Abstract: A method and system for predicting an addition amount of slagging lime during ladle furnace (LF) refining, and an LF refining method are provided. The method includes: S1: calculating an actual sulfur distribution ratio in combination with a Kungliga Tekniska Högskolan (KTH) model and a least square method by using LF refining parameters; S2: calculating, according to a principle of sulfur mass conservation, a mass of final slag by using the LF refining parameters and the actual sulfur distribution ratio obtained in S1; and S3: calculating, according to a principle of material conservation during LF refining, an addition amount of slagging lime during the LF refining by using the LF refining parameters and the mass of the final slag obtained in S2, thereby predicting the addition amount of the required slagging lime.
Type:
Application
Filed:
September 18, 2021
Publication date:
May 12, 2022
Applicant:
University of Science and Technology Beijing
Abstract: A test apparatus is disclosed that has a housing containing a location at which a sample tray containing a plurality of sample wells can be located, a light box positioned to permit irradiation of the sample tray, and an imaging arrangement to permit imaging of the sample tray. The light box has a light source including a light guide in the form of a plate of a transparent material and a plurality of light emitting devices provided adjacent at least one edge of the plate where a surface of the plate is provided with a plurality of transmitting regions and light is transmitted from the plate.
Type:
Application
Filed:
February 12, 2020
Publication date:
May 12, 2022
Applicant:
UNIVERSITY OF EXETER
Inventors:
Robert BEARDMORE, Ivana BEARDMORE, Kai LONGSHAW, Carlos REDING
Abstract: An object of the present invention is to provide an antifungal agent which is effective against cryptococcosis. The present invention provides an antifungal agent comprising ravuconazole as an active ingredient, wherein the agent is administered to an animal suffering from cryptococcosis. Further, the present invention provides an antifungal agent comprising ravuconazole as an active ingredient, wherein the agent is administered to an animal suffering from cryptococcus that is resistant to triazole-based antifungal agents selected from the group consisting of fluconazole, itraconazole and voriconazole.
Type:
Application
Filed:
April 6, 2020
Publication date:
May 12, 2022
Applicants:
SEREN PHARMACEUTICALS INC., NIHON UNIVERSITY
Abstract: The present invention provides acoustically activated liposome compositions for use as drug delivery vehicles, and to methods for drug release and drug delivery for therapeutic applications including Parkinson's disease and epilepsy.
Type:
Application
Filed:
January 20, 2022
Publication date:
May 12, 2022
Applicant:
UNIVERSITY OF OTAGO
Inventors:
John Noble James REYNOLDS, Eng Wui TAN, Brian Ian HYLAND, Guy Nicholas Louis JAMESON, Maung Mo Aung MYINT, Sean Marshall MACKAY, Jeffery Russell WICKENS
Abstract: An impedance matching method for a low-profile ultra-wideband array antenna is provided. The method includes: connecting an arm of a balanced end of a hyperbolic microstrip balun in series with an open circuit line; directly coupling the open circuit line to a radiator layer; connecting another arm of the balanced end of the hyperbolic microstrip balun to the radiator layer via a metallized via hole, and welding an unbalanced end of the hyperbolic microstrip balun to a coaxial line, so that the coaxial line feeds a power to the antenna via the hyperbolic microstrip balun. In this method, the open circuit line is integrated between the hyperbolic microstrip balun and the radiator layer of the antenna to achieve an impedance matching of the ultra-wideband antenna and to simplify a structure of a matching circuit.
Type:
Application
Filed:
July 21, 2021
Publication date:
May 12, 2022
Applicant:
Hangzhou Dianzi University
Inventors:
Zhiqun CHENG, Peng GAO, Ruoyu HE, Zhen WANG
Abstract: It is aimed to provide a power supply device and a power supply system which enable consumers to freely choose electrical power and specify transmission sources when receiving electrical power, and enable parties involved in transactions (power supply side and power receiving side) to reliably and safely perform transmission between them. There are provided a power supply device and a power supply system. The power supply device includes a baseband unit that generates a power signal, a modulation processing unit that modulates the power signal generated by the baseband unit to impart a code thereto for specifying a transmission source of the power signal and generates a modulated signal that can be demodulated by a power receiving device, and a transmission unit that transmits the modulated signal generated by the modulation processing unit.
