Abstract: A propulsion system for an aircraft or other vehicle can include an electric motor with a rotor and a stator. A cooling arrangement for the electric motor can include one or more of: a heat sink that is disposed within an internal area of the motor and that supports, within the internal area, one or more power-electronic components for operation of the electric motor; and a plurality of flow channels that are formed along at least one of the rotor and the stator. The flow channels can be arranged to route ambient air past the at least one of the rotor and the stator during operation of the aircraft or other vehicle.

Abstract: The present disclosure provides the use of fratricide-resistant chimeric antigen receptor T (CAR-T) cells targeting antigens expressed by T cell malignancies.

Abstract: An encapsulation system and method including a solution having a first system with a first rate of removal, a second system with a second rate of removal, and a material soluble in the first system, but not soluble in the second system. The first rate of removal is quicker than the second rate of removal, and removal of the first system from the solution creates a concentration of the second system and the material migrates around the second system. Thus, the material creates a shell around the second system, generating a capsule with a shell of the material and a core of the second system. Such material may include a polymer, copolymer, or block copolymer, while the second system is poor solvent for the material, such as hexadecane or Oil Red O. The first system is a good solvent for the material and is readily removable from solution via evaporation during processes like electrospraying.

Abstract: The present invention provides a chimeric antigen receptor (CAR) that recognizes B7-H3 (CD276), as well as methods of use in the treatment of diseases and disorders.

Abstract: Disclosed is a method for 3D building extraction, comprising: extracting building footprints from one or more stereo images for a building; determining, from rational polynomial coefficient of the stereo images, first height estimation of the extracted building footprints; obtaining, from multi-temporal SAR images for the building, scatters with stable attributes; determining second height estimation for the determined scatters; and combining the first height estimation and the second height estimation to generate a fused height for each of the extracted building footprints.

Abstract: A method for determining the presence or amount of a target nucleic acid sequence in a sample, uses magnetic particles loaded with a probe and polystyrene particles loaded with a probe, in particular a different probe, for directly or indirectly detecting the presence or amount of the target nucleic acid sequence which is in particular indicative of a disease. The methods of the present invention allow for determining target nucleic acid sequences even in low abundance and in complex samples with advantageous sensitivity and, thus, represent promising approaches which can in particular be used in the diagnosis of several diseases and health conditions. A kit comprising a loaded magnetic particle and a loaded polystyrene particle is provided and can be used for the methods of the present invention, in particular for diagnosis or prognosis of a disease in a subject such as a human.

Abstract: Methods are disclosed for treating cell components, cells, organelles, organs, and/or tissues with acoustic energy, electromagnetic energy, static or alternating electric fields, and/or static or alternating magnetic fields in the presence or absence of exogenous particulate agents for therapeutic applications.

Abstract: In some examples, a device includes an integrated circuit and two or more computational units configured to process respective stochastic bit streams in accordance with respective input clocks. Each of the stochastic bit streams comprises sequential sets of data bits, each of the sets of data bits representing a numerical value based on a probability that any bit in the respective set of data bits is one. The respective input clocks for each of the two or more computational units are unsynchronized.

Abstract: A method of designing a logic circuit with data-dependent delays is performed using an electronic design automation system. The logic circuit includes logic paths from logic inputs to at least one logic output. The method includes: obtaining an initial circuit design; specifying respective delays for multiple logic paths in the initial circuit design such that at least some of the outputs switch at different times within a clock cycle for different combinations of logic input levels; and forming a second circuit design having the specified respective delays along the respective logic paths by adding delay elements to the initial circuit design based on the specified respective delays.

Abstract: A lightweight micro-closed-pore corundum composite refractory and a method preparing the same, wherein raw materials of the refractory comprise 95-99 parts by weight of ?-Al2O3 micro-powder and 1-5 parts by weight of dolomite clinker; and additives of the refractory comprise 2-15 parts by weight of nano alumina sol, 5-15 parts by weight of a carbohydrate polymer, and 30-50 parts by weight of an organic alcohol. and the lightweight micro-closed-pore corundum composite refractory is prepared by: mixing and wet grinding the raw materials and the additives to obtain a slurry; placing the slurry in a mold, keeping the mold at 15-25° C. for 6-12 hours and then keeping the mold at 60-90° C. for 6-12 hours, then demolding; drying a demolded green body at 110-200° C. for 24-36 hours, and keeping the green body at 1800-2000° C. for 2-5 hours. A method preparing a lightweight micro-closed-pore corundum composite refractory is also provided.

Abstract: Methods and systems for single beam scanning capable of imaging the surface of a spherical body of arbitrary radius of curvature are provided. The spherical imaging methods and systems utilize one or more off-axis parabolic (OAP) mirror to perform a geometrical transformation of the spherical surface to a flat rectilinear imaging coordinate grid such that the single scanning beam maintains a normal incidence across the curved field of view of the spherical body. The imaging methods and systems project the spherical surface to a Cartesian plane and then the remapped surface is rapidly imaged by raster-scanning an illumination beam in the rectangular coordinate such that the OAP mirror produces a rectilinear image of the target. The imaging of the spherical surface is accomplished while maintaining the target, illumination source, and detector in a stationary position. The imaging systems and methods may utilize a single source and a single detector, and may incorporate a THz illumination source.

