Patents Assigned to University
  • NOTCH INDUCED NATURAL KILLER CELL GENERATION AND THERAPEUTIC USES
    Publication number: 20140186319
    Abstract: A method of preparing differentiated NK cells by ex vivo expansion includes the steps of; (1) isolating a plurality of CD34+ hematopoietic cells; (2) culturing the cells in a medium, wherein the medium includes an effective amount of a notch ligand and one or more cytokines selected from the group consisting of IL-7, IL-15, SCF, Flt-3, IL-3 and IL-6; and (3) maintaining the cells in culture for a duration of time sufficient to produce NK cells.
    Type: Application
    Filed: July 26, 2013
    Publication date: July 3, 2014
    Applicant: Case Western Reserve University
    Inventor: Rose C. Beck
  • MISCUT SEMIPOLAR OPTOELECTRONIC DEVICE
    Publication number: 20140183579
    Abstract: A method for improved growth of a semipolar (Al,In,Ga,B)N semiconductor thin film using an intentionally miscut substrate. Specifically, the method comprises intentionally miscutting a substrate, loading a substrate into a reactor, heating the substrate under a flow of nitrogen and/or hydrogen and/or ammonia, depositing an InxGa1-xN nucleation layer on the heated substrate, depositing a semipolar nitride semiconductor thin film on the InxGa1-xN nucleation layer, and cooling the substrate under a nitrogen overpressure.
    Type: Application
    Filed: January 2, 2013
    Publication date: July 3, 2014
    Applicants: Japan Science and Technology Agency, The Regents of the University of California
    Inventors: John F. Kaeding, Dong-Seon Lee, Michael Iza, Troy J. Baker, Hitoshi Sato, Benjamin A. Haskell, James S. Speck, Steven P. DenBaars, Shuji Nakamura
  • TREATMENTS FOR DIABETES MELLITUS AND OBESITY
    Publication number: 20140187619
    Abstract: Methods of treatment in subjects suffering from diabetes mellitus or obesity are provided. The methods comprise the step of administering an active agent directly to the small intestine in the subject. In particular, the active agent may be administered directly to the duodenum in the subject. The active agents useful in the treatments described herein include analgesic agents and, in particular, antinociceptive agents such as capsaicin, resiniferatoxin, and their analogues.
    Type: Application
    Filed: July 18, 2012
    Publication date: July 3, 2014
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Pankaj Jay Pasricha, Liansheng Liu
  • ECG Artifact Reduction System
    Publication number: 20140187975
    Abstract: An ECG signal processing system which removes the CPR-induced artifact from measured ECG signals obtained during the administration of CPR.
    Type: Application
    Filed: March 4, 2014
    Publication date: July 3, 2014
    Applicant: Johns Hopkins University
    Inventors: Henry R. Halperin, Ronald D. Berger
  • CERAMIC-CERAMIC COMPOSITES AND PROCESS THEREFOR, NUCLEAR FUELS FORMED THEREBY, AND NUCLEAR REACTOR SYSTEMS AND PROCESSES OPERATED THEREWITH
    Publication number: 20140183765
    Abstract: A process of producing ceramic-ceramic composites, including but not limited to nuclear fuels, and composites capable of exhibiting increased thermal conductivities. The process includes milling a first ceramic material to produce a powder of spheroidized particles of the first ceramic material, and then co-milling particles of a second ceramic material with the spheroidized particles of the first ceramic material to cause the particles of the second ceramic material to form a coating on the spheroidized particles of the first material. The spheroidized particles coated with the particles of the second ceramic material are then compacted and sintered to form the ceramic-ceramic composite, in which the second ceramic material forms a continuous phase completely surrounding the spheroidized particles of the first ceramic material.
    Type: Application
    Filed: March 22, 2013
    Publication date: July 3, 2014
    Applicants: The Texas A&M University System, Purdue Reseach Foundation
    Inventors: Purdue Reseach Foundation, The Texas A&M University System
  • VIDEO ENCODING AND DECODING METHOD AND APPARATUS USING THE SAME
    Publication number: 20140184741
    Abstract: The present invention is related to a method for moving the position of a base view from an arbitrary GOP (Group Of Pictures) start position to implement an efficient encoding structure in multi-view video encoding. The existing multi-view video encoding method exhibits low encoding efficiency when correlation between the base view and a dependent view is low, since the base view is assumed to be fixed. Moreover, in case the view in a live broadcasting program desired by a producer changes from the base view to another, the user has to consume more bit streams and decoder complexity than those consumed when decoding is performed with respect to the base view. Therefore, to alleviate the drawbacks of the existing multi-view video encoding method, the present invention provides a method for designing syntax elements by which the base view can be moved, thereby supporting an efficient encoding structure.
