Abstract: A pressure chamber has a chamber wall. The chamber wall includes a sensor integrated within the chamber wall, wherein the sensor integrated in the chamber wall comprises defects. A method of determining an effect of pressure on a material is further described. The method includes applying pressure to a material within a pressure chamber and to a pressure chamber wall of the pressure chamber, where the pressure chamber wall has defects. A signal from the defects is sensed while the material and the pressure chamber wall are under pressure. A property of the material is determined based on the sensed signal.

Abstract: A method for disinfecting explants of Kadsura coccinea stems with buds and a method for directly inducing rapid proliferation of sterile buds by using the explants of Kadsura coccinea stems with buds involve processes such as selection, treatment and disinfection of explants, primary culture, subculture proliferation culture. The problem of difficulty in tissue culture and primary culture of Kadsura coccinea stems is solved, and the advantages include low contamination rate of explants, high propagation rate and robust proliferation of axillary buds. This allows obtaining sterile axillary buds of Kadsura coccinea through tissue culture, and provides support for tissue culture, rapid propagation and factory seedling of Kadsura coccinea in the future.

Abstract: There is described a method for the preparation of a hyperpolarised agent, wherein said agent comprises at least one —N?, —O? or —S? moiety (optionally protonated) and a secondary binding site; said method comprising: (i) preparing a fluid containing a polarisation transfer precatalyst and parahydrogen; (ii) introducing a co-ligand to interact with the transfer precatalyst to form a polarisation transfer catalyst; (iii) applying a magnetic field or radio frequency excitation to (ii), such that hyperpolarisation is transferred from parahydrogen to a target molecule; (iv) introducing a target molecule containing at least at least one —N?, —O? or —S? moiety, in conjunction with a secondary binding to form a hyperpolarised agent; wherein the co-ligand is selected from the group consisting of one or more of a sulfoxide, a thioester, a phosphine, an amine, CO, an isonitrile and a nitrogen heterocycle.

Abstract: Certain embodiments are directed to methods for making programmable bioinspired nanoparticles (P-BiNP). Nanoparticles are coated with a cell membrane derived from a cell stimulated to express or overexpress a protein identified as being expressed in a target cell, forming a homotypic and organ targeted nanoparticle delivery vehicle.

Abstract: Disclosed is a nonincendive electrolyte for lithium secondary battery, the electrolyte using an organic solvent mixture including a first solvent containing fluorine and sulfur, a second solvent that is a linear carbonate-based compound containing fluorine, a third solvent that is a linear ester-based compound containing fluorine, and a fourth solvent that is a cyclic carbonate-based compound. Thus, the electrolyte is nonflammable or flame-retardant, thereby preventing a lithium secondary battery from catching on fire or exploding. That is, the electrolyte greatly improves the safety of a lithium secondary battery, allows the high voltage charge of a lithium secondary battery, and prevents the degradation of battery performance of a lithium secondary battery. In addition, a lithium secondary battery including the electrolyte is disclosed.

Abstract: A method for enhancing the performance of pentacene organic field-effect transistor (OFET): an n-type semiconductor thin film was set as a buffer layer between pentacene and polymer electret in the OFET with the structure of gate-electrode/insulating layer/polymer/pentacene/source (drain) electrode. The thickness of n-type organic buffer layer is 1˜100 nm. The induced electrons at the interface lead to the reduction of the height of the hole-barrier formed at the interface, thus effectively reducing the programming/erasing (P/E) gate voltages of pentacene OFET. The widened distribution region of positive space charges caused by ionized donors in n-type organic buffer layer effectively restricts the back-transfer of holes from polymer to pentacene, thus improving the performance of pentacene OFET, such as the P/E speeds, P/E endurance and retention characteristics.

Abstract: The disclosed embodiments relate to a system that provides a polymer heat exchanger with internal microscale flow passages. The system includes a set of plates comprised of a polymer that includes internal microscale flow passages, which are configured to carry a liquid. The set of plates is organized into a stack, wherein consecutive plates in the stack are separated by fins to form intervening air passages. The system includes a liquid flow pathway, which flows from a liquid inlet, through the internal microscale flow passages in the stack of plates, to a liquid outlet. It also includes an airflow pathway, which flows from an airflow inlet, through the intervening air passages between the consecutive plates in the stack of plates, to an airflow outlet. The liquid flow pathway flows in a direction opposite to a direction of the airflow pathway to provide a counterflow design that optimizes heat transfer between the liquid flow pathway and the airflow pathway.

