Patents Assigned to University
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Publication number: 20200014104Abstract: A device for an intelligent robotic antenna is provided. The intelligent robot antenna can comprise a substrate made from a compliant material, a conductive antenna element disposed on the substrate, a sensor that sense environmental conditions around the antenna, an actuator that transforms the antenna, and artificial intelligence software that can determine an optimal structural geometry of the antenna based upon the environmental characteristics surrounding the antenna, and direct the actuator to transform the structural geometry of the antenna to an optimal structural geometry.Type: ApplicationFiled: July 3, 2018Publication date: January 9, 2020Applicant: The Florida International University Board of TrusteesInventor: Stavros Georgakopoulos
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Publication number: 20200010501Abstract: Disclosed are cyclic-di-nucleotide cGAMP analogs, methods of synthesizing the compounds, pharmaceutical compositions comprising the compounds thereof, and use of compounds and compositions in medical therapy.Type: ApplicationFiled: June 11, 2019Publication date: January 9, 2020Applicants: ImmuneSensor Therapeutics, Inc., The Board of Regents of the University of Texas SystemInventors: Boyu ZHONG, Heping SHI, Yuanwei DAI, Qi WEI, Chuo CHEN, Zhijian CHEN, Lijun SUN
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Publication number: 20200009067Abstract: Provided is a formulation and method for increasing bioavailability of an orally administered drug.Type: ApplicationFiled: September 20, 2019Publication date: January 9, 2020Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.Inventors: Amnon HOFFMAN, Abraham J. DOMB, Anna ELGART, Irina CHERNIAKOV
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Publication number: 20200009146Abstract: The invention provides a compound of formula (I): wherein R1, R2, R3, and R4 are as defined herein, ginsenoside Rg2 of structure (II): or a combination thereof, for use in treating or preventing a condition responsive to the induction of autophagy in a brain of a mammal in need thereof.Type: ApplicationFiled: January 25, 2018Publication date: January 9, 2020Applicants: Northwestern University, The United States of America, as Represented by the Secretary, Department of Health & Human Services, University of KansasInventors: Congcong HE, Sui HUANG, Chen WANG, Altea ROCCHI, Juan Jose MARUGAN, Marc FERRER, Samarjit PATNAIK, Yuchi CHEN, Kevin FRANKOWSKI, Frank J. SCHOENEN
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Patent number: 10524689Abstract: The present disclosure provides, in part, methods for high spatiotemporal resolution self-sorted 4D MRI. These methods can be used to improve resolution of abdominothoracic MRI during breathing by facilitating the sorting of information corresponding to individual MRI pulse sequences according to phase within the respiratory cycle. An image of the anatomy for a particular phase within the respiratory cycle is then determined using both information corresponding to the particular phase and high-frequency MR imaging information corresponding to other respiratory phases. This method provides an increase in image resolution by sharing information at high frequencies in k-space, which may be less thoroughly sampled during any particular respiratory phase, between different respiratory phases.Type: GrantFiled: May 19, 2017Date of Patent: January 7, 2020Assignee: Duke UniversityInventors: Ergys Subashi, Jing Cai
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Patent number: 10525026Abstract: A method for administering citrulline to a patient during surgery without filtration of the hemolysis.Type: GrantFiled: June 29, 2016Date of Patent: January 7, 2020Assignee: Vanderbilt UniversityInventors: Marshall L. Summar, Frederick E. Barr
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Patent number: 10526622Abstract: The present disclosure relates to the technical field of biochemical engineering and particularly discloses a preparation method for (R)-3-hydroxyl-5-hexenoate. In the method of the present disclosure, the (R)-3-hydroxyl-5-hexenoate is prepared by catalytic reduction of 3-carbonyl-5-hexenoate by ketoreductase with 3-carbonyl-5-hexenoate as the substrate. The amino acid sequence of ketoreductase is shown in SEQ ID NO.1. In the present disclosure, the (R)-3-hydroxyl-5-hexenoate having a very high chiral purity is obtained by asymmetric reduction by ketoreductase as the biocatalyst. The present disclosure has the advantages of easy operation, mild reaction conditions, high reaction yield and good practical industrial application value.Type: GrantFiled: January 14, 2018Date of Patent: January 7, 2020Assignee: Fudan UniversityInventors: Fener Chen, Zedu Huang, Ge Meng, Minjie Liu, Zhining Li, Zexu Wang, Haihui Peng, Fangjun Xiong, Yan Wu, Yuan Tao
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Patent number: 10528396Abstract: A system and method of scheduling tasks include receiving inputted data task variables for a private CDC and a plurality of public clouds; initializing parameters for a plurality of representative entities in a cluster of entities; determining a fitness level of each representative entity in the cluster of entities; updating one or more task scheduling parameters for a given number of time slots based on the parameters for the plurality of representative entities and the fitness level of each representative entity; determining a total number of data tasks to be dispatched to the private CDC and the plurality of public clouds based on an iteration result of a final time slot for the given number of time slots for a global best position; and updating the data task variables using the total number of data tasks to be dispatched.Type: GrantFiled: November 14, 2016Date of Patent: January 7, 2020Assignee: King Abdulaziz UniversityInventors: Ahmed Chiheb Ammari, Haitao Yuan, Jing Bi, Mengchu Zhou, Yusuf Al-Turki, Abdullah Abusorrah
