Abstract: A method of acidizing a subterranean geological formation by injecting an emulsified acid into a wellbore, wherein the emulsified acid includes at least an aqueous phase comprising a hydrochloric acid solution, an oil phase comprising waste oil, and an emulsifier, and wherein the waste oil contains 45-75% by weight of aromatic compounds and preferably contains less than 0.5% by weight of non-hydrocarbon compounds. Various embodiments, and combinations of embodiments, of the emulsified acid and the method of acidizing are provided.

Abstract: The present invention relates to a method for inducing differentiation, into chondrocytes, of cord blood mononuclear cell-derived induced pluripotent stem cells. In a case where a chondrogenic pellet produced by the method of the present invention is transplanted into a cartilage damage area in vivo, regeneration of cartilage can be effectively exhibited by differentiated chondrocytes. In such a case, an effective cartilage regeneration capacity can be exhibited as compared with a case where chondrocytes produced by differentiation induction with the addition of a recombinant growth factor are transplanted. Thus, the present invention can be usefully used for tissue engineering therapies.

Abstract: Provided herein are compounds of Formula (I) and pharmaceutical compositions thereof, which may be useful as MALT1 inhibitors. Also provided are for the treatment of proliferative disorders (e.g., cancer (e.g., non-Hodgkin's lymphoma, diffuse large B-cell lymphoma, MALT, lymphoma), benign neoplasm, a disease associated with angiogenesis, an autoimmune disease, an inflammatory disease, an autoinflammatory disease) by administering a compound of Formula (I).

Abstract: Compositions and methods for inhibition UVB-irradiation damage by administering an effective amount of carnosol are described.

Abstract: The invention provides compositions and methods for treating diseases associated with expression of CD19, e.g., by administering a recombinant T cell comprising the CD19 CAR as described herein, in combination with a kinase inhibitor, e.g., a kinase inhibitor described herein. The invention also provides kits and compositions described herein.

Abstract: The present invention relates to a method of treating or preventing a neurological condition mediated by a tau-dependent signalling complex in neurons of a subject, comprising treating the subject to: (a) promote phosphorylation of one or more amino acids residues of tau, wherein the phosphorylation of the amino acid residues causes disruption of the tau-dependent signalling complex in neurons of the subject; or (b) introduce a variant of tau that causes disruption of the tau-dependent signalling complex in neurons of the subject. The invention also relates to vectors, compositions and kits for treating or preventing a neurological condition mediated by a tau-dependent signalling complex in neurons of a subject.

Abstract: This invention relates generally to a method and system for hybrid classical-quantum communication. The method comprises transmitting a single photon having a particular quantum state over a communication medium using a quantum mode set; and transmitting a classical light beam over the same communication medium using a classical mode set, wherein the classical and quantum mode sets comprise non-separable modes in common. The non-separable modes in common may be two degrees of freedom of a single photon or classical light and may thus be spatial modes in one or more indexes, and polarisation. The invention relates also to a system to implement the method accordingly.

Abstract: The present invention provides a method for 3D waveform mapping of full-parallel structure, first, a 3D waveform mapping database is created according to the size of a 3D waveform image, the number of bits of probability value and the ADC's resolution of data acquisition module, then the 3D waveform mapping database is divided into Mt×Ma independent mapping storage areas along the time axis and the amplitude axis, and each independent mapping storage area is assigned a RAM, then RAMs are selected and addresses are calculated based on the sampling values and the structure of created 3D waveform mapping database, finally, parallel mappings are performed simultaneously on the time axis and the amplitude axis according to the selected RAMs and calculated addresses. Thus, the mapping time are shorten, especially in vector mapping mode, several RAMs are used for mapping, so the WCR of DSO is improved.

Abstract: The disclosed technology includes device, systems, and methods for detecting an analyte using a biosensor. In some implementations, the biosensor may be a transdermal biosensor including a housing material, a nanocellulose material disposed within the housing material, an enzyme entrapped within the nanocellulose material that produces a chemical or biological product when exposed to a vapor or liquid, and a luminescent material within the nanocellulose material that emits visible light upon a chemical or biological reaction with the chemical or biological product.

Abstract: An ion concentration distribution measurement device includes a unit detection element for outputting charges of an amount according to an ion concentration, and an integration circuit for outputting a signal value according to the amount of charges which are output from the unit detection element. The unit detection element includes a MOS transistor, an ion sensitive portion, a first capacitive portion, and a transfer switch. The integration circuit includes an amplifier, a second capacitive portion, and a reset switch.

