Abstract: Devices, systems, and techniques are disclosed for intelligent semiconductor based medical tweezers and instrumentation including microscale sensors, actuators and circuitry for tissue detection and characterization. In one aspect, a tweezer device includes a hinge structure to enable tweezing motion of the device for clamping a sample, two leg components coupled to the hinge structure, a plurality of microprobes configured on both of the two leg components, and an electronic circuit electrically coupled to the microprobes to process and/or transmit the electronic signals. The microprobes include sensors in a sensing tip structured to penetrate into the sample when the device clamps the sample and produce electronic signals from the sensors of a property of the sample, the sensors of the sensing tip including at least one of an electrode to measure an electrical potential, an electrical permittivity sensor to measure electrical permittivity, or a strain gauge to measure mechanical compliance.

Abstract: A method for residual oil recovery from oil reservoirs, and diagnostic tests for determining its efficiency using a single well are described. The method includes injecting oil into a well in a reservoir that has been previously waterflooded or an oil reservoir or zone of an oil reservoir which contains immobile oil at the time of discovery, and extracting the oil by waterflooding the charged zones by placing the injection well in production. The target zone from which oil is recovered may be increased by following injection of oil with injection of water to push an oil bank which grows in volume as a function of distance of propagation, because of the effect of waterflooding on residual oil. The well may then be placed in production and the oil bank volume will continue to increase in volume as it returns to the well, again because of the waterflooding effect. The oil bank is then produced at the surface.

Abstract: Reactive sulfur species have been recognized as an important regulator in redox biology, wherein the reactive sulfur species have been shown to be active in tumor suppressors, ion channels, and transcription factors. The disclosed invention is a novel composition of matter that allows for the detection of H2S and H2Sn species in living cells. These novel compositions represent significant progress in the field of chemical, H2S and H2Sn probes as they have both been successfully applied in the visualization sulfur species in living systems.

Abstract: A compound represented by formula (I) or formula (II): in formula (I), R3 represents an electron donating group, R4 represents a hydrogen atom, a substituted or unsubstituted aryl group or an electron donating group, L3 represents a substituted or unsubstituted heteroarylene group or a substituted or unsubstituted arylene group, L4 represents a single bond, a substituted or unsubstituted heteroarylene group or a substituted or unsubstituted arylene group, L3 and L4 may bond together to form a ring with the carbon atoms to which they are bonded, in formula (II), R5 represents an electron donating group, R6 represents a hydrogen atom, a substituted or unsubstituted aryl group or an electron donating group, L5 represents a substituted or unsubstituted heteroarylene group or a substituted or unsubstituted arylene group, L6 represents a single bond, a substituted or unsubstituted heteroarylene group or a substituted or unsubstituted arylene group.

Abstract: Techniques are presented for fabricating transducers and other types of microstructures having high aspect ratios. To achieve high aspect ratios, wafers are etched from both sides for example using deep reactive ion etching. The three-dimensional structure is designed to have an overall footprint less than four hundred micrometers with a thickness on the order of 0.5-2 millimeters as compared to conventional planar devices.

Abstract: A system and method for joint dynamic interest request forwarding and dynamic cache placement and eviction and provided within the context of the Named Data Networking (NDN) architecture. The system and method employ a virtual control plane that operates on the user demand rate for data objects in the network, and an actual plane that handles Interest Packets and Data Packets. Distributed algorithms within the virtual plane achieve network load balancing through dynamic forwarding and caching, thereby maximizing the user demand rate that the NDN network can satisfy. A method of congestion control is also provided to achieve optimal network fairness using the VIP framework.

Abstract: A bending mold device for bidirectional pipe bending includes a mounting base which is horizontally arranged on a rack in a sliding manner. The mounting base includes a translation lead screw driving the mounting base to slide. The rack includes a lead screw nut. A pipe bending spindle is rotatably disposed on the mounting base and a power mechanism is disposed on the mounting base. The upper end of the pipe bending spindle is movably connected to a lower rotating base. The lower rotating base includes a first pipe bending shaft and a second pipe bending shaft, which respectively include a first bending mold lower mold and a second bending mold lower mold. The rack includes a cylinder above the lower rotating base. The end part of a piston rod of the cylinder fixedly includes an upper limiting plate and a lower limiting plate in a sleeving manner.

Abstract: A method for producing an image representative of the vasculature of a subject using a MRI system includes the acquisition of a signal indicative of a subject' cardiac phase. During each heartbeat of the subject, image slices of a volume covering a region of interest (ROI) within the subject are acquired by applying a volume-selective venous suppression pulse to suppress (a) venous signal for an upper slice in the ROI; (b) venous signal for slices that are upstream for venous flow in the ROI; and (c) background signal from the upstream slices. Next, a slice-selective background suppression pulse is applied to suppress background signal of the upper slice. Following a quiescent time interval, a spectrally selective fat suppression pulse is applied to the entire volume to attenuate signal from background fat signal. Then, a simultaneous multi-slice acquisition of the upper slice and the upstream slices is performed.