    Type: Application
    Filed: December 27, 2013
    Publication date: July 3, 2014
    Applicants: Industry-Academic Cooperation Group of Sejong University, Electronics and Telecommunications Research Institute
    Inventors: Jung Won KANG, Ha Hyun LEE, Jin Ho LEE, Jin Soo CHOI, Jin Woong KIM, Jong Ki HAN, Jae Yung LEE
  • LITHIUM ION BATTERY
    Publication number: 20140186717
    Abstract: A lithium ion battery includes a cathode, an anode, and an electrolyte sandwiched between the cathode and the anode. The cathode includes a cathode active material. The anode is spaced from the cathode. The cathode active material includes a sulfur grafted poly(pyridinopyridine). The sulfur grafted poly(pyridinopyridine) includes a poly(pyridinopyridine) matrix and sulfur dispersed in the poly(pyridinopyridine) matrix. The sulfur includes a number of poly-sulfur groups or a number of elemental sulfur particles dispersed in the poly(pyridinopyridine) matrix. The electrolyte is a gel electrolyte.
    Type: Application
    Filed: April 26, 2013
    Publication date: July 3, 2014
    Applicants: HON HAI PRECISION INDUSTRY CO., LTD., Tsinghua University
    Inventors: Li WANG, Xiang-Ming HE, Jian-Jun LI, Jian GAO
  • NITROGEN FIXATION BY TITANIUM DIOXIDE
    Publication number: 20140186254
    Abstract: In various embodiments, the present disclosure provides a method of fixing nitrogen. An amount of titania catalyst is provided and contacted with a feed stream that includes nitrogen. The titania catalyst is heated. The heated titania catalyst fixes nitrogen in the feed stream to form nitrogen products, such as nitrates. The nitrogen products are then removed from the titania catalyst. In some examples, the titania catalyst is treated with a base. In further examples, the catalytic process is carried out in the absence of light for photochemically activating the titania catalyst.
    Type: Application
    Filed: November 7, 2013
    Publication date: July 3, 2014
    Applicant: Board of Regents of the Nevada System of Higher Education, on behalf of the University of Nevada
    Inventors: Glenn C. Miller, Ahmed A. Al-Taani
  • NOVEL ANIONIC POLYALKOXY GROUP COMPRISING SURFACTANTS ON BASIS OF GUERBET-ALCOHOLS, METHOD OF MANUFACTURE AND USE IN ENHANCED OIL RECOVERY (EOR) APPLICATIONS
    Publication number: 20140182851
    Abstract: Compositions and methods of synthesis of anionic surfactants by alkoxylation of a Guerbet alcohol (GA) having 12 to 36 carbon atoms using butylene oxide, and optionally propylene oxide and/or ethylene oxide followed by the incorporation of a terminal anionic group are described herein. The GA of the present invention is made by a facile and inexpensive method that involves high temperature base catalyzed dimerization of alcohols with 6 to 18 carbon atoms. The large hydrophobe ether surfactants of the present invention find uses in enhanced oil recovery (EOR) applications where it is used for solubilization and mobilization of oil and for environmental cleanup. Further, the hydrophobe alkoxylated GA without anionic terminal group can be used as an ultra-high molecular weight non-ionic surfactant.
    Type: Application
    Filed: March 7, 2014
    Publication date: July 3, 2014
    Applicants: BASF SE, Board of Regents, The University of Texas System
    Inventors: Upali P. Weerasooriya, Gary A. Pope, Christian Bittner, Gunter Oetter, Jack F. Tinsley, Christian Spindler, Gabriela Alvarez Jurgenson, Sophie Vogel
  • SINGLE PHOTON SPECTROMETER
    Publication number: 20140186967
    Abstract: A fiberized single photon sensitive spectrometer on a 32-channel PMT sensor is highly sensitive with broad detection dynamic range. The spectrometer enables accurate and high speed detection, identification and analysis of biological samples labeled with multiple fluorescent markers, such as compositions of multi-color fluorescence signals or radiation emitted by multiple fluorescence dyes. A fiberized optical input of the spectrometer allows an easy and efficient coupling to any measurement system based on fiber collection of the analyzed fluorescence. The spectrometer provides highly accurate DNA sequencing. A 32 channel PMT single photon detector has a detection dynamic range of more than 20 bits and has a frame rate of about 3300 frames per second. The dynamic range of the detector's pixels reaches 108 photocounts per second.
