Patents Assigned to University
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Patent number: 10494394Abstract: The invention is directed to platinum(II) complexes comprising dithiocarbamates and methods for treating cancer using these complexes.Type: GrantFiled: November 29, 2018Date of Patent: December 3, 2019Assignee: King Fahd University of Petroleum and MineralsInventors: Anvarhusein A. Isab, Muhammad Altaf, Muhammad Ali Ehsan, Khalid Omer
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Patent number: 10492749Abstract: A device and methods for performing a simulated CT biopsy on a region of interest on a patient. The device comprises a gantry configured to mount an x-ray emitter and CT detector on opposing sides of the gantry, a motor rotatably coupled to the gantry such that the gantry rotates horizontally about the region of interest, and a high resolution x-ray detector positioned adjacent the CT detector in between the CT detector and the x-ray emitter.Type: GrantFiled: May 3, 2006Date of Patent: December 3, 2019Assignee: The Regents of the University of CaliforniaInventors: John M. Boone, Thomas R. Nelson
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Patent number: 10497113Abstract: Embodiments disclose a method performed by at least one processor for processing a plurality of x-ray projection images of a subject, the method comprising a plurality of operations including reconstructing the projection images to yield a volume reconstruction; segmenting the reconstructed volume by assigning a material type to each voxel; estimating a first set of scatter images corresponding to a subset of the projection images by calculating probabilistic predictions of interactions of x-rays with the subject and applying a low pass spatial filter to the scatter images; estimating a second set of scatter images corresponding to projection images not included in the subset, based on the first set of scatter images; and subtracting, for each projection image, the corresponding scatter image to yield a corrected projection image.Type: GrantFiled: December 18, 2014Date of Patent: December 3, 2019Assignees: Elekta AB (publ), University Health NetworkInventors: Marcus Hennix, Hakan Nordstrom, Markus Eriksson, Jonas Adler, David Jaffray, Gregory Bootsma, Frank Verhaegen, Bjorn Nutti
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Patent number: 10494596Abstract: A method of microbial electrosynthesis using co-cultures is disclosed. In particular, the invention relates to a method of microbial electrosynthesis utilizing a microbial strain capable of electron uptake from an electrode to produce hydrogen or formate in co-culture with a microbial production strain, such as a methanogen, acetogen, or other microorganism capable of synthesizing valuable products from carbon dioxide and hydrogen or formate.Type: GrantFiled: December 9, 2016Date of Patent: December 3, 2019Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Joerg S. Deutzmann, Alfred Michael Spormann
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Patent number: 10494395Abstract: In one aspect, cobalt complexes are described herein. In some embodiments, such cobalt complexes employ bis(phosphine) or bis(imine) ligand and are operable as catalysts for borylation of arenes and aromatic heterocycles.Type: GrantFiled: December 9, 2014Date of Patent: December 3, 2019Assignee: The Trustees of Princeton UniversityInventors: Paul J. Chirik, Scott Semproni, Jennifer Obligacion, Margaret Scheuermann
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Patent number: 10493061Abstract: The present invention presents 2-(acylamino)imidazoles with therapeutic activity, including selective activity against cancer cells, and compositions comprising them. Methods of using and preparing the 2-(acylamino)imidazoles are also presented.Type: GrantFiled: September 16, 2016Date of Patent: December 3, 2019Assignees: Curza Global, LLC, University of Utag Research FoundationInventors: Ryan E. Looper, Rachel M. Vaden, Joseph B. Gibbons, Justin M. Salvant, Anne V. Edwards, Matthew S. Sigman, Bryan E. Welm
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Patent number: 10492508Abstract: The present invention provides a method for oil extraction from dehydrated Euphausia superbas, which is related to the field of food biotechnology. The method combines a low temperature and low oxygen heat pump dehydration system with a microwave-assisted frozen-blasting dehydration system for Euphausia superba dehydration, resulting in formation of a large number of micro porous structures in dehydrated Euphausia superbas that is good for subsequent oil extraction. The dehydration and extraction process can be separated in the present invention. The low temperature and low oxygen heat pump dehydration system may be installed in shrimp boats to dehydrate Euphausia superbas before transportation so as to increase the effective payloads of shrimp boats. The extraction process of subcritical fluid assisted with ultrasonic operation is carried out under low temperature and low oxygen conditions, therefore the oxidation of active ingredients is avoided to a large extent.Type: GrantFiled: May 16, 2017Date of Patent: December 3, 2019Assignee: Jiangnan UniversityInventors: Yuanfa Liu, Dewei Sun, Jinwei Li, Peirang Cao
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Patent number: 10493426Abstract: A method of preparing a graphene-metal chalcogenide porous material is provided. The method includes providing a dispersion comprising graphene oxide; adding a metal precursor and a chalcogenide precursor to the dispersion to form a mixture; heating the mixture under hydrothermal conditions to form a gel; and freeze drying the gel to obtain the graphene-metal chalcogenide porous material. A graphene-metal chalcogenide porous material prepared by the method, and use of the material in water treatment, energy storage, fire proofing, batteries or supercapacitors are also provided.Type: GrantFiled: January 9, 2015Date of Patent: December 3, 2019Assignee: Nanyang Technological UniversityInventors: Hua Zhang, Hengchang Bi, Bo Chen, Qinglang Ma
