Abstract: Accurate and effective methods for measuring cardiovascular and respiratory parameters are provided. The method for deriving a depth-specific photoplethysmography (PPG) signal from multi-wavelength PPG signals includes choosing light wavelength combinations, calibrating a multi-layer light-tissue interaction model referring to a physiological signal, and generating the depth-specific PPG signal from the multi-wavelength PPG signals based on the calibrated light-tissue interaction model. The disclosed method for cuff-less blood pressure measurement includes recording a physiological signal and multi-wavelength PPG signals of a predetermined body part, deriving the depth-specific PPG signal reflecting the arterial blood volume with the physiological signal as a reference, calculating the pulse transit time (PTT) from the physiological signal and the derived arterial blood PPG signal, and calculating the blood pressure from the calibrated PTT and blood pressure relationship.

Abstract: Provided herein are methods for preparing a functionalized polyolefin from an unsaturated polyolefin containing one or more non-aromatic main-chain double bonds and for reducing the size and/or polydispersity index (i.e., increasing the homogeneity) of the unsaturated polyolefin.

Abstract: Wireless power transfer systems in accordance with embodiments of the invention are disclosed. In one embodiment, a wireless power transfer system includes a power transmitter driven by an oscillator, a power receiver including a resistive load, and a coupled resonator link configured to deliver power from a transmitter tank circuit to a receiver tank circuit, wherein the free-running oscillator automatically tunes to oscillate at a frequency that does not experience a phase shift due to the impedance of the transmit side of the coupled resonator link, wherein the power transmitter provides regulated voltage across a range of distances between the transmitter tank circuit and the receiver tank circuit, and wherein the power transmitter regulates voltage across a range of resistive loads of the power receiver.

Abstract: The present invention provides a method of inhibiting, suppressing or preventing levodopa-induced dyskinesia in a patient suffering from Parkinson's Disease, comprising the step of administering to the patient a pharmaceutical composition comprising at least one compound of the invention. The present invention further provides a method of inhibiting, suppressing or preventing Parkinson's Disease in a patient, comprising the step of administering to the patient a pharmaceutical composition comprising at least one compound of the invention.

Abstract: Rhein analogues that exhibit anti-proliferative activity, particular against cancer cells, are described herein. In some embodiments, the compounds contain a flat or planar ring system. Such rings system by facilitate non-covalent binding of the compounds to the DNA complex, such as by intercalation. In some embodiment, the compounds contain a flat or planar ring system as described above and one or more substituents which are alkylating moieties, electrophilic groups or Michael acceptors or groups which contain one or more alkylating moieties, electrophilic groups and/or Michael acceptors. The compounds described herein can also contain one more functional groups to improve the solubility of the compounds.

Abstract: Systems and methods for designing RF pulses using a technique that directly controls temperature rise via a compression model that is based on virtual observation points (“VOPs”) are provided. Thermal pre-simulations are first carried out for a given RF exposure time, coil, and subject model in order to obtain complex temperature matrices, after which the compression scheme follows. As one example, the thermal model employed can be Pennes' bio-heat equation. Focusing design constraints on the temperature rise instead of the absolute temperature allows for uncertain parameters to be dropped from the thermal model, making it more robust and less prone to errors. In some embodiments, the algorithm used for RF pulse design is the active-set (“A-S”) method.

Abstract: A device is described having a first surface having a plurality of first areas and a second surface having a plurality of second areas. The first surface and the second surface are opposed to one another and can move relative to each other from at least a first position where none of the plurality of first areas, having a first substance, are exposed to plurality of second areas, having a second substance, to a second position. When in the second position, the plurality of first and second areas, and therefore the first and second substances, are exposed to one another. The device may further include a series of ducts in communication with a plurality of first second areas to allow for a substance to be disposed in, or upon, the plurality of second areas when in the first position.

Abstract: A lithium deficient cathode active material for lithium-ion batteries is described. More particularly, the lithium deficient cathode active material can have multiphase structures, including both a layered or hexagonal structure (e.g., having an R-3m space group) and a spinel structure (e.g., having a Fd-m space group). Batteries including the cathode active material and methods of preparing the cathode active material are also described.

Abstract: System and method based upon an OFDM symbol, including a cyclic prefix (CP), that is received after being transmitted over a multiple access channel, wherein the CP is removed, and a Hann window is applied to the symbol. FFT is then applied to the Hann windowed symbol to obtain the frequency domain subcarriers. The pilot symbols are filtered accordingly to obtain Hann windowed pilots to estimate effective channel. Inter-carrier interference is calculated and removed.

Abstract: A method includes a mobile device receiving data from a first beacon in a plurality of beacons, wherein the data indicates a plurality signals strengths of signals received by the first beacon from the other beacons in the plurality of beacons. The mobile device uses multivariable regression based on the data received from the first beacon and signal strengths of signals received by the mobile device from the other beacons in the plurality of beacons to determine distances from the mobile device to the beacons. The mobile device determines a location of the mobile device based on the determined distances.

