Abstract: A soft-landing (SL) instrument for depositing ions onto substrates using a laser ablation source is described herein. The instrument of the instant invention is designed with a custom drift tube and a split-ring ion optic for the isolation of selected ions and is capable of operating at atmospheric pressure. The drift tube allows for the separation and thermalization of ions formed after laser ablation through collisions with an inert bath gas that allow the ions to be landed at energies below 1 eV onto substrates. The split-ring ion optic is capable of directing ions toward the detector or a landing substrate for selected components.
Type:
Grant
Filed:
August 25, 2017
Date of Patent:
December 29, 2020
Assignee:
University of North Texas
Inventors:
Guido Fridolin Verbeck, IV, Stephen Davila
Abstract: Devices of the present disclosure may macerate and extract debris from inside a lumen. Such devices may include an extraction core, a tube including a side wall and a window in the side wall, and a rotatable helical formation disposed inside the tube. In some embodiments, the rotatable helical formation has a variable pitch.
Type:
Grant
Filed:
March 27, 2018
Date of Patent:
December 29, 2020
Assignee:
National University of Ireland, Galway
Inventors:
Mark Bruzzi, Saeid Kasiri Ghahi, Paul Heneghan
Abstract: A radiation detection system may include a mobile device having a flash memory. The device may monitor various characteristics of the flash memory to determine when damage to the flash memory has occurred from radiation exposure. The device may associate damage to the flash memory with a radiation dose, and determine a level of radiation to which the memory, and thus the device, has been exposed. The device also may determine a length of time and locations where the radiation exposure has occurred. If the device determines that the level of radiation exposure exceeds a threshold associated with a safe level of radiation exposure for a human user, the device may generate an alert to the user.
Type:
Grant
Filed:
May 17, 2019
Date of Patent:
December 29, 2020
Assignee:
Board of Trustees of the University of Alabama, for and on behalf of the University of Alabama in Huntsville
Abstract: Methods for making porous materials having metal alloy nanoparticles formed therein are described herein. By preparing a porous material and delivering the precursor solutions under vacuum, the metal precursors can be uniformly embedded within the pores of the porous material. Once absorption is complete, the porous material can be heated in the presence of one or more functional gases to reduce the metal precursors to metal alloy nanoparticles, and embed the metal alloy nanoparticles inside of the pores. As such, the metal alloy nanoparticles can be formed within the pores, while avoiding surface wetting and absorption problems which can occur with small pores.
Type:
Grant
Filed:
September 24, 2018
Date of Patent:
December 29, 2020
Assignees:
Toyota Motor Engineering & Manufacturing North America, Inc., Toyota Jidosha Kabushiki Kaisha, The University of Akron
Inventors:
Li Qin Zhou, Kan Huang, Tomoyuki Nagai, Hongfei Jia, Hisao Kato, Xiaochen Shen, Zhenmeng Peng
Abstract: In embodiments described herein, a light emitting diode device comprises an emission device with an emission region and a bottom contact layer. The emission region comprises n cascading emission layers, where n is a whole and positive number. The n cascading emission layers comprise at least one superlattice structure. In an embodiment, a tunnel junction is spaced between a first superlattice structure and a second superlattice structure. In an embodiment, light extraction is enhanced with a trapezoidal shaped chip, a roughened exit interface, and encapsulation of the chip with a hemispherical shaped polymer. In an embodiment, the superlattice structure may be repeated periods of InAs/AlGaInSb. In another embodiment, the superlattice may be repeated periods of InAs/GaInSb/InAs/AlAsSb. In another embodiment, between the bottom contact layer and the emission region is a tunnel junction where the bottom contact layer and the tunnel junction form an n-type anode layer.