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Patent number: 10529061Abstract: Systems and methods of producing medical images of a subject are disclosed herein. In one embodiment, structural data and vascular data are acquired from a region of interest in the subject. A filter is generated using structural image data acquired from a second layer and blood flow image data received from a first layer in the region of interest. The filter is applied to vascular image data acquired from a second, deeper layer in the region of interest to form an image of the second layer having reduced tailing artifacts relative to the unfiltered vascular image data.Type: GrantFiled: August 12, 2016Date of Patent: January 7, 2020Assignee: University of WashingtonInventors: Ruikang K. Wang, Anqi Zhang
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Patent number: 10524411Abstract: Described is a high-speed transplanting mechanism that includes an angle-adjusting device about an angle of a duckbill entering soil, the mechanism comprising a rear arm, a front arm, a restoring spring, a control wire, a control wire sleeve and a control adjuster. The front arm is hinged on the mounting base of the planting device, the rear arm is hinged on the duckbill planting device, and the another end of the rear arm and the front arm are axial sliding connection. The control adjuster comprises an adjuster body and a handle fixed on the adjuster body. The restoring spring is positioned between the first limit plate on the rear arm and the second limit plate on the front arm. The end of the control wire is fixed on the second limit plate and, in turn, the other end of the control wire passes through the first limit plate, the restoring spring, the second limit plate and the control wire sleeve, and finally fixed to the adjuster body.Type: GrantFiled: January 12, 2018Date of Patent: January 7, 2020Assignee: Jiangsu UniversityInventors: Lili Dong, Lvhua Han, Zhen Wang
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Patent number: 10526441Abstract: A method of fabricating polypyrrole-coated silver particles having a core-shell structure via in-situ oxidative polymerization using silver nanoparticles and pyrrole monomers in the presence of an oxidizing agent. A surface enhanced Raman scattering (SERS) active substrate comprising the polypyrrole-coated silver particles is also disclosed. The surface enhanced Raman scattering (SERS) active substrate is demonstrated to facilitate the detection and measurement of surface enhanced Raman scattering (SERS) spectra of analytes with increased Raman signal intensity.Type: GrantFiled: January 23, 2019Date of Patent: January 7, 2020Assignee: King Fahd University of Petroleum and MineralsInventors: Umair Baig, Mohammad Kamal Hossain
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Patent number: 10529906Abstract: System for quantum energy storage can include a quantum information engine including topological insulator having at least one edge. A coherence capacitor can include nuclei of atoms within the topological insulator, and each nucleus can have a spin direction. An energy source can be electrically connected to the topological insulator and configured to supply a current along the at least one edge of the topological insulator. The current can interact with at least one nucleus of the nuclei to flip a spin direction of the at least one nucleus. Methods for quantum energy storage, systems and methods for storing and using quantum energy, quantum information engines, and quantum heat engines are also disclosed.Type: GrantFiled: April 3, 2017Date of Patent: January 7, 2020Assignees: Lockheed Martin Corporation, Sabanci UniversityInventors: Edward Henry Allen, Inanc Adagideli
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Patent number: 10524663Abstract: Methods and apparatus for assessing and correcting phase variations and motion artifacts in a coherent tomogram of a sample. Coherent techniques are used scan a broadband optical beam across a sample in a specified scan pattern and to acquire a cube of complex data constituting a full tomogram. Generalized motion of the sample is then quantified based at least on a phase variation measured during the course of scanning the broadband optical beam in the specified scan pattern. Generalized motion includes both actual motion and apparent motion due to organized variation of some physical parameter such as temperature. Intensity structure of speckle imaged during the course of coherently acquiring the full tomograpm may be used to correct for motion of the sample in a plane transverse to a depth axis along the incident beam.Type: GrantFiled: June 17, 2016Date of Patent: January 7, 2020Assignee: The Board of Trustees of the University of IllinoisInventors: Stephen A. Boppart, Paul Scott Carney, Nathan Shemonski
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Patent number: 10529979Abstract: The present disclosure relates to a method for making a lithium-ion battery anode. The method comprises the steps of scratching off a carbon nanotube array to obtain a plurality of carbon nanotubes, adding the plurality of carbon nanotubes into a solvent, and ultrasonically dispersing the solvent to make the plurality of carbon nanotubes form a three-dimensional network-like structure; adding a titanium salt into the solvent, wherein the titanium salt hydrolyzes to form a plurality of titanium dioxide particles, and the plurality of titanium dioxide particles are adsorbed on surfaces of the plurality of carbon nanotubes; and separating the nanotube three-dimensional network structure from the solvent to form a precursor, and drying the precursor to form a titanium dioxide-carbon nanotube composite film.Type: GrantFiled: February 8, 2018Date of Patent: January 7, 2020Assignees: Tsinghua University, HON HAI PRECISION INDUSTRY CO., LTD.Inventors: Kun-Lei Zhu, Kai Liu, Jia-Ping Wang, Kai-Li Jiang, Shou-Shan Fan
