Abstract: A highly thermally conductive printed circuit board prevents electrochemical migration by inhibiting elution of copper ions. The printed circuit board is a metal-base printed circuit board including a metal base plate having an insulating resin layer and a copper foil layer stacked thereon in this order. In the printed circuit board, the insulating resin layer contains a first inorganic filler made of inorganic particles having particle diameters of 0.1 nm to 600 nm with an average particle diameter (D50) of 1 nm to 300 nm, and a second inorganic filler made of inorganic particles having particle diameters of 100 nm to 100 ?m with an average particle diameter (D50) of 500 nm to 20 ?m, and the first inorganic filler and the second inorganic filler are uniformly dispersed in the insulating resin layer.

Abstract: Herein provided is a new wheat cultivar designated ‘GA 04434-11E44’ as well as the seeds, plants and derivatives of the new wheat variety ‘GA 04434-11E44’ (such as cultivars and hybrids related thereto). This cultivar is a high grain yielding, medium-late maturing, good test weight, short height line that has good resistance to races of leaf rust and stripe rust in Georgia and the Southeast, powdery mildew, and wheat soil-borne mosaic virus. Also provided are tissue cultures of the new wheat variety ‘GA 04434-11E44’ and the plants regenerated therefrom. Methods for producing wheat plants by crossing the new wheat variety ‘GA 04434-11E44’ with itself or another wheat variety and plants produced by such methods are also provided.

Abstract: The invention provides a novel composite bone graft system utilizing a porous collagen scaffold having a matrix impregnated with calcium phosphate particles and more than one bioactive agent, one of which is conjugated to the matrix. The graft system exhibits increased mechanical strength and osteogenic properties by providing sites for tissue attachment and propagation. The bioactive agents are delivered to the scaffold via different mechanisms to enable sequential and sustained release of the bioactive agents over time.

Abstract: A light emitting diode includes a substrate, a first semiconductor layer, an active layer, a second semiconductor layer, a first electrode, and a second electrode. The first semiconductor layer, the active layer, and the second semiconductor layer are orderly stacked on the substrate. The first electrode is electrically connected to the first semiconductor layer. The second electrode electrically is connected to the second semiconductor layer. The substrate has a number of three-dimensional nano-structures, and each of the number of three-dimensional nano-structures has a stepped structure.

Abstract: An iridium complex represented by formula (1) and an OLED using the same are shown. In Formula (1), l, m, n, p, b, R1-R6, X1-X6, A1, A2 and B are the same as defined in the specification. The iridium complex is able to emit a range of visible light with high color purity and high efficiency as neat sample.

Abstract: The present invention relates to the use of a TLR9 agonist and/or a TLR4 antagonist and/or a NOD2 agonist for treatment or prevention of disorders involving TLR4 activation, such as systemic sepsis and necrotizing enterocolitis.

Abstract: An object of the present invention is to provide a novel endoparasite control agent as a parasiticide, an antiprotozoal or the like. Provided is an endoparasite control agent comprising a carboxamide derivative represented by the general formula (I): or a salt thereof as an active ingredient.

Abstract: An amino acid conjugate of a cyclic or acyclic nucleoside phosphonate is provided. In some cases, the amino acid conjugate is a tyrosine alkyl amide phosphonate ester conjugate of a cyclic or acyclic nucleoside phosphonate, and is useful as an antiviral compound. In certain cases, the tyrosine conjugate includes a long chain alkyl group on the carboxamide group of the tyrosine residue. In a method of preparing an acyclic tyrosine conjugate, a tert-butyloxycarbonyl (Boc) protected tyrosine residue containing a long chain alkyl group is reacted with an acyclic nucleoside phosphonate mono-ethyl ester in the presence of benzotriazol-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate to produce a Boc-protected nucleoside phosphonate di-ester, and the di-ester is deethylated and deprotected to produce the tyrosine conjugate. Methods of inhibiting viral replication and methods of treating a viral infection using the amino acid conjugate are also provided.

Abstract: Antibodies for detecting nitration of nitrotyrosine 247 PKG-1? and antibodies for detecting nitrotyrosine 425 of PKG-1? are disclosed. Methods of detecting nitrotyrosine 247 PKG-1? and nitrotyrosine 425 of PKG-1?, and uses thereof are also disclosed for identification and diagnosis or phenotypes, pathologies, diseases and disorders associated with protein nitration of PKG-1? are also disclosed. In a preferred embodiment, one or more of the disclosed antibodies is used in the disclosed methods.

