Patents Assigned to University
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Patent number: 10481162Abstract: The invention describes methods and reagents useful for sequencing polypeptide molecules. The method comprises affixing a polypeptide to a substrate and contacting the polypeptide with a plurality of probes. Each probe selectively binds to an N-terminal amino acid or an N-terminal amino acid derivative. Probes bound to the polypeptide molecule are then identified before cleaving the N-terminal amino acid or N-terminal amino acid derivative of the polypeptide. Also provided are methods for the sequencing a plurality of polypeptide molecules in a sample and probes specific for N-terminal amino acids or N-terminal amino acid derivatives.Type: GrantFiled: September 5, 2018Date of Patent: November 19, 2019Assignee: The Governing Council of the University of TorontoInventors: Andrew Emili, Megan McLaughlin, Kyrylo Zagorovsky, Jonathan Buchanan Olsen, Warren C. W. Chan, Sachdev S. Sidhu
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Patent number: 10481114Abstract: A core holder for a reservoir rock core sample for MR or MRI measurement including a casing and a chamber internal to the core holder, an inlet and an outlet in the core holder for circulating a confining fluid in the chamber, a sample housing in the chamber for containing the core sample, the sample housing including an inlet and an outlet in the sample holder for circulating fluid to and from the sample, and a membrane for isolating the sample from fluid contact with the confining fluid but permitting fluid pressure to be exerted on the sample when the confining fluid is pressurized, the space in the chamber not occupied by the sample housing defining a void space, an RF probe in the void space and at least partially surrounding the sample housing, whereby confining fluid introduced into the chamber circulates in the void space around the RF probe.Type: GrantFiled: August 11, 2017Date of Patent: November 19, 2019Assignee: University of New BrunswickInventors: Mojtaba Shakerian, Bruce J. Balcom
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Patent number: 10480922Abstract: A method of measuring a center error between bearings includes disposing both sides of a rotation shaft on inner circumferential surfaces of a magnetic bearing and a backup bearing, applying current to the magnetic bearing to produce movement of the rotation shaft, determining a contact point between the rotation shaft and the backup bearing according to movement of the rotation shaft, determining a final target value using the contact point and predetermined position information of the magnetic bearing, determining a magnetic center of the magnetic bearing through the final target value, comparing the magnetic center of the magnetic bearing and a mechanical center of the backup bearing to determine a center error, and aligning the magnetic center of the magnetic bearing and the mechanical center of the backup bearing based on the determined center error.Type: GrantFiled: June 6, 2017Date of Patent: November 19, 2019Assignees: LG Electronics Inc., The Industry & Academic Cooperation in Chungnam National UniversityInventors: Namsoo Lee, Myounggyu Noh, Soyoon Kim, Seongmin Jang, Jinhee Jeong, Seongki Baek, Sunggyu Nam
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Patent number: 10478489Abstract: The present invention relates to compositions and methods for the treatment and prevention of canine influenza virus (CIV) and CIV-related pathology. The present invention is based in part upon the discovery that various mutations in segment 1 and segment 2 of the CIV genome, thereby encoding mutant PB2 and PB1 protein, render the virus to be temperature-sensitive.Type: GrantFiled: August 19, 2016Date of Patent: November 19, 2019Assignees: University of Rochester, Cornell UniversityInventors: Luis Martinez-Sobrido, Aitor Nogales-Gonzalez, Colin Parrish
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Patent number: 10482210Abstract: A virtual force controlled collapse chip connection (C4) pad placement optimization frame-work for 2D power delivery grids is proposed. The present optimization framework regards power pads as mobile “positive charged particles” and current resources as a “negative charged back-ground.” The virtual electrostatic force is calculated from voltage gradients. This optimization framework optimizes pad locations by moving pads according to the virtual forces exerted on them by other pads and current sources in the system. Within this framework, three algorithms are proposed to meet various requirements of optimization quality and speed. These algorithms minimize resistive voltage drop (IR drop), the maximum current density, and power distribution network metal power dissipation at the same time.Type: GrantFiled: January 19, 2016Date of Patent: November 19, 2019Assignee: University of Virginia Patent FoundationInventors: Ke Wang, Kevin Skadron, Mircea R. Stan, Runjie Zhang, Brett Meyer
