Abstract: The subject matter described herein includes methods, systems, and computer readable media for reducing Wi-Fi scanning using cellular network to Wi-Fi access point mapping information. In one exemplary method, a mobile communications device receives Wi-Fi and cellular signals and creates or obtains a database of mappings between Wi-Fi access points and cellular network information. The mobile communications device detects signals from base stations in the cellular network. The mobile communications device determines at least one recommended access point from the data derived from the database. The mobile communications device determines whether any Wi-Fi signals are present. In response to determining that at least one Wi-Fi signal is present, the mobile communications device attempts to connect to the at least one recommended access point.

Abstract: A method of detecting a species, strain or type of bacteria includes mixing a labeled bacteriophage including a label that is detectible via a detection system with a bacterial culture including the species, strain or type of bacteria to which the labeled bacteriophage selectively binds and using the detection system to detect the labeled bacteriophage bound to the species, strain or type of bacteria.

Abstract: Devices and methods for removing tissue, which causes minimal pain or scarring. A hemostatic clamp having two arms with juxtaposeablefaces, can compress tissue between the faces of the arms so as to fuse a portion of the tissue therebetween. A locking mechanism maintains pressure on the arms until the skin is fused to create a skin tab. The unwanted tissue, such as a polydactyl digit, skin tag, or the like, can be excised with the clamp in position. When the locking mechanism is disengaged and the clamp is removed, the fused skin tab inhibits bleeding and the removal of the digit encourages any remaining underlying nerves to withdraw from the area of amputation. A related device can be used as a castration clamp to externally compress testicular-related tissues, such as ductiles, nerves, and blood vessels leading to the testicles, to castrate an animal. The castration clamp provides a quick, bloodless technique that eliminates the need for open wounds, which are subject to infection.

Abstract: Derivatives of the antimalarial agent artemisinin, compositions comprising the derivatives, methods for preparing the derivatives, and their uses in pharmaceutical compositions intended for the treatment of parasitic infections are provided. Methods are provided for the production of artemisinin derivatives via functionalization of positions C7 and C6a, and optionally, in conjunction with modifications at positions C10 and C9, via chemoenzymatic methods. Recombinant cytochrome P450 polypeptides are also provided for use in the methods. The artemisinin derivatives can be used for the treatment of malaria and other parasitic infections, alone or in combination with other antiparasitic drugs.

Abstract: Carcinomas typically invade as a cohesive multicellular unit, a process termed collective invasion. It remains unclear how different subpopulations of cancer cells contribute to this process. We developed three-dimensional (3D) organoid assays to identify the most invasive cancer cells in primary breast tumors. Collective invasion was led by specialized cancer cells that were defined by their expression of basal epithelial genes, such as cytokeratin-14 (K14) and p63. Furthermore, K14+ cells led collective invasion in the major human breast cancer subtypes. Importantly, lumenal cancer cells were observed to convert phenotypically to invasive leaders following induction of basal epithelial genes. Although only a minority of cells within lumenal tumors expressed basal epithelial genes, knockdown of either K14 or p63 was sufficient to block collective invasion. Our data reveal that heterotypic interactions between epithelial subpopulations are critical to collective invasion.

Abstract: A cantilever used in a scanning probe microscope includes a supporting section, a lever section, and a protrusion section, which is a probe. A crystalline carbon composite layer including a crystalline carbon nanomaterial and a metal material, a melting point of which is 420° C. or lower, is deposited on a distal end portion of the protrusion section.

Abstract: Systems, kits, and methods for testing a combustion arrester are disclosed. Systems include an upstream chamber, a downstream chamber, and a combustion arrester between the upstream chamber and the downstream chamber. The upstream chamber includes an ignition port configured to receive an ignition source. And, the upstream chamber defines a convergent duct that converges toward the combustion arrester and terminates at the combustion arrester. The upstream chamber may include a hierarchical series of modular shell sections that define the convergent duct. The downstream chamber may include a series of modular shell sections.

Abstract: A system for elucidating physiological characteristics of laryngeal adductor reflex (LAR) responses in a human or animal subject's larynx's vocal folds (VFs) includes a pressure pulsing component to provide a stable and adjustable pulse of pressure to the larynx, a control system component in functional communication with the pressure pulsing component to control or regulate one or more aspects of the timing, magnitude and number of pulses of pressure delivered by the pressure pulsing component during respiratory cycles, and a respiratory sensor component to detect and/or determine physiological characteristics of the subject's LAR response. The method includes evoking a LAR response in the subject and determining one or more physiological measurements including duration, velocity, and angles of motion of the subject's VFs during the LAR response. The present disclosure provides for enhanced endoscopic field of view of the larynx and delivering stimuli over a wider range of controlled parameters.

Abstract: Articles including a fixing layer and a free layer including a layer including an FePd alloy. The free layer may include a composite layer including a perpendicular synthetic antiferromagnetic (p-SAF) structure. Techniques for forming and using articles including FePd alloy layers or p-SAF structures. Example articles and techniques may be usable for storage and logic devices.

