Abstract: A system for routing data along a path that is both efficient and secure is provided. A performance and vulnerability routing system selects a path for routing using a joint metric for a link in a network of nodes. The system calculates the joint metric based on a combination of a performance metric and a vulnerability metric of a link. The performance metric for a link indicates the cost of transmitting data over the link, and the vulnerability metric for the link indicates the security of data that is transmitted over the link. The system combines the performance metric and the vulnerability metric to generate the joint metric, which indicates a joint cost of transmitting data. The system then selects paths for transmitting data that tend to minimize the sum of the joint costs of the links along the paths.

Abstract: A lithium battery, including an anode, a cathode, an electrolyte solution and a package structure. The anode includes a material having an oxygen-containing functional group. The cathode and the anode are configured separately, and a housing region is defined between the cathode and the anode. The electrolyte solution is disposed in the housing region, and the electrolyte solution includes water and an additive. The package structure covers the anode, the cathode and the electrolyte solution.

Abstract: Provided is a slot machine which prevents two continuous symbols from coming to be continuous even by conducting a rewriting process. In a case where the one part of the symbol columns is stopped and displayed in the display frame of a symbol display area 4, when a continuous symbol (CHANCE symbol 403) stopped displayed in the display frame of the symbol display area 4 is present in an upstream direction of the scrolling display outside of the display frame of the symbol display area 4, conducted is a delay process in which the rewriting process is conducted for a portion of the symbol column which is present upstream of a position P1 of the continuous symbol (CHANCE symbol 403) in the scrolling display being present in the upstream direction of the scrolling display outside of the display frame of the symbol display area 4.

Abstract: Aspects of the present disclosure are directed to apparatuses and methods involving nanowires having junctions therebetween. As consistent with one or more embodiments, an apparatus includes first and second sets of nanowires, in which the second set overlaps the first set. The apparatus further includes a plurality of nanowire joining recrystallization junctions, each junction including material from a nanowire of the first set that is recrystallized into an overlapping nanowire of the second set.

Abstract: Aspects of the present disclosure are directed to the flow of analytes, particles or other materials. As consistent with one or more embodiments described herein, an apparatus includes a membrane having one or more pores in a membrane. First and second electrodes facilitate electrophoretic flow of analytes through the pore, and a third electrode controls movement of the particles in the pore by modulating the shape of an electric double layer adjacent sidewalls of pore.

Abstract: An integrated electron spin resonance (ESR) circuit chip includes a chip substrate, a transmitter circuit, and a receiver circuit. The transmitter circuit and receiver circuit are disposed on the chip substrate. The transmitter circuit includes an oscillator circuit configured to generate an oscillating output signal and a power amplifier (PA) circuit configured to generate an amplified oscillating output signal based on the oscillating output signal. The receiver circuit receives an ESR signal from an ESR probe. The receiver circuit includes a receiver amplifier circuit configured to generate an amplified ESR signal based on the received ESR signal, a mixer circuit configured to receive the amplified ESR signal and to down-convert the amplified ESR signal to a baseband signal, and a baseband amplifier circuit configured to generate an amplified baseband signal based on the baseband signal.

Abstract: Implants for resurfacing or repairing one or more articular cartilage bearing surfaces of a biological organism include an engineered tissue and a biocompatible porous substrate secured to the engineered tissue for attaching the implant to a native bone of the biological organism. The engineered tissue includes a scaffold containing a biocompatible material, and a plurality of living chondrocytes supported by the scaffold. Methods for culturing chondrocytes for incorporation into a biocompatible implant are provided. A bioreactor for producing functional cartilaginous tissue from a cell-seeded scaffold and a system for producing functional cartilaginous tissue are also provided.

Abstract: A judgment unit judges the pass/fail of DUTs. A power supply circuit has changeable characteristics, and supplies a power supply signal to the DUTs. A condition setting unit performs a pilot test before a main test for the DUTs, and acquires a test condition to be used in the main test. The condition setting unit executes: (a) measuring a first device characteristic value for each of multiple pilot samples sampled from among the DUTs while emulating a power supply characteristic close to what is used in a user environment in which the DUT is actually used; (b) measuring a predetermined second device characteristic value for each of the multiple pilot sample devices while emulating a power supply characteristic close to what is used in a tester environment in which the main test is performed; and (c) determining the test condition based on the first and second device characteristic values.

