Patents Assigned to University
  • Oxide semiconductor device and method for manufacturing same
    Patent number: 10896978
    Abstract: In an oxide semiconductor device including an active layer region constituted by an oxide semiconductor, stability when a stress is applied is improved. The oxide semiconductor device includes an active layer region constituted by an oxide semiconductor of indium (In), gallium (Ga), and zinc (Zn), wherein the active layer region contains an element selected from titanium (Ti), zirconium (Zr), and hafnium (Hf) that are Group 4 elements, or carbon (C), silicon (Si), germanium (Ge), and tin (Sn) that are Group 14 elements at a number density in a range of 1×1016 to 1×1020 cm?3.
    Type: Grant
    Filed: September 4, 2017
    Date of Patent: January 19, 2021
    Assignees: V TECHNOLOGY CO., LTD., TOHOKU UNIVERSITY
    Inventors: Tetsuya Goto, Michinobu Mizumura
  • Hybrid nanoparticles containing boron-doped graphene quantum dots and applications thereof
    Patent number: 10894020
    Abstract: Provided is a hybrid nanoparticle, including an aggregate assembled from a plurality of polymeric molecules, and a plurality of boron-doped graphene quantum dots localized in the aggregate. The polymeric molecule is preferably a pH-responsive dendrimer; the polymeric molecule and the boron-doped graphene quantum dot may be separately associated with different drugs; and hybrid nanoparticle may further include a targeting molecule, such as a rabies virus glycoprotein. Also provided is a method of controlling disassembly of a hybrid nanoparticle, including applying a high-frequency magnetic field to the hybrid nanoparticle to induce disassembly thereof. Also provided is an application of the hybrid nanoparticle for preparing a tumor-penetrating drug carrier.
    Type: Grant
    Filed: January 4, 2019
    Date of Patent: January 19, 2021
    Assignee: NATIONAL TSING HUA UNIVERSITY
    Inventors: Shang-Hsiu Hu, Yu-Lin Su
  • Production of carboxylated nanocelluloses
    Patent number: 10894838
    Abstract: The present disclosure provides methods for producing carboxylated nanocelluloses. Compared with conventional methods, the methods of the present disclosure are simple and cost-effective in the production of carboxylated (or carboxy) nanocelluloses, in embodiments nanofibers and/or nanowhiskers, directly from raw biomass, including lignocellulose wood, non-wood sources, non-lignocellulose wood, lignocellulose or pure cellulose. The carboxy groups on the surface of nanocellulose thus produced can then be easily modified into functional derivatives such as amide, acetate, ether, ester, etc. The resulting nanocelluloses may be used to form purifying agents and/or filters to remove impurities from wastewater.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: January 19, 2021
    Assignee: The Research Foundation for the State University of New York
    Inventors: Benjamin S. Hsiao, Benjamin Chu, Priyanka R. Sharma
  • Small molecule dye for molecular imaging and photothermal therapy
    Patent number: 10894121
    Abstract: Disclosed is a small molecule dye for use in imaging in the near-infrared window, namely between 1000 nm-1700 nm wavelength. The present dyes are also useful for photoacoustic imaging and photothermal therapy. The dyes have a structure of a D-A-D (donor-acceptor-donor) fluorescent compound core and side chains rendering the compounds water soluble and easily conjugated to hydrophilic polymers and/or targeting ligands. Further disclosed is compound, CH1055 that can be PEGylated, conjugated to a targeting ligand, or conjugated to taurine. Key steps utilized to assemble the core structure of the target included a cross-Suzuki coupling reaction, iron reduction and N-thionylaniline induced ring closure. Four carboxylic acid groups were introduced into the donor-acceptor-donor (D-A-D) type fluorescent compound to impart a certain aqueous solubility and to allow facile conjugation to targeting ligands.
    Type: Grant
    Filed: November 12, 2018
    Date of Patent: January 19, 2021
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Zhen Cheng, Xuechuan Hong, Hongjie Dai, Hao Chen, Alexander Antaris, Kai Cheng
  • Stacking fault-free semipolar and nonpolar GaN grown on foreign substrates by eliminating the nitrogen polar facets during the growth
    Patent number: 10896818
    Abstract: Methods and structures for forming epitaxial layers of Ill-nitride materials on patterned foreign substrates with low stacking fault densities are described. Semipolar and nonpolar orientations of GaN that are essentially free from stacking faults may be grown from crystal-growth facets of a patterned substrate. Etching can be used to remove stacking faults if present. Crystal growth with an impurity can eliminate crystal growth from a facet that is responsible for stacking fault formation and permit substantially stacking-fault-free growth of the Ill-nitride material.
