Patents Assigned to University
  • Patent number: 11325963
    Abstract: The present invention includes methods and compositions for treating cancer, whether a solid tumor or a hematologic malignancy. By expressing a chimeric antigen receptor in a monocyte, macrophage or dendritic cell, the modified cell is recruited to the tumor microenvironment where it acts as a potent immune effector by infiltrating the tumor and killing the target cells. One aspect includes a modified cell and pharmaceutical compositions comprising the modified cell for adoptive cell therapy and treating a disease or condition associated with immunosuppression.
    Type: Grant
    Filed: September 16, 2021
    Date of Patent: May 10, 2022
    Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Saar Gill, Michael Klichinsky, Carl H. June
  • Patent number: 11328394
    Abstract: Provided is a deep learning based contrast-enhanced (CE) CT image contrast amplifying method and the deep learning based CE CT image contrast amplifying method includes extracting at least one component CT image between a CE component and a non-CE component for an input CE CT image with the input CE CT image as an input to a previously trained deep learning model; and outputting a contrast-amplified CT image with respect to the CE CT image based on the input CE CT image and the at least one extracted component CT image.
    Type: Grant
    Filed: July 20, 2021
    Date of Patent: May 10, 2022
    Assignees: CLARIPI INC., SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
    Inventors: Jong Hyo Kim, Hyun Sook Park, Tai Chul Park, Chul Kyun Ahn
  • Patent number: 11326398
    Abstract: The present disclosure provides a portable seafloor drill rig for a submersible for multi-point core drilling, including a power head, a reduction gear box, an emergency jettison device, a drilling tool, and a temperature and pressure-retaining device. a water supply connector and the power head are arrange on a top plate of the reduction gear box. An output shaft of the power head is connected to an input shaft of the reduction gear box, and an output shaft of the reduction gear box is provided with a central hole, which is in communication with a water inlet hole of the water supply connector. An output shaft of the reduction gear box is connected to the emergency jettison device, and the temperature and pressure-retaining device can perform temperature and pressure-retaining storage of the core drilled by the drilling tool.
    Type: Grant
    Filed: January 20, 2021
    Date of Patent: May 10, 2022
    Assignee: HUNAN UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Yongping Jin, Liang Liu, Youduo Peng, Buyan Wan, Jun Gong, Jian Yan
  • Patent number: 11325073
    Abstract: Disclosed herein are spacers having baffle designs and perforations for efficiently and effectively separating one or more membrane layers a membrane filtration system. The spacer includes a body formed at least in part by baffles that are interconnected, and the baffles define boundaries of openings or apertures through a thickness direction of the body of the spacer. Alternatively or additionally, passages or perforations may be present in the spacer layer or baffles for fluid flow there through, with the passages and baffles having a numerous different shapes and sizes.
    Type: Grant
    Filed: April 4, 2017
    Date of Patent: May 10, 2022
    Assignee: KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Noreddine Ghaffour, Adnan Qamar
  • Patent number: 11325112
    Abstract: Nanocages are formed by etching nanocubes. The nanocubes are added to an aqueous system having an amphiphilic lipid dissolved in an organic solvent (e.g. a hydrophobic alcohol) to form reverse micelles. As the water evaporates the micelles shrink as etching of the flat surface of the nanocubes occurs. In this fashion hollow nanocages are produced. In one embodiment, the nanocage is covalently attached to a polymer shell (e.g. a dextran shell).
    Type: Grant
    Filed: May 18, 2020
    Date of Patent: May 10, 2022
    Assignee: Research Foundation of the City University of New York
    Inventors: Hiroshi Matsui, Zengyan Wei, Justin Fang
  • Patent number: 11329582
    Abstract: The present invention provides a series shunt wound direct-current (DC) motor driving device and electrical equipment. The series shunt wound DC motor driving device provided by the present invention includes a series shunt wound DC motor, a DC power supply and a chopper.
