Abstract: The custom-fitting collar sleeve backing for commercial hip prostheses includes a base and a top portion, the top portion being connected to the base. The base has a bottom surface defining an aperture. The aperture of the bottom surface is dimensioned and configured for receiving the neck portion of a hip prosthesis. The bottom surface of the base may have a beaded topology. The top portion includes a shoulder portion defining an aperture. The aperture of the shoulder portion includes an outwardly extending annular flange and is configured for fitting the cylindrical shaft of the neck portion of the hip prosthesis.
Abstract: This invention discloses devices and methods for high throughput skin sensitization detection. The devices comprise a microfabricated chamber comprising a region having one or more input channels and an outlet, and a face suitable for mounting a skin tissue and in fluidic communication with the region. The devices can be used in the methods for determining a prognosis of sensitization in an animal subject and identifying compounds that do not cause sensitization and thus are suitable for preparing cosmetic compositions.
Type:
Grant
Filed:
August 10, 2012
Date of Patent:
February 19, 2019
Assignee:
Rutgers, The State University of New Jersey
Inventors:
Tim Maguire, Martin L. Yarmush, Rene S. Schloss, Bhaskar Mitra, Rohit Jindal, Mehdi Ghodbane
Abstract: Compositions having a drug-loaded microparticle and bone cement and methods of making such compositions are disclosed. Also disclosed are methods of employing such compositions for the treatment of injected joint spaces and bone disease.
Type:
Grant
Filed:
September 29, 2014
Date of Patent:
February 19, 2019
Assignee:
Loma Linda University
Inventors:
Victoria Maskiewicz, Gary Botimer, Serkan Inceoglu
Abstract: A method of producing a reactive powder includes providing a bulk structure of reactive material comprising a first reactant and a second reactant, the bulk structure having a preselected average spacing between the first and the second reactants; and mechanically processing the bulk structure of reactive material to produce a plurality of particles from the bulk structure such that each of the plurality of particles comprises the first and second reactants having an average spacing that is substantially equal to the preselected average spacing of the bulk structure of reactive material. The first and second materials of the plurality of particles react with each other in an exothermic reaction upon being exposed to a threshold energy to initiate the exothermic reaction and remain substantially stable without reacting with each other prior to being exposed to the threshold energy.
Abstract: A process is provided for precise self-assembly and re-arrangement of a three-dimensional terpyridine-based coordination complex. A plurality of terpyridine-containing ligands are reacted with at least one metal ion, in a pre-selected molar ratio, to form a self-assembled three-dimensional terpyridine-based coordination complex having a first configuration. A triggering event, such as exposure to light or dilution, causes the coordination complex to re-arrange to form at least two smaller, substantially identical, three-dimensional terpyridine-based coordination complexes, each having a second configuration that is different from the first configuration. Upon application of a second triggering event, such as concentration, the re-arrangement is reversed.
Type:
Grant
Filed:
February 2, 2016
Date of Patent:
February 19, 2019
Assignee:
The University of Akron
Inventors:
George R. Newkome, Charles N. Moorefield, Tingzheng Xie, Xiaocun Lu
Abstract: The present invention includes a method and an apparatus for determining the viscosity of a fluid. The apparatus comprising that includes a microchannel connected to a glass capillary in fluid communication with the microchannel, a digital camera positioned with respect to the glass capillary to capture two or more images of a fluidic slug as a fluid travels within the glass capillary, and a processor communicably coupled to the digital camera that determines a viscosity of the fluid based on the two or more digital images.
Abstract: Compounds are provided that can exhibit anti-cancer and/or anti-inflammatory properties, in some aspects, methods of treating an inflammatory disease or a hyperproliferative disease, such as cancer, with the compounds are provided.
Type:
Grant
Filed:
March 13, 2014
Date of Patent:
February 19, 2019
Assignee:
Board of Regents, The University of Texas System
Inventors:
Richard J. Ford, Jr., William G. Bornmann, Ashutosh Pal, Lan V. Pham, Zhenghong Peng, David Maxwell, Archito Tamayo
Abstract: The invention relates to the field of flow cytometry and more particularly to a panel of antibody reagents conjugated to fluorescent compounds. Provided are reagent compositions, comprising at least eight distinct fluorochrome-conjugated antibodies comprising a set of at least there identification antibodies for the identification of a leukocyte population of interest and at least four characterization antibodies for further characterization and/or classification of said leukocyte population. Also provided are kits and methods related to the reagent compositions.
