Abstract: A method of controlling a motor may include receiving command data indicating only a desired torque and/or force for the motor and including no torque and/or force or current feedback data from the motor. Based on the command data and at least one motor characteristic and no separate torque and/or force or current feedback data, a voltage signal corresponding to a desired motor current to produce the desired torque and/or force may be generated. A control signal configured to provide the motor with the desired motor current may be generated using only the voltage signal as an input. The motor may be controlled by inputting the control signal to the motor, and the inputting may cause the motor to output substantially the desired torque and/or force.

Abstract: Compositions and methods for treating, inhibiting, and/or preventing pain, particularly neuropathic pain, are provided.

Abstract: Methods are disclosed for determining a prognosis of a test patient following or during a surgical procedure. In some embodiments, the disclosed methods comprise forming a test data vector characterizing concurrent measures of mean arterial pressure (MAP), bispectral index (BIS), and standard minimum alveolar concentration (MAC) of the test patient from sequential time intervals during the surgical procedure. A K-means clustering procedure is performed on the test data vector and a plurality of reference data vectors characterizing concurrent MAP, BIS, and MAC measures for sequential time intervals during surgical procedures from reference patients with known clinical outcome. A prognosis of one or more post-surgical outcomes of the test patient is determined based on the known surgical outcome of reference patients in the cluster including the test data vector.

Abstract: Described herein are a viscous drag reduction apparatus and a method. The apparatus includes a pair of rollers connected to a supporting surface on a roof of the vehicle, a belt having a frictional surface and partially wrapped around the pair of rollers, such that the pair of rollers allow the belt to rotate in response to an air flow generated around the vehicle when the vehicle is in motion, the pair of rollers having a length in an axial direction that is at least as long as a width of the belt, an assembly of the pair of rollers and the belt being at least partially recessed with respect to a top line of the roof, and a reverse flow cover connected to the front end of the roof of the vehicle to block an air back flow generated by the belt when rotating.

Abstract: The present invention discloses a method for direct transformation of exogenous DNA into resting spores of Aspergillus niger independent of mediators. The method includes three steps of culture of Aspergillus niger and collection of spores, pretreatment of Aspergillus niger spores, and electroporation of Aspergillus niger spores by using HDEN method, to obtain Aspergillus niger spores with introduction of plasmids to be transformed. In the present invention, non-germinated spores are used as a starting material for introduction of an exogenous molecule, and exogenous DNA is introduced into the resting spores of Aspergillus niger by employing the HDEN electrotransformation technique, whereby the complex step of spore germination is omitted, and steps of protoplast preparation or Agrobacterium-mediated transformation in conventional methods etc. are omitted.

Abstract: A bonding material (10) of the present invention includes an amorphous silver film (12).

Abstract: We have discovered that administering anti-ceramide antibody treats and prevents an array of diseases mediated by cytolytic T lymphocyte (CTLs)-induced killing and by damage to endothelial microvasculture, including radiation-induced GI syndrome, Graft vs. Host diseases, inflammatory diseases and autoimmune diseases. We have also discovered new anti-ceramide monoclonal antibodies, that have therapeutic use preferably in humanized form to treat or prevent these diseases.

Abstract: The disclosure provides for single amplification and double amplification methods for preparing nucleic acid samples for sequencing.

Abstract: A solar simulator filter that includes a flexible substrate and one or more layers of oxide materials, e.g. fluorine-doped tin oxide and indium-doped tin oxide, wherein a thickness of said layers is no more than 500 nm, and wherein the solar simulator filter generates a spectral output that closely matches a solar irradiance spectrum. Various embodiments of the solar simulator filter and a method of fabricating thereof is described.

Abstract: The described invention provides pharmaceutical compositions and methods for treating chronic non-healing wounds. The pharmaceutical compositions of the described invention comprise a granulated sugar and a hydrogel biomaterial.

Abstract: The present invention provides a compound having the structure of the instant invention of a pharmaceutically acceptable salt or ester thereof, methods of preparing the same, and methods of treating a subject with compounds of the instant invention in combination therapies.

Abstract: Novel three-dimensional molecular clusters and methods of their synthesis are provided. The three-dimensional molecular clusters may be perfunctionalized polyhedral boranes and carboranes. The three-dimensional clusters may be configured to manipulate the photophysical properties of other materials, including, for example, for use as photooxidants or as components in organic light-emitting diode materials. Methods are also provided for synthesizing and perfunctionalizing such three-dimensional clusters. The three-dimensional clusters may also be configured for use as organomimetic materials.

