Patents Assigned to University
  • Mining All Atom Simulations for Diagnosing and Treating Disease
    Publication number: 20190189243
    Abstract: The present disclosure describes methods for determining the functional consequences of mutations. The methods include the use of machine learning to identify and quantify features of all atom molecular dynamics simulations to obtain the disruptive severity of genetic variants on molecular function.
    Type: Application
    Filed: December 19, 2018
    Publication date: June 20, 2019
    Applicant: George Mason University
    Inventors: Mohsin Saleet Jafri, Matthew McCoy
  • Annealing Process
    Publication number: 20190185979
    Abstract: An annealing process for treatment of an aluminum alloy of AA5XXX series which comprises steps of annealing the aluminum alloy at a first temperature of from about 350° C. to about 450° C. by a rate of temperature increase from about 0.1° C./s to about 0.5° C./s; and cooling down the annealed aluminum alloy to a temperature below 50° C. Aluminum alloys of the AA5XXX series treated by the annealing process of the present invention are also provided.
    Type: Application
    Filed: February 26, 2019
    Publication date: June 20, 2019
    Applicant: Drexel University
    Inventors: Mitra Lenore Taheri, Daniel Scotto D'Antuono
  • BACKBONE CYCLIZED INHIBITORY PEPTIDES OF MYELOID DIFFERENTIATION FACTOR 88 (MYD88)
    Publication number: 20190185516
    Abstract: Provided are backbone cyclized peptides that interfere with signaling of the intracellular adaptor protein MyD88. Pharmaceutical compositions including these backbone cyclized peptides as well as their use in treatment of multiple sclerosis (MS) and other diseases associated with MyD88 signaling are also disclosed.
    Type: Application
    Filed: June 4, 2017
    Publication date: June 20, 2019
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Gabriel NUSSBAUM, Amnon HOFFMAN, Chaim GILON
  • LOW-NOISE JOSEPHSON JUNCTION-BASED DIRECTIONAL AMPLIFIER
    Publication number: 20190190474
    Abstract: A low-noise directional amplifier includes a first port, a second port, a first coupler and a second coupler. The first port is coupled to a first coupler. The low-noise directional amplifier also includes at least two phase preserving amplifiers, a first phase preserving amplifier connected to the first coupler and a second coupler, and the second phase preserving amplifier connected to the first coupler and the second coupler.
    Type: Application
    Filed: October 15, 2018
    Publication date: June 20, 2019
    Applicant: Yale University
    Inventors: Baleegh Abdo, Katrina Sliwa, Luigi Frunzio, Robert J. Schoelkopf, III, Michel Devoret
  • FROST PREVENTION MACHINE SUPPORT WITH ADJUSTABLE BOTTOM STRUCTURE
    Publication number: 20190186677
    Abstract: The present invention disclosed a frost prevention machine support with an adjustable bottom structure, including a frost prevention machine, a connecting support, a base, and a base bolt. The connecting support is composed of an anti-tilting guide barrel, a fixed strut, a rib plate, and a connecting plate. The base seat formed by assembling a base plate, a rotary plate, a guide rod, and a direction control pin shaft. The base plate and the rotary plate are connected through the guide rod, and the base plates are connected through an upper connecting ring and a lower connecting ring. Each guide rod is mounted in two guide grooves of a corresponding base plate. The base bolt is used for fixedly connecting the connecting support and the base seat.
    Type: Application
    Filed: March 28, 2017
    Publication date: June 20, 2019
    Applicant: JiangSu University
    Inventor: Lili DONG
  • COMPOSITIONS AND METHODS OF MODULATING ABETA PROTEIN
    Publication number: 20190185544
    Abstract: Provided herein are recombinant polypeptides and formulations thereof that can modulate binding of an ApoE protein to an ApoE receptor and/or APP. Also provided herein are methods of administering the recombinant polypeptides and formulations thereof to a subject in need thereof. The subject in need thereof can have or be suspected of having a neurological disease or disorder.
