Abstract: A method for determining the risk of cardiovascular disease in a subject having a chronic viral infection includes determining a level of determining a level of at least one lysophophatidic acid (LPA) subtype in the subject, wherein the LPA subtype is selected from the group consisting of LPA 16:0, 18:1, 18:2, and 20:4 and comparing the determined level of the at least one LPA to a control level, wherein an increased level of at least one LPA subtype is indicative of the subject having an increased risk of cardiovascular disease associated with the chronic viral infection.

Abstract: Compounds having inhibitory activity against retinaldehyde dehydrogenases (RALDHs). The compounds can be used, for example, to inhibit synthesis of retinoic acid for the treatment of refractive error disorders such as myopia, and as infertility treatments by inhibiting spermatogenesis.

Abstract: A fluid sensing device includes an outer shell, a three-axis force and moment balance, a strut, and a centerbody. The outer shell has an inlet at a first end of the outer shell, an aft vent at an opposing second end of the outer shell, and an interior space connecting the inlet and the aft vent. The three-axis force and moment balance is positioned in the interior space of the outer shell. The strut is connected to the outer shell and the three-axis force and moment balance such that the strut supports the three-axis force and moment balance in the interior space. At least a portion of the centerbody is positioned in the interior space of the outer shell. The centerbody is connected to the three-axis force and moment balance such that the three-axis force and moment balance is configured to measure force, moment, and/or movement of the centerbody.

Abstract: The present disclosure provides an implantable device comprising a substrate capable of capturing an intraocular target molecule and to methods of use thereof.

Abstract: The disclosure provides monoclonal bispecific antibodies targeting HER2 and HER3. The disclosure also provides monospecific tetravalent HER3 antigen binding antibodies. Still further provided by the disclosure are methods of treating a cancer in a subject, comprising administering to the subject a therapeutically effective amount of an antibody provided by the disclosure.

Abstract: The present invention discloses methods and systems to control magnetic fields and magnetic field induced currents, and more particularly to provide stimulations within a patient's body, such as deep brain stimulation, in a non-invasive manner and with greater focus and control than has been afforded by prior known methods and systems. In accordance with certain aspects of an embodiment, an array of magnetic coils is provided and positionable about a portion of a patient's body. During operation, at least some of the magnetic coils function as DC coil pairs configured to generate a DC magnetic field, while at least some DC coil of the other magnetic coils function as transient magnetic field generators to generate an induced current within a portion of the patient's body, such as in a region of the patient's brain.

Abstract: An apparatus and method for diagnosing rotor shaft are disclosed herein. The apparatus for diagnosing a rotor shaft that is installed in a bearing so that the rotor shaft is rotated around an axis of rotation includes a measurement unit, a calculation unit, an image generation unit, and a diagnosis unit. The measurement unit measures first vibration signals at two points of the rotor shaft located on a surface perpendicular to the axis of rotation. The calculation unit generates second vibration signals, which are vibration signals at points located in a plane identical to the plane of the two points of the rotor shaft at which the first vibration signals are measured, based on the first vibration signals. The image generation unit generates an image based on the second vibration signals. The diagnosis unit diagnoses the rotor shaft based on the generated image.

Abstract: The present invention relates to method for simulating mandibular movements, device for the same and recording medium for recording the same. With the method for simulating mandible movements according to the present invention, it is possible to perform the simulation directly on the medical image of the patient and thus simulate the mandibular movements more closely to the actual situation. Therefore, the inaccurate mechanical approximation of the mandibular movement with the articulator according to the conventional art is overcome. In addition, according to the present invention, it is possible to simulate mandibular movements customized to the various states of the patient and specific clinical cases.

Abstract: Embodiments of the present disclosure provide for radionuclide probes, methods of using the radionuclide probes, methods of detecting an optical signal from radionuclides, methods of detecting an optical signal from a quantum dot(s) that receives optical energy from a radionuclide(s), system for analyzing optical energy emitted by a radionuclide(s), system for imaging a target within a living subject or a sample, methods of imaging a disease or condition, and the like.

Abstract: The present invention provides a process for recycling waste carbide, wherein the waste carbide is directly used as anode and electrolyzed in the molten salt, comprising the following steps: 1) the vacuum dehydrating of the molten salt electrolyte; 2) electrolyzing the waste carbide, which is used as anode, and an inert electrode, which is used as cathode in the molten salt electrolyte with the electrolysis temperature of 350˜1000° C.; 3) separating and collecting the metal powder obtained by electrolysis from molten salt medium. According to the technical solutions of the present invention, tungsten and cobalt ions can be dissolved from the anode material-waste carbide directly into the molten salt medium and deposited on the cathode plate with being driven by the electrolysis voltage, to obtain the metal powder particles. The tungsten, cobalt and other products obtained by electrolysis can be used as carbide materials, high temperature structural materials, weapons materials, photocatalytic materials, etc.

Abstract: An improved method of clustering wireless sensor networks includes selecting cluster heads in the network based on a score calculated for each node. The score is calculated based on one or more predetermined criteria of each node and determines which node is selected as a cluster head among one or more nodes in the vicinity of each other. As a result, the score of each cluster head node at the time of its selection is higher than or the same as its cluster node members. Moreover, the cluster heads may be selected such that they are not located in close proximity to each other and are fairly distributed in the environment. The duration of this decentralized clustering process is finite and predetermined and does not depend on the number of nodes and the size of the network.