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Patent number: 10492882Abstract: Stereotactic systems and implantation methods that can be designed for use with a specific species and further customized for use with an individual within the species are provided. The stereotactic system can include an implant jig that can model a tissue or organ in which a target tissue area is located. A neurocap can be coupled to the implant jig for pre-planning and pre-placement of implants. A stencil can be used to determine the location for placement of the neurocap on the individual, so that the implants can be precisely targeted at the desired location. Pre-surgical information and data can be obtained from an individual and used to customize components of a stereotactic system, which can improve accuracy of implant placement.Type: GrantFiled: June 13, 2017Date of Patent: December 3, 2019Assignees: The Florida International University Board of Trustees, The Regents of the University of CaliforniaInventors: Timothy Allen, Bruce McNaughton, Meifung Su, Leila Mangan Allen
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Patent number: 10493170Abstract: Conjugates are provided containing a graphene quantum dot, a targeting moiety, and an active agent. The conjugates can be used to provide one or more therapeutic, prophylactic, or diagnostic effects to a subject in need thereof. The subject can be a cancer patient and the active agent an anti-cancer agent. The graphene quantum dots can have an average particle size of about 1-20 nm and a monodisperse size distribution. The size distribution can have a span about 1 or less and/or a coefficient of variance of about 0.5 or less. Methods of making the conjugates are provided. The methods can include conjugating the targeting moiety to the GQD using a reactive coupling group. Methods of treating, preventing, and/or diagnosing a disease or disorder in a patient in need thereof by administering the conjugates are provided.Type: GrantFiled: June 23, 2015Date of Patent: December 3, 2019Assignee: University of South FloridaInventors: Yiru Qin, Shu-Feng Zhou
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Patent number: 10494619Abstract: Mutant mammalian RPE65 proteins and portions thereof, and nucleic acids encoding the mutants, for use in treating a condition related to retinal degeneration in a subject, the mutant mammalian RPE65 proteins or portions thereof having isomerohydrolase activity. A gene therapy method of treating a condition related to retinal degeneration in a mammalian subject in need of such treatment, comprising administering to the subject a therapeutically-effective amount of a vector comprising a nucleic acid encoding a mutant mammalian RPE65 protein or a portion thereof. A method of treating a condition related to retinal degeneration in a subject in need of such treatment, comprising administering to the subject a therapeutically-effective amount of at least one of a mutant mammalian RPE65 protein or a portion thereof.Type: GrantFiled: July 27, 2015Date of Patent: December 3, 2019Assignee: The Board of Regents of the University of OklahomaInventors: Jian-Xing Ma, Yusuke Takahashi, Gennadiy Moiseyev
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Patent number: 10494699Abstract: The invention provides a method of refining aluminum alloy, which is characterized in that aluminum-based nanometer quasicrystal alloy is used as an aluminum alloy refiner to refine the aluminum alloy; the aluminum-based nanometer quasicrystal alloy does not comprise Si, Fe or Cr; the aluminum-based nanometer quasicrystal alloy consists of (1) Al; (2) Mn and (3) La and/or Ce. The refiner selected in the invention is rare earth-containing alloy which has a strong refinement ability on the aluminum alloy, and is nanometer quasicrystal; after adding the rare earth-containing alloy to melt, the element distribution of the rare earth-containing alloy is more uniform than that of traditional alloy; and nanometer quasicrystal particles substantially increase the number of heterogeneous nucleation particles and improve the grain refinement effect of the aluminum alloy.Type: GrantFiled: March 16, 2016Date of Patent: December 3, 2019Assignees: CITIC DICASTAL CO., LTD., Hebei University of TechnologyInventors: Lisheng Wang, Yongning Wang, Zhihua Zhu, Chunhai Liu, Changhai Li, Lateng A, Zhendong Zhang, Bangwei Bai, Weimin Zhao, Zhifeng Wang
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Patent number: 10496914Abstract: Devices and methods for detecting credit card skimmers are provided herein. A device can include a printed circuit board having a pattern of electrical traces on its surface, and a computer readable medium comprising instructions that cause a processor to direct an electrical voltage to a trace and detect an electrical current between two points of the trace. A gap can be disposed between the two points across which a voltage is applied in order to detect a magnetic reader. A count of the detected magnetic readers within a credit card reading device may be indicative of the presence of a credit card skimmer.Type: GrantFiled: October 29, 2018Date of Patent: December 3, 2019Assignee: University of Florida Research Foundation, IncorporatedInventors: Walter N. Scaife, Patrick G. Traynor, Christian Peeters