Abstract: A method for fabricating a resorbable scaffold for regeneration of meniscal tissue is disclosed. The method includes fabricating a polymer filament network using 3D printing in accordance with a digital model of the polymer filament network, such that the polymer filament network will include a first plurality of layers comprising the circumferentially-oriented filaments alternating with a second plurality of layers comprising the radially-oriented filaments, the polymer filament network having a three-dimensional shape and geometry between a first layer and a second layer which is substantially the same as a three-dimensional shape and geometry of the resorbable scaffold.

Abstract: The present disclosure relates to the field of biotechnology, and in particular, to a composite formulation and the use thereof for preparing a drug for treating a tumor. The effective components of the composite formulation of the present disclosure at least comprise a compound having a structural formula shown in Formula I and an EZH2 inhibitor. In terms of the clinical application for tumours, the present disclosure finds that a low dose of the compound having the structural formula shown in Formula I can enhance the therapeutic effects of the EZH2 inhibitor DZNEP and, when used in combination, can reduce the dosage of the EZH2 inhibitor DZNEP by ? whilst ensuring pharmaceutical effectiveness, being an effective combination therapeutic solution.

Abstract: A switched-capacitor DC-DC voltage converter and a control method thereof. The switched-capacitor DC-DC voltage converter comprises at least one switch array, comprising a capacitor and at least one switch group, wherein the switch group comprises a plurality of power switches connected to one another in parallel, and one end of the capacitor is electrically connected to the switch group; and a control circuit, converting an input control signal into a control signal set, and outputting the control signal set to the switch group, and the control signal set comprises a plurality of control signals with phase delayed sequentially and the duty cycle reduced sequentially.

Abstract: A variable thickness rim structure made of carbon fiber composite includes an outer ply block, that is paved as an outer side of the rim structure; an upper ply block, that is paved as an upper part of an inner side of the rim structure; a lower ply block, that is paved as a lower part of the inner side of the rim structure; a filling ply block, that is paved among the outer ply block, the upper ply block, and the lower ply block, where a first end of the upper ply block and a first end of the lower ply block extend inwards to form an annular connecting flange; a second end of the upper ply block extends upwards and a second end of the lower ply block extends downwards to form a rim ring together with the outer ply block.

Abstract: Provided are compositions and methods for determining an imprinting status of a gene subject to parent-of-origin, monoalleleic expression in a subject, and for using the information derived therefrom to detect a presence of and/or a susceptibility to a medical condition associated with monoallelic expression in a subject, predict a susceptibility to future development of a medical condition prior to the onset of any symptoms, monitor the development of such a medical condition and/or the effectiveness of a treatment, and for treating such a medical condition. In some embodiments, a composition for use in the disclosed methods is nucleic acid array, which in some embodiments can include one or more interrogatable nucleotide molecules, wherein the interrogatable nucleotide molecules are designed to allow identification of the DNA methylation status of one or more imprint control regions (ICRs) that regulate one or more genes subject to monoalleleic expression in subjects.

Abstract: A method for removing recalcitrant organic compounds from water includes exposing water to an oxidizing agent, thereby reducing an amount of at least some classes of dissolved organic matter in the water and adsorbing at least some of the remaining dissolved organic matter in the water onto a porous adsorbent, resulting in adsorbed organic matter on the porous adsorbent. The method includes thermally treating the adsorbed organic matter on the porous adsorbent to remove and degrade the adsorbed organic matter.

Abstract: A method for determining a quality of a friction stir welded seam is described. The method involves applying an impact to a welded plate and comparing its damping capacity with the damping capacity of a geometrically equivalent defect-free plate. Damping capacities that differ by a small percent difference indicate that the welded plate is also defect-free. This method is particularly advantageous when dealing with small defects, which produce miniscule changes in natural frequency which may not be measureable.

