Abstract: Exemplary systems, methods, and computer-accessible mediums can be provided that can generate resultant data regarding fiber tract(s) and anatomical structure(s). For example, first information related to imaging data of the anatomical structure(s) can be received. Second information related to a predictive model of further fiber tract(s) can be received. The resultant data can be generated based on the first information, the second information and a fiber cost procedure.
Type:
Grant
Filed:
April 7, 2014
Date of Patent:
December 10, 2019
Assignees:
New York University, ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG
Inventors:
Dmitry S. Novikov, Valerij Kiselev, Marco Reisert
Abstract: Biological tissue such as skeletal and cardiac muscle can be imaged by using an objective-based probe in the tissue and scanning at a sufficiently fast rate to mitigate motion artifacts due to physiological motion. According to one example embodiment, such a probe is part of a system that is capable of reverse-direction high-resolution imaging without needing to stain or otherwise introduce a foreign element used to generate or otherwise increase the sensed light. The probe can include a light generator for generating light pulses that are directed towards structures located within the thick tissue. The system can additionally include aspects that lessen adverse image-quality degradation. Further, the system can additionally be constructed as a hand-held device.
Type:
Grant
Filed:
November 18, 2014
Date of Patent:
December 10, 2019
Assignee:
The Board of Trustees of the Leland Stanford Junior University
Inventors:
Gabriel Nestor Sanchez, Scott L. Delp, Mark J. Schnitzer, Michael E. Llewellyn
Abstract: This invention provides a method for decellularizing adipose tissue, comprising subjecting the adipose tissue to one or more incubations in an enzymatic digestion solution containing one or more enzymes, and one or more solvent extractions, wherein decellularized adipose tissue comprising an extracellular matrix with well-preserved three-dimensional structure is obtained. The invention also provides a decellularized adipose tissue comprising an extracellular matrix with well-preserved three-dimensional architecture, and bioscaffolds, microcarrier beads, and coatings comprising the decellularized adipose tissue.
Abstract: Unpredictable random numbers are used to provide the parameter values and seeds for a parameterized random number generator, thereby providing forensic reproducibility of a simulation. The values generated unpredictably to provide the parameters and seeds for the random number generator are stored so that the same random numbers can be utilized for a subsequent computation in the simulation.
Type:
Grant
Filed:
November 9, 2017
Date of Patent:
December 10, 2019
Assignee:
The Florida State University Research Foundation, Inc.
Abstract: The present invention relates to a wireless communication system. More specifically, as a method for transmitting data in a wireless communication system performing a CoMP operation by using a cache, a method for transmitting data, according to the present invention, can comprise the steps of: determining a transmission mode among a plurality of transmission modes on the basis of at least one piece of data stored in the cache; determining data to be transmitted in the transmission mode; and transmitting the data according to the determined transmission mode, wherein the transmission mode can comprise: a first mode for coordinately performing data transmission between coordinated base stations; a second mode for coordinately performing scheduling by sharing channel information between the coordinated base stations; and a third mode for combining the first mode and the second mode.
Type:
Grant
Filed:
November 10, 2015
Date of Patent:
December 10, 2019
Assignees:
LG ELECTRONICS INC., RESEARCH BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY, KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventors:
Woo Jin Kim, Hae Sol Lee, Dongin Kim, Wan Choi, Hanbyul Seo, Byounghoon Kim
Abstract: A magnetic antenna structure has a substrate (e.g., a flexible printed circuit board (PCB) carrier), a magneto-dielectric (MD) layer, and an antenna radiator. The MD layer increases electromagnetic (EM) energy radiation by lowering the EM energy concentrated on the antenna substrate. The resonant frequency and antenna gain of the magnetic antenna structure are generally lower and higher, respectively, relative to dielectric antennas of comparable size. Thus, the magnetic antenna structure provides better miniaturization and high performance with good conformability.
Type:
Grant
Filed:
April 28, 2014
Date of Patent:
December 10, 2019
Assignee:
The Board of Trustees of the University of Alabama for and on behalf of the University of Alabama
Abstract: Various embodiments of the present invention provide a conduit system including an outer lumen, an inner lumen, and an attaching device. In other embodiments, a multiple access port device adapted for communication with at least one of an outer lumen, an inner lumen, or an attaching device of a conduit system is provided. In yet other embodiments, a system including an inner lumen that is collapsible is provided. Means for closing a conduit system are also provided, including a plug for insertion through an attaching device and a variable radius coiled member associated with an attaching device.
