Abstract: A light emitting diode includes a first semiconductor layer, an active layer, a second semiconductor layer, an upper electrode, and a lower electrode. The active layer is sandwiched between the first semiconductor layer and the second semiconductor layer. The lower electrode is electrical connected with the first semiconductor layer, and the upper electrode is electrical connected with the second semiconductor layer. A surface of the second semiconductor layer away from the active layer is used as the light extraction surface. A surface of the first semiconductor layer connected with the lower electrode is a patterned surface comprising a plurality of grooves.

Abstract: A method for analyzing a fluid containing one or more analytes of interest includes; measuring a plurality of properties of a sample fluid with unknown concentrations of the one or more analytes of interest; and using the measurements and a model of the relationship between the plurality of properties and concentrations of the one or more analytes to calculate the concentration of at least one of the analytes of interest. The model may be an artificial neural network. The method may be used to monitor the concentration of inhibitors of gas hydrate formation in a fluid. Apparatus for use in the method is also provided.

Abstract: Composites comprising a continuous matrix formed from compounds having a rock salt structure (represented by the structure “MQ”) and inclusions comprising chalcogenide compounds having a rock salt structure (represented by the structure “AB”) are provided. Composites having the structure MQ-ABC2, where MQ represents a matrix material and ABC2 represents inclusions comprising a chalcogenide dispersed in the matrix material are also provided.

Abstract: An exemplary methodology, procedure, system, method and computer-accessible medium can be provided for authenticating a portion of a non-digital medium for a document, by receiving at least one image of at least one first marked portion of the non-digital medium for the document, extracting at least one first speckle pattern of the at least one first marked portion, and comparing the first speckle pattern of the at least one first marked portion with at least one second speckle pattern relating to the non-digital medium to determine if a similarity between the first and second speckle patterns equals or exceeds a predetermined amount.

Abstract: A method of forming an injectable radioactive composition, the method comprising the steps of: (a) depositing a solid form of technetium onto a carbon crucible; (b) preheating the solid form of technetium to remove any carrier; (c) plasma ablating the technetium and portions of the carbon crucible; (d) allowing the carbon and technetium metal to co-condense from the gas phase to produce a nanoparticle composite aerosol in an inert gas; (e) dispersing the nanoparticle composite in water containing a low concentration of surfactant using an electrostatic precipitator; (f) size fractionating the nanoparticle dispersion by filtration with hydrophilic membranes of known pore size.

Abstract: The invention provides compositions and method for delivering a therapeutic or diagnostic agent to a disease site in a mammal, the method comprising administering to the mammal a therapeutically or diagnostically effective amount of a pharmaceutical composition, wherein the pharmaceutical composition comprises the therapeutic or diagnostic agent coupled to a Procaspase 8 polypeptide and a pharmaceutically acceptable carrier.

Abstract: A system for performing anastomosis includes a plurality of staples, an annular staple support having structure for holding the staples, and a staple closing device for closing the staples to secure the canal ends together. A method for performing anastomosis and staples for performing anastomosis are also disclosed.

Abstract: An object is to provide a micro plate treating device and micro plate treating method capable of handling a larger number of kinds of solution or suspensions or a larger volume of solutions or suspensions per work area by use of a normalized micro plate without enlarging the scale of the device.

Abstract: An apparatus is disclosed. In some embodiments, the apparatus comprises an endoscope comprising a first distal end portion, and a tube comprising a second distal end portion, wherein the endoscope and the tube are in a side-by-side relationship and are coupled at distal end portions of the endoscope and the tube using a single coupling device.

Abstract: Disclosed are peptides having a cystine knot structural motif and comprising a sequence engineered for specificity against ?IIb?3 integrin, found on platelets, and a method of using the same in anti-thrombotic therapies. The present peptides utilize a cystine knot scaffold derived from modified agouti-related protein or agatoxin, An alternate library screening strategy was used to isolate variants of peptides that selectively bound to ?IIb?3 integrin or to both ?IIb?3 and ?V?3 integrins. Unique consensus sequences were identified within the identified peptides suggesting alternative molecular recognition events that dictate different integrin binding specificities. In addition, the engineered peptides prevented human platelet aggregation in a plasma-based assay and showed high binding affinity for ?IIb?3 integrin.

