Abstract: A fiber optic dosimeter probe for sensing radiation dose including an optical fiber having a free end and a sensitive end, a window having a sensitive side and a rear side; a radiation sensitive layer between the sensitive end of the optical fiber and a sensitive side of the window, the radiation sensitive layer being made of a material having an optical property that changes with absorbed radiation dose, an amount of the material corresponding to a predetermined sensitivity to radiation; wherein the window and the optical fiber have a near water equivalent interaction with radiation and are MR compatible.
Type:
Grant
Filed:
July 6, 2011
Date of Patent:
April 7, 2015
Assignees:
Institut National D'Optique, University Health Network
Inventors:
Alexandra Rink, David Jaffray, Ozzy Mermut, Serge Caron, André Croteau, François Roy-Moisan
Abstract: A soft-start circuit composed of active components and passive components and a soft-start voltage regulator based on this soft-start circuit are disclosed. The soft-start voltage regulator is coupled to a generator, a battery and a starter. When the starter is started, the soft-start voltage regulator receives the voltage of the battery to generate a soft-start signal, enabling the generator to establish a voltage. Further, after the generator established the voltage, the soft-start voltage regulator is shut off and the soft-start signal is outputted.
Abstract: The present invention provides a positioning method for long-thin fleet, which moves along a direction and has a motion track and a leading member. The leading member is in forefront of the motion track. The positioning method comprises the following steps: a positioning step and a transmitting step. The positioning step gets a positioning data through a GPS in a preset time. The transmitting step transmits a periodic signal to the members of the fleet through a wireless network system. The leading member proceeds the positioning and transmitting steps. The motion track is connected according to the positioning data.
Abstract: Described herein are methods, uses, and pharmaceutical compositions for treating heart disease that include a bone morphogenetic protein (BMP). In addition, described herein are methods, uses, and compositions for preventing or slowing fibrosis in diseased or injured tissue, and/or for preventing or slowing cell death in diseased or injured tissue.
Type:
Grant
Filed:
March 30, 2010
Date of Patent:
April 7, 2015
Assignee:
Indiana University Research and Technology Corporation
Inventors:
Weinian Shou, Hanying Chen, Loren J. Field
Abstract: The present invention provides pyrazole derivative compounds and pharmaceutically acceptable salts thereof. The compounds of the present invention have an excellent effect of preventing and treating osteoporosis.
Type:
Grant
Filed:
November 6, 2013
Date of Patent:
April 7, 2015
Assignee:
Ewha University—Industry Collaboration Foundation
Inventors:
Yun Soo Bae, Jee Hyun Lee, Mi Sun Seo, Soo Young Lee, Sun Choi, Kee In Lee, Hye Rin Bin, Do Min Lee
Abstract: A 6H-indolo[2,3-b]quinoxaline derivative has a structure of formula (I). R9 is a member selected from the group consisted of an aryl group having one or more substituents and a heteroaryl group having one or more substituents, and R1 to R8 are substituents. The 6H-indolo[2,3-b]quinoxaline derivative of the present invention incorporates an indole and a quinoxaline group therefore inherits good energy transfer ability from indole and good electron-injection ability from quinoxaline. The compound of the present invention may function as a host material or a dopant in the light-emitting layer. In addition, the compound of the present invention may function as hole transport material, electron transport material, hole blocking material, electron blocking material, hole injecting material or electron injecting material.
Abstract: An embodiment of the invention is a technique to suppress noise in a jet engine. A substantially annular fan nozzle of a separate-flow turbofan engine includes a flow boundary surface and an outlet to discharge fan air into atmosphere. At least one vane extends substantially radially from the flow boundary surface to vector at least a portion of the fan air toward a direction where noise suppression is desired. The-vane is situated in proximity of the outlet and has a span substantially greater than a thickness of a local boundary layer of the fan air.
Type:
Grant
Filed:
January 10, 2007
Date of Patent:
April 7, 2015
Assignee:
The Regents of the University of California
Abstract: Methods of inhibiting one or more biological activities of Macrophage migration inhibitory factor (MIF) polypeptides are provided using an MIF inhibitory compound. The methods include therapeutic methods for treating cancers and inflammatory diseases.
