Patents Assigned to University
  • Patent number: 10322178
    Abstract: Techniques for opening a target tissue using nanodroplets are provided. An exemplary method can include targeting a region of tissue for opening, delivering a plurality of nanodroplets to the region, and applying an ultrasound beam at the region such that the nanodroplets cavitate, or convert to microbubbles that cavitate, thereby causing the target tissue to open.
    Type: Grant
    Filed: August 11, 2014
    Date of Patent: June 18, 2019
    Assignees: The Trustees of Columbia University in the City of New York, The University of North Carolina at Chapel Hill
    Inventors: Chen Chen, Elisa E. Konofagou, Paul Dayton
  • Patent number: 10322221
    Abstract: A method of reducing the concentration of carbon dioxide in blood plasma includes removing blood from a patient and treating or processing at least blood plasma of the blood by flowing the blood plasma on one side of at least one semi-permeable membrane and flowing a dialysate on the other side of the at least one semi-permeable membrane. The dialysate has a concentration of bicarbonate less than the concentration of bicarbonate in the blood plasma before treating the blood plasma and has a composition such that the blood plasma strong ion difference that results from treating the blood plasma in conjunction with an achieved reduction in blood plasma CO2 concentration results in a blood plasma pH that does not change by more than +/?0.5 during treatment.
    Type: Grant
    Filed: January 18, 2014
    Date of Patent: June 18, 2019
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: John Alston Kellum, Jr., Matthew Cove, William J. Federspiel
  • Patent number: 10324068
    Abstract: A method performed by a processing device, the method comprising: obtaining first waveform data indicative of traversal of a first signal through a structure at a first time; applying a scale transform to the first waveform data and the second waveform data; computing, by the processing device and based on applying the scale transform, a scale-cross correlation function that promotes identification of scaling behavior between the first waveform data and the second waveform data; performing one or more of: computing, by the processing device and based on the scale-cross correlation function, a scale factor for the first waveform data and the second waveform data; and computing, by the processing device and based on the scale-cross correlation function, a scale invariant correlation coefficient between the first waveform data and the second waveform data.
    Type: Grant
    Filed: July 18, 2013
    Date of Patent: June 18, 2019
    Assignee: Carnegie Mellon University
    Inventors: Joel B. Harley, Jose M. F. Moura
  • Patent number: 10323173
    Abstract: A method of removing an iron sulfide scale from a surface in fluid communication with a wellbore and/or subterranean formation comprising contacting the iron sulfide scale on the surface with a composition to dissolve the iron sulfide scale in the composition. The composition comprises (a) at least one chelating agent selected from the group consisting of DTPA, EDTA HEDTA, GLDA, CDTA, and MGDA, and salts thereof, and (b) at least one converting agent selected from the group consisting of potassium carbonate (K2CO3), potassium formate (HCOOK), potassium hydroxide (KOH), potassium chloride (KCl), cesium formate (HCOOCs), and cesium chloride (CsCl). In the composition, the weight ratio of (a):(b) lies in the range 7-60:2-20.
    Type: Grant
    Filed: September 7, 2017
    Date of Patent: June 18, 2019
    Assignee: King Fahd University of Petroleum and Minerals
    Inventors: Mohamed Ahmed Nasreldin Mahmoud, Badr Salem Ba Geri, Ibnelwaleed A. Hussein
  • Patent number: 10325654
    Abstract: A resistive memory device and a fabricating method thereof are provided. The resistive memory device includes: a first electrode electrically coupled with a first wire; a second electrode facing the first electrode and electrically coupled with a second wire, the second electrode including an oxygen vacancy reservoir and a contact electrode, and a memory cell including a variable resistive layer and being disposed between the first electrode and the second electrode. The variable resistive layer has a conductive filament, which includes oxygen vacancies and connects the first electrode and the second electrode. The oxygen vacancy reservoir is disposed on the variable resistive layer, and the contact electrode is coupled to the oxygen vacancy reservoir and the second wire. The oxygen vacancy reservoir has a volume or oxidizing power to exchange a limited amount of oxygen ions and oxygen vacancies required for switching the conductive filament with the variable resistive layer.
