Abstract: Provided herein are methods and devices for accurate sequencing and detection of epigenetic information from template polynucleotides. Also provided are methods for long-range strand displacement amplification of polynucleotides, microfluidic devices with selectively permeable barriers for multistep processing, and methods for polynucleotide amplification using the microfluidic devices.

Abstract: Methods and apparatus for deep microscopic super resolution imaging use two independent and variable focal planes. Movements of fiducial markers imaged using one focal plane are monitored and used to provide real-time or near real-time correction for sample drift. A second focal plane may be used to collect light for super-resolution imaging of a sample. A prototype embodiment has produced low drift when imaging many microns deeper than the fiducial markers.

Abstract: The disclosure relates to a method for detecting surface electric field distribution of nanostructures. The method includes the following steps of: providing a sample located on an insulated surface of a substrate; spraying first charged nanoparticles to the insulated surface; and blowing vapor to the insulated surface to observe a distribution of the first charged nanoparticles via an optical microscope.

Abstract: Disclosed is a method and apparatus for IP-based hybrid 3DTV content transmission and reception. According to one aspect of the present disclosure, an IP-based hybrid 3DTV content reception apparatus includes: a receiving unit receiving multiplexed 3DTV content information; an additional data obtaining unit obtaining service layer signaling information from the received 3DTV content information, and obtaining additional data based on the obtained service layer signaling information; a decoding unit decoding the received 3DTV content information by using the obtained additional data; and a playing back unit playing back the decoded 3DTV content.

Abstract: Provided herein are methods and compositions for enhancing an immune response and/or for the treatment of an immune-related condition in an individual, e.g., cancer, comprising killing, disabling, or depleting non-stimulatory myeloid cells using an antigen binding protein such as an antibody or antigen binding fragment thereof.

Abstract: The present invention relates generally to the detection or diagnosis of post-traumatic stress states in a subject, and provides methods, reagents, and kits useful for this purpose. Provided herein are biomarkers that are indicative of and/or diagnostic of post-traumatic stress states including PTSD.

Abstract: System and method directed towards providing full and even illumination of a patient's retina through lighting integrated into a handheld fundus lens. By integrating the lighting, the method and system reduces and even eliminate many lens artifacts and reflections. By increasing the accuracy, quality, and field of view afforded during clinical examination of the retina, the method and system will allow practitioners to make more accurate diagnoses and will increase safety during retinal surgical procedures.

Abstract: A stacked composite material and a method of preparation, wherein the stacked composite materials comprises of glass fiber layers sandwiched between nanocomposite layers. The nanocomposite layers comprise a nanofiller dispersed in a cured epoxy matrix, wherein the nanofiller is at least one of silicon carbide nanoparticles or aluminum oxide nanoparticles. Adjacent and noncontiguous glass fiber layers are oriented in a unidirectional orientation or a quasi-isotropic orientation.

Abstract: The disclosure relates to a thin film transistor and a method for making the same. The thin film transistor includes a substrate; a semiconductor layer on the substrate, wherein the semiconductor layer includes nano-scaled semiconductor materials; a source and a drain, wherein the source and the drain are on the substrate, spaced apart from each other, and electrically connected to the semiconductor layer; a dielectric layer on the semiconductor layer, wherein the dielectric layer includes a first sub-dielectric layer and a second sub-dielectric layer stacked on one another, and the first sub-dielectric layer is a first oxide dielectric layer grown by magnetron sputtering; and a gate in direct contact with the first sub-dielectric layer. The thin film transistor almost has no current hysteresis.

Abstract: A catalyst particle is composed of an inner particle and an outermost layer that includes platinum and covers the inner particle. The inner particle includes on at least a surface thereof a first oxide having an oxygen defect.

Abstract: Nanoscale stress-sensing can be used across fields ranging from detection of incipient cracks in structural mechanics to monitoring forces in biological tissues. We demonstrate how tetrapod quantum dots (tQDs) embedded in block-copolymers act as sensors of tensile/compressive stress. Remarkably, tQDs can detect their own composite dispersion and mechanical properties, with a switch in optomechanical response when tQDs are in direct contact. Using experimental characterizations, atomistic simulations and finite-element analyses, we show that under tensile stress, densely-packed tQDs exhibit a photoluminescence peak shifted to higher energies (“blue-shift”) due to volumetric compressive stress in their core; loosely-packed tQDs exhibit a peak shifted to lower energies (“red-shift”) from tensile stress in the core. The stress-shifts result from the tQD's unique branched morphology in which the CdS arms act as antennas that amplify the stress in the CdSe core.