Type:
Grant
Filed:
March 18, 2016
Date of Patent:
December 10, 2019
Assignees:
Emory University, Georgia Tech Research Corporation
Inventors:
Jorge H. Jimenez, Ajit P. Yoganathan, Seth West, Vinod Thourani
Abstract: A fusion chimeric protein is described herein that can assemble a functional carboxysome core, which is able to fix carbon by taking atmospheric carbon dioxide and converting it into useful carbon-containing compounds such as 3-phosphoglycerate (3-PGA).
Type:
Grant
Filed:
August 24, 2017
Date of Patent:
December 10, 2019
Assignee:
Board of Trustees of Michigan State University
Abstract: The present invention provides gene expression profiles indicative of whether a patient afflicted with PR driven malignancies is likely to be responsive to treatment with a therapeutic compound that is an anti-progestin. By identifying such responsiveness, a treatment provider may determine in advance those patients who would benefit from such treatment, as well as identify alternative therapies for non-responders. Also, provided are methods of using gene expression profiles and assays for identifying the presence of a gene expression profile in a patient.
Type:
Grant
Filed:
March 15, 2013
Date of Patent:
December 10, 2019
Assignee:
Regents of the University of Minnesota
Inventors:
Carol Ann Lange, Todd Philip Knutson, Jason Basil Nikas
Abstract: A method for treating a patient suffering from one of septic shock, acute kidney injury, severe hypotension, cardiac arrest, and refractory hypotension, but not from myocardial infarction, is provided. The method includes administering a therapeutically effective dose of Angiotensin II, or Ang II, to the patient.
Type:
Grant
Filed:
January 12, 2018
Date of Patent:
December 10, 2019
Assignee:
The George Washington University a Congressionally Chartered Not-for-Profit Corporation
Abstract: A device and method of generating an electrical potential including an electrochemical cell, and at least one heat source, cooling source or both. The electrochemical cell includes an anode and a cathode connected by a polymer electrolyte layer, preferably a dry polymer electrolyte layer. The heat source, if present, is placed in direct thermal contact with one of the anode or cathode, while the cooling source, if present, is placed in direct thermal contact with one of the anode or cathode not in contact with the heat source. The resulting temperature differential between the anode and cathode induces a concentration gradient between the anode and the cathode generating the electrical potential.
Type:
Grant
Filed:
August 15, 2017
Date of Patent:
December 10, 2019
Assignee:
THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
Abstract: Various methods and systems are provided for multifunctional denture systems. In one example, among others, a multifunctional oral prosthetic system includes an oral prosthetic device that may be located in an oral cavity. The oral prosthetic device includes a plurality of sensors and an internal module in communication with the plurality of sensors. The internal module is configured to provide sensor data corresponding to at least one of the plurality of sensors to an external processing unit when located in an oral cavity.
Type:
Grant
Filed:
September 27, 2012
Date of Patent:
December 10, 2019
Assignees:
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC., THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF BAIRD RESEARCH PARK
Inventors:
Yong-Kyu Yoon, Gloria J. Kim, Xiaoyu Cheng, Marc Campillo-Funollet, Carlos A. Munoz
Abstract: Methods for preventing, delaying the onset of, or treating rejection of an allograft using a DNA vaccine, where the vaccine can comprise a polynucleotide encoding a pro-apoptotic protein, like BAX and/or a polynucleotide encoding an autoantigen or donor antigen, like secreted glutamic acid decarboxylase 55. Administering one of the DNA vaccines to a transplant recipient, as described herein, can induce a donor specific tolerogenic response.
Abstract: Methods of extracting biodiesel from a mixture of biodiesel and alcohol are provided. The methods can include contacting the mixture of biodiesel and alcohol with a petrodiesel to form a two-phase system including a polar phase and a nonpolar phase, wherein the alcohol preferentially partitions into the polar phase and the petrodiesel and biodiesel preferentially partition into the nonpolar phase, and separating the nonpolar phase from the polar phase to extract the biodiesel. The methods can include using a multi-stage extraction apparatus, for example in countercurrent or crosscurrent extraction arrangement. Methods of making a biodiesel blend are also provided. The methods can include making a biodiesel blend with a biodiesel content from about B2 to about B25.