    Type: Grant
    Filed: December 27, 2019
    Date of Patent: May 10, 2022
    Assignee: UNIVERSITY OF SHANGHAI FOR SCIENCE AND TECHNOLOGY
    Inventors: Shaolong Li, Aijuan Jin
  • Patent number: 11328125
    Abstract: According to an aspect of an embodiment, a method for a text classification using multi-task learning executed by a server, the method includes: a step of generating text classification learning data by executing a pre-processing process on raw data collected through a network; a step of learning a category classification in a first classification system preset through a first text classification model using the text classification learning data as an input; a step of learning a category classification in a second classification system preset through a second text classification model using the text classification learning data as an input; and a step of classifying the category in the second classification system by inputting text data received from a user terminal into the second text classification model.
    Type: Grant
    Filed: May 13, 2020
    Date of Patent: May 10, 2022
    Assignee: Korea University Research and Business Foundation
    Inventors: Sang Keun Lee, Kang-Min Kim, Jungho Lee
  • Patent number: 11324430
    Abstract: Example apparatuses, systems, and methods for detecting a muscle tissue ischemia event are provided. An example apparatus may include an electromyography (EMG) sensor applied to a patient to detect electrical activity in the muscle tissue. The apparatus may also include processing circuitry in communication with the EMG sensor and configured to receive EMG signals from the EMG sensor and detect characteristics within the EMG signals indicating oxygen depletion within the muscle tissue of the patient. The characteristics may include a signal power level of the EMG signals increasing by at least a threshold value at a select frequency or with respect to a select band of frequencies. The processing circuitry may be further configured to trigger an output, in response to detecting the characteristics, indicating that the oxygen depletion in the muscle tissue is indicative of an ischemia event.
    Type: Grant
    Filed: November 14, 2018
    Date of Patent: May 10, 2022
    Assignee: The Johns Hopkins University
    Inventor: Wayne I. Sternberger
  • Patent number: 11329809
    Abstract: This invention relates generally to a method and system for hybrid classical-quantum communication. The method comprises transmitting a single photon having a particular quantum state over a communication medium using a quantum mode set; and transmitting a classical light beam over the same communication medium using a classical mode set, wherein the classical and quantum mode sets comprise non-separable modes in common. The non-separable modes in common may be two degrees of freedom of a single photon or classical light and may thus be spatial modes in one or more indexes, and polarisation. The invention relates also to a system to implement the method accordingly.
    Type: Grant
    Filed: January 23, 2018
    Date of Patent: May 10, 2022
    Assignee: UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG
    Inventors: Andrew Forbes, Bienvenu Ndagano, Isaac Nape, Mitchell Cox, Carmelo Rosales-Guzman
  • Patent number: 11328434
    Abstract: An object tracking device includes a superimposed image creation unit configured to create a plurality of superimposed images in which each of a plurality of non-tracking object images which do not include a tracking object image feature is superimposed on a tracking object section image which includes a tracking object image feature; a discriminator creation unit configured to learn at least one of an image feature and position information of the tracking object, based on the plurality of superimposed images to create a discriminator; and a tracking object specifying unit configured to specify at least one of the image feature and the position information of the tracking object in a tracked image including the respective image features of the tracking object and an obstacle, based on the discriminator and the tracked image.
    Type: Grant
    Filed: March 1, 2018
    Date of Patent: May 10, 2022
    Assignee: UNIVERSITY OF TSUKUBA
    Inventors: Toshiyuki Terunuma, Takeji Sakae
  • Patent number: 11324704
    Abstract: Provided is a sustained release sheet that includes a drug for treating nerve injury, wherein the sheet is applied to a nerve injury site, can maintain a high concentration of the drug over a long period, and promotes nerve regeneration without stimulating the nerves, even when the sheet is implanted in the periphery of the nerve injury site. Also provided is a production method for the sheet. This sustained drug release sheet for treating nerve injury is a sheet comprising a non-woven fabric that is formed from nanofibers each containing a drug such as vitamin B12 and a biocompatible polymer such as a biodegradable aliphatic polyester, and is implanted in the periphery of the nerve injury site to promote nerve regeneration.