Abstract: A method of identifying an epileptogenic zone of a subject's brain includes receiving a plurality of electrical signals from a corresponding plurality of surgically implanted electrodes, calculating a first plurality of connectivities between each pair of electrodes based on a portion of each of the plurality of electrical signals corresponding to a first time period, assigning a rank corresponding to each electrode for the first period of time based on the first plurality of connectivities to provide a first plurality of ranks, calculating a second plurality of connectivities between each pair of electrodes based on a portion of each of the plurality of electrical signals corresponding to a second time period, assigning a rank corresponding to each electrode for the second period of time based on the second plurality of connectivities to provide a second plurality of ranks, identifying a cluster of electrodes among the plurality of electrodes based on relative changes between the first plurality of ranks fro

Abstract: A semiconductor epitaxial structure is provided. The semiconductor epitaxial structure includes a substrate, a doped semiconductor epitaxial layer, and a carbon nanotube layer. The doped semiconductor epitaxial layer is located on the substrate. The carbon nanotube layer is located between the substrate and the doped semiconductor epitaxial layer. The carbon nanotube layer can be a carbon nanotube film drawn from a carbon nanotube array and including a number of successive and oriented carbon nanotubes joined end-to-end by van der Waals attractive force therebetween.

Abstract: A combined teleoperative-cooperative controllable robotic system includes a robotic actuator assembly, a control system adapted to communicate with the robotic actuator assembly, and a teleoperation unit adapted to communicate with the control system. The control system is configured to control at least a first portion of the robotic actuator assembly in response to at least one of a force or a torque applied to at least a second portion of the robotic actuator assembly by a first user for cooperative control. The control system is further configured to control at least a third portion of the robotic actuator assembly in response to input by a second user from the teleoperation unit for teleoperative control.

Abstract: The present invention provides reagents, methods and systems for predicting the inhibitory activity of an antibody or variant thereof comprising: determining a binding affinity of the antibody or variant thereof to a Fc activating receptor; determining a binding affinity of the antibody or variant thereof to a Fc inhibitory receptor, and calculating the ratio of said activating binding affinity to said inhibitory binding affinity (A/I ratio), wherein the magnitude of said ratio is less than one (1).

Abstract: A non-enteric coated pharmaceutical composition having an enhanced bioavailability comprising an acid-labile active ingredient and a nanolized biocompatible polymer, wherein the acid-labile active ingredient is mixed with and trapped by the nanolized biocompatible polymer, and the acid-labile active ingredient is sustainably released from the nanolized biocompatible polymer.

Abstract: This invention relates generally to stimulating neurogenesis (e.g., post-natal neurogenesis, e.g., post-natal hippocampal neurogenesis) and protection from neuron cell death.

Abstract: On the slot machine, a slot game including a base game and free games is caused to proceed on a display. On the base game reel strips, on all of a plurality of reels, symbols whose each kind is the same, other than feature symbols and wild symbols, are arranged in succession. On the free game reel strips, on all of a plurality of reels, symbols whose each kind is the same, other than the feature symbols and the wild symbols, are arranged in succession and in addition thereto, only in a case of top symbols whose payout multiplying factor is the highest, the top symbols whose number is larger than a number of top symbols displayed on the base game reel strips are arranged in succession.

Abstract: A map symbol to be substituted with another symbol is included in a symbol set for a game. When two or more map symbols are included in a symbol arrangement, symbols in a subset of the symbol set are scrolled on display blocks occupied by the map blocks in a simultaneous manner. Each of the map symbols is substituted with another symbol in the subset, thereby forming a finalized symbol arrangement. A payout process is performed based on the finalized symbol arrangement.

Abstract: A device, system, and method for isolating a ventilator from one or more patients in which the delivery conditions of gas delivered to an isolation device from a ventilator may drive the delivery of breathing-gas delivered to one or more patients, the breathing-gas having the same or different delivery conditions. In one embodiment, an isolation device may have a housing and a movable partition. The movable partition may be joined to the housing, The movable partition may have a patient side on a first side of the partition and an actuating side on a second side of the partition. The isolation device may include an inlet pressure regulator on the actuating side and/or an exhaust pressure regulator on the patient side. These regulators may alter the delivery conditions (including, but not limited to, pressure and volume) of breathing-gas delivered to a patient.

Abstract: An exosomal composition is provided that comprises a therapeutic agent encapsulated by an exosome. The therapeutic agent can be a phytochemical agent, a chemotherapeutic agent, or a Stat3 inhibitor. Pharmaceutical compositions comprising the exosomal compositions are also provided. Methods for treating an inflammatory disease or a cancer are further provided and include administering an effective amount of an exosomal composition to a subject in need thereof to thereby treat the inflammatory disorder or the cancer.

Abstract: The present invention provides compositions and methods for the pretreatment of lignocellulosic material. The present invention further provides for pretreated lignocellulosic material that can be used to produce useful products, such as fermentable sugars.

Abstract: Here provided is a method for regulating retinal endothelial cell viability in a mammal by administering to the mammal a therapeutically effective amount of a quinic acid analog. The method may be applied to prevent, treat or cure pathological conditions of retinal endothelial cells associated with radiation retinopathy, diabetic retinopathy and chemotherapy for retinoblastoma.