Abstract: The present invention is related to diagnostic, treatment and compound screening methods related to dry age-related macular degeneration (dry AM D). In select embodiments, the methods comprise determining expression or activity levels of NAD-dependent deacetylase sirtuin-1 (SI RT-1), AM P-activated protein kinase (AM PK), poly(adenosine diphosphate ribose) poly-merase-2 (PARP2), peroxisome proliferator-activated receptor-gamma coactivator 1-alpha (PGC-I?) and/or mRNA levels of RAC-gamma serine/threonine-protein kinase (AKT3). In general, higher levels of PARP2, lower levels of PGC-I? or AKT3 and/or higher acetylation levels of PGC-I? in the samples are indicative that the subject or cells from which the samples are obtained are susceptible or are suffering from dry AMD.

Abstract: A closed loop system for the calibration of a multiphase meter, such as a multiphase flow meter or water cut meter, and a method of employing the system in calibration of multiphase meters in crude oil production processes. The system includes an oil and water separation vessel, oil and water flow meters, valves, pumps, and a single phase calibration unit. The system employs a two-step calibration process. First internal single phase oil and water meters are calibrated using the single phase calibration unit; subsequently multiphase meter calibration is achieved using the two precalibrated single phase flow meters.

Abstract: According to some aspects, a waveform processor is provided for control of quantum mechanical systems. Some embodiments of the waveform processor may be used to control quantum systems used in quantum computation, such as qubits. According to some embodiments, a waveform processor may include a first sequencer configured to sequentially execute master instructions according to a defined order and output digital values in response to the executed master instructions, and a second sequencer coupled to the first sequencer and configured to generate analog waveforms at least in part by transforming digital waveforms according to digital values received from the first sequencer. The analog waveforms may be applied to a quantum system. In some embodiments, the waveform processor may further include a waveform analyzer configured to integrate analog waveforms received from a quantum system and output results of said integration to the first sequencer.

Abstract: In one aspect, the invention provides methods of inhibiting the effects of MASP-2-dependent complement activation in a living subject. The methods comprise the step of administering, to a subject in need thereof, an amount of a MASP-2 inhibitory agent effective to inhibit MASP-2-dependent complement activation. In some embodiments, the MASP-2 inhibitory agent inhibits cellular injury associated with MASP-2-mediated alternative complement pathway activation, while leaving the classical (C1q-dependent) pathway component of the immune system intact. In another aspect, the invention provides compositions for inhibiting the effects of lectin-dependent complement activation, comprising a therapeutically effective amount of a MASP-2 inhibitory agent and a pharmaceutically acceptable carrier.

Abstract: Particular aspects of the present invention provide pharmaceutical compositions comprising isoprenoid-based compounds (e.g., farnesol and/or farnesol analogs or derivatives) or dehydroisoprenoid-based compounds, and novel methods for using same in treating (e.g., suppressing): alcohol withdrawal syndrome and associated neurological symptoms (e.g., depression, tremor, anxiety, autonomic hyperactivity (e.g., sweating, increased blood pressure, tachycardia), hallucinations, alcohol withdrawal seizures, delirium tremens (DT), and memory loss); or for treating in treating convulsive seizure (e.g., epileptic seizure, etc.).

Abstract: A floating buoy includes a buoy hull having a tower that extends outwardly from the hull. A plurality of sensors are mounted either on the buoy hull, within the buoy hull, and/or on the tower. The plurality of sensors includes at least one met-ocean sensor, at least one ecological sensor, and at least one wind speed measurement sensor. The floating buoy further includes an autonomous power system that is configured to provide electrical power to each of the plurality of sensors. The wind speed measurement sensor may be a Light Detection and Ranging (LiDAR) wind speed measurement sensor, a surface level wind speed sensor, an ultrasonic wind speed sensor, or SODAR.

Abstract: A method for synthesizing 3-oxolupenal nanoparticles including isolating 3-oxolupenal from a fraction of Nuxia oppositifolia plant, reducing the 3-oxolupenal to obtain a powder of 3-oxolupenal, dissolving the powder of 3-oxolupenal in methanol to form a first solution, adding the first solution to boiling water to form a second solution, sonicating the second solution, and freeze-drying after sonication to obtain the synthesized 3-oxolupenal nanoparticles. The synthesized 3-oxolupenal nanoparticles exhibited cytotoxic effects and antimicrobial effects.

Abstract: Host cells that are engineered to produce benzylisoquinoline alkaloid (BIAs) precursors, such as norcoclaurine (NC) and norlaudanosoline (NL), are provided. The host cells may have one or more engineered modifications selected from: a feedback inhibition alleviating mutation in a enzyme gene; a transcriptional modulation modification of a biosynthetic enzyme gene; an inactivating mutation in an enzyme; and a heterologous coding sequence. Also provided are methods of producing a BIA of interest or a precursor thereof using the host cells and compositions, e.g., kits, systems etc., that find use in methods of the invention.