Patents Assigned to University
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Patent number: 12168612Abstract: The present disclosure relates to a strategy to synthesize antimony- and zinc-doped tin oxide particles with tunable band gap characteristics. The methods yield stable and monodispersed particles with great control on uniformity of shape and size. The methods produce undoped and antimony and zinc-doped tin oxide stand-alone and core-shell particles, both nanoparticles and microparticles, as well as antimony and zinc-doped tin oxide shells for coating particles, including plasmonic core particles.Type: GrantFiled: January 31, 2020Date of Patent: December 17, 2024Assignees: University of Houston System, National Central UniversityInventors: T. Randall Lee, Riddhiman Medhi, Sang Ho Lee, Chien-Hung Li, Allan J. Jacobson, Tai-Chou Lee
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Patent number: 12168185Abstract: An amusement park attraction system including a ride vehicle comprising an input device, and a control system configured to determine a parameter value associated with a force imparted on the input device. The parameter value includes a value of the force imparted on the input device, a value of a deformation caused by the force imparted on the input device, or both. The control system is also configured to control movement of the ride vehicle of the amusement park attraction system based on the parameter value.Type: GrantFiled: February 2, 2022Date of Patent: December 17, 2024Assignee: Universal City Studios LLCInventors: Grace Catheryn Haynes, Michelle Smith, John David Smith, Neil Andrew Leiba, Doug Joseph
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Patent number: 12168652Abstract: Disclosed herein are carborane derivatives of Formula I or Formula V, or a pharmaceutically acceptable salt thereof, for use as neuromuscular blocking agents. The carborane is substituted with two cationic functional groups selected from amines that form ammonium cations, ethers and/or alcohols that form oxonium cations, sulfides and/or thiols that form sulfonium cations, and phosphanes and/or phosphines that form phosphonium cations.Type: GrantFiled: March 27, 2019Date of Patent: December 17, 2024Assignee: The Curators of the University of MissouriInventors: George R. Kracke, Lalit N. Goswami, Marion F Hawthorne, Satish S. Jalisatgi
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Patent number: 12167720Abstract: An artificial structure for promoting microalgae growth includes a 3D-printed structure formed by positioning a printing surface on a movable stage of a 3D bioprinter in contact with a bio-ink that includes a mixture of a pre-polymer material with one or more of cellulose-derived nanocrystals (CNC), and microalgae cells. By projecting modulated light onto the printing surface while moving the stage, the bio-ink is progressively polymerized to define layers of an artificial coral structure with microalgae cells disposed thereon, where the artificial coral structure is configured to scatter light within the structure.Type: GrantFiled: August 28, 2020Date of Patent: December 17, 2024Assignee: The Regents of the University of CaliforniaInventors: Shaochen Chen, Dimitri Deheyn, Shangting You, Daniel Wangpraseurt, Silvia Vignolini
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Publication number: 20240408675Abstract: A method for adjusting laser control parameters of a laser additive manufacturing system for construction of a part is provided. The method may include performing a laser scan of a building surface, and detecting spectral and intensity response information indicative of at least a temperature at the building surface. The method may also include correlating the spectral and intensity response information with spatial positioning of the laser during the laser scan to generate spatially-correlated spectral and intensity response information.Type: ApplicationFiled: January 17, 2024Publication date: December 12, 2024Applicant: The Johns Hopkins UniversityInventors: Steven M. Storck, Mary E. Daffron, Vincent R. Pagan, Brendan P. Croom, Ari M. Lax
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Publication number: 20240414035Abstract: A receiver includes a voltage-to-time converter configured to sequentially output a first converted signal and a second converted signal based on a first signal, a second signal, and a time difference; a first time comparator configured to determine a first bit value based on a first first-arrival signal (FAS) and output first data including the first bit value; a delay time generator configured to select a non-target signal and a target signal based on the first bit value and from among the first converted signal and the second converted signal; and a second time comparator configured to determine a second bit value based on a second FAS and output second data including the second bit value.Type: ApplicationFiled: December 6, 2023Publication date: December 12, 2024Applicants: SAMSUNG ELECTRONICS CO., LTD., Nanyang Technological UniversityInventors: Jueon Kim, Taehyoung Kim, Donghyun Yoon, Myoungbo Kwak, Jaewoo Park, Youngdon Choi, Junghwan Choi
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Publication number: 20240409633Abstract: Provided herein, in one aspect, is a method of preventing or delaying the onset of clinical type 1 diabetes (T1D), comprising: providing a non-diabetic subject who is at risk for T1D; administering a prophylactically effective amount of an anti-CD3 antibody to the non-diabetic subject; and determining, prior to or after the administering step, that the non-diabetic subject has more than about 5% to more than about 10% TIGIT+KLRG1+CD8+ T-cells in all CD3+ T-cells, which is indicative of successful prevention or delay of the onset of clinical T1D.Type: ApplicationFiled: May 16, 2024Publication date: December 12, 2024Applicants: Provention Bio, Inc., Benaroya Research Institute at Virginia Mason, Yale UniversityInventors: Francisco LEON, Kevan C. HEROLD, Sarah Alice LONG, Peter S. Linsley
