Abstract: Compositions, systems, and methods for preparation of polypeptides having multiple iterations of non-standard amino acids are provided. The compositions and method can be used to produce recombinant proteins at a greater yield than the same or similar polypeptides made using conventional compositions, systems, and methods. Accordingly, in some embodiments, the polypeptides are ones that could not be made using conventional methods and reagents, or could not be made a sufficient yield or purity to serve a practical purpose using conventional methods and reagents. Polypeptides made using the disclosed compositions, systems, and methods are also provided.

Abstract: Provided is a ureteral stent (=50) including a bladder portion (=52) positioned in a bladder of a patient, a kidney portion (=54) positioned in a kidney and ureteral passageway of the patient, and one or more tethers (=56) coupling the bladder portion to the kidney portion. The ureteral stent allows urine to pass around a blockage, and allows a ureter orifice connecting the ureteral passageway to the bladder to move between a compressed state and an uncompressed state to prevent or minimize urinary reflux, flank pain, blood in the urine, etc., while allowing the bladder portion to move freely in the bladder to prevent the bladder portion from irritating the trigone muscle.

Abstract: Disclosed is a thermostable DNA polymerase preparation which can illimitably reduce the risk of false positivity in the detection of a subject microorganism utilizing a gene amplification reaction and therefore enables the selective amplification of DNA for detecting the subject microorganism even when the amount of the subject microorganism is small and therefore the amount of DNA collected therefrom is extremely small, and can be produced at a reduced cost. Also disclosed is a method for quantifying or quantifying/identifying a subject organism to be detected rapidly, conveniently and with high sensitivity using the preparation of the present invention.

Abstract: The present disclosure encompasses antibacterial compositions and methods of treating bacterial infections caused by resistant bacteria.

Abstract: Provided is a cancer cell growth inhibition and killing device using a blue light LED. The present invention comprises: a bed part which has a top plate on which the body is laid to stand by; a main body part provided with a treatment space, which has a predetermined size and on which the bed part is disposed, and having a chamber which is divided by the treatment space and a transparent plate formed of a light-transmitting material to thus form a treatment light generation space; and a treatment light generation unit which generates a treatment light having a wavelength band of a predetermined size when power is applied so that the treatment light can penetrate the subcutaneous tissue of the body and thereby stimulate and kill cancer cells moving along blood vessels, and which is provided in the chamber so as to irradiate the treatment space with the treatment light after the treatment light has penetrated though the transparent plate.

Abstract: Provided is random access method, performed by terminal for uplink data transmission during random access process between cellular based machine communication terminal and base station. The method includes performing random access process between cellular based machine communication terminal and base station, and the random access process includes selecting random access resource by considering coverage level and whether to support multi-tone transmission or not.

Abstract: A thiazole derivative compound includes a compound having the following structural formula: or a pharmaceutically acceptable salt thereof.

Abstract: The present invention discloses a core-shell structure supported tungsten composite catalyst and a preparation method and use thereof. Most of the existing synthesis methods of the main ring of quinolone drugs have the defects of many synthesis steps, cumbersome operation, large amount of three wastes, higher costs and the like. The present invention prepares a magnetic separable core-shell supported tungsten composite catalyst, WO3/SiO2/Fe3O4, by preparing Fe3O4 colloid and SiO2/Fe3O4 composite nano-particles. This magnetic separable core-shell supported tungsten composite catalyst, WO3/SiO2/Fe3O4, is used to catalyze and synthesize quinolone compounds. The present invention provides an efficient preparation method of quinolone compounds using a catalyst which can be recovered by magnetic separation and recycled.

Abstract: Systems and methods for using positions of detected, real object boundaries to enable user interaction with a virtual object are disclosed. A system can include one or more sensors or trackers configured to detect boundaries of a transparent, real object within a three-dimensional coordinate system. A computing device configured to track positions of the detected boundaries of the real object within the three-dimensional coordinate system. The computing device may also track a position of a virtual object within the three-dimensional coordinate system. The computing device may determine whether the position of the virtual object is within the positions of the detected boundaries of the real object. The computing device may also enable user interaction with the virtual object via user interface and receive input for interacting with the virtual object in response to determining that the position of the virtual object is within the positions of the detected boundaries.

Abstract: A method for analyzing an image of a lesion on the skin of a subject including (a) identifying the lesion in the image by differentiating the lesion from the skin; (b) segmenting the image; and (c) selecting a feature of the image and comparing the selected feature to a library of predetermined parameters of the feature. The feature of the lesion belongs to any one selected from the group: color, border, asymmetry and texture of the image.