    Type: Grant
    Filed: March 6, 2017
    Date of Patent: May 10, 2022
    Assignees: OSAKA UNIVERSITY, NATIONAL INSTITUTE FOR MATERIALS SCIENCE, NIPPON ZOKI PHARMACEUTICAL CO., LTD.
    Inventors: Hiroyuki Tanaka, Kiyoshi Okada, Hideki Yoshikawa, Koji Suzuki, Mitsuhiro Ebara
  • Patent number: 11327326
    Abstract: The present disclosure discloses a real-time micro/nano optical field generation and manipulation system and method. The system comprises a light source, a spatial filtering unit, an optical 4F system and a light wave manipulation unit, and the optical 4F system comprises a first lens (set) and a second lens (set) sequentially arranged along a light path. The present disclosure achieves real-time modulation on an incident wavefront through a phase element or a phase element assemble. By dynamically manipulating an incident light sub-wavefront, or the light wave modulation optical element, or different areas of the optical element, or different parts of the optical field in an imaging plane and/or the like by the spatial filtering unit, real time light fields with different parameters are generated in the image plane of the system.
    Type: Grant
    Filed: November 27, 2017
    Date of Patent: May 10, 2022
    Assignee: Soochow University
    Inventors: Yan Ye, Yishen Xu, Linsen Chen
  • Patent number: 11324837
    Abstract: Disclosed herein are embodiments of nanoparticle composites that comprise covalently coupled stabilizing agent molecules that improve stability of the nanoparticle composites and allow for tight packing of lipids and/or membranes. The nanoparticle composites can further comprise inhibition inhibitors and/or lipid components that interact to form a hybrid lipid bilayer membrane around the nanoparticle core. The nanoparticle composites can be coupled to drugs, targeting moieties, and imaging moieties. The nanoparticle composites can be used for in vivo drug deliver, disease diagnosis/treatment, and imaging.
    Type: Grant
    Filed: September 10, 2018
    Date of Patent: May 10, 2022
    Assignee: Portland State University
    Inventor: Marilyn Mackiewicz
  • Patent number: 11324835
    Abstract: A unit-type polyion complex for use in delivering nucleic acid to a target site in a patient includes one or more molecules of a block copolymer having a poly(ethylene glycol) segment and a cationic poly(amino acid) segment and one or more molecules of a nucleic acid. A total quantity of positive charges derived from side chains of the cationic poly(amino acid) segment of the block copolymer in the unit-type polyion complex is not offset by a total quantity of negative charges derived from the nucleic acid. Furthermore, the nucleic acid has a strand length of 10-50 bases, the molecular weight of the poly(ethylene glycol) segment is 40×103 or more, and the block copolymer has a binding constant (Ka) for the nucleic acid of 3.0×105 or more.
    Type: Grant
    Filed: August 30, 2018
    Date of Patent: May 10, 2022
    Assignees: KAWASAKI INSTITUTE OF INDUSTRIAL PROMOTION, THE UNIVERSITY OF TOKYO
    Inventors: Kazunori Kataoka, Kanjiro Miyata, Shigeto Fukushima, Kotaro Hayashi, Sumiyo Watanabe, HyunJin Kim, Kazuko Toh
  • Patent number: 11324403
    Abstract: A new born temperature and heart monitor wrap apparatus and method includes a wrap where the wrap is configured such that a new born is substantially covered by the wrap when the wrap is applied to the new born. A heart monitor device is attached to the wrap and a temperature lead retainer is attached to the wrap. A substrate is provided where the wrap is removably connected to the substrate.
