any amino acid residue) is linked at the N-terminal.

Abstract: A method of regulating plant stomata conductance is provided. The method comprises modulating in the plant the level and/or activity of a type B hexokinase in a guard cell specific manner, thereby regulating plant conductance.

Abstract: Systems and methods for generating and tracking molecular digital signatures to ensure authenticity and integrity of NA molecules are disclosed. In some embodiments, a NA authentication system includes a NA authentication device coupled to one or more user devices. Methods for generating a signed NA sequence, validating a signed NA sequence, and detecting/correcting potential errors within a user allowable limit using a NA authentication system are disclosed.

Abstract: This system and method provide for manufacturing a multi-material hybrid structure comprising a single- or multi-layer sheet or tube, which are made of metals, fabrics, polymer and their combinations, and at least one layer or body made of formed resin. The methods include a simultaneous forming-injection process that followed with an additional sequence to initiate the forming process along with curing and/or solidification and/or bonding processes. The additional sequence provides a pressure drop inside the cavity using tool movement and or additional deformation of one/or several layers of the sheet using any fluid pressure, suction and/or electromagnetic force. The injection process can be used for any kind of synthetic or bio-based resin with or without fiber reinforcement. It is also integrated with supercritical assisted technology.

Abstract: A hybrid propulsion system includes a housing, at least two electrodes, a solid-grain fuel material, a combustion chamber, an oxidizer port, and a nozzle. The housing has a first end and a second end and defines a cavity. The electrodes extend into the cavity. The fuel material is free of an oxidizer and is positioned in the cavity. The fuel material has a combustion surface and is exposed to the electrodes. The combustion chamber is defined between the combustion surface and the second end. The oxidizer port provides a flow of oxidizer to the combustion chamber. The nozzle is positioned at the second end. Combustion of the fuel material in the combustion chamber may be dominated by radiative heat transfer. Combustion of the fuel material in the combustion chamber may generate thrust of no more than 5 N at an oxidizer flow rate of no more than 5 g/s.

Abstract: Quantum network devices, systems, and methods are provided to enable long-distance transmission of quantum bits (qubits) for applications such as Quantum Key Distribution (QKD), entanglement distribution, and other quantum communication applications. Such systems and methods provide for separately storing first, second, third, and fourth photons, wherein the first and second photons and the third and fourth photons are respective first and second entangled photon pairs, triggering a synchronized retrieval of the stored first, second, third, and fourth photons such that the first photon is propagated to a first node, the second and third photons are propagated to a second node, and the fourth photon is propagated to a third node, and creating a new entangled pair comprising the first and fourth photons at the first and third nodes to transmit quantum information.

Abstract: Provided are isolated TCRs, TCR-like molecules, and portions thereof that bind to phosphopeptide-HLA-A2 complexes. The isolated TCRs, TCR-like molecules, or portions are optionally soluble TCRs, TCR-like molecules, or portions. Also provided are isolated nucleic acids encoding the disclosed TCRs, TCR-like molecules, or portions; host cells that contain the disclosed TCRs, TCR-like molecules, or portions; pharmaceutical compositions that include the disclosed TCRs, TCR-like molecules, portions, nucleic acids, and/or T cells; kits; and methods of using the same.

Abstract: A composite is formed from a combination of a polymer and pulverized coal and optionally a compatibilizing agent. The coal forms from about 10 to about 80% of the composite. The composite is form by blending the pulverized coal with the polymer to form the composite.

Abstract: A method is disclosed for making palatable methionine-restricted foods, to deliver a methionine-restricted diet to human or veterinary patients. A protein or a food product containing protein is partially oxidized, preferably with ozone, to oxidize nearly all of the methionine and cysteine. After oxidation, tryptophan and lysine are optionally added back since they tend to be oxidized also. Optionally, a small amount of methionine is also added back so that the final methionine is within a preferred range of about 0.85 to about 1.8 gram methionine per 100 gram total protein, preferably about 1.2 gram per 100 gram total protein.

Abstract: A method of removing an organic pollutant from water by contacting the water with a ball milled and sonicated oil fly ash powder to adsorb the organic pollutant onto the ball milled and sonicated oil fly ash powder. A method of producing a ball milled and sonicated oil fly ash powder involving ball milling oil fly ash to provide ball milled oil fly ash particles with an average particle size of less than 1 ?m and sonicating the ball milled oil fly ash particles in an aqueous medium to form the ball milled and sonicated oil fly ash powder. A method of improving recovery of valuable metals/elements from oil fly ash.

Abstract: An autonomous mobile robot includes a first arithmetic unit configured to calculate a course direction based on an own position, a moving-object position, and a moving-object velocity vector, the course direction being a direction in which the autonomous mobile robot should travel, a second arithmetic unit configured to input the own position, the moving-object position, the moving-object velocity vector, and the course direction into a trained model and thereby calculate an estimated position, the trained model being a model that has been trained, the estimated position being a position at which the autonomous mobile robot is estimated to arrive a predetermined time later without colliding with the moving object, a generating unit configured to generate a remaining route from the estimated position to a destination, and a movement control unit configured to control a movement to the destination based on the course direction and the remaining route.

Abstract: The present invention provides a skull implant-type automatic fluid drain device comprising: a body having a first port to be connected to a catheter, a second port provided opposite the first port, and a flow passage connecting the first port and the second port; a separation member for separating the flow passage into first and second sub-channels; a first valve fixed to the separation member and provided to allow the movement of a fluid that moves from the first port to the second port in the first sub-channel; and a second valve fixed to the separation member and provided to allow the movement of a fluid that moves from the second port to the first port in the second sub-channel, wherein each of the first valve and the second valve has an inflow end portion that is open and a discharge end portion provided in a closed state such that the same is selectively opened at an allowed opening pressure or higher; each of the first valve and the second valve is configured such that the inner flow sectional area de

Abstract: A combination of three well-known and FDA approved compounds has been discovered to significantly suppress the proliferation of pancreatic cancer cells in clinically relevant models of pancreatic cancer. Embodiments of the invention include compositions of matter comprising a combination of agents such as metformin, simvastatin, and digoxin as well as methods of treating cancers using such agents. Illustrative methods include combining a population of pancreatic cancer cells with amounts of metformin, simvastatin, and digoxin sufficient to inhibit expression of BIRC5 protein in the population of pancreatic cancer cells, thereby inhibiting the growth of the population of pancreatic cancer cells.

Abstract: Provided is a method for preventing, ameliorating, suppressing the progression of, and/or treating a tumor caused by a tumor virus, the method including the step of administering, to a subject, an effective amount of a component that targets a gene product of the tumor virus.

Abstract: The invention provides a process for depositing a coating onto particles being pneumatically transported in a tube. The process comprising the steps of providing a tube having an inlet opening and an outlet opening; feeding a carrier gas entraining particles into the tube at or near the inlet opening of the tube to create a particle flow through the tube; and injecting a first self-terminating reactant into the tube via at least one injection point downstream from the inlet opening of the tube for reaction with the particles in the particle flow. The process is suitable for atomic layer deposition and molecular layer deposition. An apparatus for carrying out the process is also disclosed.