    Type: Application
    Filed: September 23, 2013
    Publication date: July 3, 2014
    Applicant: The Research Foundation of State University of New York
    Inventor: Tetyana Gudkova
  • COMBINED MESENCHYMAL STEM CELL TRANSPLANTATION AND TARGETED DELIVERY OF VEGF FOR TREATMENT OF MYOCARDIAL INFARCTION
    Publication number: 20140186431
    Abstract: Compositions and kits useful for the treatment of myocardial infarction comprise (i) P-selectin-targeted carriers (e.g., P-selectin-targeted liposomes, quantum dots or biodegradable nanoparticles) comprising VEGF and (ii) MSCs.
    Type: Application
    Filed: December 4, 2013
    Publication date: July 3, 2014
    Applicant: Temple University - Of The Commonwealth System of Higher Education
    Inventors: Bin Wang, Mohammad F. Kiani, Yuan Tang
  • METHOD FOR PREDICTING THE ATHLETIC PERFORMANCE POTENTIAL OF A SUBJECT
    Publication number: 20140189894
    Abstract: A method for predicting the athletic performance potential of a subject comprising the step of assaying a biological sample from a subject for a genetic variant in linkage disequilibrium with MSTN-66493737 (T/C) SNP. The invention also provides an assay for determining the athletic performance potential of a subject.
    Type: Application
    Filed: February 7, 2014
    Publication date: July 3, 2014
    Applicant: University College Dublin - National University of Ireland, Dublin
    Inventors: Emmeline HILL, David MacHUGH, JingJing GU, Beatrice McGIVNEY
  • PIEZOELECTRIC STACK TRANSDUCER
    Publication number: 20140184021
    Abstract: Provided is a piezoelectric stack transducer. In a transducer portion, a plurality of piezoelectric transducers which output maximum amplitude at different frequencies are continuously stacked. A stacked electrode portion is provided on both surfaces of each of the plurality of continuously stacked piezoelectric transducers and supplies an electric signal so that vibration is generated. In this case, the plurality of piezoelectric transducers have different diameters. According to the present invention, it is possible to implement a piezoelectric stack transducer which exhibits constant amplitude (output) at different frequencies by piezoelectric transducers exhibiting different amplitudes at respective frequencies according to natural frequencies supplementing amplitude of a different piezoelectric transducer.
    Type: Application
    Filed: December 9, 2013
    Publication date: July 3, 2014
    Applicant: Foundation of Soongsil University-Industry Cooperation
    Inventors: Jin Oh Kim, Dae Jong Kim
  • NOVEL OPTICAL LABELING MOLECULES FOR PROTEOMICS AND OTHER BIOLOGICAL ANALYSIS
    Publication number: 20140186875
    Abstract: The invention relates to compositions and methods useful in the labeling and identification of changes in protein levels, changes in enzyme activity, and changes in protein modification. The invention provides for highly soluble optical labeling molecules which are optionally cleavable after separation of mixtures of labeled proteins into components. These optical labeling molecules find utility in a variety of applications, including use in the field of proteomics.
    Type: Application
    Filed: December 30, 2013
    Publication date: July 3, 2014
    Applicant: Montana State University
    Inventors: Edward Dratz, Paul Grieco
  • SYSTEM AND METHOD FOR CLOSED-LOOP PATIENT-ADAPTIVE HEMODYNAMIC MANAGEMENT
    Publication number: 20140188072
    Abstract: A system and method for patient-adaptive hemodynamic management is described. One embodiment includes a system for hemodynamic management including transfusion, volume resuscitation with intravenous fluids, and medications, utilizing monitored hemodynamic parameters including the described dynamic predictors of fluid responsiveness, and including an intelligent algorithm capable of adaptation of the function of the device to specific patients.
