Abstract: Compositions and methods are provided herein for the prevention and treatment of cancer, including prostate cancer, breast cancer, and androgen-independent cancer. In one aspect, the present invention provides a composition comprising a niclosamide analog and an antiandrogen drug. In some embodiments, the compositions and methods provided herein inhibit a mutant or splice variant androgen receptor. In particular embodiments, the compositions and methods provided herein reduce the androgen independence of a cancer. Kits are also provided herein.

Abstract: Methods are disclosed for inhibiting esophageal inflammation in a subject, that include administering to the esophagus of the subject with esophageal inflammation a therapeutically effective amount of an extracellular matrix (ECM) hydrogel. Methods are also disclosed for reducing esophageal stricture. Compositions are disclosed that include an esophageal extracellular matrix (ECM) hydrogel.

Abstract: This invention relates, e.g., to a Myocyte-based Flow Assist Device (MFAD) for treating a subject in need of increased flow of a biological fluid, such as venous blood or lymph, comprising a sheath which comprises rhythmically contracting myocytes.

Abstract: The present invention relates to methods of determining if a subject has a decreased risk of suffering from future memory impairment. The methods comprise analyzing at least one plasma sample from the subject to determine a value of the subject's metabolite profile and comparing the value of the subject's metabolite profile with the value of a normal metabolite profile. A change in the value of the subject's metabolite profile, over normal values is indicative that the subject has a decreased risk of suffering from future memory impairment compared to a normal individual.

Abstract: The present disclosure relates to methods for treating or preventing rejection of solid organ transplants by administering prostacyclin (PGI2) or a prostacyclin analog.

Abstract: In a wireless communication system, a transmitter sends a signal in the form of a number of channel blocks, onto some of which is superimposed an authentication signal. A receiver then uses probabilistic methods that take channel fading into account to determine how many blocks include the authorization signal, and then compares this number with a threshold value. This information may then be used by the transmitter to adjust transmission power.

Abstract: An object of the present invention is to provide a novel therapeutic or preventive agent for human T cell leukemia virus type-1 associated myelopathy (HAM) containing an anti-human CC-chemokine receptor 4 (CCR4) antibody or an antibody fragment thereof as an active ingredient, and characterized by the administration and dosage of the antibody or the antibody fragment thereof. The present invention relates to a therapeutic or preventative agent for HAM characterized in that an anti-human CCR4 antibody or an antibody fragment thereof is contained as an active ingredient and the antibody or the antibody fragment thereof is administered at a low dose.

Abstract: Systems, methods, and computer-readable media for context-aware synthesis for video frame interpolation are provided. A convolutional neural network (ConvNet) may, given two input video or image frames, interpolate a frame temporarily in the middle of the two input frames by combining motion estimation and pixel synthesis into a single step and formulating pixel interpolation as a local convolution over patches in the input images. The ConvNet may estimate a convolution kernel based on a first receptive field patch of a first input image frame and a second receptive field patch of a second input image frame. The ConvNet may then convolve the convolutional kernel over a first pixel patch of the first input image frame and a second pixel patch of the second input image frame to obtain color data of an output pixel of the interpolation frame. Other embodiments may be described and/or claimed.

Abstract: Provided is an apparatus for generating data based on generative adversarial networks (GANs), the apparatus including a first generator configured to receive input data and generate a first fake image and a first discriminator configured to receive the first fake image generated by the first generator and a first real image and verify whether an image is fake or real.

Abstract: A semiconductor light-emitting element having an emission peak wavelength of 395 nm or more and 425 nm or less, comprises: a substrate including a first surface and a second surface, at least one surface selected from the group consisting of the first and second surfaces having an uneven region; a semiconductor layer on the first surface; and a multilayer reflective film on the second surface or the semiconductor layer, wherein the multilayer reflective film includes a structure having a plurality of first dielectric films and a plurality of second dielectric films, the first dielectric films and the second dielectric films being alternately stacked.

Abstract: Disclosed herein are a ceramic particle comprising a ceramic core substrate and a conformal coating of a sintering aid film on a surface of the core substrate, wherein the conformal coating includes a plurality of distributed islands of the sintering aid film across the surface of the core substrate; methods for producing the ceramic particle by ALD or MLD; and methods of using the coated ceramic particles in additive manufacturing or in solid oxide fuel cells. In one example, the film may have a thickness of less than three nanometers. The disclosed ceramic particle may be non-reactive with water.