Type:
Grant
Filed:
July 8, 2019
Date of Patent:
December 29, 2020
Assignee:
University of Iowa Research Foundation
Inventors:
Aaron Muhowski, Cassandra Bogh, John Prineas, Jon Olesberg
Abstract: Metal (II) phosphate powders, lithium metal phosphate powders for a Li-ion battery and methods for manufacturing the same are provided. The lithium metal phosphate powders are represented by the following formula (II): LiFe1-aMaPO4??(II) wherein M comprises at least one metal selected from the group consisting of Mn, Co, Ni, Cu, Cr, V, Mo, Ti, Zn, Zr, Tc, Ru, Rh, Pd, Ag, Cd, Pt, Au, Al, Ga, In, Be, Mg, Ca, Sr, B and Nb, 0.5<a?1, the lithium metal phosphate powders are composed of plural flake powders, and a length of each of the flake powders is ranged from 50 nm to 10 ?m.
Abstract: An image guide comprising glass or plastic planar substrate, a first hologram area, a second hologram area, and a third hologram area which are formed on the substrate as surface relief grating, period and direction of diffraction structure of the first, second, and third hologram areas have a relationship which is a sum of grating vectors of the first, second, and third hologram areas becomes zero, depth of diffraction structure on the first hologram area is a uniform in the own hologram area, and depth of diffraction structure on the second or third hologram area is chirped in the own hologram area increases luminance and uniformity of virtual image.
Type:
Grant
Filed:
February 15, 2018
Date of Patent:
December 29, 2020
Assignees:
HITACHI, LTD., Arizona Board of Regents on Behalf of the University Of Arizona
Abstract: Described are metal organochalcognides which are bulk nanomaterials, expressing monolayer properties in their as-synthesized states. Also described are certain novel metal organochalcogenide compositions. Further described are several methods of preparation of metal organochaleogenides, both solution- and vapor deposition-based, and methods of use of the resulting metal chalcogenides in assays and devices.
Type:
Grant
Filed:
August 4, 2017
Date of Patent:
December 29, 2020
Assignee:
The Regents of the University of California
Inventors:
James Nathan Hohman, Mary S. Collins, Tess E. Smidt
Abstract: A process for the facile prelithiation of silicon-containing materials for use in lithium ion batteries is disclosed. The process can include using a lithium additive comprising LiSt, Li2O—SiO2—TiO2—P2O5, LATP, LAGP, LLTO, LLZO, Li3N, LiBF4, Li2CO3, Li3PO4, lithium-enriched variations thereof, or combinations thereof. The resulting prelithiated materials demonstrate enhanced physicochemical properties providing for high target capacity and excellent cycle stability for the batteries prepared with the materials.
Type:
Grant
Filed:
March 20, 2018
Date of Patent:
December 29, 2020
Assignee:
North Carolina Agricultural and Technical State University
Abstract: The present disclosure relates to a method for storage or transportation of graphene oxide. The method for storage or transportation of graphene oxide comprises the steps of: carrying out wet spinning of a graphene oxide spinning solution to a coagulating bath to obtain graphene oxide pellets; drying the obtained graphene oxide pellets; storing or transporting the dried graphene oxide pellets; and redispersing the stored or transported graphene oxide pellets.
Abstract: This invention is related to use of exosomes for biomarker analysis for early detecting and characterizing of disease progression of cancer. Further, the invention provides bioengineered exosomes for use in methods of targeting and treating cancer.
Type:
Grant
Filed:
October 19, 2017
Date of Patent:
December 29, 2020
Assignees:
Northwestern University, Case Western Reserve University
Inventors:
Huiping Liu, Erika K. Ramos, Nurmaa K. Dashzeveg, Golam Kibria
Abstract: A phase singularity identification system includes: a signal reception unit for receiving a single activity electrogram signal measured through a single-electrode catheter at a particular point of a cardiac muscle cell; a phase calculation unit for calculating a phase from the received single activity electrogram signal; and a phase singularity identification unit for identifying through the calculated phase if the particular point of the cardiac muscle cell is a phase singularity. Accordingly, it is possible to identify the phase singularity of a rotor by using a single-electrode catheter rather than a multi-electrode catheter, thereby significantly reducing time required and costs spent in comparison with prior art, and it is possible to accurately identify the phase singularity of the rotor, thus the system can be used for a radiofrequency electrode catheter ablation procedure for cardiac arrhythmia treatment.