Abstract: Various embodiments provide for deep learning-based architectures and design methodologies for an orthogonal frequency division multiplexing (OFDM) receiver under the constraint of one-bit complex quantization. Single bit quantization greatly reduces complexity and power consumption in the receivers, but makes accurate channel estimation and data detection difficult. This is particularly true for OFDM waveforms, which have high peak-to average (signal power) ratio in the time domain and fragile subcarrier orthogonality in the frequency domain. The severe distortion for one-bit quantization typically results in an error floor even at moderately low signal-to-noise-ratio (SNR) such as 5 dB. For channel estimation (using pilots), various embodiments use novel generative supervised deep neural networks (DNNs) that can be trained with a reasonable number of pilots. After channel estimation, a neural network-based receiver specifically, an autoencoder jointly learns a precoder and decoder for data symbol detection.

Abstract: A health early warning system for passengers on a train in an outdoor air polluted environment and a method thereof are provided. The system comprises an air quality monitoring station data acquisition module, a train data acquisition module, a train air pollution prediction module, and a train air environment early warning module; the air quality monitoring station data acquisition module acquires data of air quality monitoring stations and uploads the data to the train air pollution prediction module; the train data acquisition module acquires data of the train and uploads the data to the train air pollution prediction module; the train air pollution prediction module performs short-term prediction on air pollution of the train and uploads a result of the short-term prediction to the train air environment early warning module; and the train air environment early warning module performs early warning on the health of the passengers on the train.

Abstract: A harmonic light-generating metasurface includes a base substrate and a plurality of structures, that include nonlinear material, that are disposed in a pattern on a surface of the base substrate. Each structure of the plurality of structures individually supports a magnetic dipole mode. An electromagnetic field enhancement of the magnetic dipole mode induces generation of a harmonic signal by the plurality of structures. Alternatively, a harmonic light-generating metasurface, includes a base substrate, a supporting substrate that includes a nonlinear material, and a plurality of paired structures disposed in a pattern on a surface of the supporting substrate. Each paired structure, of the plurality of paired structures, collectively supports a toroidal dipole mode. An electromagnetic field enhancement of the toroidal dipole mode penetrates the supporting substrate to induce generation of a harmonic signal by the supporting substrate.

Abstract: A method for isolating one or more distinct analyte component from a cell sample is disclosed, as well as processes for testing and analyzing the distinct analyte components. The distinct analyte components include: (i) a total protein fraction; (ii) a plasma membrane protein fraction; (iii) a total RNA fraction; (iv) a cytosolic RNA fraction; (v) a cytosolic protein fraction; (vi) a nuclear RNA fraction; (vii) a nuclear protein fraction; (viii) a chromatin fraction comprising genomic DNA (gDNA); (ix) a gDNA markers fraction. This method involves the use of microfluidic device having a cell capture component and a nucleic acid entanglement component, where the cell capture component includes a cell capture array having a plurality of cell capture micropillars, where the nucleic acid entanglement component includes a nucleic acid entanglement array having a plurality of nucleic acid entanglement micropillars, and where the microfluidic device operates under continuous flow conditions.

Abstract: In some embodiments, an apparatus includes a volatile memory, a non-volatile memory, a first processor coupled to the non-volatile memory and configured to receive a data set associated with an object and user information associated with a spatial position of a user in a multi-user virtual (IMVR) environment, and a second processor coupled to the volatile memory, the second processor configured to render an instance of the portion of the object in the IMVR environment from a perspective of the user based on the spatial position of the user. The first processor is configured to generate a look-up table (LUT) based on a set of inputs received from a user. The second processor is configured to render, based on the LUT and information related to a manipulation by a user, an updated instance of the portion of the object that manifests an effect of the manipulation in the IMVR environment.

Abstract: Aspects of the present application relate to techniques of diagnosing whether a pathogen (e.g., SARS-CoV-2) is present in a subject using infrared (IR) spectroscopy and machine learning techniques. The techniques use spectral data obtained from performing IR spectroscopy on a biological sample (e.g., saliva or nasal sample, or genetic material extracted therefrom) to generate a set of feature values. The feature values are provided as input to a machine learning model to obtain output indicating whether the pathogen is present in the biological sample. The output of the machine learning model may be used to determine a diagnosis result for a subject.