    Type: Grant
    Filed: October 12, 2017
    Date of Patent: May 10, 2022
    Assignee: University of South Alabama
    Inventors: Fabien Gabriel Eyal, Om Prakash Jha
  • Patent number: 11330697
    Abstract: A laser-produced plasma X-ray system includes a liquid metal flow system enclosed within a low-pressure chamber, the flow system including a liquid metal, wherein in at least one location on the liquid metal forms a metal target beam, a circulation pump within the flow system for circulating the liquid metal, a laser pulse emitter configured to transmit a plurality of laser pulses into the chamber via a laser window, focusing optics, located between the emitter and the metal target beam, the focusing optics directing the laser pulses to strike the metal target beam at a target location to form X-ray pulses, and an X-ray window positioned within the chamber to allow the X-ray pulses to exit the chamber.
    Type: Grant
    Filed: December 27, 2017
    Date of Patent: May 10, 2022
    Assignees: Brown University, Research Instruments Corporation
    Inventor: Christoph Rose-Petruck
  • Patent number: 11326178
    Abstract: The invention relates to nucleic acids encoding a p-coumaroyl-CoA:monolignol transferase and to inhibitory nucleic acids adapted to inhibit the expression and/or translation of a p-coumaroyl-CoA:monolignol transferase RNA. Inhibition of p-coumaroyl-CoA:monolignol transferase in plants improves the incorporation of monolignol ferulates into the lignin of plants, giving rise to plant biomass that is more easily processed into useful products such as paper and biofuels.
    Type: Grant
    Filed: August 14, 2019
    Date of Patent: May 10, 2022
    Assignees: Wisconsin Alumni Research Foundation, Board of Trustees of Michigan State University, The Board of Trustees of Illinois State University
    Inventors: Curtis Wilkerson, John Ralph, Saunia Withers, John Sedbrook
  • Patent number: 11329389
    Abstract: A method for fabricating a hyperbolic metamaterial coating having a near-zero refractive index is disclosed. The direction of propagating light changes by means of generating subwavelength structures that alter the coatings permittivity and permeability. The coating can be deposited on lenses or incorporated into optical devices. This type of metamaterial can be utilized to direct light towards sensors or to collect light efficiently.
    Type: Grant
    Filed: July 24, 2019
    Date of Patent: May 10, 2022
    Assignee: Board Of Regents, The University of Texas System
    Inventors: Nantakan Wongkasem, Andres Ochoa
  • Patent number: 11325839
    Abstract: A method of using ZnO particles for the treatment of colon cancer and a method of using the particles for reducing the concentration of an organic contaminant in an aqueous solution is described. The ZnO particles are substantially spherical and may have nanopetals that provide a nanoflower morphology. The synthesis and characterization of the ZnO particles is also discussed.
    Type: Grant
    Filed: January 11, 2018
    Date of Patent: May 10, 2022
    Assignee: Imam Abdulrahman Bin Faisal University
    Inventors: Faiza Qureshi, Muhammad Nawaz
  • Patent number: 11326400
    Abstract: Disclosed is a drillable adaptive turbine guide shoe, including an adaptive booster component and a power casing shoe component; the adaptive booster component includes a supercharging hollow shaft, a supercharging shell, a disc spring group, a shunt head, a jet oscillator and a semi-cylindrical ring, the supercharging hollow shaft is slidably connected to the supercharging shell, one end of the supercharging hollow shaft is a liquid inlet end and the other end is closed, a cavity is formed between the supercharging hollow shaft and the supercharging shell, and the disc spring group is built in the cavity, the jet oscillator and the semi-cylindrical ring are mounted on the inner wall of the supercharging shell, and one side of the jet oscillator and the semi-cylindrical ring abuts against the shunt head, the shunt head is sleeved on the outer wall of the supercharging hollow shaft; this disclosure solves the problem that the casing cannot be effectively run when the wellbore has sand bridges or wellbore necki
    Type: Grant
    Filed: March 25, 2021
    Date of Patent: May 10, 2022
    Assignee: YANGTZE UNIVERSITY
    Inventors: Ding Feng, Yu Zhao