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Patent number: 10493131Abstract: The subject invention provides methods for recruitment of bone marrow-derived cells, including bone marrow-derived endothelial cells (BMDEC), and increasing their function by administration of relaxin. The methods of the invention can be used in, for example, treating conditions amenable to treatment by recruitment of bone marrow-derived cells, such as BMDEC and bone marrow-derived angio-osteogcnic progenitor cell.Type: GrantFiled: August 30, 2012Date of Patent: December 3, 2019Assignee: University of Florida Research Foundation, IncorporatedInventors: Kirk P. Conrad, Mark S. Segal
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Patent number: 10497633Abstract: The present invention provides electronic systems, including device arrays, comprising functional device(s) and/or device component(s) at least partially enclosed via one or more fluid containment chambers, such that the device(s) and/or device component(s) are at least partially, and optionally entirely, immersed in a containment fluid. Useful containment fluids for use in fluid containment chambers of electronic devices of the invention include lubricants, electrolytes and/or electronically resistive fluids. In some embodiments, for example, electronic systems of the invention comprise one or more electronic devices and/or device components provided in free-standing and/or tethered configurations that decouple forces originating upon deformation, stretching or compression of a supporting substrate from the free standing or tethered device or device component.Type: GrantFiled: March 15, 2013Date of Patent: December 3, 2019Assignee: The Board of Trustees of the University of IllinoisInventors: John A. Rogers, Sheng Xu, Jonathan A. Fan, Lin Jia
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Patent number: 10499310Abstract: Aspects of the disclosure provide a wireless node in a wireless network with a grid topology for routing a message. The wireless node includes circuitry configured to receive a message including a destination node identification number, calculate a destination column and a destination row based on the destination node identification number, determine a next hop address based on the destination column and the destination row, and transmit the message including the next hop address to a next hop node.Type: GrantFiled: October 24, 2018Date of Patent: December 3, 2019Assignee: King Fahd University of Petroleum and MineralsInventors: Anas Abdulwahid Al-Roubaiey, Tarek R. Sheltami, Ashraf S. Hasan Mahmoud
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Patent number: 10499086Abstract: The present application discloses video data encoding and decoding methods and apparatuses, so as to conveniently perform data encoding and decoding on video data. The method includes: arithmetic encoding, where the arithmetic encoding includes: obtaining a binary symbol of image data; and if the binary symbol is a most probable symbol (MPS), updating a first encoding interval corresponding to the MPS in a logarithm domain, and if the first updated encoding interval is less than a preset range of an arithmetic encoding interval, performing normalization processing on the first encoding interval in the logarithm domain; or if the binary symbol is a least probable symbol (LPS), updating a second encoding interval corresponding to the LPS in an original number domain, and performing normalization processing on the second encoding interval in the original number domain.Type: GrantFiled: March 22, 2017Date of Patent: December 3, 2019Assignees: Tsinghua University, Huawei Technologies Co., Ltd.Inventors: Quanhe Yu, Xiaozhen Zheng, Jianhua Zheng, Yun He
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Patent number: 10493233Abstract: An apparatus for guiding the migration of cancer and other cells includes a reservoir device, a cover, a tube, a nanofiber structure, and a lock device. The reservoir device defines a reservoir having an open top. The cover is configured for removable installation over the open top of the reservoir. The tube has a proximal end portion reaching into the reservoir. The nanofiber structure communicates an inlet port in the tube with the reservoir. The lock device interlocks the tube with the reservoir device, and also interlocks the nanofiber structure with the reservoir device.Type: GrantFiled: June 5, 2019Date of Patent: December 3, 2019Assignee: Duke UniversityInventors: Nassir Mokarram-Dorri, Ravi Bellamkonda, Barun Brahma, James Leo Pokorney, Jack Cabell Griffis, III, Donald Kenneth Griffin, II
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Patent number: 10498358Abstract: A data encoder including a preprocessor configured to divide a data stream into a plurality of sub data blocks; a plurality of meta data generators each configured to generate meta data from one of the plurality of sub data blocks; and a plurality of data compressors each configured to compress one of the plurality of sub data blocks according to the meta data.Type: GrantFiled: November 6, 2018Date of Patent: December 3, 2019Assignees: SK hynix Inc., Seoul National University R&DB FoundationInventors: Jiwoong Choi, Boyeal Kim, Hyun Kim, Hyuk Jae Lee, Junseo Lee, Changmin Kwak, Youngdoo Song
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Patent number: 10493431Abstract: A catalytic nanoparticle can include a nanodiamond core, a thin-layer polymeric film applied to an outer surface of the nanodiamond core, and a catalyst immobilized at an outer surface of the thin-layer polymeric film. The nanoparticles can also be used in connection with a transducer to form a sensor. A method of catalysis can include contacting the catalytic nanoparticle with a reactant in a reaction area. The reactant can be capable of forming a reaction product via a reaction catalyzed by the catalyst. The method of catalysis can also include facilitating a catalytic interaction between the catalytic nanoparticle and the reactant.Type: GrantFiled: August 30, 2017Date of Patent: December 3, 2019Assignee: University of Utah Research FoundationInventors: Jennifer S. Shumaker-Parry, Arthur D. Quast