Abstract: A membrane-based assembly and process for cooling and/or de-vaporizing a gas. The assembly and process can provide sensible cooling and/or dehumidification of air, and can be contained within a single, integrated apparatus.

Abstract: The present invention is directed to EGFR-specific peptide reagents, methods for detecting pre-cancer, early cancer and/or cancer using the peptide reagents, and methods for targeting pre-cancer cells, early cancer cells and/or cancer cells using the peptide reagents. In one aspect, the disclosure provides reagents consisting essentially of a peptide QRHKPRE (SEQ ID NO: 1), HAHRSWS (SEQ ID NO: 2), YLTMPTP (SEQ ID NO: 3), TYPISFM (SEQ ID NO: 4), KLPGWSG (SEQ ID NO: 5), IQSPHFF (SEQ ID NO: 6), YSIPKSS (SEQ ID NO: 7), SHRNRPRNTQPS (SEQ ID NO: 8), NRHKPREKTFTD (SEQ ID NO: 9).

Abstract: Prostate-specific membrane antigen (PSMA) binding compounds having radioisotope substituents are described, as well as chemical precursors thereof. Compounds include pyridine containing compounds, compounds having phenylhydrazine structures, and acylated lysine compounds. The compounds allow ready incorporation of radionuclides for single photon emission computed tomography (SPECT) and positron emission tomography (PET) for imaging, for example, prostate cancer cells and angiogenesis.

Abstract: The disclosure relates to a method for creating a nanoscale structure. The method includes forming a window in a semiconductor structure, the semiconductor structure comprising a substrate, a first semiconductor layer, and a mask layer; depositing a second semiconductor layer within the window such that a gap remains between the second semiconductor and a portion of the window; and regrowing the first semiconductor layer such that the first semiconductor layer fills the gap.

Abstract: Small molecule covalent inhibitors of DCN1 and compositions containing the same are disclosed. Methods of using the DCN1 covalent inhibitors in the treatment of diseases and conditions wherein inhibition of DCN1 provides a benefit, like oxidative stress-related diseases and conditions, neurodegenerative diseases and conditions, metabolic disorders, and muscular nerve degeneration, also are disclosed.

Abstract: A method of exchanging fluids with suspended particles includes providing a microfluidic device with a first inlet channel operatively coupled to a source of particles and a second inlet channel operatively coupled to an exchange fluid. A transfer channel is connected at a proximal end to the first inlet channel and the second inlet channel. First and second outlet channels are connected to a distal end of the transfer channel. The source of particles is flowed at a first flow rate into the first inlet channel while the exchange fluid is flowed at a second flow rate into the second inlet channel wherein the ratio of the second flow rate to the first flow rate is at least 1.5. Particles are collected in one of the first and second outlet channels while fluid substantially free of particles is collected in the other of the first and second outlet channels.

Abstract: A system of topographic patterns for the prevention of bacterial adhesion and biofilm formation. The patterns may be provided on the surfaces of certain devices that are prone to bacterial adhesion and biofilm formation, such as urinary catheters. To reduce bacterial adhesion and biofilm formation, and to remove existing biofilms, the patterns are induced to transform from a first topography to a second topography. For example, the surface patterns may be formed from a shape memory polymer and then heated to transform the patterns from the first topography to the second topography to dislodge bacteria and prevent fouling.

Abstract: An ice-skating measuring apparatus includes an ice-skate blade holder and an ice-skate blade. The blade holder has a front beam column and a rear beam column. The blade includes at least one sensor configured to measure forces acting on the blade, and the blade is detachable from the blade holder.

Abstract: A method for accurately producing the drilled hole in a wall of a component fabricated by investment casting process, such as for use in a blade or steam turbine includes the following steps. The 3D data of actual component is obtained from the measurements or from the numerical simulation. The actual model and the ideal model are aligned and compared, a series of cutting planes are given to establish a series of 2D cross-sections of the actual and ideal models after registration. Each cross-section is dispersed into discrete points, the distance between each corresponding points are calculated and formed into 2D displacement. The accurate parametric model consisting of the depth, hole center, and the nominal vector is obtained on the basis of considering the deviations in geometrical and positional values. The drilled hole is then produced according to the corrected parametric drilled-hole geometrical and positional value.

Abstract: Description and specification of a new and distinct nectarine tree cultivar named ‘Effie’ which originated from a hand-pollinated cross of Ark. 720 nectarine (female; non-patented) x Ark. 747 peach (male; non-patented) made in 2004. This new nectarine cultivar can be distinguished by its firm fruit with non-melting white flesh, late ripening season, medium size, attractive appearance, high red skin color, excellent fruit quality, good flavor, and resistance to bacterial spot disease.