Abstract: An autonomous vehicle can plan a path of the autonomous vehicle at an intersection where cyclists are also present. The autonomous vehicle includes an imaging device and processing circuitry configured to receive information from the imaging device and then identify a position of a cyclist in a traffic intersection based on the information from the imaging device. Additionally, a future path of the cyclist is predicted based on the position of the cyclist in the traffic intersection and a path of the autonomous vehicle is planned based on the predicted future path of the cyclist. Further, it can be determine if the cyclist followed the predicted future path, and the planned path of the autonomous vehicle is updated in response to the cyclist not following the predicted future path.

Abstract: A method for evaluating the breakage strength of first and second cemented surfaces of well cementation under a dynamic load, includes: producing a rock-set cement-casing composite structure sample; clamping the sample between an incident rod and an output rod of a Hopkinson rod, hitting the incident rod with a conical punch to generate incident waves, enabling the incident waves to pass through the sample to generate reflected waves and projected waves, recording dynamic strain signals of incident waves, reflected waves and projected waves, and converting the dynamic strain signals into electrical signals and transmitting the electrical signals to a computer; recording the process and the corresponding time point from breakage starting to a complete breakage of the first and second cemented surfaces by a photographic instrument; obtaining a strain rate time travel curve and a stress-strain curve, and obtaining the corresponding breakage strength by analyzing the curve peak points.

Abstract: An autonomous vehicle configured to autonomously pass a cyclist includes an imaging device and processing circuitry configured to receive information from the imaging device. Additionally, the processing circuitry of the autonomous vehicle is configured to identify a cyclist passing situation based on the information received from the imaging device, and plan a path of an autonomous vehicle based on the cyclist passing situation. The autonomous vehicle also includes a positioning system and the processing circuitry is further configured to receive information from the positioning system, determine if the cyclist passing situation is sufficiently identified, and identify the cyclist passing situation based on the information from the imaging device and the positioning system when the cyclist passing situation is not sufficiently identified based on the information received from the imaging device.

Abstract: A probe and connected system provide ultrasound imaging and optical tomographic imaging of the prostate. A transrectal component carries ultrasound and optical sources and detectors movably connected to a reference element called a probe carrier that provide a reference frame to coregister anatomical and optical tomographic image data.

Abstract: Disclosed are compositions and methods that include or utilize plant growth promoting rhizobacteria (PGPR) for improving growth and health in plants and animals. The compositions and methods include or utilize a plant growth promoting rhizobacteria (PGPR) that expresses a protein associated with pectin metabolism, and a saccharide comprising pectin or a pectin-related saccharide.

Abstract: A method of directly measuring SO2 and other trace gases by configuring an electrochemical cell (ECC) sonde; and an ECC sonde pump inlet filter to remove ozone and other trace gases. Further, calibration and operation procedures for the SO2 and other trace gas ECC sondes are disclosed.

Abstract: A dynamic multi-objective task allocation system within robotic networks that assigns tasks in real-time as they are detected, the system including a sensing device that detects a trigger event, the trigger event being associated with a task to be performed, and transmits a broadcast signal to a designated robotic network, the robotic network including one or more robots, the broadcast signal including information associated with the task to be performed, the trigger event, the task to be performed, and a location where the task is to be performed; and a distribution robot that receives broadcast signal from the sensing device, assigns itself a self-score associated with performing the task, transmits, to one or more receiving robots within the robotic network, a request for submission of an assessment score of each one of the one or more robots, and determines which robot is assigned to perform the task.

Abstract: Described are compounds for targeting proteases, e.g. serine proteases and their use in the diagnostic methods and methods for treatment of respiratory diseases such as cystic fibrosis. The compounds have the structure [H]—[B]-[A]; wherein [H] is a hydrophilic group, [B] is a subsite recognition group and [A] is a binding group; wherein A has the formula: —C(0)—CH2—NR1—COOR2 and wherein [B] has the structure: (i) —[CO—CH2—NR3]m-, or (ii) -[AA1-AA2]- or (iii) -(AA1-C0-CH2NR3)— or (iv) —(CO—CH2—NR3-AA1)- or (v) —(C0—CH2—NR4-AA1-AA3)-.

Abstract: An on-chip supercapacitor constituted by a silicon substrate and a porous carbon layer positioned thereon, the carbon layer including pseudocapacitive materials. The invention also relates to the method for producing the supercapacitor and the porous material.