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Patent number: 10484881Abstract: A method, a computer readable medium and an apparatus for optimizing a cellular network architecture are disclosed. For example, the method obtains network traffic data for a plurality of different endpoint device types, wherein the network traffic data comprises network traffic data for each of the plurality of different endpoint device types, and predicts a future traffic pattern for one of the plurality of different endpoint device types based on the network traffic data. The method then adjusts a parameter of the cellular network architecture in response to the future traffic pattern predicted for the one of the plurality of different endpoint device types.Type: GrantFiled: June 26, 2017Date of Patent: November 19, 2019Assignees: AT&T Intellectual Property I, L.P., Board of Trustees of Michigan State UniversityInventors: Jia Wang, Lusheng Ji, Xiang-Yang Alexander Liu, Muhammad Zubair Shafiq
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Patent number: 10479854Abstract: A peptide-polymer conjugate is provided for use in treating malaria infections, and in particular terminal or drug resistant malaria infections. The conjugate is formed from a polymer to which a peptide having activity against a malaria parasite is co-valently attached. The peptide is a cyclic decapeptide from the closely-related group of tyrocidines, tryptocidines, phenycidines and gramicidin S, and the polymer is a hydrophilic and biocompatible polymer with a terminal thiol, such as poly(N-vinylpyrrolidone) (PVP). The polymer chains can be decorated with a hydrophilic targeting ligand that specifically targets an epitope on red blood cells, and in particular red blood cells infected with a plasmodial parasite. A method for synthesising the peptide-polymer conjugate is also provided.Type: GrantFiled: August 12, 2015Date of Patent: November 19, 2019Assignee: Stellenbosch UniversityInventors: Lubertus Klumperman, Paul William Reader, Marina Rautenbach
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Patent number: 10480403Abstract: A combustor having an ion transport membrane therein and an adjustable swirler, which is mechanically connected at an inlet of a combustion zone of the combustor; a combustion system comprising the combustor, a feedback control system adapted to adjust swirler blades of the combustor based on a compositional variation of a fuel stream, and a plurality of feedback control systems to control operational variables within the combustor for an efficient oxy-combustion; and a process for combusting a fuel stream via the combustion system. Various embodiments of the combustor, the combustion system, and the process for combusting the fuel stream are disclosed.Type: GrantFiled: November 30, 2016Date of Patent: November 19, 2019Assignee: King Fahd University of Petroleum and MineralsInventors: Esmail M. A. Mokheimer, Yinka S. Sanusi
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Patent number: 10479999Abstract: Described herein are bacterial microcompartments shell proteins modified to stably incorporate iron-sulfur clusters. Such bacterial microcompartments shell proteins exhibit redox cycling and confer electron transfer functionality to bacterial microcompartment shells.Type: GrantFiled: December 21, 2017Date of Patent: November 19, 2019Assignee: Board of Trustees of Michigan State UniversityInventors: Cheryl A. Kerfeld, Clement Aussignargues
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Patent number: 10479693Abstract: An electro-thermochemical cycling system for producing ammonia is provided that includes a reaction chamber having a metal compound input port, an anode suitable for oxidation in contact with the metal compound and configured for oxidation of hydroxide ions to water and oxygen, a cathode suitable for plating in contact with the metal compound and configured to electrolyze the metal compound to metal, a voltage source connecting the cathode and anode, a nitrogen port to the reaction chamber that combines nitrogen with the electrolyzed metal on the cathode to form a metal-nitrogen compound proximal to the nitrogen input, an atomic hydrogen port to the reaction chamber that combines with the metal-nitrogen compound to form ammonia, and an ammonia output port from the reaction chamber, where a metal compound input port inputs the metal compound to the reaction chamber according to a depletion rate of the metal compound in the reaction chamber.Type: GrantFiled: July 31, 2017Date of Patent: November 19, 2019Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Joshua M. McEnaney, John Schwalbe, Aayush Ranjan Singh, John Lin, Jakob Kibsgaard, Thomas F. Jaramillo, Matteo Cargnello, Jens K. Nørskov