Abstract: A system and method of treating hyperacusis is presented. The system uses a customizable, patient-specific, in-ear device combining sound attenuation with loudness suppression and a noise generator to expand the dynamic range of a patient. This device is used with novel software and counseling to provide a patient-specific treatment to hypersensitivity to sound.

Abstract: The constrained watershed boundary (CWB), defined as a polygon containing all the flow direction grid cells with a surface flow distance less than a user prescribed threshold uses an algorithm that builds upon the HSM algorithm proposed and augments the data structure with a flow distance grid calculated directly from the original flow direction grid.

Abstract: The present disclosure relates to a system and method for codebook construction and use thereof in image quality assessment. A codebook including a plurality of code words may be provided. Each one of the plurality of code words may have a reference score relating to image quality. A test image may be acquired. One or more feature vectors may be extracted from the test image based on statistical independence between neighboring divisive normalization transform coefficients of the test image. A score may be generated based on a comparison between the extracted feature vectors of the test image and at least some of the plurality of code words in the codebook and the corresponding reference scores of the code words.

Abstract: This invention provides a process for sequencing nucleic acids using 3? modified deoxynucleotide analogues or 3? modified deoxyinosine triphosphate analogues, and 3? modified dideoxynucleotide analogues having a detectable marker attached thereto.

Abstract: A method for reconfigurable optical signal processing. The method includes generating a first pump pulse by propagating a first input pump through a first dispersive medium, generating a first modulated signal by applying a parametric nonlinear wave mixing process on an input optical signal and the first pump pulse, generating a first transformed signal of the input optical signal by propagating the first modulated signal through a second dispersive medium, generating a multiplied signal by multiplying the first transformed signal by a Green's function, generating a second pump pulse by propagating a second input pump through a third dispersive medium, generating a second modulated signal by applying the parametric nonlinear wave mixing process on the multiplied signal utilizing the second pump pulse, and generating a second transformed signal of the multiplied signal by propagating the second modulated signal through a fourth dispersive medium.

Abstract: In the positive electrode active material according to the inventive concept, A positive active material for lithium secondary battery comprises a particle comprising M1, M2, and Li, wherein the particle comprises a center, a surface, and an intermediate portion between the center and the surface, wherein M1 and M2 are selected from transition metal and are different each other, and wherein concentrations of M1 and M2 have continuous concentration gradients from the center to the intermediate portion.

Abstract: Provided is a flexible mechanism. The flexible mechanism comprises: a flexible backbone which is introduced into a treatment area in the human body and which bends along a path in the human body; and a wire for transmitting an operation force provided through a handler prepared at one end of the flexible backbone to an end-effector prepared at the other end of the flexible backbone, wherein the wire extends from the one end of the flexible backbone to the other end of the flexible backbone and can wind around the outer circumferential surface of the flexible backbone in multiples of 360 degrees or passes through a spiral path formed on an inner surface in multiples of 360 degrees.

Abstract: The disclosure in some aspects relates to recombinant adeno-associated viruses having distinct tissue targeting capabilities. In some aspects, the disclosure relates to gene transfer methods using the recombinant adeno-associated viruses. In some aspects, the disclosure relates to isolated AAV capsid proteins and isolated nucleic acids encoding the same.

Abstract: The present invention provides an image encoding method and an image decoding method. The image encoding method of the present invention comprises: a first dividing step of dividing a current image into a plurality of blocks; and a second dividing step of dividing, into a plurality of sub blocks, a block, which is to be divided and includes a boundary of the current image, among the plurality of blocks, wherein the second dividing step is recursively performed by setting a sub block including the boundary of the current images as the block to be divided, until the sub block including the boundary of the current image does not exist among the sub blocks.

Abstract: Provided are a metallic micro/nano-structure and an optical fiber having it on the end-facet. The metallic micro/nano-structure comprises of a metallic film and a micro/nano pattern in the metallic film. The micro/nano pattern divides the metallic film into a periodic structure and an embedded defect structure; the defect structure locally breaks the periodicity of the periodic structure; in at least one dimension, the periodic structure has a period T satisfying 0.75?<T<1.25?, ? is a wavelength of a surface plasmon at an interface between the metallic film and a medium; and the surface plasmon resonates within the defect structure and its surrounding area. The optical fiber end-facet device takes the advantages of single-mode optical fiber systems, including stable optical transmission, compact systems and flexible configurations.