    Type: Grant
    Filed: December 29, 2017
    Date of Patent: June 18, 2019
    Assignees: Seoul National University R&DB Foundation, SK hynix Inc.
    Inventors: Cheol Seong Hwang, Jaeyeon Lee
  • Patent number: 10326875
    Abstract: A system for use in issuing commands to a plurality of appliances each of a specific one of a plurality of different appliance types includes a smart device adapted to transmit command communications and a plurality of low-energy consuming controllers each adapted to transmit a command to a one of the plurality of appliances of a specific one of the plurality of different appliance types in response to receipt of a command communication originating from the smart device.
    Type: Grant
    Filed: October 6, 2017
    Date of Patent: June 18, 2019
    Assignee: Universal Electronics Inc.
    Inventors: Brandt Thompson, Patrick H. Hayes
  • Patent number: 10322992
    Abstract: Methods of synthesizing cerium oxide and polyaniline nanocomposites, including nanospheres enclosing a hollow core, are specified. Properties of the cerium oxide and polyaniline nanocomposites are described, as well as a method of using the nanocomposites as photocatalysts for the reduction of an aromatic nitro compound using visible light. A method for reusing the nanocomposites as photocatalysts is also discussed.
    Type: Grant
    Filed: December 13, 2016
    Date of Patent: June 18, 2019
    Assignee: King Abdulaziz University
    Inventors: Mohammad W. Kadi, R. M. Mohamed
  • Patent number: 10324034
    Abstract: A self-referencing localized plasmon resonance sensing device and a system thereof are disclosed. The reference optical waveguide element is modified with a noble metal nanoparticle layer. The sensing optical waveguide element is modified with a noble metal nanoparticle layer, which is further modified with a recognition unit. The incident light is guided into the reference and the sensing optical waveguide elements to respectively generate localized plasmon resonance sensor signals. The reference and the sensing optical waveguide elements respectively have a calibration slope. The processor utilizes the calibration slopes to regulate the second difference generated by detecting with the sensing optical waveguide element. The processor utilizes a difference between the first difference, which is generated by detecting with the reference optical waveguide element, and the regulated second difference to obtain a sensor response.
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: June 18, 2019
    Assignee: National Chung Cheng University
    Inventors: Lai-Kwan Chau, Chin-Wei Wu, Chang-Yue Chiang, Chien-Hsing Chen
  • Patent number: 10323286
    Abstract: The present invention provides a set of oligonucleotides to screen for the presence of targeted Salmonella serotypes in enrichment or to characterize presumptive colonies. The set of oligonucleotides includes at least one set of primers and probe for the detection of Salmonella serotype selected from Newport, Heidelberg, Infantis, and Hadar and to discriminate between. These new markers can be used after the initial screening assay described herein as a discrimination assay to differentiate S. Heidelberg from S. Infantis and S. Hadar from S. Newport.
    Type: Grant
    Filed: March 30, 2016
    Date of Patent: June 18, 2019
    Assignee: Texas Techn University System
    Inventors: Marie Bugarel, Kendra Nightingale, Guy Loneragan, Mindy M. Brashears
  • Patent number: 10323221
    Abstract: A device for controlling apical flow to a cell culture includes an apical insert that defines at least one inlet channel extending from an inlet port to an apical feed port and at least one outlet channel extending from an apical effluent port to an outlet port. The apical insert includes a projecting portion configured to extend into a cell culture insert to a depth that is less than a depth of the cell culture insert, and a contact surface configured to maintain a spatial relationship between the projecting portion and the cell culture insert.
