Abstract: The present invention belongs to the field of optical detection devices, and specifically discloses a polarization modulator and a polarization measurement system, comprising a rotating compensator and a polarizer, in which the rotating compensator is a continuously rotating composite waveplate, the composite waveplate is composed of a plurality of single-waveplates of the same material, and the overall structure of the composite waveplate is determined by thicknesses and fast axis intersection angles of the respective single-waveplates according to the optimization design of the polarization characteristic transfer matrix of the polarization modulator. The polarization modulator of the invention has the advantages of simple structure, easy processing and a wide applicable wavelength range, and a wide-waveband polarization measurement system can be designed based on the polarization modulator, which is adapted to the requirements of wide-waveband precision polarization measurement.

Abstract: An anti-inflammatory drug containing a G0/G1 switch 2 (G0S2) inhibitor as an active ingredient is useful as a novel anti-inflammatory drug.

Abstract: A method for manufacturing a gas sensor may be provided, the method comprising the steps of: preparing a porous base substrate; providing, on the porous base substarte, a source solution having graphene dispersed in a base solvent; manufacturing a graphene-impregnated base substrate by means of a driving process; and forming a first electrode and a second electrode on the graphene-impregnated base substrate.

Abstract: This disclosure describes compositions and methods for enhanced production of enduracidin in genetically engineered strains of Streptomycesfungicidicus. In particular, the present disclosure describes the genetic manipulation of regulatory genes orf24 and orf18 associated with the enduracidin (enramycin) biosynthesis gene cluster from Streptomyces fungicidicus to generate vector constructs and recombinant strains producing greater yields of enduracidin.

Abstract: A method of image projection including selecting a set of desired chromaticity coordinates of a projection system, the projection system including a plurality of laser sources; determining a set of parameters of an expected operational environment; and configuring each laser source to have a power ratio and a power spectrum density function generating a normalized power spectrum density function of the projection system having the set of desired chromaticity coordinates and a wavelength diversity factor of at least 2 in the expected operational environment. A projection system including an input device configured to receive a set of desired chromaticity coordinates and a set of operational parameters; a plurality of laser sources each having a power ratio and a power spectrum density function configured to generate a normalized power spectrum density function producing the set of desired chromaticity coordinates and a wavelength diversity factor of at least 2.

Abstract: The present invention relates to a medicament for preventing and/or treating cognitive impairment and/or a neurodegenerative disease with accumulation of a prionoid, comprising a Sendai virus envelope as an active ingredient and combined application of the medicament and an immune checkpoint inhibitor.

Abstract: The method for detoxifying asbestos disclosed here includes: preparing an asbestos-containing substance that contains at least one type of asbestos; preparing an asbestos treatment agent that contains a mineral acid, N-methyl-2-pyrrolidone and a fluoride; and bringing the asbestos-containing substance into contact with the asbestos treatment agent so as to detoxify asbestos in the asbestos-containing substance. Due to this configuration, asbestos in the asbestos-containing substance can be favorably detoxified.

Abstract: The present invention relates to a method, an apparatus, and a computer-readable medium for providing a chat device through a tactile interface device connected to the computing device to interact with a user, and more particularly, the chat module includes: an account management module for managing a user account of a user; a chat partner management module for managing one or more chat partners registered in the user account; a chat room management module for managing a chat room where the registered one or more chat partners are present; a chat conducting module for conducting a chat with chat room participants including the one or more chat partners in the chat room; and a tactile user interface (TUI) module for converting display data displayed on a screen of the computing device into an output signal for implementing a tactile screen of the tactile interface device.

Abstract: A vertical cavity light-emitting element comprises a substrate, a first multilayer reflector formed on the substrate, a semiconductor structure layer formed on the first multilayer reflector and including a light emitting layer, a second multilayer reflector formed on the semiconductor structure layer and constituting a resonator together with the first multilayer reflector, and a light guide layer configured to form a light guide structure including a center region extending in a direction perpendicular to the upper surface of said substrate between the first and second multilayer reflectors and including a light emission center of the light-emitting layer and a peripheral region provided around the center region and having a smaller optical distance between the first and second multilayer reflectors than that in the center region. The second multilayer reflector has a flatness property over the center region and the peripheral region.

Abstract: A structure used in the formation of a spintronics element, the spintronics element to include a plurality of laminated layers, includes a substrate, a plurality of laminated layers formed on the substrate, an uppermost layer of the plurality of laminated layers being a non-magnetic layer containing oxygen, and a protection layer directly formed on the uppermost layer, the protection layer preventing alteration of characteristics of the uppermost layer while exposed in an atmosphere including H2O, a partial pressure of H2O in the atmosphere being equal to or larger than 10?4 Pa, no other layer being directly formed on the protection layer.