Abstract: An oceaneering test platform device for simulating oceaneering working conditions is disclosed. The oceaneering test platform device comprises a main body, a lifting unit, a plurality of spud legs connected to the main body by the lifting unit, a plurality of base units located correspondingly to the plurality of spud legs and one or more vertical driving unit to enable vertical movement of at least one of the plurality of spud legs. The test platform device facilitates simulation of possible effects caused by unstable and complex ocean environments to an offshore work platform.

Abstract: A method for detecting and quantifying haloether contamination in aqueous samples. A flow state is artificially induced upon an aqueous sample and a solid phase microextraction (SPME) fiber, upon which an electric potential is applied, is exposed to the flowing aqueous sample in direct immersion mode. Halide ions liberated from electrophoretically dehalogenated haloether compounds contained in the aqueous sample are absorbed upon the SPME fiber, then later desorbed at a gas chromatograph, separated into individual halide ions and analyzed by mass spectrometry. Effects of various parameters such as absorption time, sample pH, salt content, applied voltage, SPME fiber type, flow rate and background matrix are also described.

Abstract: A visual image processing method is based on received spatial field information (302) from a spatial field sensor (116). A data store (804) is accessed, which contains a sensor map data structure (206) comprising a set of predefined regions (208) within a spatial field corresponding with the information received via the sensor input. Each predefined region is associated in the data structure with one or more of a set of stimuli (204) applicable to a biological visual system, and each stimulus corresponds with a visual percept (210). The spatial field information associated with each region is processed to generate stimulus control information which is applied to select, from within the sensor map data structure, stimuli from the set of stimuli for application to the biological visual system. Output stimulus signals (310) are generated, which are suitable for application to the biological visual system based upon the selected stimuli.

Abstract: Systems and methods are provided for imaging using complex lasers. In general, a complex laser may be used as an electromagnetic source for an imaging application. The use of a lower spatial coherence configured complex laser in imaging applications may advantageously mitigate coherent artifacts in imaging such as cross-talk and speckle and improve overall image quality. Imaging applications where a complex laser may be useful include both incoherent imaging applications, such as digital light projectors and traditional microscopy, and coherent imaging applications, such as optical coherence tomography (OCT) and holography. The systems and methods provided also enable controlling the degree of spatial coherence of a complex laser.

Abstract: A modular system for containing electronic components has at least one storage bin and a plurality of Radio Frequency Interference (RFI) shielded electronics enclosures. Each RFI shielded electronics enclosure is at least one hollowed-out body; at least one hollowed-out cover, wherein the at least one hollowed-out cover is adapted to mate with the at least one hollowed-out body; and a plurality of fastening devices adapted to secure the at least one hollowed-out cover to the at least one hollowed-out body.

Abstract: Disclosed herein are porous asymmetric silicon membranes. The membranes are characterized by high structural stability, and as such are useful as anode components in lithium ion batteries.

Abstract: Provided is a speech enhancement method and a system therefor. The speech enhancement method includes receiving at least one speech signal; generating a first speech signal by performing a primary speech enhancement on the at least one speech signal; selecting a noise removing gain corresponding to the first speech signal from pre-learned noise removing gain information; and generating a second speech signal by performing a secondary speech enhancement on the first speech signal based on the selected noise removing gain.

Abstract: Isolated polynucleotides comprising an OLIG1 mini-promoters are provided. The mini-promoter may be operably linked to an expressible sequence, e.g. reporter genes, genes encoding a polypeptide of interest, guide RNA, regulatory RNA sequences such as miRNA, siRNA, anti-sense RNA, etc., and the like. The promoter may also be provided in a vector, for example in combination with an expressible sequence. The polynucleotides find use in a method of expressing a sequence of interest, e.g. for identifying or labeling cells, monitoring or tracking the expression of cells, gene therapy, etc.

Abstract: The present invention relates to a compound represented by the general formula (A), a base generator comprising the compound, a base-reactive composition which comprises the base generator and a base-reactive compound, as well as a method for generating a base, etc.