Abstract: The invention provides methods for treating fibrosis and/or cancer in a subject in need thereof. The methods include providing a composition comprising an inhibitor of IL-4/IL-13 receptor function and administering an effective amount of the composition to the subject to treat fibrosis and/or cancer.
Type:
Grant
Filed:
March 15, 2017
Date of Patent:
April 2, 2019
Assignees:
Cedars-Sinai Medical Center, The Board of Trustees of the Leland Stanford Junior University
Inventors:
Ramachandran Murali, Aida Habtezion, Stephen J. Pandol
Abstract: Methods and systems are provided for controlling an electronic device. The method includes acquiring, by a processor of the electronic device, a facial image. The facial image includes a face of a user having one or more eyes. The processor detects a center position of the eye and a pupil position corresponding to a center of a pupil of the eye, determines an eye gaze position based on the center position and the pupil position, analyzes the eye gaze position in consecutively captured facial images, and performs a function associated with a touch event at the eye gaze position in response to determining that the gaze position corresponds to a location of the touch event in the consecutively captured facial images.
Type:
Grant
Filed:
April 27, 2017
Date of Patent:
April 2, 2019
Assignee:
Imam Abdulrahman Bin Faisal University
Inventors:
Dania Ali Abed Aljawad, Ebtesam Jubran Alqahtani, Ghaidaa Mohammad Al-Kuhaili, Nada Mohammed Qamhan, Noof Abdullah Alghamdi
Abstract: The disclosure relates to a method for making fuel cell system. The fuel cell system includes a fuel cell module curved to form a chamber. The fuel cell module includes a container having a number of through holes and a membrane electrode assembly located on the container and cover the number of through holes. The membrane electrode assembly includes a proton exchange membrane having a first surface and a second surface opposite to the first surface, a cathode electrode located on the first surface and an anode electrode located on the second surface. A fuel cell module is at least partially immerged in the fuel and the oxidizing gas is supplied in to the chamber of the fuel cell module.
Type:
Grant
Filed:
December 15, 2015
Date of Patent:
April 2, 2019
Assignees:
Tsinghua University, HON HAI PRECISION INDUSTRY CO., LTD.
Abstract: A wireless system and methods for non-invasive detection of brain injury that includes a detection device for reliable monitoring and analyzing of sleep movement in comparison with normal sleep movement architecture to identify dampened sleep movement patterns indicative of brain injury.
Type:
Grant
Filed:
November 23, 2015
Date of Patent:
April 2, 2019
Assignee:
University of Maine System Board of Trustees
Abstract: Methods for correcting inhomogeneities of magnetic resonance (MR) images and for evaluating the performance of the inhomogeneity correction. The contribution of both transmit field and receiver sensitivity to signal inhomogeneity have been separately considered and quantified. As a result, their negative contributions can be fully corrected. The correction method can greatly enhance the accuracy and precision of MRI techniques and improve the detection sensitivity of pathophysiological changes. The performance of signal inhomogeneity correction methods has been evaluated and confirmed using phantom and in vivo human brain experiments. The present methodologies are readily applicable to correct signal intensity inhomogeneity artifacts produced in different imaging modalities, such as computer tomography, X-ray, ultrasound, and transmission electron microscopy.
Type:
Grant
Filed:
March 14, 2014
Date of Patent:
April 2, 2019
Assignees:
Ohio State Innovation Foundation, Yale University
Inventors:
Jinghua Wang, Zhong-lin Lu, Robert Todd Constable
Abstract: A method of detecting at least one of analyte in an environment (such as in breath) includes providing a structure including nanostructures in contact with titanium dioxide, applying electromagnetic radiation to the structure for a period of time, measuring at least one response and using the measured response to determine the presence of the analyte in the environment.
Type:
Grant
Filed:
September 6, 2014
Date of Patent:
April 2, 2019
Assignee:
University of Pittsburgh—Of the Commonwealth System of Higher Education
Abstract: An electrostatic sensing device comprises an electrostatic sensing module and a control unit electrically connected to the electrostatic sensing module. The electrostatic sensing module comprises a first electrostatic sensing element comprising opposite ends, and two first electrodes. The two first electrodes are separately located on and electrically connected to the two opposite ends of the first electrostatic sensing element. The first electrostatic sensing element is a single walled carbon nanotube or a few-walled carbon nanotube. The control unit electrically is configured to apply a direct voltage to the first electrostatic sensing element and measure a current/resistance of the first electrostatic sensing element.
