Abstract: SP1 and modified SP1 variant polypeptides capable of forming reversible molecular associations with substances, compositions-of-matter comprising same, and uses thereof are provided.

Abstract: A medical procedure training system and method for using is provided. The system includes a sensing system structured to detect the position and motion of a medical device inserted into a simulated body, a processor structured to generate images of the medical device and relevant anatomical structures based on the detected position and motion of the medical device, and a display system structured to display the images in a correct registration on the outer surface of the simulated body.

Abstract: The present invention relates to a method for sensitizing a disease cell expressing the epidermal growth factor receptor (EGFR) to a tyrosine kinase inhibitor selective or specific for EGFR and/or its signalling pathway, the method comprising contacting the cell with a miR-7 miRNA, a precursor or variant thereof, or a miRNA comprising a seed region comprising the sequence GGAAGA.

Abstract: Disclosed herein are methods for treating, inhibiting, or reducing ischemia/reperfusion injury of a cardiac tissue; increasing phosphorylation of ERK1/2 and/or eNOS in a cardiac tissue; treating, inhibiting, or reducing loss of NO; treating, inhibiting, or reducing uncoupling of NOS; increasing recoupling of NOS; treating, inhibiting, or reducing loss of DCC protein and mRNA expression in a cardiac tissue; decreasing or reducing the infarct size of a heart resulting from ischemia/reperfusion injury; decreasing or reducing superoxide production by a cardiac tissue caused by ischemia/reperfusion injury; treating, inhibiting, or reducing neointimal formation and restenosis; treating, inhibiting, or reducing apoptosis of mobilized endothelial progenitor cells; or a combination thereof of a blood vessel (such as an artery, a coronary artery, a vein, or a capillary) or a portion of the blood vessel in a subject which comprise the administration of netrin-1.

Abstract: A method for producing a solid layer material (42), comprising providing (70) a first layer (30); providing (72) a second liquid layer (32) on the first layer (30); providing (74) a third liquid layer (34) on the second liquid layer (32), wherein the third liquid layer has a melting point that is higher than a melting point of the second liquid layer, and wherein the second liquid layer is between the first and third layers; cooling (76) a surface of the third liquid layer to a temperature less than the melting point of the third liquid layer; forming (78) the solid layer from the third liquid layer while cooling the third layer liquid; and removing (80) the solid layer.

Abstract: An optical sensor based on a broadband light source and cascaded waveguide filters comprises a broadband light source, an input waveguide, a reference ring resonator coupled with the input waveguide, a common bus waveguide coupled with the reference ring resonator, a sensing ring resonator coupled with the common bus waveguide, an output waveguide coupled with the sensing ring resonator, and two optical power detectors. At least a portion of the sensing ring resonator is influenced by the physical parameter to be measured or in contact with an analyte. The variation of the physical parameter to be measured or the variation of the analyte induces a shift of the transmission spectrum of the sensing ring resonator. By using the cascaded filtering effect of the double resonators, the wavelength shift can be translated into a variation of the total output power. Consequently the physical parameter to be measured can be easily deduced.

Abstract: A cathode composition of lithium ion battery includes a number of nanoparticles and coating material coating outer surfaces of the nanoparticles.

Abstract: A nanocomposite material for use as an electromagnetic wave or radio frequency absorber or as a filter to trap or remove heavy metals. The nanocomposite material may be made with a one-pot synthesis, or thermodecomposition process, of magnetic graphene nanocomposites decorated with core-double-shell nanoparticles, wherein the double shell iron nanoparticles may comprise a crystalline iron core, an inner iron oxide layer around the crystalline iron core, and an outermost amorphous Si—S—O compound shell around the iron oxide layer.

Abstract: By stacking and mounting a second substrate 20 having the same structure as that of a first substrate 10 on the first substrate upon rotating the second substrate by 180 degrees and sliding the second substrate, an antenna 11 and an antenna 22 overlap each other and an antenna 12 and an antenna 21 overlap each other and communications in each of these combinations are enabled, and a space for wire bondings 16 is secured. Accordingly, communications between the substrates are made via the antennas, and further, a space for wire bondings is secured on each substrate, wireless communications are carried out between substrates which have the same basic structure and are stacked and mounted, and power can be supplied via the wire bondings.

Abstract: A self-expanding bone screw anchor assembly adapted to allow the screw body to engage the bone and the anchor to attach thereto. The anchor assembly is adapted to be universally deployed with a variety of installation tools.