Abstract: In general, a computer-implemented method is described for receiving one or more requests to generate a medical study, retrieving from one or more data repositories one or more medical study instruments, receiving a selection of a particular medical study instrument to use in the medical study, generating by one or more computers a list of one or more research collaborators invited to review the medical study, and generating by one or more computers a list of one of more participants invited to join the medical study. Additionally, the computer-implemented method generates by one or more computer systems a data filter to format medical data from a first data format to a second data format, wherein the second data format complies with a third data format associated with one or more medical study instruments.

Abstract: The invention relates to a periodic signal processing method, a periodic signal conversion method, and a periodic signal processing device capable of reducing the influence of periodicity without using a spectral model. Time windows are arranged such that a center of each of the time windows is at a division position which divides a fundamental frequency in a temporal direction into fractions 1/n (where n is an integer equal to or larger than 2) so as to extract a plurality of portions of different ranges from a signal having periodicity. A power spectrum for the plurality of portions extracted by the respective time windows is calculated, and the calculated power spectrum is added with a same ratio.

Abstract: Disclosed is a fluid sampling device comprising a plurality of inlet channels, each of which is arranged to receive an airflow from an associated direction, such that a sampling medium associated with a particular inlet channel is exposed to airflow from the associated direction.

Abstract: Present embodiments are directed to features for maintaining or providing a beach area that is adjacent a water feature and that includes beach surface material disposed in one or more containment structures such that a multi-colored or illuminated beach surface is provided. Present embodiments may include multiple containment structures arrayed in an area adjacent a water feature, wherein each containment structure holds beach surface material of a different color. Further, present embodiments may include creating and/or distributing iridescent and/or phosphorescent beach surface material in one or more containment structures that define the beach area. Additionally, present embodiments may include adjustable or attachable barrier extensions to facilitate maintenance. Further, present embodiments may include transparent or translucent beach surface material disposed in one or more containment structures and a lighting system under the beach surface materials.

Abstract: This invention relates to an orally administrable, gastroretentive pharmaceutical dosage form which contains at least one pharmaceutically active ingredient and at least one polymeric adjuvant. The adjuvant serves to retain the dosage form in a selected region of the gastrointestinal tract for sufficient time for the pharmaceutically active ingredient to be released and absorbed. Ideally the dosage form will contain two or more pharmaceutically active ingredients which are delivered to different regions of the gastrointestinal tract.

Abstract: The invention provides compositions, methods, and kits diagnosing, monitoring, and otherwise characterizing a myopathy and for detecting the presence of autoantibodies in a biological sample.

Abstract: Use of compounds disclosed herein, typically progesterone or analog or derivative thereof, in the treatment of central nervous system cancers, specifically neuroblastoma and glioblastoma is provided. The treatment offers a reduced toxicity as compared to the currently available chemotherapeutic agents. The progesterone may be administered alone or in combination with, or in conjunction with other therapeutic agents.

Abstract: The present invention concerns compounds and their use to treat cell proliferative diseases such as cancer. Compounds of the present invention display significant potency as inhibitors of Jak2/STAT3 pathways and downstream targets and inhibit the growth and survival of cancerous cell lines.

Abstract: The present invention provided a method for salting-out extraction of acetone and butanol from a fermentation broth, characterized in that one type, or two or more types of salts and one type, or two or more types of extractants are added to an acetone-butanol-ethanol (ABE) fermentation broth, in which the salt saturation achieves 10%˜100%; and the volume ratio of the fermentation broth containing salts to the extractants is 1:0.1˜1:5. The mixture is allowed to stand until phase separation is formed. The top phase is a solvent phase or extraction phase enriched with acetone and butanol whereas the bottom phase is a salt-enriched phase or raffinate phase. This method involves many advantages, such as the simplified operation procedure, accelerated separation process and low separation cost, and therefore becomes a promising method of separating acetone and butanol in industrial application.

Abstract: Interconnected, open-celled porous or microporous polymeric foams are used for the preparation of heat transfer devices. The use of such porous polymeric foams can generate a turbulent flow within a heat exchanging liquid, thus enabling increased heat transfer to and from the fluid. The present disclosure provides devices having a heat transfer element containing a heat exchange region wherein a heat exchange fluid can be circulated through a porous polymeric foam; and method for making and using such devices.