    Type: Grant
    Filed: August 11, 2017
    Date of Patent: January 19, 2021
    Assignee: Yale University
    Inventors: Jung Han, Jie Song
  • Fabricated self-resilient energy-dissipation double-steel-plate slotted shear wall structure
    Patent number: 10895087
    Abstract: A fabricated self-resilient energy-dissipation double-steel-plate slotted shear wall structure includes steel columns, H-shaped steel beams and a shear wall assembly. The shear wall assembly includes left and right groups of slotted wall plates and is connected with flanges of the H-shaped steel beams through angle steel. Connecting ring plate assemblies are fixed to upper and lower ends of each steel column and each comprise an outer ring plate, an inner ring plate and a short side plate. A long side plate is fixedly arranged on each steel column tube and is connected with one slotted wall plate through a plurality of self-locking hasps. A plurality of pre-stressed steel strands are arranged on two sides of each long side plate.
    Type: Grant
    Filed: July 5, 2018
    Date of Patent: January 19, 2021
    Assignee: QINGDAO UNIVERSITY OF TECHNOLOGY
    Inventors: Ben Mou, Xi Li, Jijun Miao
  • Optical device and method for modifying the refractive index of an optical material
    Patent number: 10893936
    Abstract: An optical device comprising an optical hydrogel with select regions that have been irradiated with laser light having a pulse energy from 0.01 nJ to 50 nJ and a wavelength from 600 nm to 900 nm. The irradiated regions are characterized by a positive change in refractive index of from 0.01 to 0.06, and exhibit little or no scattering loss. The optical hydrogel is prepared with a hydrophilic monomer.
    Type: Grant
    Filed: April 19, 2019
    Date of Patent: January 19, 2021
    Assignee: University of Rochester
    Inventors: Wayne H. Knox, Li Ding, Jay F. Kunzler, Dharmendra Jani
  • Enhanced depletion of targeted cells with CD47 blockade and an immune costimulatory agonist
    Patent number: 10894831
    Abstract: Methods are provided for targeting cells for depletion, including without limitation tumor cells, in a regimen comprising contacting the targeted cells with a combination of agents that modulate immunoregulatory signaling. Immunoregulatory modulating agents include (i) an agent that blockades CD47 activity; and (ii) an agent that agonizes an immune costimulatory molecule, e.g. CD137. The regimen may further comprise an agent that specifically binds to the target cell, e.g. an antibody or biologically active fragment or derivative thereof. The level of depletion of the targeted cell is enhanced relative to a regimen in which a single immunoregulatory modulating agent is used; and the effect may be synergistic relative to a regimen in which a single immunoregulatory modulating agent is used.
    Type: Grant
    Filed: August 26, 2016
    Date of Patent: January 19, 2021
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Peter Schnorr, Akanksha Chhabra, Judith A. Shizuru, Irving L. Weissman, Kipp Andrew Weiskopf
  • System and method of monitoring respiratory parameters
    Patent number: 10893825
    Abstract: A spirometer includes a housing, a mouthpiece coupled to the housing, and a measurement unit. The measurement unit is configured to receive air expelled by a user, and generate an electrical quantity corresponding to a peak expiratory flow or a forced expiratory volume based on the expelled air. The spirometer also includes a processing module supported by the housing, and configured to receive the electrical quantity from the measurement unit, a display coupled to the measurement unit to display an indication of the peak expiratory flow or the forced expiratory volume, and an energy harvester. The energy harvester is coupled to the measurement unit and the processing module, and is configured to receive energy from one of a group consisting of the measurement unit and an energy sensor, store the received energy in an energy storage device, and transfer the energy to the processing module.