    Type: Application
    Filed: November 5, 2018
    Publication date: June 20, 2019
    Applicant: University of South Florida
    Inventors: DARRELL SAWMILLER, HUAYAN HOU, JUN TAN
  • COMBINATION TAXOID NANOEMULSION WITH IMMUNOTHERAPY IN CANCER
    Publication number: 20190183796
    Abstract: A composition of an omega-3 polyunsaturated fatty acid (PUFA)-taxoid conjugate formulated in an oil-in-water nanoemulsion (NE) drug delivery system in combination with an immune-oncology (IO) agent to enhance therapeutic efficacy in refractory cancers, such as PDAC. A method of treating cancer, by administering an effective amount of a pharmaceutical composition including an omega03 PUFA-taxoid conjugate in combination with an IO agent encapsulated in an NE drug delivery system to a subject in need of treatment, and treating cancer.
    Type: Application
    Filed: December 19, 2018
    Publication date: June 20, 2019
    Applicants: TargaGenix, Inc., The Research Foundation for The State University of New York, Northeastern University
    Inventors: James E. Egan, Mansoor Amiji, Iwao Ojima
  • METHOD OF DIFFERENTIATING NEURAL STEM CELLS OR NEURAL PRECURSOR CELLS INTO DOPAMINE NEURONS
    Publication number: 20190185812
    Abstract: The present invention relates to a method of differentiating neural stem cells or neural precursor cells into dopamine neurons and more particularly, a method of differentiating into dopamine neurons, in which chromosomal stability is maintained by transfecting neural stem cells or neural precursor cells with mRNA of a dopamine neuron-inducing transcription factor under time-based control. The method of differentiating into dopamine neurons, according to the present invention, may enable preparation of mature and functional dopamine neurons having chromosomal stability by synthesizing a dopamine neuron-inducing transcription factor into a mRNA form, which has no risk of genetic modification, and transfecting the synthetic mRNA, unlike existing methods using retroviral vectors, and thus may be usefully used in the clinical field for the treatment of Parkinson's disease.
    Type: Application
    Filed: December 14, 2018
    Publication date: June 20, 2019
    Applicant: Industry-University Cooperation Foundation Hanyang University
    Inventors: Chang-Hwan PARK, Sang Mi Kim
  • STAND FOR A MUSICAL INSTRUMENT
    Publication number: 20190189098
    Abstract: A stand for a musical instrument, the stand comprising: a base; an upright having an upper end and extending upwardly from the base to the upper end; a member comprising a first end portion and a second end portion, the member being mounted on the upper end of the upright between the first end portion and the second end portion; an attachment fitting mounted on the first end portion and configured to releasably attach the musical instrument; and a counterweight mounted on the second end portion for balancing the weight of the musical instrument.
    Type: Application
    Filed: May 15, 2017
    Publication date: June 20, 2019
    Applicant: The Australian National University
    Inventors: John Albert MACKEY, Stephen Murray HOLGATE
  • Memory apparatus having plurality of information storage tables managed by separate virtual regions and control method thereof
    Patent number: 10325672
    Abstract: Disclosed are a memory apparatus having a plurality of information storage tables managed by separate virtual regions and a control method thereof. That is, a fault repair is applied in a memory system having a plurality of information storage tables managed by a separate virtual region, so that the entire information storage space is uniformly used for every region to improve a performance of the entire system and maximize efficiency of the information storage space by utilizing the information storage space.
    Type: Grant
    Filed: April 13, 2017
    Date of Patent: June 18, 2019
    Assignee: Korea University Research and Business Foundation
    Inventors: Seon Wook Kim, Ho Kwon Kim, Jae Yung Jun, Kyu Hyun Choi, Young Sun Han
  • Method for forming a silver/carbon nanocomposite coating
    Patent number: 10323318
    Abstract: Ag/C crystalline nanocomposite films and a method of forming the films with controllable Ag/C molar ratios using a concurrent excimer laser-induced ablation of a silver target and a hydrocarbon gas under a vacuum atmosphere. Metal/Carbon nanocomposites prepared by concurrent irradiation of a metal target, in the presence of a hydrocarbon gas, during an excimer laser induced process.