Type:
Application
Filed:
March 13, 2020
Publication date:
May 12, 2022
Applicants:
KYOTO UNIVERSITY, MINNA-DENRYOKU, INC.
Inventors:
Ken UMENO, Eiji OISHI, Yoshitaka NISHIMURA
Abstract: Disclosed are an encryption and decryption method and device based on bit permutation and bit transformation. The method includes: configuring a memory space, and preparing corresponding storage spaces for a plaintext file, a ciphertext file and a key file; changing a bit value of an initial key stream according to a bit operation rule, so as to obtain a bit-transformed key stream, changing a bit value of a plaintext according to the bit operation rule depending on the key stream; on the basis of a bit-transformed plaintext stream, according to a bit permutation rule depending on the key stream, performing a bit permutation operation on the bit-transformed plaintext stream, and randomly distributing the plaintext stream in a ciphertext stream, so as to obtain a target ciphertext and store the same as a file.
Type:
Application
Filed:
April 19, 2019
Publication date:
May 12, 2022
Applicants:
Zhuhai College of Science And Technology, Jilin University
Abstract: The present disclosure provides modified microRNA nucleic acid compositions that have one or more cytosine and/or uracil bases replaced with gemcitabine or a 5-halouracil, respectively. More specifically, the present disclosure reveals that the replacement of cytosine nucleotides within a microRNA nucleotide sequence with a gemcitabine molecule increases the ability of the microRNA to inhibit cancer progression and tumorigenesis. In addition, the present disclosure reveals that the replacement of cytosine nucleotides within a microRNA nucleotide sequence with a gemcitabine molecule and replacement of uracil bases with 5-halouracil increases the ability of the microRNA to inhibit cancer development. As such, the present disclosure provides various modified nucleic acid (e.g., microRNA) compositions having gemcitabine molecules incorporated in their nucleic acid sequences and methods for using the same.
Type:
Application
Filed:
March 13, 2020
Publication date:
May 12, 2022
Applicant:
The Research Foundation for The State University of New York
Abstract: A method for predicting a remaining life of a tool of a computer numerical control machine is provided. In the method, indirect measurement indicators of the tool are selected based on monitoring and analyzing a current state of the tool, a prediction model for the remaining life of the tool is established based on data de-noising, feature extraction and a multi-kernel W-LSSVM algorithm. Thereby, a method for predicting a remaining life of a tool of a computer numerical control machine is provided.
Type:
Application
Filed:
May 15, 2020
Publication date:
May 12, 2022
Applicant:
CHONGQING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS
Abstract: The present disclosure relates to a system and method for updating traffic-related infrastructure. The method includes determining average traffic stream speed and average traffic density over a segment of a highway. The method further includes determining, upon analysis of the determined average traffic stream speed and average traffic density over a segment of a highway, an appropriate action in order to update the infrastructure.
Abstract: To provide a method for analyzing coagulation characteristics of a blood specimen. To provide a method for analyzing a blood specimen, including: acquiring a waveform related to a coagulation rate or coagulation acceleration of a sample obtained by mixing a subject blood specimen with a reagent for measuring coagulation time; extracting multiple parameters characterizing the waveform related to a coagulation rate or a coagulation acceleration; and determining an activity level or activity abnormality of a coagulation factor in the subject blood specimen on the basis of the multiple parameters.
Type:
Application
Filed:
January 31, 2020
Publication date:
May 12, 2022
Applicants:
SEKISUI MEDICAL CO., LTD., PUBLIC UNIVERSITY CORPORATION NARA MEDICAL UNIVERSITY
Abstract: According to the present invention, there is provided a method of decoding a video signal, the method including: determining an intra prediction mode of a current block; applying a filter to a first reference sample adjacent to the current block; obtaining a first prediction sample of the current block on the basis of the intra prediction mode and a second reference sample obtained by applying the filter; and obtaining a second prediction sample of the current block using the first prediction sample and the first reference sample.