Type:
Grant
Filed:
December 29, 2015
Date of Patent:
April 2, 2019
Assignees:
Tsinghua University, HON HAI PRECISION INDUSTRY CO., LTD.
Abstract: The fabrication of an implant-supported fixed complete denture involves multiple clinical and laboratory steps. One of the main steps is to provide the patient with an interim fixed prosthesis to evaluate the patient's esthetic and function al needs as well as to enhance the patient's psychology before proceeding to the definitive prosthesis. Different techniques for fabricating interim prostheses have been described in the literature. This disclosure describes a method of fabricating an implant-supported fixed interim prosthesis using self-curing acrylic resin. The interim prosthesis may be used as a blueprint for the definitive implant-supported hybrid prosthesis.
Abstract: A sulfur removal system including a first reactor and a second reactor that are located in series to one another each having an adsorbent that includes cobalt and copper on an activated carbon support, a method of desulfurizing a sulfur-containing hydrocarbon stream via the sulfur removal system, and a method of making the adsorbent. Various embodiments of the sulfur removal system, the desulfurizing method, and the method of making the adsorbent is also provided.
Type:
Grant
Filed:
April 12, 2017
Date of Patent:
April 2, 2019
Assignee:
King Fahd University of Petroleum and Minerals
Inventors:
Tawfik Abdo Saleh Awadh, Saddam Ahmed Al-Hammadi
Abstract: A data access method based on a cloud computing platform, and a user terminal, are provided. The method is performed by a user terminal, and the method includes obtaining an access request for a data ciphertext of the cloud computing platform, the access request including a decryption key, and the decryption key including a user precise identity identifier and a user attribute identifier. The method further includes decrypting the data ciphertext into a data plaintext, in response to the user precise identity identifier belonging to an identity identifier set included in an access structure of the data ciphertext and/or in response to the user attribute identifier belonging to a user attribute identifier set included in the access structure of the data ciphertext.
Type:
Grant
Filed:
May 24, 2016
Date of Patent:
April 2, 2019
Assignees:
TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED, Hunan University
Abstract: The present invention relates to techniques for lowering friction between moving surfaces of, for example, an internal combustion engine. Friction reduction is achieved by adding texture modifications to surfaces that come in contact with each other. Texture modifications that reduce friction in accordance with the present invention include dimples of varying geometries and depths ion the surfaces of components. The present invention also relates to the fabrication technique for applying the textures to the surfaces. In another embodiment, the patterned soft mask is applied onto a large surface (flat or curved including cylindrical rollers surfaces) to be followed by electrochemical etching to imprint the textures onto the component. And, in another embodiment, a diamond-like-carbon (DLC) film may be applied to the turbine component to also reduce friction.
Type:
Grant
Filed:
February 21, 2012
Date of Patent:
April 2, 2019
Assignee:
The George Washington University
Inventors:
Stephen M. Hsu, Yang Jing, Yufei Mo, Dongyun Hua, Ming Chen
Abstract: One aspect of the invention provides a wearable device including: at least one compliant region adapted and configured to be placed over a joint of a subject and at least two flexible but less compliant regions coupled to opposite ends of the compliant region. Another aspect of the invention provides a wearable robotic device including a wearable device as described herein and at least one actuator adapted and configured to move the flexible but less compliant regions relative to each other.
Type:
Grant
Filed:
February 27, 2015
Date of Patent:
April 2, 2019
Assignee:
Drexel University
Inventors:
Andrew Cohen, Genevieve Dion, Mark Winter, Eric Wait, Michael Koerner
Abstract: A balanced planetary gearbox including an assembly having an input stage and an output stage. The assembly includes two grounds, each with ground rollers and ground rings. The two grounds are fixedly attached to one another. The assembly includes a sun gear and planet sub-assemblies between the two grounds. The planet sub-assemblies include at least one input planet gear and one output planet gear. The sun gear and the input planet gears include rollers. An abutment of rollers in the gearbox keeps the sun gear and the planet gears in alignment. The output gear meshes with an output ring disposed in between the two ground rings, such that a combination of the at least one input planet gears from each of the plurality of planet sub-assemblies provides a structural symmetry to the planetary gearbox.