    Type: Grant
    Filed: October 15, 2018
    Date of Patent: June 18, 2019
    Assignee: King Fahd University of Petroleum and Minerals
    Inventors: Mohammed Ashraf Gondal, Radek Fajgar, Zain Hassan Abdallah Yamani, Xiaofeng Chang
  • Low temperature hydrothermal method for the preparation of LaCOOH nanoparticles
    Patent number: 10322409
    Abstract: A hydrothermal method of preparing uniform, monodisperse ceramic lanthanum hydroxyl carbonate (LaCO3OH) having cherry-blossom-like nanogears and/or nanocubes is described. The method produced a hexagonal crystal with a crystal lattice in which at least on lanthanum ion is substituted with calcium ion. The ceramic nanoparticles produced by the method are good catalyst for the reduction of nitrogen oxides with a hydrocarbon. A method of reducing exhaust gases is described.
    Type: Grant
    Filed: March 5, 2018
    Date of Patent: June 18, 2019
    Assignee: King Fahd University of Petroleum and Minerals
    Inventor: Md. Hasan Zahir
  • Apparatus and method of charging mobile terminal using energy harvesting device
    Patent number: 10326312
    Abstract: An apparatus for charging a mobile terminal includes an energy harvesting device provided in shoes and generating energy generated by a movement of a human body, a charge control module attached to trousers and controlling charging of a mobile terminal using energy harvested by the energy harvesting device, and a resonant coil module wirelessly transmitting energy harvested by the energy harvesting device to the charge control module, wherein the resonant coil module includes a transmission resonant coil unit provided in the shoes and a reception resonant coil unit provided in the trousers, spaced apart from the transmission resonant coil unit by a predetermined distance, and magnetically coupled to the transmission resonant coil unit.
    Type: Grant
    Filed: November 15, 2016
    Date of Patent: June 18, 2019
    Assignee: Industry-Academic Cooperation Foundation, Chosun University
    Inventors: Youn Tae Kim, Min Joo Jeong, Kun Ho Park, Jong Jin Baek, Jang Hyun Lee, Se Woong Kim
  • Device for assisting the crawling of an infant
    Patent number: 10321771
    Abstract: Device for assisting crawling of an infant (2) on a training surface comprising: - a platform (1) comprising a chest supporting surface for supporting a chest of the infant (2) resting on the platform (1) in a prone position, and - rolling elements (9) rotatably mounted on the platform in such a way they can rotate 360 degrees (1) and arranged to be located between the platform (1) and the training surface, wherein the platform (1) is shaped so that, when the rolling elements (9) are in contact with the training surface, the chest supporting surface of the platform (1) is inclined relative to the training surface, so that the pelvis and the legs of the infant (2) are in contact with the training surface.
    Type: Grant
    Filed: July 16, 2015
    Date of Patent: June 18, 2019
    Assignees: Universite Paris Descartes, Centre National de la Recherche Scientifique (CNRS), Ecole Pratique Des Hautes Etudes, San Francisco State University
    Inventors: Marianne Barbu-Roth, Vincent Forma, Caroline Teulier, David Anderson, Joëlle Provasi, Benoist Schaal
  • Methods of making metal-oxides and uses thereof for water treatment and energy applications
    Patent number: 10322948
    Abstract: The disclosure provides relates to compositions and methods for water treatment. It also addresses a method for synthesizing TiO2 (and other metal oxides) with or without dopants. This method enables control over size, phase, morphology and porosity and specific surface area of these materials. The disclosure also provides metal oxide composites that can be used in photocatalysts, photovoltaics, and solar hydrogen applications.