Type:
Grant
Filed:
December 20, 2017
Date of Patent:
February 19, 2019
Assignee:
Erasmus University Medical Center Rotterdam
Inventors:
Jacobus Johannes Maria van Dongen, Jose Alberto Orfao de Matos Correia e Vale, Juan Alejandro Flores-Montero, Julia Maria Almeida Parra, Vincent Henricus Johannes van der Velden, Sebastian Böttcher, Andrew Craig Rawstron, Ruth Mary de Tute, Ludovic Bernard Simon Lhermitte, Vahid Asnafi, Ester Mejstrikova, Tomasz Szczepanski, Paulo Jorge Monteiro Da Silva Lucio, Marta Martín Ayuso, Carlos Eduardo Pedreira
Abstract: A normally-off, heterojunction field effect transistor includes an intrinsic cubic-phase gallium nitride (c-GaN) substrate and an aluminum gallium nitride (AlGaN) capping layer disposed on the intrinsic c-GaN substrate. The AlGaN capping layer includes a first sublayer of intrinsic c-phase AlxGa1-xN disposed on the c-GaN substrate, wherein the first sublayer is of a first thickness; a second sublayer of doped c-phase AlxGa1-xN disposed on the first sublayer, and wherein the second sublayer is of a second thickness and is doped with a dopant. An insulating layer is disposed on the AlGaN capping layer, wherein the insulating layer is of a fourth thickness. A source electrode, a drain electrode, and a gate electrode are positioned adjacent to and on top of the insulating layer, respectively.
Type:
Grant
Filed:
September 13, 2017
Date of Patent:
February 19, 2019
Assignee:
Board of Trustees of the University of Illinois
Inventors:
Can Bayram, Ryan William Grady, Kihoon Park
Abstract: The present invention provides a common-mode signal absorber, which comprises an impedance-matching network and a common-mode signal reflection circuit. A differential-mode signal is inputted into input ends of the impedance-matching network, and outputted from output ends of the common-mode signal reflection circuit. When a common-mode signal is inputted into the common-mode signal absorber, the common-mode signal reflection circuit is for reflecting the common-mode signal within a specific frequency band. Afterward, the reflection of the common-mode signal within the specific frequency band will be absorbed by an impedance element of the impedance-matching network. Thus, the common-mode signal within the specific frequency band may be absorbed by the impedance-matching network so as to avoid to interfere signals transmitted on a communication system.
Abstract: The measuring cup includes numerous embodiments configured for a user to precisely determine the cup contents without need to lift the cup to one's eye level or to lower the eye level to the level of the cup contents. The various embodiments include folding cups; cups having transparent passages in the wall; cups having adjustably positionable bottoms; cups having level indicator rods in the cup interior extending upward from the cup bottom; cups having one or more filaments extending across the cup interior; cups having rigid level indicators spanning the cup interior; cups having adjustably positionable level indicator tabs therein; cups having buoyant level indicator tabs adjustably positionable in the cup interior; and cups having removable clip-on scales extending down along the interior of the cup wall, the scales having a plurality of attachment points for the removable attachment of a level indicator tab at a desired attachment point.
Type:
Grant
Filed:
June 17, 2016
Date of Patent:
February 19, 2019
Assignee:
King Saud University
Inventors:
Mohd Aftab Alam, Fahad Ibrahim Al-Jenoobi, Abdullah M. Al-Mohizea
Abstract: A friction stir welding tool comprising a composite of a tungsten-rhenium alloy and hafnium carbide particles, wherein a crystallite size of the tungsten-rhenium alloy is no more than 100 nm, wherein the hafnium carbide particles are dispersed within the tungsten-rhenium alloy, a method of fabricating the friction stir welding tool, and a method of friction stir welding a metal joint using the tool. Various embodiments of the friction stir welding tool, the method of fabricating the tool, and the method of friction stir welding using the tool are provided.
Type:
Grant
Filed:
July 18, 2018
Date of Patent:
February 19, 2019
Assignee:
King Fahd University of Petroleum and Minerals
Inventors:
Zafar Iqbal, Abdelrahman N. Shuaib, Necar Merah, Nouari Saheb
Abstract: The present disclosure provides methods of using probiotic arginolytic oral compositions including isolated arginolytic bacterial strains to increase arginolytic activity in the oral cavity, increase ammonia-producing bacteria in the oral cavity, and/or to treat and/or prevent oral disorders, such as caries.
Type:
Grant
Filed:
January 27, 2017
Date of Patent:
February 19, 2019
Assignee:
University of Florida Research Foundation, Inc.