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Publication number: 20240415003Abstract: A compound comprising a first ligand LA of Formula I, is provided. In Formula I, moiety A is a monocyclic ring or a polycyclic fused ring system, moiety B is a polycyclic fused ring system; each of Z1 to Z4 is C or N; each of K1 and K2 is a direct bond or a linker; at least one RB or RA comprises, where T is B, C, N, Si, Ge, Bi, or P; V is a direct bond or a linker; R1 and R2 are present, and R3 is optionally present; each substituent is independently hydrogen or a General Substituent defined herein; and at least two of R1, R2, and R3 has two or more carbon atoms. Formulations, OLEDs, and consumer products containing the compound are also provided.Type: ApplicationFiled: May 8, 2024Publication date: December 12, 2024Applicant: Universal Display CorporationInventors: Alexey Borisovich DYATKIN, Wei-Chun SHIH
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Publication number: 20240409613Abstract: An azide-containing cross-linker and method of preparing the same are provided. Such cross-linker can be used as an intermediate in a scalable production of a cross-linked hemoglobin protein having its beta subunits covalently linked to the azide-containing cross-linker. The present disclosure also pertains to a hemoglobin-based oxygen carrier (HBOC) comprising a pair of azide cross-linked hemoglobin proteins coupled by a copper (I) catalyzed azide-alkyne cycloaddition (CuAAC) and a method for preparing the same. The HBOC may be used in a method for increasing oxygen transport or for use in transfusions or perfusions.Type: ApplicationFiled: June 7, 2024Publication date: December 12, 2024Applicant: The Governing Council of the University of TorontoInventors: Nathan WU, Ronald KLUGER
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Publication number: 20240407712Abstract: Embodiments pertain to a computer-implemented method of predicting muscle fatigue in a subject by: (1) receiving data related to muscle fatigue in a muscle of the subject; (2) feeding the data into an algorithm to predict the muscle fatigue; and (3) outputting the predicted muscle fatigue. The algorithm my include: (a) an active compartment (M_A) model representing individual motor units (MUs) generating force at full capacity, (b) a resting compartment (M_R) model representing inactive MUs capable of rapid activation into force production, (c) a centrally fatigued compartment (M_FC) model representing fatigued MUs due to a central mechanism dominant at zero or near-zero joint velocities, with rapid recovery, and (d) a peripherally fatigued compartment (M_FP) model representing fatigued MUs due to a peripheral mechanism dominant at higher velocities, with slow recovery. Further embodiments pertain to a computing device for predicting muscle fatigue in a subject in accordance with such methods.Type: ApplicationFiled: June 12, 2024Publication date: December 12, 2024Applicant: Texas Tech University SystemInventors: James Yang, Ritwik Rakshit
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Publication number: 20240410808Abstract: A core holder assembly (100) for holding a test sample (200) including a consolidated porous medium includes an outer barrel including a central passage defined by an inner surface, a confining solid positioned in the central passage of the outer barrel, wherein the confining solid includes an outer surface sealed against the inner surface of the outer barrel and an inner surface, wherein the confining solid includes a rigid, lead-free material, and the test sample positioned within the confining solid, wherein the inner surface of the confining solid is sealed against an outer surface of the test sample.Type: ApplicationFiled: October 12, 2022Publication date: December 12, 2024Applicant: William Marsh Rice UniversityInventors: Sibani L. Biswal, George J. Hirasaki, Eric D. Vavra, Maura C. Puerto, Khalid Mateen, Kun Ma
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Publication number: 20240408133Abstract: A medicinal nanocomposite is provided. The medicinal nanocomposite includes 80 to 99 wt. % carrier particles of a porous silicate material selected from a group including mesoporous silica, silicalite, mesosilicalite, silver-incorporated silicalite, and silver-incorporated mesosilicalite, the carrier particles comprising a pore framework, 0.5 to 10 wt. % silver nanoparticles (Ag NPs) disposed the pore framework, and 0.5 to 10 wt. % of a platinum-containing pharmaceutical compound disposed on at least one surface selected from an interior pore surface of the carrier particles, an exterior surface of the carrier particles, and a surface of the silver nanoparticles. The medicinal nanocomposite releases less than 10 mole % of the platinum-containing pharmaceutical compound after 60 to 84 hours at a pH of 4.5 to 7, based on an initial amount of the platinum-containing pharmaceutical compound present in the medicinal nanocomposite. .Type: ApplicationFiled: August 21, 2024Publication date: December 12, 2024Applicant: Imam Abdulrahman Bin Faisal UniversityInventors: B. Rabindran JERMY, Vijaya RAVINAYAGAM, Suriya REHMAN
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Publication number: 20240409902Abstract: Among the various aspects of the present disclosure is the provision of systems and methods for growing or culturing podocytes and uses thereof. In one aspect, a podocyte culture system including an ECM-patterned substrate is disclosed. The ECM-patterned substrate includes a compliant substrate. The compliant substrate includes a predetermined stiffness ranging from about 0.1 kPa to about 10 kPa. The ECM-patterned substrate further includes a plurality of patterned elements deposited over an exposed surface of the compliant substrate.Type: ApplicationFiled: October 31, 2022Publication date: December 12, 2024Applicant: Washington UniversityInventors: Hani Suleiman, Guy Genin, Jeffrey Miner, Shumeng Jiang, Chengqing Qu