Abstract: This disclosure provides systems, methods, and apparatus related to thermoelectric polymer aerogels. In one aspect, a method includes depositing a solution on a substrate. The solution comprises a thermoelectric polymer. Solvent of the solution is removed to form a layer of the thermoelectric polymer. The layer is placed in a polar solvent to form a gel comprising the thermoelectric polymer. The gel is cooled to freeze the polar solvent. The gel is placed in a vacuum environment to sublimate the polar solvent from the gel to form an aerogel comprising the thermoelectric polymer.

Abstract: The presently disclosed subject matter describes the use of fluorinated elastomer-based materials, in particular perfluoropolyether (PFPE)-based materials, in high-resolution soft or imprint lithographic applications, such as micro- and nanoscale replica molding, and the first nano-contact molding of organic materials to generate high fidelity features using an elastomeric mold. Accordingly, the presently disclosed subject matter describes a method for producing free-standing, isolated nanostructures of any shape using soft or imprint lithography technique.

Abstract: Immune-polyelectrolyte multilayers (iPEMs) that can be made entirely from immune signal compounds are provided. The iPEMs are formed from first layer of a first immune signal compound, and a second layer of the first immune signal compound or a second immune signal compound disposed on the first layer of the first immune signal compound. The immune signal compounds are peptides, polypeptides, nucleic acids, charged derivatives thereof. Combinations of the immune signal compounds may be in adjacent layers. The first immune signal compound and the second immune signal compound have oppositely charged domains. iPEMs can be formed on or include a substrate, such as a sacrificial substrate, which allows for the formation of a three-dimensional void which can hold various other compounds for use in modulating immune responses. The iPEMs are for use in either stimulating an immune response to one or more antigens, or inducing tolerance to one or more antigens.

Abstract: The present invention relates to a magnetic device including a spin-current pattern generating a spin current perpendicular to a main plane of the spin-current pattern by an in-plane current, and a free magnetic layer disposed in contact with the spin-current pattern and having a perpendicular magnetic anisotropy magnetically switchable by the spin current.

Abstract: Disclosed are an uplink resource allocation method and a cognitive small cell network system performing the method. In the method, a small cell manager collects an access request from a small cell user and forms a preference relationship for each small cell user. Then, sub-channel-specific transmission power for providing a maximum data transmission rate at the time of uplink transmission is calculated and the calculated sub-channel-specific transmission power information is transferred to the small cell user. Meanwhile, the small cell user forms all possible sub-channel-specific preference relations and thereafter, transmits the access request for each sub-channel having a maximum preference relationship to the small cell manager.

Abstract: Disclosed herein is a pharmaceutical composition for preventing, alleviating or treating neurodegenerative diseases. The pharmaceutical composition contains, as active ingredients, Curcumae longae rhizome, Gastrodiae rhizoma, Polygalae radix, Salviae radix, Chaenomeles fructus, Paeoniae radix, Glycyrrhizae radix, Atractylodis rhizome, and Pulvis aconiti tuberis purificatum. The pharmaceutical composition is prepared by a method including the steps of: mixing Curcumae longae rhizome, Gastrodiae rhizoma, Polygalae radix, Salviae radix, Chaenomeles fructus, Paeoniae radix, Glycyrrhizae radix, Atractylodis rhizome, and Pulvis aconiti tuberis purificatum to obtain a mixture, and extracting the mixture to obtain a mixture extract; filtering the mixture extract; concentrating the mixture extract; and drying the mixture extract.

Abstract: The present invention includes a system, apparatus and method for generating a three-dimensional image, the system comprising: a medium comprising a optical molecular switch molecule, wherein the optical molecular switch molecule has a non-fluorescent state and a fluorescent state, wherein at one wavelength of optical excitation the molecule has a first state, and at a second state the molecule fluoresces a second wavelength of excitation; and at least a first light source and a second light source into the medium, wherein light emitted by the at least first and second light sources are directed to contact the optical molecular switch molecule, e.g., scanning, weaving, diagonally or other pattern; wherein the optical molecular switch molecule is converted into a fluorescent “on state” by irradiation from the first light source, and the second light causes the optical molecular switch to emit light.

Abstract: The present invention aims to provide a method of producing motor neurons/neurons that sufficiently reproduce intrinsic properties of motor neurons/neurons, especially of the motor neurons/neurons in patients, from pluripotent stem cells promptly and synchronically, and a pluripotent stem cell capable of differentiating into a neuron or a motor neuron promptly and synchronically after a drug treatment. A method of generating a motor neuron from a pluripotent stem cell, comprising the following steps in order from (1) to (2): (1) introducing one or more nucleic acids encoding Lhx3, Ngn2, and Isl1 into a pluripotent stem cell; and (2) maintaining expression of the Lhx3, Ngn2, and Isl1 for three days or more.

Abstract: Disclosed herein is a method and system for using ferrite cores to suppress harmonic radiation with microstrip patch antennas. In certain embodiments, the ferrites cores exemplified herein significantly suppressed second and third harmonic radiation generated by RF components coupled to the microstrip patch antenna.