Abstract: Flush preservation solution for the preservation of cells in the absence of a blood supply comprising: v) water for injection; and vi) at least one saccharide such as a monosaccharide, disaccharide, trisaccharide, or polysaccharide and vii) at least one component with pH buffer properties; and viii) at least one component with calcium transport blocking properties or an anti-calcium action activity; method for the preparation thereof; use thereof in transplantation including organs from heart beating or non heart beating donors, in surgery including any situation of warm or cold ischaemia, cardioplegia or open heart surgery, whole limb or whole body preservation in experimentation on living tissues or in culturing and preserving engineered cells, tissues and organs, limbs or the whole body; method for flushing, preserving or flush preservation of cells; and a kit of parts comprising the solution components.

Abstract: A device and method for facilitating access to a perimeter surface of a body structure is provided. The device includes an elongate flexible member configured to be positioned adjacent the perimeter surface of the body structure, an atraumatic tip positioned at a distal end of the elongate flexible member, and an elongate body. The elongate body has a surface positioned to guide the elongate flexible member and to permit longitudinal movement of the flexible member with respect to the elongate body. The body also has a curved distal portion and a distal end for releasably engaging the atraumatic tip.

Abstract: A fault detection method in a continuous annealing process based on a recursive kernel principal component analysis (RKPCA) is disclosed. The method includes: collecting data of the continuous annealing process including roll speed, current and tension of an entry loop (ELP); building a model using the RKPCA and updating the model, and calculating the eigenvectors {circumflex over (P)}. In the fault detection of the continuous annealing process, when the T2 statistic and SPE statistic are greater than their confidence limit, a fault is identified; on the contrary, the whole process is normal. The method mainly solves the nonlinear and time-varying problems of data, updates the model and calculates recursively the eigenvalues and eigenvectors of the training data covariance by the RKPCA. The results show that the method can not only greatly reduce false alarms, but also improve the accuracy of fault detection.

Abstract: The present invention relates to an alternative strategy for expressing the antisense sequence of a miRNA. This system allows for continuous production of the antisense sequence and subsequently complete knockdown of the targeted miRNA.

Abstract: In one embodiment, an atomic clock for use in an electronic device includes a photodetector with a single-isotope silicon crystal doped with impurity atoms in which a photocurrent generated via a two-photon process within the photodetector is used as a frequency resonance of the atomic clock.

Abstract: An osmolyte composition comprising 4 M glycerol and 4M urea for stabilizing previously transient protein folding intermediates as long-lived stable forms. A method to search for other possible stabilizing osmolyte mixtures using a screening array is also provided. These additional osmolyte mixtures may complement or augment the successful 4M glycerol/4 M urea mixture.

Abstract: An impedance analyzer includes: a control voltage generating unit for generating a control voltage that has a predetermined amplitude value; a measuring unit operable to provide an output current, which has an amplitude value corresponding to that of the control voltage, for flowing through first and second body portions of a biological target, and to generate a measurement voltage that has an amplitude value corresponding to a difference between voltages at the first and second body portions attributed to flow of the output current therethrough; and a calculating module operable to determine an electrical impedance between the first and second body portions according to a predetermined adjustment value and the amplitude value of the measurement voltage.

Abstract: Improved anti-HPV immunogens and nucleic acid molecules that encode them are disclosed. Immunogens disclosed include those having consensus HPV 6, HPV 11, HPV 33 and HPV58 E6 and E7. Pharmaceutical composition, recombinant vaccines comprising and live attenuated vaccines are disclosed as well methods of inducing an immune response in an individual against HPV are disclosed.

Abstract: A vibration damping device for suppressing vibrations of a structure includes: a slide body mechanism having a concave slide body and a convex slide body which are fixed to the structure and are arranged so as to be slidable relative to each other in a reciprocating manner; and a biasing means which pushes the slide bodies to each other. Each slide body has: a first slide surface having a shape which increases a height of the slide body mechanism 2 along with the increase of a displacement amount of the slide body in one sliding direction from a neutral position relative to the counterpart slide body; and a second slide surface having a shape by which the height of the slide body mechanism is increased along with the increase of the displacement of the slide body in the other sliding direction from the neutral position.

Abstract: Methods for the fabrication of nanostructures, including nanostructures comprised of carbon nanotubes, and the nanostructures, devices, and assemblies prepared by these methods, are described.