Abstract: A method for utilizing a jamming-resistant receiver (JrRx) device includes receiving, by a BJM engine, a plurality of individual subcarrier signals that comprises separate signal portions of a combined signal stream, wherein the combined signal stream is a combination formed by a source signal stream from a sender device and one or more interfering jamming signals from a plurality of unknown jammer devices and computing, by the BJM engine, a respective plurality of BJM filters for the plurality of individual subcarrier signals in the absence of channel information corresponding to the interfering jamming signals.

Abstract: Disclosed are methods, pharmaceutical compositions, kits, and systems for treating or preventing cardiotoxicity in a subject undergoing treatment with an anthracycline chemotherapeutic agent. The methods, pharmaceutical compositions, kits, and systems typically include or utilize an agonist of the retinoic acid receptor gamma (RARG).

Abstract: Immunosensors according to present embodiments combine a sandwich bioassay with an electro-active, integrated optical waveguide (EA-IOW) for the detection of infectious pathogens and other analytes from a sample, whereby the electro-active waveguide surface is functionalized with a capture antibody capable of specific binding with a particular antigen. This functionalized arrangement then promotes the binding of a secondary, labeled antibody serving as a redox probe, which produces an analytical signal having unique spectral and electrochemical properties for the detection of virus antigens, pathogens, and other analytes that bind to proteins.

Abstract: The technical result of the invention is to simplify the technology of obtaining insulin-producing cells, obtaining at least 70% of functionally active insulin-producing cells in cell culture, that underwent differentiation. The method comprises obtaining epithelial progenitor cells and their subsequent differentiation into pancreatic cells, capable to glucose-sensitive insulin secretion in which pancreatic differentiation is performed in two stages: (a) at the first stage cells are differentiated within 4-15 days in a culture medium containing at least serum of a mammal, glutamine, epidermal growth factor, transferrin, sodium selenite, retinoic acid, isoproterenol; (b) at the second stage, cells are differentiated within 4-15 days in a culture medium containing at least serum of a mammal, glutamine, epidermal growth factor, retinoic acid, nicotinamide, hepatocyte growth factor, dexamethasone; moreover, the cultivation in both stages is carried out in gas atmosphere of 5% CO2 at 37° C.

Abstract: An encryption method is provided. According to the encryption method, a scaling factor may be reflected in a message and then, a homomorphic ciphertext may be generated using a public key. The generated ciphertext is, when decryption is performed, generated in a form that a result value obtained by adding an error value to a value obtained by reflecting the scaling factor in the message is restored. Accordingly, a homomorphic ciphertext capable of being computed in a ciphertext state can be effectively generated.

Abstract: A combination of three well-known and FDA approved compounds has been discovered to significantly suppress the proliferation of pancreatic cancer cells in clinically relevant models of pancreatic cancer. Embodiments of the invention include compositions of matter comprising a combination of agents such as metformin, simvastatin, and digoxin as well as methods of treating cancers using such agents. Illustrative methods include combining a population of pancreatic cancer cells with amounts of metformin, simvastatin, and digoxin sufficient to inhibit expression of BIRC5 protein in the population of pancreatic cancer cells, thereby inhibiting the growth of the population of pancreatic cancer cells.

Abstract: A protein kinase that includes a donor molecule and an acceptor molecule, methods of making the protein kinase, and methods of using the protein kinase are described. Measurement of the conformation of the kinase can be obtained using intramolecular FRET. The protein kinase can be used to, for example, identify conformational changes involved in kinase regulation, that is, as an allostery sensor; to identify kinase-binding molecules including, for example, kinase inhibitors; to identify cancer therapeutics; or for high-throughput screening.

Abstract: An optical pulse measuring method measuring an optical pulse generated from a pulse light source is provided. The method includes: splitting the optical pulse and then focusing them at a measuring point, so as to generate gas plasma by the autocorrelation of the split optical pulses; receiving the sound signal from the gas plasma and generate a plasma sound signal; and using the plasma sound signal to calculate the characteristics of the optical pulse. A measuring device is also provided.

Abstract: The presently disclosed subject matter is directed to dual specificity mitogen-activated protein kinase phosphatase (DUSP-MKP) inhibitors that sensitize cancer cells immune cell killing and methods of using the disclosed DUSP-MKP inhibitors for the treatment of cancer.

Abstract: There is provided a glaucoma surgery visualization apparatus. The apparatus has a goniolens which is rotationally coupled to a novel scleral retention device. The apparatus allows for viewing of the irido-corneal angle structures of the eye and related surgical procedures. The scleral retention device uses vacuum to temporarily adhere the apparatus to the sclera. Surgical apertures allow for surgical access, while the goniolens can rotate within the scleral retention device to facilitate proper viewing of the irido-corneal angle structures before, during and after surgery. An optional light source serves to illuminate the field of viewing to further assist the surgeon during various procedures that involve the glaucoma surgery visualization apparatus.