Type:
Grant
Filed:
May 24, 2007
Date of Patent:
April 7, 2015
Assignee:
University of Louisville Research Foundation, Inc.
Inventors:
Robert A. Mitchell, John O. Trent, Jason B. Meier
Abstract: The invention provides an immunostimulatory peptide containing the amino acid sequence SAFFLFCSE and uses thereof. The invention also provides an immunostimulatory peptide containing the amino acid sequence DPNAPKRPPSAFFLX1X2X3X4 or derivatives thereof. In one embodiment, when X1 is alanine (A), glycine (G), or valine (V) then X2 is C, X3 is S and X4 is E; wherein when X2 is alanine (A), glycine (G), or valine (V) then X1 is F, X3 is S and X4 is E; wherein when X3 is alanine (A), glycine (G), or valine (V) then X1 is F, X2 is C and X4 is E; or wherein when X4 is alanine (A), glycine (G), or valine (V) then X1 is F, X2 is C and X3 is S.
Type:
Grant
Filed:
July 27, 2011
Date of Patent:
April 7, 2015
Assignee:
The Regents of the University of California
Abstract: Systems and methods for camera-based fingertip tracking are disclosed. One such method includes identifying at least one location of a fingertip in at least one of the video frames, and mapping the location to a user input based on the location of the fingertip relative to a virtual user input device.
Type:
Grant
Filed:
June 12, 2012
Date of Patent:
April 7, 2015
Assignee:
University of Central Florida Research Foundation, Inc.
Abstract: A generic model structure captures basic characteristics in BIS-based patients' responses to anesthesia and surgical stimulation, the model being used in combination with the insight of an anesthesiologist. The model structure represents the patient response with a time delay, a time constant for response speed, and a nonlinear function for drug sensitivity. Clinical data confirms the model structure and is used to establish parameters and function forms for individual patients. A feedback and predictive control strategy for anesthesia drug infusion is then introduced on the basis of the patient model. Feedback control alone cannot avoid large fluctuations in BIS values when significant surgical stimulation is imposed, as a result of time delays in a patient's response to drug infusion. Predictive control attenuates fluctuations of BIS levels from surgical stimulation.
Abstract: A method for forming a nano-textured surface on a substrate is disclosed. An illustrative embodiment of the present invention comprises dispensing of a nanoparticle ink of nanoparticles and solvent onto the surface of a substrate, distributing the ink to form substantially uniform, liquid nascent layer of the ink, and enabling the solvent to evaporate from the nanoparticle ink thereby inducing the nanoparticles to assemble into an texture layer. Methods in accordance with the present invention enable rapid formation of large-area substrates having a nano-textured surface. Embodiments of the present invention are well suited for texturing substrates using high-speed, large scale, roll-to-roll coating equipment, such as that used in office product, film coating, and flexible packaging applications. Further, embodiments of the present invention are well suited for use with rigid or flexible substrates.
Type:
Grant
Filed:
April 1, 2011
Date of Patent:
April 7, 2015
Assignee:
The Board of Trustees of the Leland Stanford Junior University
Abstract: A display includes one or more organic light emitting device panels. Each organic light emitting device panel has an array of single-color subpixel areas of different colors extending over an active area thereof arranged in a predetermined pattern by color. At least one of the subpixel areas in the predetermined pattern that would otherwise be designated as a subpixel area through which blue light is emitted based on a position thereof in the predetermined pattern being predetermined to be non-emissive. A volume of the organic light emitting device panel associated with the at least one predetermined non-emissive subpixel area is non-emissive and includes a via or a functional electronic component therein.
Abstract: A nut for a ball screw mainly includes a nut, multiple dual-narrowed paths, multiple micro fans, a control portion, and multiple temperature sensing portions. The nut has a threaded path and the dual-narrowed paths are defined through the central axis of the nut and substantially parallel to the threaded path. Each of the dual-narrowed paths has a high-speed area and the diameter of each of the dual-narrowed paths is gradually reduced from two ends toward the high-speed area. The nut has micro fans which drive the air flows and reduce the temperature to increase the life of use and the precision of positioning.