Abstract: Described are N-(6-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-2-yl)-2,3-dihydro-1H-inden-1-yl)benzamide and acetamide-containing compounds that inhibit WDR5 and associated protein-protein interactions, pharmaceutical compositions including the compounds, and methods of using the compounds and compositions for treating disorders and conditions in a subject.
Type:
Grant
Filed:
September 19, 2018
Date of Patent:
December 10, 2019
Assignee:
Vanderbilt University
Inventors:
Stephen W. Fesik, Shaun R. Stauffer, James M. Salovich, William P. Tansey, Feng Wang, Jason Phan, Edward T. Olejniczak
Abstract: Provided are a super water repellent polymer hierarchical structure, a heat exchanger having super water repellency, and a manufacturing method thereof A super water repellent polymer hierarchical structure can be simply and repeatedly manufactured by using only a method for utilizing a super water repellent hierarchical structure and mechanically molding a polymer material thereon. In addition, a heat exchanger having super water repellency can be provided by providing super water repellency on the fin surface of a heat exchanger by using a dip method and vacuum drying.
Type:
Grant
Filed:
July 22, 2015
Date of Patent:
December 10, 2019
Assignee:
Industry-University Cooperation Foundation Hanyang University
Inventors:
Dong Rip Kim, Kwan-Soo Lee, Youngjun Cho, Hanmin Jang, Heung Soo Lee
Abstract: A quantization device includes: a trellis-structured vector quantizer which quantizes a first error vector between an N-dimensional (here, “N” is two or more) subvector and a first predictive vector; and an inter-frame predictor which generates a first predictive vector from the quantized N-dimensional subvector, wherein the inter-frame predictor uses a predictive coefficient comprising an N×N matrix and performs an inter-frame prediction using the quantized N-dimensional subvector of a previous stage.
Type:
Grant
Filed:
May 7, 2015
Date of Patent:
December 10, 2019
Assignees:
SAMSUNG ELECTRONICS CO., LTD., INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS
Inventors:
Ho-sang Sung, Sang-won Kang, Jong-hyun Kim, Eun-mi Oh
Abstract: Compositions of, methods of making, and methods of using hybrid nanoparticles comprise at least one semiconducting polymer and at least one nonsemiconducting polymer. Compositions of, methods of making and methods of using hybrid nanoparticles comprise at least one semiconducting polymer and non-semiconducting polymers wherein the non-semiconducting polymer comprises more than one non-semiconducting polymer such that at least one non-semiconducting polymer is functionalized for bioconjugation. The hybrid nanoparticles are polarization-sensitive and have low mass ratios with large fluorescence.
Type:
Grant
Filed:
July 8, 2014
Date of Patent:
December 10, 2019
Assignee:
University of Washington Through Its Center For Commercialization
Abstract: Compositions comprising an alginate, a source of sodium ions and a carrier (e.g., a pharmaceutically acceptable carrier), which are characterized by reduced association of the alginate chains and hence by at least one of: (i) a zeta potential weaker than ?25 mV, at a concentration of 0.5% (w/v) alginate in the carrier; and (ii) a diffusion coefficient of at least 10?8 cm2/second, at a concentration of 0.5% (w/v) alginate in the carrier, are disclosed. Also disclosed are uses of the composition and methods utilizing the composition for treating inflammatory bowel disease; liver damage, diseases and disorders, for treating a medical condition treatable by a hepatotoxic agent and for reducing or preventing liver damage, including liver damage caused by a hepatotoxic agent.
Type:
Grant
Filed:
December 30, 2013
Date of Patent:
December 10, 2019
Assignees:
Hadasit Medical Research Services and Development Ltd., B.G. Negev Technologies & Applications Ltd., at Ben-Gurion University
Inventors:
Smadar Cohen, Yaron Ilan, Eyal Shteyer, Ami Ben-Ya'Acov
Abstract: Embodiments include an image acquisition circuit configured to access an image of a region of tissue demonstrating cancerous pathology, a nuclei detection and graphing circuit configured to detect cellular nuclei represented in the image; and construct a nuclear sub-graph based on the detected cellular nuclei, where a node of the sub-graph is a nuclear centroid of a cellular nucleus; a cell run length (CRF) circuit configured to compute a CRF vector based on the sub-graph; compute a set of CRF features based on the CRF vector and the sub-graph; and generate a CRF signature based, at least in part, on the set of CRF features; and a classification circuit configured to compute a probability that the region of tissue will experience cancer progression, based, at least in part, on the CRF signature; and generate a classification of the region of tissue as a progressor or non-progressor.