    Type: Grant
    Filed: January 31, 2015
    Date of Patent: January 19, 2021
    Assignee: North Carolina State University
    Inventors: James P. Dieffenderfer, Mike A. Brown, Leigh M. Johnson, John F. Muth
  • Systems and methods for control system security
    Patent number: 10896261
    Abstract: A resilient security agent determines a cyber and/or physical health of a control system by, inter alia, communicating cyber-physical key data through cyber-physical control paths of the system, and determining error introduced by the communication. The resilient security agent may be further configured to verify the integrity of acquired cyber-physical state information. The cyber health of the control system may be evaluated by comparing the acquired cyber state information to one or more cyber state profiles. The physical health of the control system may be evaluated by comparing the acquired physical state information to one or more physical state profiles.
    Type: Grant
    Filed: November 29, 2018
    Date of Patent: January 19, 2021
    Assignees: BATTELLE ENERGY ALLIANCE, LLC, VIRGINIA COMMONWEALTH UNIVERSITY
    Inventors: Craig G. Rieger, Timothy R. McJunkin, Milos Manic, Kasun Amarasinghe
  • Peptide inhibitors of calcium channels
    Patent number: 10894811
    Abstract: The present invention relates to fragments of SPLUNC1 protein that bind to calcium channels and inhibit calcium influx into airway smooth muscle and other cells. The invention further relates to methods for regulating calcium influx and treating or preventing disorders responsive to modulating calcium influx through calcium channels.
    Type: Grant
    Filed: February 22, 2017
    Date of Patent: January 19, 2021
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Robert Tarran, Tongde Wu
  • Method of coating a membrane with a catalyst
    Patent number: 10897048
    Abstract: A method of coating a membrane having a first side and an opposite second side and carried with its second side adhering to a backer film is provided. The method includes coating the first side of the membrane with a catalyst ink or slurry with the second side adhering to the backer film and curing the coating on the first side. The backer film is then removed to expose the second side of the membrane which is fed onto a vacuum conveyor with the coated first side facing the conveyor. The second side of the membrane is then coated with a catalyst ink or slurry and the coating on the second side cured after which the membrane is removed from the vacuum conveyor.
    Type: Grant
    Filed: October 18, 2017
    Date of Patent: January 19, 2021
    Assignee: University of Cape Town
    Inventors: Duarte Rui Sousa, Nabeel Hussain
  • Methods for improving proliferation and stemness of limbal stem cells
    Patent number: 10894945
    Abstract: Provided are methods for improving the proliferation and stemness of limbal stem cells (LSCs) by adding a Wnt inhibitor to a medium for limbal explant cultures. When human limbal explants are cultured according to the methods, Wnt/?-catenin signaling is inhibited, resulting in improvement of LSC proliferation, and improvement in the stemness of LSCs, and thus the LSCs may be obtained in high yield.
    Type: Grant
    Filed: March 20, 2017
    Date of Patent: January 19, 2021
    Assignee: CATHOLIC UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION
    Inventors: So-Hyang Chung, Hyun Jung Lee
  • Method and system for performing assessment of spatial ability of a user
    Patent number: 10895952
    Abstract: A method to be implemented by a processor includes steps of: generating an assessment interface which includes a projection graphic that depicts a projection of an expected virtual object onto a plane; controlling a display to display the assessment interface thus generated; controlling, after receiving a movement instruction or a rotation instruction, the display to refresh display of the assessment interface such that a selected one of building block(s) is moved or rotated; and controlling, when it is determined that an asserted virtual object formed by an arrangement of the building block(s) shown in the assessment interface conforms with the expected virtual object, the display to display a result of the assessment.
    Type: Grant
    Filed: June 20, 2018
    Date of Patent: January 19, 2021
    Assignee: NATIONAL TAIWAN NORMAL UNIVERSITY
    Inventors: Jon-Chao Hong, Kai-Hsin Tai, Chi-Ruei Tsai
  • Prosthetic implantable antibacterial surgical mesh
    Patent number: 10894113
    Abstract: The disclosed invention is directed to an implantable surgical prosthetic mesh having a nanofiber comprising one or more antibiotic and a polysaccharide, and a non-polysaccharide polymer deposited on the mesh. The mesh of the invention is shown to be effective in eliminating or minimizing the bacterial population in the mesh and surrounding tissue for at least 14 days from surgical implantation of the mesh.
