Abstract: The present invention is directed generally to chimeric proteins that can facilitate targeting of nanoparticulate carriers to antigen presenting cells, and to nanoparticulate carriers comprising these chimeric proteins. The invention is also directed to methods of internalizing an antigen in an antigen presenting cell, and methods of eliciting an immune response to an antigen in a subject, using the nanoparticulate carriers comprising the chimeric proteins.

Abstract: Disclosed are various embodiments that enable the identification of the location of a computing device based on radio data. A radio map can be identified for an area. The computing device can measure signal strengths to reference points. The signal strengths can be compared to the radio map. The computing device can determine its location based on the comparison of the signal strengths to the radio map.

Abstract: An ion-trap system having a trapping location that is controllable with nanometer-scale precision in three dimensions is disclosed. The ion-trap system includes an ion trap that includes a pair of RF driver electrodes, a pair of tuning electrodes operably coupled with the RF driver electrodes to collectively generate an RF field having an RF null that defines the trapping location, as well as a plurality of DC electrodes that are operably coupled with the RF driver electrodes and the tuning electrodes. Each tuning electrode is driven with an RF signal whose amplitude and phase is independently controllable. By controlling the amplitudes of the RF signals applied to the tuning electrodes, the height of the trapping location above the mirror is controlled. The position of the tuning location along two orthogonal lateral directions is controlled by controlling a plurality of DC voltages applied to the plurality of DC electrode pads.

Abstract: Catalysts, catalytic systems and related synthetic methods for in situ production of H2O2 and use thereof in reaction with oxidizable substrates.

Abstract: A print head assembly for printing an ink on a substrate having a printing pin member having a tip; a wetting system having an ink reservoir, the wetting system being configured to transfer ink from the ink reservoir to the tip of the printing pin member; and a charging system operably coupled to the printing pin member, the charging system configured to apply a high voltage charge to the printing pin member resulting in the ink on the tip of the printing pin member to be deposited upon the substrate.

Abstract: The present invention relates to a compound of formula I, a stereoisomer, a prodrug, a pharmaceutically acceptable salt thereof or a pharmaceutically acceptable solvate thereof, and a process for preparing the same, a pharmaceutical composition comprising the same, and use of the compound in the preparation of medicine preventing and treating tumors, wherein the substituents are as defined in the specification.

Abstract: Cyclic-GMP-AMP synthase (cGAS) and cyclic-GMP-AMP (cGAMP), including 2?3-cGAMP, 2?2-cGAMP, 3?2?-cGAMP and 3?3?-GAMP, are used in pharmaceutical formulations (including vaccine adjuvants), drug screens, therapies, and diagnostics.

Abstract: Microfluidic devices are provided for trapping, isolating, and processing single cells. The microfluidic devices include a cell capture chamber having a cell funnel positioned within the cell capture chamber to direct a cell passing through the cell capture chamber towards one or more a cell traps positioned downstream of the funnel to receive a cell flowing. The devices may further include auxiliary chambers integrated with the cell capture chamber for subsequent processing and assaying of the contents of a captured cell. Methods for cell capture and preparation are also provided that include flowing cells through a chamber, funneling the cells towards a cell trap, capturing a predefined number of the cells within the trap, interrupting the flow of cells, flowing a wash solution through the chamber to remove contaminants from the chamber, and sealing the predefined number of cells in the chamber.

Abstract: According to embodiments of the present invention, a lighting apparatus is provided. The lighting apparatus includes at least one light source configured to provide a source light, an optical waveguide optically coupled to the at least one light source, the optical waveguide having at least one input region through which the source light enters the optical waveguide for propagation within the optical waveguide, and a plurality of light interacting structures arranged within the optical waveguide, the plurality of light interacting structures adapted to interact with the source light to provide an illumination light emitted from the optical waveguide to an ambient environment, wherein a concentration of the plurality of light interacting structures increases, along a length portion of the optical waveguide, in a direction away from the at least one input region.

Abstract: The present invention provides an implantable cardiac compression device comprising: an inflatable cardiac compression jacket configured when inflated to directly compress a heart and assist in displacing blood therefrom, a channel that connects the inflatable cardiac compression jacket and an expandable fluid reservoir configured to contain a fluid when displaced compresses the inflatable cardiac compression jacket, and a fluid driver operably connected to the inflatable cardiac compression jacket and to the expandable fluid reservoir, wherein the fluid driver is configured to inflate the cardiac compression jacket and to deflate the expandable fluid reservoir during systole of the heart; said driver is further configured to deflate the cardiac compression jacket and to inflate the expandable fluid reservoir during diastole of the heart.