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Patent number: 10483325Abstract: A photonic conversion device is provided, comprising a photoactive layer, a dielectric layer, a porous conductor layer, and an electron transport layer in contact with the porous conductor layer. A light emitting device may be in contact with the electron transport layer, forming a conversion device with gain. A method of manufacturing a photonic conversion device may also be provided, comprising forming a photoactive layer, forming a dielectric layer over the photoactive layer, and depositing a conductor layer in contact with the dielectric layer, wherein one or more regions of the dielectric layer are masked during deposition such that the conductor layer includes a plurality of pores that extend through the conductor layer.Type: GrantFiled: September 9, 2016Date of Patent: November 19, 2019Assignees: University of Florida Research Foundation, Incorporated, Nanoholdings, LLCInventors: Franky So, Do Young Kim, Hyeonggeun Yu, Bhabendra K. Pradhan
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Patent number: 10483645Abstract: A hybrid antenna array for use in an MRI device, the array comprising a plurality of loop-line elements, each loop line element comprising a loop element and a line element, wherein the loop element and the line element are aligned along their respective center axis and coupled at an input coil port; and wherein the plurality of loop-line elements are configured to operate in a multi-channel array.Type: GrantFiled: January 25, 2017Date of Patent: November 19, 2019Assignee: Regents of the University of MinnesotaInventors: Mehmet Arcan Erturk, Greg Metzger
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Patent number: 10480011Abstract: The disclosure in some aspects relates to recombinant adeno-associated viruses having distinct tissue targeting capabilities. In some aspects, the disclosure relates to gene transfer methods using the recombinant adeno-associated viruses. In some aspects, the disclosure relates to isolated AAV capsid proteins and isolated nucleic acids encoding the same.Type: GrantFiled: October 21, 2015Date of Patent: November 19, 2019Assignee: University of MassachusettsInventors: Guangping Gao, Jun Xie, Terence Flotte
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Patent number: 10481797Abstract: A data storage device may include: a memory cell array, a data buffer configured to generate a data chunk including a plurality of pages from input data provided from a host, a data compressor configured to compress the data chunk and output the compressed data chunk as write data, a write queue configured to store the write data on a page basis, a mapping table configured to store a mapping relationship between a logical address and a data chunk address, and a mapping relationship between the data chunk address and a physical address; and a controller configured to control an operation of storing the write data outputted from the write queue in the memory cell array such that a page including both a part of any one compressed data chunk and a part of another compressed data chunk is written to the memory cell array.Type: GrantFiled: January 19, 2017Date of Patent: November 19, 2019Assignees: SK hynix Inc., Seoul National University R&DB FoundationInventors: Sangwook Shane Hahn, Hoyoon Jun, Jihong Kim
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Patent number: 10480966Abstract: The present invention relates to an adaptable sensor assembly to be mounted to a light fixture in a fixture opening of the light fixture. A mount extends from the sensor housing. A break point is defined in the mount. First and second mount portions are located on either side of the break point. Each of the first and second mount portions are able to connect to the light fixture at the fixture opening. The first mount portion may connect to the light fixture if the light fixture has a large gasket lip, and the second portion may connect to the light fixture if the light fixture has a short gasket lip.Type: GrantFiled: February 2, 2017Date of Patent: November 19, 2019Assignee: Universal Lighting Technologies, Inc.Inventors: Rob Mahaffey, John Cavacuiti, Glen Tracey, Wilson Tse