Abstract: The present invention provides for the identification of individuals having neurodegenerative diseases (ND). Peptoids recognized by Parkinson's Disease- and Alzheimer's Disease-specific antibodies are identified, allowing one to diagnose or predict ND in subjects.

Abstract: In various embodiments, a device for testing a battery may be provided. The device for testing a battery may include: a determination circuit configured to determine at least one of a differential enthalpy of the battery and a differential entropy of the battery; and an evaluation circuit configured to evaluate a health state of the battery based on the determined at least one of the differential enthalpy and the differential entropy.

Abstract: A device for establishing an access channel to a target location is presented. The device includes a plurality of cylindrical segments. A plurality of backbones each extends through a backbone channel of each segment to join the plurality of segments together. When joined together, the central bore of each of the plurality of cylindrical segments align to form an access channel. A distal segment is fixedly attached to each of the plurality of backbones such that an orientation of the distal segment can be adjusted by linear movement of one or more of the plurality of backbones through the plurality of cylindrical segments. Furthermore, when linear movement of the plurality of backbones is restricted, the shape of the access channel can be adjusted by external forces while maintaining the orientation of the distal segment.

Abstract: An isolated or a purified nucleic acid sequence for enhancing expression levels of a protein of interest, in 5? to 3? direction, comprises: a cytomegalovirus (CMV) promoter; an eEF-1 intron repeat (eEF-1 IR); and a regular sequence, which comprises: at least one tag element, a fixable linker sequence, wherein the fixable sequence is TEV sequence; and a multiple cloning site (MCS). By means of the array of the specific promoter and eEF-1 IR, the expression and purity of the recombinant protein could be enhanced; wherein eEF-1 IR can reduce the length of vector and assist RNA polymerase II transcription. Besides, TEV sequence of the fixable linker sequence of the regular sequence can remove a tag on recombinant protein; a specific target can be inserted into the multiple cloning site.

Abstract: An aluminum alloy including additions of scandium, zirconium, erbium and, optionally, silicon.

Abstract: An integrated optofluidic system for trapping and transporting particles for analysis is provided comprising a planar substrate; a microfluidic channel; and a waveguide integrated with the channel. A microsphere particle in the integrated optofluidic system can act as a cavity, allowing light to circulate many thousands of times around the circumference of the microsphere. Optical trapping and transport is used for nanoscale positioning to excite the microsphere resonances. Sensitive measurements on molecules can be accomplished by monitoring changes in whispering gallery modes (WGMs) that propagate around the circumference of the microsphere. By using a broadband or supercontinuum light source, a microsphere can be trapped and many WGM resonances can be excited through the visible and near-infrared wavelengths simultaneously. After the resonances are measured using the waveguide transmission, the microsphere can be freed by decreasing the optical power and the process repeated with a different microsphere.

Abstract: A method and/or system for analyzing data using population clustering through density based merging.

Abstract: The invention is directed to a Ca2+ precipitable polypeptide tags and cassettes useful for purification of molecules from heterogeneous samples. The invention also relates to methods for bioseparation of molecules comprising Ca2+ precipitable tags and cassettes.

Abstract: The present invention relates to the field of virology. More specifically, the present invention provides methods and compositions useful for treating human cytomegalovirus using Wnt pathway modulators. In a specific embodiment, a method for treating human cytomegalovirus (HCMV) in a patient in need thereof comprises administering an effective amount of Wnt pathway modulator.

Abstract: A method for removing elements, including heavy metals, from fly ash and from fly ash resulting from removal of SOx/NOx from flue gas using Na2CO3/NaHCO3/trona, is described. An aqueous suspension of the fly ash and/or a solution of the leachate from the fly ash is treated with dissolved ferrous compounds, such as FeSO4.7H2O and/or FeCl2.4H2O, at a chosen initial acidic pH, and the precipitation of the ferrous ions as the solution basifies sequesters the trace elements.

Abstract: The use of the electride form of 12CaO-7Al2O3, or C12A7, as a low work function electron emitter in a hollow cathode discharge apparatus is described. No heater is required to initiate operation of the present cathode, as is necessary for traditional hollow cathode devices. Because C12A7 has a fully oxidized lattice structure, exposure to oxygen does not degrade the electride. The electride was surrounded by a graphite liner since it was found that the C12A7 electride converts to it's eutectic (CA+C3A) form when heated (through natural hollow cathode operation) in a metal tube.