Type:
Application
Filed:
January 24, 2022
Publication date:
May 12, 2022
Applicant:
Industry Academy Cooperation Foundation of Sejong University
Inventors:
Yung-Lyul LEE, Nam Uk KIM, Jun Woo CHOI
Abstract: Methods and compositions for treatment of malignancies are provided. The methods utilize implantation of engineered, programmable hydrogel depots capable of long-term molecule release into close proximity of the tumor. By providing gradients of immune cell chemokines and releasing immune checkpoint inhibitors, the hydrogel implants are effective at elimination of tumor cells via immune cell-mediated cell death.
Type:
Application
Filed:
February 27, 2020
Publication date:
May 12, 2022
Applicants:
Fred Hutchinson Cancer Research Center, University of Washington
Inventors:
James Olson, Eric Nealy, Cole DeForest, Kenneth Brasel
Abstract: Provided is a catalyst for amide compound hydrogenation characterized in that rhodium and molybdenum are supported on hydroxyapatite, the catalyst for amide compound hydrogenation providing a catalyst that can promote a reduction reaction that converts an amide compound into an amine compound, can be used under moderate conditions, and has durability that allows repeated use thereof while retaining high activity. Also provided is a method for producing an amine compound, the method being characterized by including bringing an amide compound into contact with the catalyst for amide compound hydrogenation to cause hydrogenation, thereby producing an amine compound.
Abstract: This invention provides for a flow synthesis process for producing Oseltamivir and pharmaceutically acceptable salts thereof from shikimic acid in particular but not exclusively to a flow synthesis process for producing Oseltamivir phosphate from shikimic acid in a nine-step flow synthesis that provides for superior reaction times and product yields compared to known methods.
Abstract: Provided is a platinum complex having a structure represented by formula (I): wherein A1 to A3 each independently represent a 5-membered or 6-membered unsaturated ring, A3 is optionally formed between A1 and A2; X1, X2, and X3 each independently represent carbon or nitrogen; R1 represents hydrogen, substituted or unsubstituted C1-C6 alkyl, —CF2H, —CFH2, substituted or unsubstituted C6-C12 aryl or —CmF2m+1, m is an integer of 1 to 5; R2 and R3 each independently represent hydrogen, C1-C12 alkyl, substituted or unsubstituted C1-C6 alkoxyl, substituted or unsubstituted C6-C12 aryl, or —CnF2n+1, n is an integer of 0 to 3; p and q each independently represent an integer of 1 to 2; and when p or q is equal to 2, two R2's or R3's may join to form a C3-C8 aromatic or nitrogen-containing heteroaromatic ring.
Type:
Application
Filed:
January 14, 2021
Publication date:
May 12, 2022
Applicants:
National Tsing Hua University, City University of Hong Kong
Abstract: Described herein are isolated peptides, compositions comprising the same, and methods of using such peptides or compositions in the treatment of depression, central nervous system disorders, and neurodevelopmental disorders.
Abstract: The present invention relates to compositions for uses including mineralizing a dental surface, in particular tooth enamel. Methods of mineralizing hypomineralized lesions (including subsurface lesions) in the tooth enamel caused by various means including dental caries, dental corrosion and fluorosis are also provided. In one aspect, the present invention provides a method of mineralizing a dental surface or sub-surface comprising contacting the dental surface or subsurface with stabilized amorphous calcium phosphate (ACP) and/or amorphous calcium fluoride phosphate (ACFP), and simultaneously or subsequently, heating the dental surface or subsurface to which the stabilized ACP and/or ACFP has been, or is being, applied to a temperature greater than 37° C.
Abstract: Provided herein are methods of using ClpP levels and mutation status as a marker for the selection and treatment of cancer patients who will respond to the administration of imipridones. Also provided are methods of treating patients having Perrault syndrome. Also provided are methods of killing bacterial cells and treating bacterial infections using imipridones.
Type:
Application
Filed:
February 21, 2020
Publication date:
May 12, 2022
Applicants:
Board of Regents, The University of Texas System, University Health Network
Inventors:
Michael ANDREEFF, Jo ISHIZAWA, David SCHIMMER, Sara ZARABI