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Patent number: 10524525Abstract: The present invention relates to bodysuits for use as personal protective equipment comprising a torso portion comprising a front side; a back side including a sealable port through which a wearer can enter and exit the bodysuit when donning or doffing the bodysuit, respectively; a waist region; a neck opening; a pair of upper limb openings; and a pair of lower limb openings; two arm portions each extending from one of the upper limb opening; and two leg portions each extending from one of the lower limb opening and methods for the removal of such body suits.Type: GrantFiled: December 14, 2015Date of Patent: January 7, 2020Assignee: The Johns Hopkins UniversityInventors: Youseph Yazdi, Melody Tan, Matthew Petney, William Alexander LeMay Patterson, Siavash Parkhideh, Jill Andrews, Patience Osei, Soumyadipta Acharya, Chandrakant Ruparelia, HarshadKumar Sanghvi, Timothy Patrick Harrigan, Nahyun Kate Cho, Qian Liu, Brandon Craft, Paul Fearis, Sami Messai, Brian Ma, Meagan Hawes, Reeve Ilse Heinis, Jason Onslow Leroy Johnson, Erin Reisfeld, Arjun Shailesh Vachhani, Timothy Campbell, Neil Rens, Madeleine Clegg, Elizabeth Anne Stokley, Jessica Jeang, Christopher Chiang, Willibrord Shasha, Bailey Topper, Kimberly Ashman, Michael Parlato
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Patent number: 10525075Abstract: Compounds and compositions for the transient expression of exogenous telomerase activity in a cell are provided. The compounds and compositions, which relate to a ribonucleic acid coding for a telomerase reverse transcriptase, are useful in the extension of telomeres in cells needing such treatment. Such cells include, for example, cells that contain shortened telomeres and cells from subjects that may benefit from telomere extension, for example subjects that suffer from, or are at risk of suffering from, age-related or other illnesses. Also provided are methods of extending telomeres through the administration of the provided compounds and compositions to animal cells, either in vitro or in vivo, and kits including the compounds or compositions and instructions for use.Type: GrantFiled: February 22, 2014Date of Patent: January 7, 2020Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: John Ramunas, Eduard Yakubov, Helen M. Blau, John Cooke
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Patent number: 10525173Abstract: The present disclosure discloses a hybrid implant system for fixing and repairing orthopedic fracture and a manufacturing method therefor. The hybrid implant system comprises an implant body having holes on both ends and a locking part configured for attaching the implant body to a broken bone through the holes. The hybrid implant system further comprises a healing assembly made from a material promoting healing of the bone. The implant body has at least one window on a side, the at least one window is aligned with a broken location of the bone, and the healing assembly is inserted into the window in a self-locking manner towards an interior of the implant body.Type: GrantFiled: January 18, 2018Date of Patent: January 7, 2020Assignee: The Chinese University of Hong KongInventors: Ling Qin, Yuk Sun Cheng, Ning Tang, Wing Ho Chau
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Patent number: 10525281Abstract: Provided is a spacer for ionizing radiation therapy, which can be easily disposed in a living body, does not require abdominal surgery for removing the disposed spacer after radiation therapy, and can effectively separate a tissue to be treated from other tissues. The spacer for ionizing radiation therapy includes a fiber assembly obtained by three-dimensionally entangling a fibrous material formed of a biocompatible synthetic polymeric material. Specifically, the spacer has a thickness of 1 mm to 100 mm.Type: GrantFiled: October 28, 2010Date of Patent: January 7, 2020Assignees: National University Corporation Kobe University, Kanai Juyo Kogyo Co., LTD., Alfresa Pharma CorporationInventors: Takumi Fukumoto, Tsutomu Obata, Yoshitaka Tagami, Eiichi Uemura, Michiko Manabe
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Patent number: 10526579Abstract: The following disclosure generally relates to methods of culturing podocytes in vitro. The cultures can be used for drug screening (such as medium or high throughput drug screening), and for studying molecular pathways involved in glomerular diseases. The disclosure also provides methods for analyzing the healthiness of podocytes in a cell culture. The disclosure also relates to diagnosis of kidney diseases.Type: GrantFiled: March 10, 2014Date of Patent: January 7, 2020Assignee: Rush University Medical CenterInventors: Tristan Hays, Jochen Reiser, Vineet Gupta
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Patent number: 10525125Abstract: Mixed allergen compositions of one, two or more different allergens are provided. In some instances, the mixed allergen compositions include: a nut allergen; an animal allergen; and at least one of: a non-nut plant allergen; a biotic agent; and a vitamin. Also provided are methods of administering the mixed allergen compositions to a subject. The mixed allergen compositions find use in a variety of applications, including health maintenance, immune balance, gut balance, immune support, health improvement and therapeutic applications.Type: GrantFiled: October 26, 2018Date of Patent: January 7, 2020Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventor: Kari C. Nadeau