Abstract: A pharmaceutical composition containing a compound of Formula (I) for treating an opioid receptor-associated condition. Also disclosed is a method for treating an opioid receptor-associated condition using such a compound. Further disclosed are two sets of thiazolidinone compounds of formula (I): (i) compounds each having an enantiomeric excess greater than 90% and (ii) compounds each being substituted with deuterium.

Abstract: Methods are described for producing enteroendocrine cells that make and secrete insulin in a mammal by blocking the expression or biological activity of one or more forkhead box O (Foxo) proteins or biologically active fragments or variants thereof.

Abstract: A method of treating vaginal tissue atrophy in a female subject, the method including the steps of engaging an energy delivery element with tissue in or around the subject's vagina; applying energy to the tissue from the energy delivery element; and increasing blood flow to internal vaginal tissue to an increased level above a baseline level of blood flow to the internal vaginal tissue, the increased level of blood flow to the internal vaginal tissue persisting after the applying step ceases. The invention also provides devices for performing this therapy.

Abstract: Apparatus and methods calculate and deliver doses of insulin and optionally glucagon into a subject. Online operation controls delivery of correction doses of insulin automatically in response to regular glucose measurements from a sensor, and offline operation calculates and delivers correction doses based on isolated glucose measurements and information gathered autonomously during preceding online operation. In another aspect, offline operation includes automatically calculating and administering meal doses based on information gathered autonomously during preceding periods of online operation. Both methods include generating relevant control parameters tailored to the individual and continually converged upon and potentially modulated during online operation. The control parameters are employed in real time during periods of offline operation to regulate glucose level without the need for user-provided control parameters such as correction factors and insulin-to-carbohydrate ratios.

Abstract: A pharmaceutical composition comprising an immunoparticle is provided. The pharmaceutical composition comprising a monoclonal secondary antibody immunocomplexed with a primary antibody, wherein said monoclonal secondary antibody is coupled on an outer surface of a particle and wherein said particle is loaded with a pharmaceutical agent.

Abstract: The system and method spatially predict the condensation of water and acid from the flue gas in the condensing heat exchanger installed in fossil power plant flue gas treatment system or similar environment. By modifying the operational conditions, the heat exchanger can control rates and areas of condensations. The system and method adjust either the cooling water temperature or the flowrate ratio of flue gas to cooling water to control the condensation rates of water or acids. The system and method also estimate actual coverage areas to apply for anti-corrosive coating onto the tube or duct surfaces to resist corrosion due to acid condensation. The system and method also optimize or customize condensation rates of water and acids in boiler flue gas under operating conditions given at a power plant.

Abstract: The invention provides a method of manufacturing a stent (12) using a three dimensional (3D) printer. The invention also extends to 3D printed stents and second medical uses of such stents. The invention also extends to electric signals carrying computer-executable instructions adapted to cause a 3D printer to print a stent, computer-readable programs and computer-readable mediums.

Abstract: Disclosed are methods and systems for determining concentrations of a target molecule and a variant thereof in a sample. The sample can comprise or be suspected to comprise a target molecule and at least one variant thereof and is exposed to one or more recognition elements that bind to the target molecule and/or the at least one variant. A signal is detected that is associated with the binding of the target molecule and/or a signal is detected that is associated with the binding of the at least one variant to the one or more recognition elements. The concentration of the target molecule and/or the at least one variant thereof is determined based on the signals. The system can comprise a receiver adapted to receive a sample comprising or suspected to comprise a target molecule and the at least one variant thereof, the receiver comprising one or more recognition elements that bind to one or more epitopes in the target molecule and/or the at least one variant thereof.

Abstract: A trench MOS device with improved single event burnout endurance, applied in the field of semiconductor. The device is provided, in an epitaxial layer, with a conductive type semiconductor pillar connected to a source and a second conductive type current-directing region. Whereby, the trajectory of the electron-hole pairs induced by the single event effect is changed and thus avoids the single event burnout caused by the triggering of parasitic transistors, therefore improving the endurance of the single event burnout of the trench MOS device.

Abstract: A compound of formula (I) includes any forms of tautomer or stereoisomer thereof, wherein the formula (I) is presented as: wherein the definitions of X, R1, and R2 are as specified in the specification hereof. The preparing method and the usage in cancer treatment of such compound are also provided by the present invention.

Abstract: A digital signature protocol achieves the least energy consumption, the fastest signature generation, and the smallest signature among its ECC-based counterparts. The method of authenticating is also immune to side channel attacks aiming elliptical curve operations/exponentiations as well as to weak pseudo random number generators at the signer's side. A security system for authenticating the updating of computer records includes a network of member computers in data communication with each other and calculating an assigned portion of a commitment code used for the authenticating the secure data at the verifier device by completing, among the server computers, a plurality of discrete verification tasks for a single authentication code (R?) associated with an aggregated commitment code (R), aggregating at the verifier device, the aggregated commitment code (R), and verifying the secure data at the verifier device.