Abstract: An exemplary two-stroke internal combustion engine can comprise one or more cylinders comprising exhaust ports, one or more pistons configured to cyclically cover and uncover the exhaust ports during reciprocation of the pistons within the cylinders, and one or more rotary exhaust valves associated with each exhaust port. The exhaust valves can be configured to rotate around a valve axis that is substantially parallel to an axis of rotation of a crank shaft of the engine. Each exhaust valve at least partially obstructs the associated exhaust port during a portion of the exhaust valve's rotation about the valve axis while the associated exhaust port is at least partially uncovered by the associated piston, thereby trapping fresh charge within the combustion chamber.
Type:
Grant
Filed:
February 24, 2012
Date of Patent:
April 7, 2015
Assignee:
University of Idaho
Inventors:
Andrew Hooper, Coleman Bode, Alexander Fuhrman, Ty Lord
Abstract: A lift generating device is provided enabling vertical flight. The lift generating device includes a first revolution structure having a funnel shape and a second revolution structure having a funnel shape. Each revolution structure includes a circular open surface and an open stem. The second revolution structure is attached to the first revolution structure by a plurality of connectors so as to form a gap between the first revolution structure and the second revolution structure. A propeller is coupled to an open stem at a bottom end of the first revolution structure and a motor is operatively connected to the propeller to provide power for the propeller to suction air into the lift generating device.
Type:
Grant
Filed:
August 31, 2012
Date of Patent:
April 7, 2015
Assignee:
Embry-Riddle Aeronautical University, Inc.
Abstract: A switchable adhesion device combines two concepts: the surface tension force from a large number of small liquid bridges can be significant (capillarity-based adhesion) and these contacts can be quickly made or broken with electronic control (switchable). The device grabs or releases a substrate in a fraction of a second via a low voltage pulse that drives electroosmotic flow. Energy consumption is minimal since both the grabbed and released states are stable equilibria that persist with no energy added to the system. The device maintains the integrity of an array of hundreds to thousands of distinct interfaces during active reconfiguration from droplets to bridges and back, despite the natural tendency of the liquid towards coalescence. Strengths approaching those of permanent bonding adhesives are possible as feature size is scaled down. The device features compact size, no solid moving parts, and is made of common materials.
Abstract: A laryngoscope is provided with which an operator can directly observe the trachea inlet portion of a patient easily by safely and surely lifting the epiglottis of the patient with a proximal end portion of a laryngoscope blade which is inserted in the mouth of the patient. The blade is connected to a distal end portion of a grippable handle, a first electrode is mounted on a distal end portion of the blade, and a second electrode is configured to adhere to a skin surface of the patient in the vicinity of the epiglottis, and a low frequency current is supplied to flow between the first electrode and the second electrode.
Type:
Grant
Filed:
August 19, 2010
Date of Patent:
April 7, 2015
Assignee:
National University Corporation Okayama University
Abstract: Provided is a sensitizing detection agent of an oral or intravenous administration type which enables the detection of bladder cancer with a higher sensitivity without causing pain to the patient. A sensitizing detection agent for bladder cancer comprising 5-aminolevulinic acid (ALA), a derivative thereof, or a salt of these is orally or intravenously administered, and a video camera system is inserted via the urethra and a blue light at 380-440 nm is irradiated to observe the red fluorescent part. Further, VLD-M1 is inserted and a blue light at 405 nm is irradiated to observe fluorescence intensity (relative intensity) of the red light part. For oral administration, 20 mg/kg (maximum of 1 g) of ALA is dissolved in 50 mL of a 5% glucose solution prior to the administration.
Abstract: Provided herein are methods of determining the aggressiveness or indolence of a ductal carcinoma in situ lesion. Also provided are methods of developing treatment plans for subjects with a ductal carcinoma in situ lesion based on the aggressiveness of the lesion.