    Type: Grant
    Filed: January 5, 2017
    Date of Patent: June 18, 2019
    Assignees: Northeastern University, Massachusetts Institute of Technology
    Inventors: Transon V. Nguyen, Collin D. J. Edington, Emily C. Suter, Rebecca Lyn Carrier, David L. Trumper, Linda G. Griffith
  • Patent number: 10322251
    Abstract: A multi-night titration (MNT) process to find an optimal single therapeutic pressure of a CPAP device. This single therapeutic pressure can then be used on an on-going basis by the patient after the titration period. The MNT process differs from current auto adjusting processes used for titration (or ongoing use) in that the MNT process does not respond locally by adjusting pressures to individual events. With existing devices, the continuous adjustment of supplied air pressure always responds to one or a small number of events and thus fails to compensate for a patient's adaptation thereto, resulting in the supply of a less than optimal therapeutic pressure to the patient. While auto adjusting processes often capture and respond well to short-term and transient conditions, the MNT process of the current disclosure seeks to capture long term trends and find the most suitable average single pressure for a patient.
    Type: Grant
    Filed: March 10, 2014
    Date of Patent: June 18, 2019
    Assignees: Fisher & Paykel Healthcare Limited, New York University
    Inventors: David M. Rapoport, Indu Ayappa, Simei Gomes Wysoski, Sujeewa Wannigama, David Robin Whiting
  • Patent number: 10323007
    Abstract: Described herein are quinazoline-based compounds and formulations thereof. In some embodiments, the compounds and/or formulations thereof can be effective to inhibit and/or kill A. baumannii. Also described herein are methods of treating a subject in need thereof by administering to the subject in need thereof a quinazoline-based compound and/or formulation thereof to the subject in need thereof.
    Type: Grant
    Filed: September 13, 2017
    Date of Patent: June 18, 2019
    Assignee: University of South Florida
    Inventors: Roman Manetsch, Kurt S. Van Horn, Whittney Burda, Lindsey N. Shaw, Renee Fleeman, Megan Barber, David Lawrence Flanigan
  • Patent number: 10322009
    Abstract: A method and system for performing bone fusion and/or securing one or more bones, such as adjacent vertebra, are disclosed.
    Type: Grant
    Filed: July 31, 2015
    Date of Patent: June 18, 2019
    Assignees: H. Lee Moffitt Cancer Center and Research Institute, Inc., University of South Florida
    Inventors: Kamran Aghayev, James J. Doulgeris, Sabrina A. Gonzalez Blohm, Frank D. Vrionis
  • Patent number: 10322284
    Abstract: A system and method for treating nausea and vomiting are provided, including one or more electrodes (10, 12) applied on or under the skin, the electrodes being connected to an external current source (34). The electrodes can be implanted under the skin and connect to internal stimulator electronics (22), which can form a magnetic inductive link to the external current source (34). Alternatively, the electrodes can be placed on the skin and directly linked by wires to the external current source. As a further alternative, the vagus nerve can be directly stimulated in the neck, or the esophagus, stomach, duodenum, or intestines can be directly stimulated by magnetic stimulation. The electrodes can stimulate the vagus nerve in the neck to reduce nausea and vomiting, or can be arranged near the chest or abdomen, so as to stimulate the esophagus, stomach, duodenum or intestines. Because the current source is provided outside the body, it is not necessary to implant batteries or another power supply in the body.
    Type: Grant
    Filed: July 19, 2004
    Date of Patent: June 18, 2019
    Assignee: The John Hopkins University
    Inventors: Ronald P. Lesser, Robert S. Webber
  • Patent number: 10323057
    Abstract: Provided are certain derivatives of amphotericin B (AmB) characterized by reduced toxicity and retained anti-fungal activity. Certain of the derivatives are C16 urea derivatives of AmB. Certain of the derivatives are C3, C5, C8, C9, C11, C13, or C15 deoxy derivatives of AmB. Certain of the derivatives include C3? or C4? modifications of the mycosamine appendage of AmB. Also provided are methods of making AmB derivatives of the invention, pharmaceutical compositions comprising AmB derivatives of the invention, and methods of use of AmB derivatives of the invention.