Abstract: An inexpensive, biodegradable, easily transportable mosquito trap and improved attractant formulation and apparatus are provided.

Abstract: Provided are an organic light-emitting display apparatus and a method of manufacturing the same. The organic light-emitting display apparatus includes a first substrate; an organic light-emitting device provided on the first substrate and including a first electrode, a second electrode, and an intermediate layer positioned between the first electrode and the second electrode; a second substrate covering the organic light-emitting device and disposed to face the first substrate; and a sealant bonding the first substrate and the second substrate, wherein at least a portion of the sealant is a intermixing region which is formed as an inorganic material permeates an organic material.

Abstract: A multi-axis measurement device for loading force and center of gravity is provided comprising a first loading plate, and comprising: a first slidable element and a first piezoelectric pressure sensing element. A second loading plate comprising: a second slidable element and a second piezoelectric pressure sensing element. A connecting plate, respectively connects to the first slidable element, the first piezoelectric pressure sensing element, the second slidable element, and the second piezoelectric pressure sensing element. A plurality of third piezoelectric pressure sensing elements connects to the first loading plate. The first piezoelectric pressure sensing element measures the changes in force of the X-axis direction, the second piezoelectric pressure sensor element sensing element measures the changes in force of the Y-axis direction, and the third piezoelectric pressure sensor element sensing elements measure the changes in force of the Z-axis direction.

Abstract: A device may include a flexible substrate. The device may further include a flexible integrated circuit within the flexible substrate, the integrated circuit having at least one input electrode positioned on a surface of the flexible substrate. The device may also include an aerosol jet printed conductive ink layer disposed on the surface of the flexible substrate, the aerosol-jet printed conductive ink layer having a pattern that includes a first set of fingers interdigitated with a second set of fingers, the aerosol jet printed conductive ink layer in contact with the at least one input electrode.

Abstract: A method for purifying polybutylene terephthalate (PBT) includes: providing or receiving initial PBT, in which oligomers and tetrahydrofuran are present; dissolving the initial PBT in hexafluoroisopropanol (HFIP) to form a solution, in which the oligomers are also dissolved in the HFIP; and contacting the solution with compressed CO2 at a temperature and a pressure, thereby precipitating the purified PBT, resulting from a large portion of the oligomers are still dissolved in the HFIP, in the operation the temperature is in a range of 20° C. to 35° C., and the pressure is in a range of 900 psi to 1400 psi. A device for purifying PBT is also provided.

Abstract: An operating method of the soft-verify write assist circuit of the resistive memory provides a voltage level applying step, a write operating step and a write voltage controlling step. The voltage level applying step is for applying a plurality of voltage levels to the reference voltage, the word line and the switching signal, respectively. The write operating step is for driving the memory cell to perform in a set process or a reset process via the first three-terminal switching element, the second three-terminal switching element and the soft-verify controlling unit during a write operation. The write voltage controlling step is for controlling the write voltage to be increased in the ramping cycle and decreased in the soft-verify cycle.

Abstract: A superhydrophobic appliance is an elastomeric material with a surface having a multiplicity of re-entrant features. The elastomeric material can be a polydimethylsiloxane network. The superhydrophobic appliance can be formed by infusing a portion of a polydimethylsiloxane polymeric precursor partially into the pores of a porous membrane, curing to the polymeric network, and separating the membrane from the appliance to expose the superhydrophobic surface. The superhydrophobic surface can be subsequently modified to form a fluorinated surface that is oleophobic or superoleophobic in addition to being superhydrophobic.

Abstract: A system and method for adaptively utilizing transmitter windowing, receiver windowing and alignment signals for minimizing interference and maximizing capacity and energy efficiency based upon the received power ratios of links in adjacent bands of a cellular communication network.

Abstract: The present invention relates to novel hydroxamic acids which are specific histone deacetylase (HDAC) inhibitors and/or TTK/Mps1 kinase inhibitors, including pharmaceutically acceptable salts thereof, which are useful for modulating HDAC and/or TTK/Mps1 kinase activity, pharmaceutical compositions comprising these compounds, and processes for their preparation.

Abstract: Described herein is a new and distinct rose plant named ‘80103WABARA’ that has large, white, star-shaped flowers with dense petals. The variety is primarily used as a potted plant and for cut flowers.