Abstract: An information terminal which allows an increase in a manufacturing cost to be suppressed is disclosed. A ticket printer is held above a paper sheet processing device. A guide by which a ticket or the like ejected from a ticket ejection slot of the ticket printer is guided and an insertion slot of a paper sheet processing device are held in a state in which the guide and the insertion slot have a predetermined angle. A ticket or the like which is printed by the ticket printer is supplied from the ticket ejection slot of the ticket printer via the guide to an opening part of a bezel. On the other hand, a paper sheet which is inserted into the paper sheet processing device is supplied from the opening part of the bezel to the insertion slot of the paper sheet processing device.

Abstract: A method for residual oil recovery from oil reservoirs, and diagnostic tests for determining its efficiency using a single well are described. The method includes injecting oil into a well in a reservoir that has been previously waterflooded or an oil reservoir or zone of an oil reservoir which contains immobile oil at the time of discovery, and extracting the oil by waterflooding the charged zones by placing the injection well in production. The target zone from which oil is recovered may be increased by following injection of oil with injection of water to push an oil bank which grows in volume as a function of distance of propagation, because of the effect of waterflooding on residual oil. The well may then be placed in production and the oil bank volume will continue to increase in volume as it returns to the well, again because of the waterflooding effect. The oil bank is then produced at the surface.

Abstract: Two related methods of fitting a three dimensional model, and a method of performing facial recognition, are disclosed. One method comprises estimating and refining geometric information using image landmarks on an object in a two dimensional image. The other method comprises estimating and refining photometric information of the object in the two dimensional image. Furthermore, a method of performing image recognition is provided.

Abstract: A compound comprising, in combination: a cell surface binding ligand or internalizing factor, such as an IL-13R?2 binding ligand; at least one effector molecule (e.g., one, two, three or more effector molecules); optionally but preferably, a cytosol localization element covalently coupled between said binding ligand and said at least one effector molecule; and a subcellular compartment localization signal element covalently coupled between said binding ligand and said at least one effector molecule (and preferably with said cytosol localization element between said binding ligand and said subcellular compartment localization signal element). Methods of using such compounds and formulations containing the same are also described.

Abstract: A photovoltaic cell includes a junction, formed from an n-type semiconductor material and a p-type semiconductor material, a trench, opening toward the light-incident side of the junction, for trapping reflected light, and two photon conversion layers. A first photon conversion layer, arranged at the light-incident side of the junction, converts photons from a higher energy to a lower energy suitable for absorption by the semiconductor material, and a second photon conversion layer, arranged at the opposite side of the junction, converts photons from a lower energy to a higher energy suitable for absorption by the semiconductor material.

Abstract: Provided herein are several methods for selecting agents that bind to transmembrane receptors in a conformationally-selective way. In some embodiments, the method may comprise producing: a transmembrane receptor in an active conformation; and said transmembrane receptor in an inactive conformation and using cell sorting to select, from a population of cells comprising a library of cell surface-tethered extracellular capture agents, cells that are specifically bound to either the transmembrane receptor in its active conformation or the transmembrane receptor in its inactive conformation, but not both. In other embodiments, the method may comprise: contacting a GPCR with a population of cells that comprise a library of surface-tethered extracellular proteins; labeling the cell population with a conformationally-specific binding agent, e.g., a G-protein or mimetic thereof; and using cell sorting to select from the cell population cells that bind to the agent.

Abstract: The invention provides efficient searching with fuzzy criteria in very large information systems. The technique of the present invention uses the Pigeonhole Principle approach. This approach can be utilized with different embodiments, but the most effective realization would be to amplify some already given intrinsic approximate matching capabilities, like those in the FuzzyFind method [1][2]. Considering the following problem, data to be searched is presented as a bit-attribute vector. The searching operation includes finding a subset of this bit-attribute vector that is within particular Hamming distance. Normally, this search with approximate matching criteria requires sequential lookup for the whole collection of the attribute vector. This process can be easily parallelized, but in very large information systems this still would be slow and energy consuming.

Abstract: A probe for detecting bacteria and/or fungi in vitro and in vivo is provided, the probe having a core and a plurality of probe elements; each probe element within the plurality of probe elements extending from the core and having a fluorophore and a binding moiety, wherein the binding moiety is a bacteria binding moiety and selectively binds to bacteria and/or to fungi and not to animal cells. Methods of use of the probe and kits comprising the probe are also provided.

Abstract: A lighting device (e.g. LED driver) includes digital dimming, configuration and firmware updating via wireless communication circuitry and associated volatile memory (e.g., SRAM). A power stage converts AC mains input into a DC bus voltage, and further converts the DC bus voltage into output current for driving a load. A power distribution circuit generates a regulated DC voltage based on the DC bus voltage. A wireless interface circuit is linked to a wireless communications network (e.g., NFC), and configured to receive device configuration data during at least first operating conditions when the regulated DC voltage is unavailable, and further to receive dimming control data during second operating conditions when the regulated DC voltage is available. A controller generates gate driving signals for regulating the output current from the power stage, said gate driving signals generated based at least in part on the device configuration data and the dimming control data.