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Patent number: 10478148Abstract: The present invention is directed to a method for enabling volumetric image reconstruction from unknown projection geometry of tomographic imaging systems, including CT, cone-beam CT (CBCT), and tomosynthesis systems. The invention enables image reconstruction in cases where it was not previously possible (e.g., custom-designed trajectories on robotic C-arms, or systems using uncalibrated geometries), and more broadly offers improved image quality (e.g., improved spatial resolution and reduced streak artifact) and robustness to patient motion (e.g., inherent compensation for rigid motion) in a manner that does not alter the patient setup or imaging workflow. The method provides a means for accurately estimating the complete geometric description of each projection acquired during a scan by simulating various poses of the x-ray source and detector to determine their unique, scan-specific positions relative to the patient, which is often unknown or inexactly known (e.g.Type: GrantFiled: February 17, 2017Date of Patent: November 19, 2019Assignee: The Johns Hopkins UniversityInventors: Jeffrey H. Siewerdsen, Yoshito Otake, Joseph Webster Stayman, Ali Uneri, Adam S. Wang, Sarah Ouadah
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Patent number: 10478805Abstract: Provided are a supported catalyst including: a support body which is formed by a catalyst composition being supported by a carrier, in which the catalyst composition contains an oxide of copper, and the carrier contains ?Al2O3.?B2O3 (? and ? each represent a positive number); and a hydrogen production method for producing hydrogen from ammonia, including: an ammonia combustion step of reacting ammonia with oxygen in the presence of the supported catalyst; and an ammonia decomposition step of decomposing the ammonia into hydrogen and nitrogen by utilizing heat generated by the reaction between the ammonia and the oxygen.Type: GrantFiled: August 4, 2016Date of Patent: November 19, 2019Assignee: National University Corporation Kumamoto UniversityInventors: Satoshi Hinokuma, Masato Machida
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Patent number: 10478101Abstract: A passive sensing continuous glucose monitoring system and method of use thereof. The system includes a passive antenna formed of biocompatible silicon carbide (SiC), modeled to a desired frequency, which is permanently implanted subcutaneously. The system further includes an external-to-the-body transmitting antenna to detect changes in the blood glucose level by sending a radio signal at the frequency of the implanted passive antenna into the body. This signal is received and reflected by the passive antenna, and the reflected signal is then received at an external-to-the-body receiving antenna. Changes in the glucose level lead to modifications in the signal and can be used to determine the blood glucose level externally.Type: GrantFiled: October 5, 2016Date of Patent: November 19, 2019Assignee: University of South FloridaInventors: Fabiola Araujo Cespedes, Stephen E. Saddow, Christopher Leroy Frewin, Erdem Topsakal
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Patent number: 10479696Abstract: Provided is a method for preparing molybdenum oxide nanoparticles, including (a) preparing a precursor solution by dissolving a molybdenum salt in a first polar solvent, (b) generating an aerosol by applying ultrasonic waves to the precursor solution, and spraying the aerosol to a pre-heated reactor using a carrier gas, (c) obtaining molybdenum oxide micron-sized particles by pyrolyzing the aerosol, and (d) obtaining molybdenum oxide nanoparticles by dispersing the molybdenum oxide micron-sized particles in a second polar solvent and performing a solvothermal reduction reaction.Type: GrantFiled: June 10, 2016Date of Patent: November 19, 2019Assignee: University-Industry Cooperation Group of Kyung Hee UniversityInventors: Jinsoo Kim, Sang Hyuk Im, Su Ha, Han-Seul Choi, Woo-Sik Kim, Sung Pil Yoon, Jonghee Han
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Patent number: 10478421Abstract: Provided herein are compounds and formulations thereof that can be capable of binding to sortilin or an analogue thereof. Also provided herein are methods of administering the compounds and formulation provided herein to a subject in need thereof.Type: GrantFiled: October 1, 2018Date of Patent: November 19, 2019Assignees: University of Florida, University of RochesterInventors: Robert Pleasants Sparks, Wayne Charles Guida, Janet Lindsay DeHoff-Sparks