    Type: Grant
    Filed: May 30, 2017
    Date of Patent: June 18, 2019
    Assignee: The Regents of the University of California
    Inventors: David Kisailus, Nichola Kinsinger
  • Methods and devices for high throughput purification
    Patent number: 10324011
    Abstract: Described herein are devices and methods for high throughput purification of particles. In some cases, methods and devices described herein can be used to remove erythrocytes and purify leukocytes and raise the quality of umbilical cord blood and other transplant grafts, thereby significantly improving patient outcomes.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: June 18, 2019
    Assignees: The Trustees of Princeton University, University of Maryland, Baltimore
    Inventors: Joseph D'Silva, Robert H. Austin, James C. Sturm, Curt I. Civin
  • Charge storage material, electrode active material and secondary battery
    Patent number: 10326138
    Abstract: Materials having charge-storing properties and made variously of dipyridine-fused benzoquinones of formula (1) below or derivatives thereof, dipyridine-fused benzoquinones of formula (4) below or derivatives thereof, or dipyridine-fused benzoquinone skeleton-containing polymers are provided. In the formulas, Ar1 and Ar2 are each independently a pyridine ring that forms together with two carbon atoms on a benzoquinone skeleton, or a derivative thereof. When used as electrode active materials, these charge storage materials are capable of providing high-performance batteries possessing a high capacity, high rate characteristics and high cycle characteristics.
    Type: Grant
    Filed: March 9, 2016
    Date of Patent: June 18, 2019
    Assignees: Waseda University, Nissan Chemical Industries, Ltd.
    Inventors: Hiroyuki Nishide, Kenichi Oyaizu, Yuya Kambe, Takuji Yoshimoto
  • System and method for estimating view synthesis distortion
    Patent number: 10326995
    Abstract: System and method embodiments are provided for achieving improved View Synthesis Distortion (VSD) calculation and more accurate distortion estimation of encoded video frames. An embodiment method includes obtaining a depth map value for a video frame and determining a weighting factor for depth distortion in accordance with the depth map value. The weighting factor maps a pixel range of the depth map value to an output function having higher values for closer image objects and lower values for farther image objects. The VSD for the video frame is then calculated as a function of absolute horizontal texture gradients weighted by a depth distortion value and the weighting factor determined in accordance with the depth map value.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: June 18, 2019
    Assignees: Futurewei Technologies, Inc., Santa Clara University
    Inventors: Zhouye Gu, Nam Ling, Chen-Xiong Zhang, Jianhua Zheng
  • Method and system for behavioral monitoring
    Patent number: 10321870
    Abstract: A method of analysis is disclosed. The method comprises: receiving from a mobile device of a subject sensor data and/or device state data, analyzing the data to provide at least one behavioral pattern associated with the subject, comparing the behavioral pattern with a reference behavioral pattern, and estimating the likelihood that the subject is experiencing or is expected to experience an abnormal condition based on the comparison.
    Type: Grant
    Filed: April 30, 2015
    Date of Patent: June 18, 2019
    Assignee: Ramot at Tel-Aviv University Ltd.
    Inventors: Uri Nevo, Keren Zeevy Sela, Asaf Liberman, Dana Erlich, Adam Harel, Jonathan Marton
  • Logic circuit based on thin film transistor
    Patent number: 10326089
    Abstract: The disclosure relates to a logic circuit. The logic circuit includes a n-type thin film transistor and a p-type thin film transistor. Each thin film transistor includes a substrate; a semiconductor layer including nano-scaled semiconductor materials; a source and a drain, wherein the source and the drain are spaced apart from each other, and electrically connected to the semiconductor layer; a dielectric layer covering the semiconductor layer, wherein the dielectric layer includes a normal dielectric layer and an abnormal dielectric layer stacked on one another, and the abnormal dielectric layer is an oxide dielectric layer grown by magnetron sputtering; and a gate in direct contact with the abnormal dielectric layer. The n-type thin film transistor and the p-type thin film transistor share the same substrate and the same gate.
    Type: Grant
    Filed: November 20, 2017
    Date of Patent: June 18, 2019
    Assignees: Tsinghua University, HON HAI PRECISION INDUSTRY CO., LTD.
    Inventors: Yu-Dan Zhao, Yu-Jia Huo, Xiao-Yang Xiao, Ying-Cheng Wang, Tian-Fu Zhang, Yuan-Hao Jin, Qun-Qing Li, Shou-Shan Fan