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Publication number: 20240407333Abstract: An adjustable grooming structure is disclosed, which relates to the field of pet grooming. The adjustable grooming structure includes a shell and a plurality of grooming units installed on the shell for grooming a pet and collecting pet hair, the shell is provided with a pathway for the pet to pass through, and an adjustment unit is arranged on the shell to allow movement of the grooming units towards or away from a center of the pathway. The grooming structure allows the adjustment of the size of the pathway through which a pet passes and can achieve effective grooming.Type: ApplicationFiled: October 17, 2022Publication date: December 12, 2024Applicant: Shenzhen Jumao Universe Technology Co., LtdInventor: Youren TIAN
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Publication number: 20240415004Abstract: A compound comprising a first ligand LA of Formula I, is provided, where: each of moiety A and moiety B is a monocyclic ring or a polycyclic fused ring system; each of X1 to X4 and Z1 and Z2 is C or N; K1 and K2 are each a direct bond or a linker; L1 is a direct bond or an organic linker; each R?, R?, RA and RB is hydrogen or a General Substituent defined herein; and at least one RA or one RB comprises R*, where R* is an alkyl group, a silyl group, a germyl group, or a combination thereof. Formulations, OLEDs, and consumer products containing the compound are also provided.Type: ApplicationFiled: May 8, 2024Publication date: December 12, 2024Applicant: Universal Display CorporationInventors: Zhiqiang JI, Alexey Borisovich DYATKIN, Derek Ian WOZNIAK, Pierre-Luc T. BOUDREAULT, Henry Carl HERBOL
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Publication number: 20240412356Abstract: The present invention relates generally to machine learning and artificial intelligence methods of cell anomaly detection. More specifically, the present invention relates to targeting intracellular anomalies via microscopy-based high-content phenotypic screening and generative neural networks for combinatorial drug screening. As can be seen from the provided description, the claimed invention represents the system and method of cell anomaly detection, which increase reliability of cell anomaly detection. More specifically, the claimed invention provides an assessment of cell inter-component (inter-organelle) organization for detecting cell anomaly.Type: ApplicationFiled: October 30, 2022Publication date: December 12, 2024Applicant: B.G. Negev Technologies & Applications Ltd., at Ben-Gurion UniversityInventors: Assaf ZARITSKY, Naor KOLET
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Publication number: 20240413142Abstract: Disclosed is a Light-Emitting Device-Thin Film Transistor (LED-TFT) integration structure, comprising a substrate comprising a light emitting area and a driving area; a metal reflective film formed on the substrate; a buffer layer formed on the metal reflective film; LED disposed in the light emitting area; a protective layer formed on the LED; a thin film transistor disposed in the driving area and configured to drive the LED; and an ohmic contact metal for electrically connecting a cathode of the LED with the metal reflective film, wherein the LED and the thin film transistor are integrally formed on the substrate.Type: ApplicationFiled: October 13, 2022Publication date: December 12, 2024Applicant: Korea University Research and Business FoundationInventor: In Hwan LEE
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Publication number: 20240409921Abstract: Methods and systems for characterizing the spatial genomic organization and gene expression in single cells is described. The methods described herein is used to generate spatial and transcriptomic libraries to determine the three-dimensional organization associated with the expression of nucleic acids. Implementations described herein can be used for research or diagnostic purposes.Type: ApplicationFiled: June 4, 2024Publication date: December 12, 2024Applicant: University of WashingtonInventor: Zhi-jun Duan
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Publication number: 20240408050Abstract: Compositions including dihydromyricetin (DHM) and methods for forming them through spray drying.Type: ApplicationFiled: August 22, 2024Publication date: December 12, 2024Applicants: The Trustees of Princeton University, Cheers Health, Inc.Inventors: Robert K. PRUD'HOMME, Brooks POWELL, Vikram PANSARE, Nicholas CAGGIANO, Jie FENG
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Publication number: 20240407373Abstract: The present disclosure provides a phage for lysing Burkholderia gladioli and use thereof, and belongs to the technical field of phages. The phage for lysing Burkholderia gladioli provided by the present disclosure is Burkholderia gladioli phage vB_BglM_WTB with an accession number of CCTCC M 2023525, which is a novel phage. The phage provided by the present disclosure has a strong lytic effect on the Burkholderia gladioli with higher temperature tolerance and wider acid-base tolerance range and effectively kills the Burkholderia gladioli on food surface, providing a new strategy for controlling the Burkholderia gladioli in food processing and environment.Type: ApplicationFiled: October 10, 2023Publication date: December 12, 2024Applicant: Hefei University of TechnologyInventors: Yingwang YE, Ting WANG, Na LING, Bin CHENG, Rui JIAO, Xiyan ZHANG, Danfeng ZHANG