    Type: Grant
    Filed: April 28, 2020
    Date of Patent: January 19, 2021
    Assignee: King Abdulaziz University
    Inventors: Abdulmalik Mohammed Saleh Altaf, Seham Alsayed Abdulhady, Faissal Abdel-Hady, Mahmoud Abdul Megead Yassien
  • Water level and well depth measuring device
    Patent number: 10895146
    Abstract: A water level and well depth measuring device includes a measuring probe, a control switch, a processing unit, an external power source, and a housing. The measuring probe is inserted into a well to determine a depth to a water level and a depth to a well bottom. An insulated cable, which connects the measuring probe and the housing, is used to lower the measuring probe into the well. The control switch, preferably a three-way switch, the processing unit, and the external power source are integrated into the housing. The control switch may be used to alternate between a level-measuring module and a base-measuring module of the measuring probe. The measuring probe is communicably coupled with the processing unit. Therefore, when the level-measuring module detects a water level and when the base-measuring module is at a well bottom, the processing unit activates a visual indicator and an audible alarm.
    Type: Grant
    Filed: August 6, 2020
    Date of Patent: January 19, 2021
    Assignee: King Abdulaziz University
    Inventor: Mohamed Ahmed Ahmed Rashed
  • Movable belt breakage prevention and catching system for belt conveyor
    Patent number: 10894670
    Abstract: A movable belt breakage prevention and catching system for a belt conveyor includes a detection device, two tracks, a plurality of catching devices, and a control system. The detection device is mounted on the belt conveyor, and is configured to detect whether a belt of the belt conveyor has a crack. The two tracks are symmetrically arranged on both sides of the belt conveyor, and the plurality of catching devices are symmetrically arranged on the two tracks. The control system is configured to control the plurality of catching devices to simultaneously catch the belt firmly when the detection device detects that the belt has a crack; and after firmly catching the belt, each catching device is able to unidirectionally move along with the belt along the track where the catching device is positioned.
    Type: Grant
    Filed: September 21, 2018
    Date of Patent: January 19, 2021
    Assignees: CHINA UNIVERSITY OF MINING AND TECHNOLOGY, XUZHOU ZHIRUN MINING EQUIPMENT SCIENCE AND TECHNOLOGY CO., LTD, INNER MONGOLIA UNIVERSITY OF TECHNOLOGY
    Inventors: Gongbo Zhou, Zhencai Zhu, Ying Wang, Yuan Sun, Ping Zhou, Chaoquan Tang, Gang Shen, Wei Li, Guohua Cao, Yuxing Peng, Xiang Li, Xin Zhang
  • Method and apparatus for accurate parametric mapping
    Patent number: 10895621
    Abstract: Systems and methods are disclosed for a simultaneous 3D T1 and B1+ mapping technique based on VFA imaging using a reference region VFA (RR-VFA) approach to eliminate the need for a separate B1+ mapping scan while imaging the prostate. The RR-VFA method assumes the existence of a “reference region” that is distributed throughout the volume of interest and is well characterized by a known T1 relaxation time. In particular, fat is generally selected as the reference region due to its distribution in the body. B1+ inhomogeneity is estimated in the fat tissue and interpolated over the entire volume of interest, thus eliminating the need for an additional scan.
    Type: Grant
    Filed: October 29, 2018
    Date of Patent: January 19, 2021
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Kyung Sung, Holden Wu, Novena Rangwala
  • Data write circuit of resistive memory element
    Patent number: 10896729
    Abstract: A data write circuit of a resistive memory element is provided, the device being capable of writing with low writing energy using a simple circuit. The data write circuit of the resistive memory element, includes: a complementary resistive memory element; writing means for making the complementary resistive memory element cause a resistance change; detection means for detecting a writing state in the complementary resistive memory element; and control means for controlling writing by the writing means, based on a detected signal of the detection means.
    Type: Grant
    Filed: October 31, 2017
    Date of Patent: January 19, 2021
    Assignee: TOHOKU UNIVERSITY
    Inventors: Takahiro Hanyu, Daisuke Suzuki, Hideo Ohno, Tetsuo Endoh
  • Holly plant named ‘RutHol4’
    Patent number: PP32759
    Abstract: A new Ilex plant named ‘RutHol4’ is characterized by a combination of an attractive pyramidal growth habit, potential for use in containers or as a small hedge.
    Type: Grant
    Filed: December 5, 2019
    Date of Patent: January 19, 2021
    Assignee: University of Georgia Research Foundation, Inc.
    Inventor: John M. Ruter