Type:
Grant
Filed:
February 22, 2017
Date of Patent:
December 29, 2020
Assignee:
INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY
Abstract: A treatment of Alzheimer's disease and other disorders involving protein misfolding or aggregation is provided by enhancing or sustaining an antibody response against predominantly directed against pathological protein aggregates or neo-epitopes present on pathogenic forms of said protein or protein complex. Furthermore, therapeutic methods are described, wherein ex vivo stimulated antigen-selected peripheral blood lymphocytes are regrafted into the cognate donor.
Type:
Grant
Filed:
December 18, 2017
Date of Patent:
December 29, 2020
Assignee:
New York University
Inventors:
Karsten Henco, Roger Nitsch, Jan Grimm, Anja Zeller, Marcel Maier
Abstract: A double-stranded nucleic acid molecule includes a first polynucleotide chain including a base sequence represented by Chemical Formula (1) (SEQ ID NO:1) and a second polynucleotide chain including a base sequence complementary to the first polynucleotide chain. A method for preventing and/or treating a tumor includes a step in which the double-stranded nucleic acid molecule is administered to a test subject.
Abstract: A remote SERS spectrum detection system and a method thereof. The system includes: a pulsed laser light source, configured to emit Raman excitation light; an optical fiber Raman coupling module, configured to couple the Raman excitation light; the optical fiber Raman probe, configured to transmit the Raman excitation light to an object to be measured to generate a SERS signal light, a backscattered SERS signal light being coupled to a monochromator through the optical fiber Raman coupling module; the monochromator, configured to split the backscattered SERS signal light, to obtain backscattered SERS signal lights at different wavelengths; a high-speed photodetector, configured to convert the backscattered SERS signal lights into time-resolved electrical signals; a processor, for analyzing electrical signals, retrieving a SERS spectrum of the remote object to be measured, and controlling automatic scanning of a grating in the monochromator to achieve clock synchronization.
Abstract: Disclosed herein are a chromium compound represented by Formula 1a or 1c and a catalyst system including the same, exhibiting superior catalytic activity in an olefin trimerization reaction: [{CH3(CH2)3CH(CH2CH3)CO2}2Cr(OH)]??[Formula 1a] [{CH3(CH2)3CH(CH2CH3)CO2}2Cr(OH)]4.2H2O.
Type:
Grant
Filed:
August 22, 2019
Date of Patent:
December 29, 2020
Assignees:
AJOU UNIVERSITY INDUSTRY—ACADEMIC COOPERATION
FOUNDATION, S-PRECIOUS CATALYSTS INC.
Inventors:
Bun Yeoul Lee, Jong Yeob Jeon, Dong Sik Park
Abstract: Disclosed are nanoparticles for the delivery of a therapeutic agent or a diagnostic agent to a subject that include a chitosan and a polyphosphate, wherein the chitosan nanoparticles are coated with polylactic acid. Methods of delivering a therapeutic agent or a diagnostic agent to a subject for the treatment or prevention of a disease are also disclosed. For example, the treatment of ovarian cancer in a subject by inhibiting the expression of ZNF034 is disclosed.
Type:
Grant
Filed:
June 23, 2016
Date of Patent:
December 29, 2020
Assignee:
Board of Regents, The University of Texas System
Inventors:
Burcu Aslan, Gabriel Lopez-Berestein, Anil K. Sood
Abstract: Provided, inter alia, are methods for treating an epilepsy disorder using a 5HT receptor agonist, or a pharmaceutically acceptable salt thereof.
Type:
Grant
Filed:
February 24, 2016
Date of Patent:
December 29, 2020
Assignee:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Abstract: Electrochemical devices, and associated materials and methods, are generally described. In some embodiments, an electrochemical device comprises an electroactive material. The electroactive material may comprise an alloy having a solid phase and a liquid phase that co-exist with each other. As a result, such a composite electrode may have, in some cases, the mechanical softness to permit both high energy densities and an improved current density as compared to, for example, a substantially pure metal electrode.
Type:
Application
Filed:
April 17, 2020
Publication date:
December 24, 2020
Applicants:
Massachusetts Institute of Technology, Carnegie Mellon University
Inventors:
Yet-Ming Chiang, Richard Park, Venkatasubramanian Viswanathan, Shashank Sripad, Zijian Hong, Pinwen Guan