Abstract: Apparatuses, systems, ambient RF backscatter transceivers, and methods for communicating using MIMO and spread spectrum coding of backscattered ambient RF signals are described. An example system may include an ambient RF backscatter transceiver that include an antenna configured to receive a backscattered ambient radio frequency (RF) signal, and a receiver coupled to the antenna. The receiver may be configured to demodulate the backscattered ambient RF signal using one of multiple input, multiple output multiplexing demodulation or spread spectrum code demodulation to retrieve the first data. The backscattered ambient RF signal may be generated by backscattering an ambient RF signal at a first frequency. The ambient RF signal may be configured to provide other data at a second frequency.

Abstract: A laser system for modifying the index of refraction of an optical hydrogel material. The laser system comprises a computer program to determine the position and shape of refractive structures to be written into the optical hydrogel material to correct a patient's vision, and a focused laser that generates laser light having a wavelength of from 400 nm to 900 nm, and which operates with an average power of 10 mW to 1000 mW to produce a pulse energy from 0.05 nJ to 1000 nJ with a peak intensity at focus of greater than 1013 W/cm2. The refractive structures exhibit a change in the index of refraction of 0.01 to 0.06 in the optical hydrogel material.

Abstract: Non-disperse, periodic microplasmas are generated in a volume lacking interfering structures, such as electrodes, to enable photonic interaction between incident electromagnetic energy and the non-disperse, periodic microplasmas. Preferred embodiments leverage 1D, 2D, 3D and super 3D non-disperse, periodic microplasmas. In preferred embodiments, the non-disperse, periodic microplasmas are elongate columnar microplasmas. In other embodiments, the non-disperse, periodic microplasmas are discrete isolated microplasmas. The photonic properties can change by selectively activating groups of the periodic microplasmas.

Abstract: Methods and compositions are provided for generating macrocyclic peptides from genetically encoded, ribosomally produced polypeptide precursors. Also provided are nucleic acid molecules, polypeptides, and methods for generating combinatorial libraries of macrocyclic peptides. These methods can be used to produce vast libraries of conformationally constrained peptide ligands as well as facilitate the functional screening of these libraries to identify compound(s) with desired activity properties.

Abstract: A colored special effect ink includes a special effect pigment and a colored pigment. The colored pigment is more hydrophobic than the special effect pigment, and the colored pigment is miscible in a solvent chosen from the group consisting of alcohols, ethers, esters, ketones, and water. The colored pigment optionally has a surface energy of less than 35 dynes/cm. A method for preparing the colored special effect ink and treating the colored pigment to form the colored special effect ink are also described.

Abstract: The present invention relates to compounds that are useful as metal ligands and which either contain a molecular recognition moiety or can be bound to a molecular recognition moiety and methods of making these compounds. Once the compounds that contain a molecular recognition moiety are coordinated with a suitable metallic radionuclide, the coordinated compounds are useful as radiopharmaceuticals in the areas of radiotherapy and diagnostic imaging. The invention therefore also relates to methods of diagnosis and therapy utilising the radiolabelled compounds of the invention.

Abstract: In one embodiment of the present disclosure, a device is disclosed comprising a macroscopic thermal body and an extraction structure that is electromagnetically-coupled to the thermal emitting area of the thermal body. The macroscopic thermal body having a thermal emitting area, and the extraction structure configured and arranged to facilitate emission from, or receipt to the thermal emitting area that exceeds a theoretical, Stefan-Boltzmann, emission limit for a blackbody having the same thermal emitting area as the thermal body.

Abstract: An image processing apparatus includes a core configured to perform a fast Fourier transformation (FFT) operation on the image data, a memory configured to store data that is output by the core, and a controller configured to control the core to perform the FFT operation on the image data. The core is resettable based on an amount of the image data.

Abstract: The present invention relates to an arrangement for the generation of images of optical sections of a three-dimensional (3D) volume in space such as an object, scene, or target, comprising: an illumination unit, an optical arrangement for the imaging of the object onto at least one spatially resolving detector, a scanning mechanism for scanning the entire object and a signal processing unit for the implementation of a method for digital reconstruction of a three-dimensional representation of the object from images of said object as obtained by said detector (which may be in a form of a hologram), wherein the optical arrangement includes a diffractive optical element (herein a phase pinhole), realized using a Spatial Light Modulator (SLM) configured to mimic an actual physical pinhole, while allowing the formation of a three-dimensional representation for a specific point of interest in said object, such that for each scanning position a single hologram or an image is recorded.

Abstract: A new and distinct Pyracomeles cultivar named ‘NCXP1’ is disclosed, characterized by thornless shoots and a compact, dense, spreading plant habit. Plants are non-flowering after 8 years of observation. The new cultivar is a Pyracomeles, suitable for ornamental garden purposes.