Abstract: Systems and methods herein produce an isolated carbon particle embedded diamond-like carbon (DLC) coating having increased toughness, increased hardness, and enhanced wear resistance. In embodiments, a physical vapor deposition (PVD) chamber houses a pure graphite target at a distance from a substrate, and an in-situ synthesis of isolated carbon particles simultaneous with hydrogen-free DLC coating deposition is provided through unbalanced magnetron sputtering by localized injection of helium gas in a pulse mode with different durations. The resultant coating may include carbon while omitting other elements, and the carbon particles form covalent bonding with the host DLC matrix. Processes disclosed herein are easier to control and manipulate as compared to traditional metal doped DLC coatings.

Abstract: A method of fabricating a positive active material for a rechargeable sodium battery is provided. The method includes forming a metal hydroxide precursor including nickel, cobalt, and manganese, and fabricating a positive active material by mixing and firing the metal hydroxide precursor and a sodium source. A kind of the sodium source is changed depending on a content of nickel or manganese included in the metal hydroxide precursor.

Abstract: Disclosed herein are borazine complexes and use of the same in perfluoroalkylation reactions.

Abstract: The present invention provides systems and methods for embedding a filament or filament mesh in a three-dimensional structure, structural component, or structural electronic, electromagnetic or electromechanical component/device by providing at least a first layer of a substrate material, and embedding at least a portion of a filament or filament mesh within the first layer of the substrate material such the portion of the filament or filament mesh is substantially flush with a top surface of the first layer and a substrate material in a flowable state is displaced by the portion of the filament and does not substantially protrude above the top surface of the first layer, allowing the continuation of an additive manufacturing process above the embedded filament or filament mesh.

Abstract: The disclosed provides a posture-guided cross-category method and device for combination modeling of cross-category 3D models, the method including: receiving a first posture model inputted by a user; calculating similarities between q first regions of the first posture model and q second regions of each of second posture models in a preset model database, respectively; where the model database includes a plurality of models partitioned into model components, and second posture models corresponding to the models; where the q first regions correspond to the q second regions one on one, where q is an integer greater than or equal to 2; selecting a corresponding plurality of model components of the q second regions of the second posture model according to the similarities; and combining the selected plurality of model components to generate a 3D model. The embodiment of the present application can combine cross-category models with large structural differences.

Abstract: Methods are disclosed for treating cell components, cells, organelles, organs, and/or tissues with acoustic energy, electromagnetic energy, static or alternating electric fields, and/or static or alternating magnetic fields in the presence or absence of exogenous particulate agents for therapeutic applications.

Abstract: An electrochemical screening method for the selection of DNA aptamers against 11-deoxycortisol (11-DCL) using gold electrode for target immobilization is described. The gold electrode is used as solid matrix instead of the beads for SELEX. The selection steps (SELEX) are performed on the 11-DC modified electrode directly as the DNA library in the first round or the enriched DNA pools in the subsequent rounds were incubated on the electrode, then the unbound DNA is washed and the bound DNA is measured directly by square wave voltammetry. Then elution of the bound DNA is performed for further use.

Abstract: Provided is a novel method of suppressing non-specific protein adsorption. The above-mentioned object can be achieved by treating a solid phase with a solid phase-treating liquid containing a phosphorylcholine group-containing polymer as a main component, and treating a specimen with a specimen-treating liquid containing, as a main component, a polymer having a phosphorylcholine group, a hydroxy group, and a hydrophobic group, followed by addition of the treated specimen to the treated solid phase.

Abstract: Methods of treating a dengue virus (DENV) infection in a human subject, comprising administering to the human subject a compound of Formula (I), or pharmaceutical composition comprising a compound of Formula (I): A compound of Formula (I) can be administered within onset of fever to 72 hours of fever onset due to dengue infection and then every 6 to 12 hours until there is an improvement in the infection or between from about 1 day to about 10 days. The methods of the invention can be used to treat primary and secondary DENV 1-4 viral infections.

Abstract: Nanoscale coordination polymer nanoparticles for the co-delivery of multiple therapeutic agents are described. The multiple therapeutic agents can include a combination of different chemotherapeutic agents, a combination of one or more chemotherapeutic agents and one or more nucleic acids, such as small interfering RNA (siRNA) or microRNA, a combination of one or more chemotherapeutic agents and a photosensitizer (i.e., for use in photodynamic therapy), or a plurality of different siRNAs. Pharmaceutical formulations including the nanoparticles, methods of using the nanoparticles to treat cancer, and methods of making the nanoparticles are also described.

Abstract: The present invention discloses a method of re-transmission of a lost MMT packet by a packet transmission apparatus. The method includes generating a media processing unit (MPU) based on a media fragment unit (MFU) and generating an MMT asset by encapsulating the MPU; generating an MMT packet based on the MPU included in the generated MMT asset; and transmitting the generated MMT packet, wherein the method further comprises adding, in a signaling message related to re-transmission of the MMT packet, delay_constrained_ARQ_flag to indicate whether or not the MMT packet transmission apparatus supports a delay-constrained automatic repeat request (ARQ) function.

Abstract: The present invention relates anti-HIV therapies and prophylaxis. Specifically, the invention relates to broadly neutralizing antibodies against HIV-1, nucleic acids encoding these antibodies, vectors comprising the nucleic acids and cells and pharmaceutical compositions Comprising said vectors and/or antibodies. The present invention also relates to use of the antibodies and/or vectors for the treatment and/or prevention of HIV-1 infection in a subject. Furthermore, the invention also relates to a kit containing the antibodies of the invention.