Type:
Grant
Filed:
June 8, 2015
Date of Patent:
April 2, 2019
Assignee:
Northeastern University
Inventors:
Elias Brassitos, Brian Weinberg, Qingchao Kong, Constantinos Mavroidis
Abstract: Methods, systems, and devices are disclosed for fabricating and implementing nanoscale and microscale structured carriers to provide guided, targeted, and on-demand delivery of molecules and biochemical substances for a variety of applications including diagnosis and/or treatment (theranostics) of diseases in humans and animals. In some aspects, a nanostructure carrier can be synthesized in the form of a nanobowl, which may include an actuatable capping particle that can be opened (and in some implementations, closed) on demand. In some aspects, a nanostructure carrier can be synthesized in the form of a hollow porous nanoparticle with a functionalized interior and/or exterior to attach payload substances and substances for magnetically guided delivery and controlled release of substance payloads.
Type:
Grant
Filed:
June 15, 2015
Date of Patent:
April 2, 2019
Assignee:
The Regents of the University of California
Inventors:
Ratneshwar Lal, Preston B. Landon, Alexander Mo
Abstract: The present disclosure provides compositions for in vivo imaging of hydrogen peroxide; and methods for detecting hydrogen peroxide in vivo. The compositions and methods find use in various diagnostic applications, which are also provided.
Type:
Grant
Filed:
July 5, 2017
Date of Patent:
April 2, 2019
Assignee:
The Regents of the University of California
Inventors:
Christopher J. Chang, Alexander R. Lippert
Abstract: Systems and methods for designing and/or using radio frequency (“RF”) pulses for in-vivo MRI applications, where the RF pulses are robust against errors due to physiological motion of organs during the respiratory cycle. For example, RF pulses are designed based on multi-channel B1+ maps correlated to different positions of the respiratory cycle.
Type:
Grant
Filed:
April 24, 2015
Date of Patent:
April 2, 2019
Assignee:
Regents of the University of Minnesota
Inventors:
Sebastian Schmitter, Pierre-Francois van de Moortele, Xiaoping Wu, Kamil Ugurbil
Abstract: A heat-assisted magnetic recording media structure with exchange-coupled composite layer structure may be utilized in a data storage device. The heat-assisted magnetic recording disk structure can have a FePt-based layer as a storage layer and a FePt-based or a CoPt-based magnetic layer with higher Curie temperature as a write layer. The interface between the write layer and the storage layer may be separated by an exchange control layer. The composite structure can be optimized to reduce jitter for high density data storage by tuning the exchange coupling between the write layer and storage layer.
Type:
Grant
Filed:
September 22, 2017
Date of Patent:
April 2, 2019
Assignees:
Seagate Technology LLC, Regents of the University of Minnesota
Abstract: The magnetic polymer nanocomposite for removal of divalent heavy metal ions from water is magnetic nanocomposite having a core of magnetite (Fe3O4) in a shell of branched polyhydroxystyrene (BHPS), designated as Fe3O4@BHPS. The nanocomposite is synthesized by co-precipitation in alkali solution. Testing showed the nanocomposite reached 93% and 80% Pb(II) and Cd(II) adsorption, respectively, in 30 minutes, attaining equilibrium in 120 minutes. The maximum adsorption capacities of Pb(II) and Cd(II) at 298K were 186.2 and 125 mg/g, respectively. After adsorption, the nanocomposite with the heavy metal(s) adsorbed thereto was easily removed from aqueous solution by application of a magnetic field.
Type:
Grant
Filed:
September 20, 2018
Date of Patent:
April 2, 2019
Assignee:
King Saud University
Inventors:
Ayoub Abdullah Alqadami, Moonis Ali Khan, Zeid Abdullah Alothman, Ibrahim Hotan Alsohaimi, Masoom Raza Siddiqui, Ayman A. Ghfar
Abstract: A new and distinct Berberis cultivar named ‘NCBT1’ is disclosed, characterized by purple foliage and a distinctively compact and round plant habit. Plants have very low female fertility. The new variety is a Berberis, normally produced as an outdoor garden plant.