    Type: Application
    Filed: November 20, 2013
    Publication date: July 3, 2014
    Applicant: The Regents of the University of California
    Inventors: Joseph B. Rinehart, Maxime Cannesson
  • NOVEL IMMUNOGENIC PROTEINS OF LEPTOSPIRA
    Publication number: 20140186860
    Abstract: The invention provides novel immunogenic proteins LigA and LigB from Leptospira for use in the development of effective vaccines and antibodies, as well as improved diagnostic methods and kits.
    Type: Application
    Filed: April 30, 2012
    Publication date: July 3, 2014
    Applicant: Cornell University
    Inventors: Yung-Fu Chang, Raghavan U.M. Palaniappan
  • RESONANT SENSOR WITH ASYMMETRIC GAPPED CANTILEVERS
    Publication number: 20140183669
    Abstract: A resonant sensor is provided. The resonant sensor may have a structure including a base portion, a mass portion, and a mechanical beam connecting the base portion to the mass portion. In addition, the structure may include a first sensing beam formed from a sensing material responsive to mechanical strain where a gap is formed between the sensing beam and the mechanical beam.
    Type: Application
    Filed: March 25, 2011
    Publication date: July 3, 2014
    Applicant: Wayne State University
    Inventors: Yong Xu, Qinglong Zeng, Yating Hu, Yefa Li, Hongen Tu
  • Small Molecule Antagonists of Phosphatidylinositol-3,4,5-Triphosphate (PIP3) and Uses Thereof
    Publication number: 20140187639
    Abstract: Disclosed are new members of a class of non-lipid small molecule inhibitors which interfere with the interaction between phosphoinositol-3,4,5-triphosphate (PIP3) and pleckstrin homology (PH) domains. These molecules target a broad range of PIP3-dependent signaling events in vitro and exert significant anti-tumor activity in vivo, with improved activity and selectivity toward particular PH domains. The small molecule inhibitors of the invention can be used alone or together with tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) or other cancer medicament to treat cancer. Small molecule inhibitors of the invention act synergistically in combination with TRAIL and with other Akt inhibitors in treating cancer. Pharmaceutical compositions and methods for treating cancer are provided.
    Type: Application
    Filed: December 11, 2013
    Publication date: July 3, 2014
    Applicants: Council of Scientific and Industrial Research, Tufts University
    Inventors: Alexei Degterev, Chepuri Venkata Ramana, Benchun Miao
  • ENGINEERED TAL EFFECTOR PROTEINS WITH ENHANCED DNA TARGETING CAPACITY
    Publication number: 20140186957
    Abstract: The present invention provides compositions and methods for DNA targeting using TAL effectors and TAL effector based proteins, including but not limited to targeted gene regulation and targeted cleavage of cellular chromatin in a region of interest and/or homologous recombination at a predetermined site in cells. Compositions include fusion polypeptides comprising a TAL effector or a TAL effector binding domain in combination with other domains, including but not limited to a cleavage domain. The TAL effector binding domain includes modifications that increase activity of the same and also remove the constraints that the DNA target sequence be preceded by a thymine.
    Type: Application
    Filed: January 3, 2013
    Publication date: July 3, 2014
    Applicants: Fred Hutchinson Cancer Research Center, Iowa State University Research Foundation, Inc.
    Inventors: Adam Joseph Bogdanove, Barry Leonard Stoddard, Philip H. Bradley, Erin Lynn Doyle
  • DYE-SENSITIZED SOLAR CELL AND METHOD FOR MANUFACTURING THE SAME
    Publication number: 20140182669
    Abstract: To provide a dye-sensitized solar cell with suppressed photoelectric conversion efficiency deterioration due to a gap to be possibly be generated between a transparent member on which a light is incident and the dye-sensitized solar cell components. A dye-sensitized solar cell 10 is provided with a dye-sensitized solar cell components unit 14 arranged within a cylindrical transparent member 12, the unit having an electrolyte layer, current collecting electrode 18, and porous semiconductor layer 20 carrying dye cylindrically laminated in this order centering around a cathode electrode layer 16. The cathode electrode layer 16 is a spring body, and the dye-sensitized solar cell components unit 14 is pressed to the transparent member 12 with an elastic restoring force of the spring.
    Type: Application
    Filed: August 7, 2012
    Publication date: July 3, 2014
    Applicants: National University Corporation Kyushu Institute of Technology, NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD.
    Inventors: Shuzi Hayase, Ken-ichi Fujino, Yoshihiro Yamaguchi