Inventors:
Marcelle Matos Nascimento, Robert A. Burne
Abstract: A vanadium oxide catalyst supported on a cerium oxide and zirconium oxide composite core is described. The catalyst comprises 0.1-3 wt % vanadium oxide relative to the total catalyst weight, and the catalyst is in the form of microparticles having diameters of 5-80 ?m. A method using a wetness impregnation technique to produce the catalyst is described. The use of the catalyst in the partial oxidation of methanol to produce formaldehyde is specified, along with the catalyst's stability for reaction periods of 50 or more hours. A method of regenerating the catalyst for multiple reactions is also described.
Type:
Grant
Filed:
October 11, 2017
Date of Patent:
February 19, 2019
Assignee:
King Abdulaziz University
Inventors:
Hitoshi Inokawa, Sharif F. Zaman, Muhammad A. Daous, Abdulrahim Al-Zahrani, Lachezar Petrov
Abstract: The present invention is directed to methods of treating T-ALL that involve administering an inhibitor of jumonji D3 (JMJD3) demethylase. Another embodiment of the invention relates to methods inhibiting T-ALL cell proliferation and/or survival that involves administering an inhibitor of jumonji D3 (JMJD3) demethylase to a population of T-ALL cells.
Abstract: A semiconducting nanocomposite and a dye-sensitized solar cell including the same, wherein the semiconducting nanocomposite comprises nanocomposite particles selected from the group consisting of TiO2/ZnO/CdS, TiO2/ZnO/CdSe, TiO2/ZnO/PbS, TiO2/ZnO/PbSe, TiO2/ZnS/CdSe, TiO2/ZnS/PbS, TiO2/ZnS/PbSe, WO3/ZnO/CdSe, Nb2O5/ZnO/CdSe, and combinations thereof. Various embodiments of each component of the dye-sensitized solar cell, including electrodes, conductive layers, dyes, and electrolytes are also provided.
Type:
Grant
Filed:
December 27, 2017
Date of Patent:
February 19, 2019
Assignees:
Imam Abdulrahman Bin Faisal University, KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS
Inventors:
Jwaher Mohammed Alghamdi, Mohammed Ashraf Gondal
Abstract: An organic light emitting device is described, having an OLED including an anode, a cathode, and at least one organic layer between the anode and cathode. At least a portion of an electrode surface includes a plurality of scattering structures positioned in a partially disordered pattern resembling nodes of a two dimensional lattice. The scattering structures are positioned around the nodes of the two dimensional lattice with the average distance between the position of each scattering structure and a respective node of the lattice is from 0 to 0.5 of the distance between adjacent lattice nodes. A method of manufacturing an organic light emitting device and a method of enhancing the light-extraction efficiency of an organic light emitting device are also described.
Type:
Grant
Filed:
August 4, 2017
Date of Patent:
February 19, 2019
Assignee:
The Regents of the University of Michigan
Abstract: In one aspect, the invention provides an implantable device comprising a uniform mixture of components including degradable polymer, inorganic bone particulate either natural or synthetic, a drug, and a soluble microporagen. In some embodiments, the uniform mixture further includes a soluble polymer macroporagen. In some embodiments, the uniform mixture is coated with an immobilized outer porous layer comprising or consisting of synthetic or natural inorganic bone granules. In further aspects, the invention provides an implantable device comprising a composite core of degradable polymer, bone, and a drug, and a coating comprising or consisting of microporous bone overlayer covering the degradable composite core.
Type:
Grant
Filed:
January 11, 2018
Date of Patent:
February 19, 2019
Assignee:
University of Utah Research Foundation
Inventors:
Amanda Elaine Brooks, David W. Grainger, Kristofer D. Sinclair, Benjamin Delbert Brooks
Abstract: The present invention relates to genetic analysis and evaluation utilizing copy-number variants or polymorphisms. The methods utilize array comparative genomic hybridization and PCR assays to identify the significance of copy number variations in a human or non-human animal subject or subject group.
Type:
Grant
Filed:
May 3, 2007
Date of Patent:
February 19, 2019
Assignees:
Population Bio, Inc., The Research Foundation of the State University of New York
Inventors:
James Chinitz, Eli Hatchwell, Jasmin Roohi
Abstract: ‘NCCO1’ is a new cultivar of smokebush is disclosed, characterized by a compact habit, dark purple foliage, and large, purple inflorescences. The new variety is a Cotinus coggygria, typically produced as an outdoor ornamental plant.