    Type: Grant
    Filed: October 6, 2014
    Date of Patent: June 18, 2019
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Martin D. Burke, Stephen Davis, Brice E. Uno, Justin Struble, Ian Dailey, Kaitlyn C. Gray, David M. Knapp, Pulin Wang, Nagarjuna Palyam
  • Patent number: 10323017
    Abstract: A method of preventing or reducing the level of degradation of an organic substrate is described, wherein a composition is formed that includes the organic substrate together with an effective amount of a sacrificial base and a diarylamine antioxidant.
    Type: Grant
    Filed: February 5, 2016
    Date of Patent: June 18, 2019
    Assignees: Alma Mater Studiorum—Universita di Bologna, University of Ottawa
    Inventors: Derek A. Pratt, Ronak Mayankbhai Shah, Evan Anthony Haidasz, Luca Valgimigli
  • Patent number: 10327123
    Abstract: A system and method for Machine-to-Machine (M2M) communication over a transmission medium, including a novel random access protocol that is easy to implement, energy efficient, scalable and compatible with the limited-power and low complexity requirements of IoT devices. The proposed protocol utilizes a form of multiple hypothesis testing at the IoT gateway to determine the number of active IoT devices operating in the transmission medium to optimize the power levels of a Successive Interference Cancellation (SIC) receiver in order to distinguish between signals transmitted from different IoT devices on the same time and frequency. The use of beamforming exploits the power and spatial domains without excessively increasing the SIC power levels and address channel access delay problems by reducing the probability of collision and consequently lowering the average back-off delay.
    Type: Grant
    Filed: August 17, 2018
    Date of Patent: June 18, 2019
    Assignee: University of South Florida
    Inventors: Richard Dennis Gitlin, Mohamed Elkourdi, Asim Mazin
  • Patent number: 10321988
    Abstract: A mitral valve prosthesis is percutaneously and/or transapically deployed in at least two stages. In a first stage, a mitral annular ring platform adapted for percutaneous delivery is delivered to and anchored in the mitral valve annulus. In the second stage, a valved-stent mitral valve prosthetic device adapted for percutaneously delivery is delivered to the mitral valve annulus for mounting in the mitral annular ring platform. This approach provides a consistent platform for accepting valved-stent mitral valve prosthetic devices from different vendors to be used.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: June 18, 2019
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Joseph H. Gorman, III, Robert C. Gorman, Matthew J. Gillespie
  • Patent number: 10326803
    Abstract: A system, method and apparatus for network security monitoring, information sharing and collective intelligence between and among at least a first central processing unit and at least a second central processing unit connected together by a network. The system includes a network interface device with hardware-based logic for recognizing and cataloging individual sessions, wherein the network interface card is in communication with the network. The network interface device includes onboard cryptographic key management components with symmetric key algorithms, an onboard packet encryption software module using derived keys to encrypt network packets, and software for storing encrypted copies of network packets as blocks. Third party analyst hardware and software derive keys necessary to retrieve encrypted network packets.
    Type: Grant
    Filed: June 9, 2015
    Date of Patent: June 18, 2019
    Assignee: The University of Tulsa
    Inventor: Michael Haney
  • Patent number: 10322353
    Abstract: Present embodiments are directed toward a dynamic control system for an amusement park ride. The system includes a game server that generates game data describing movement of a virtual vehicle through a virtual environment; a programmable logic controller (PLC) configured to conditionally execute instructions of a dynamic ride profile relative to one or more stored limits to operate physical actions of the ride vehicle; and a dynamic ride profile server communicatively coupled to the game server and the PLC. The dynamic ride profile server is configured to: receive input data, sensor data, and the game data; provide the received data as inputs to one or more physical models to generate a portion of a dynamic ride profile based on the movement of the virtual vehicle through the virtual environment; and provide the portion of the dynamic ride profile to the PLC for conditional execution.
    Type: Grant
    Filed: September 10, 2018
    Date of Patent: June 18, 2019
    Assignee: Universal City Studios LLC
    Inventors: Patrick J. Goergen, Danielle Holstine, Patrick Boyle, Jack Joseph Colletta, Martin Evan Graham